The binding motifs displayed here are calculated from the top 0.1% (EL) and top 1% (BA) predicted
binder from a pool of 1,000,000 random natural 9mer peptides. The difference in
the samplede peptide space is chosen to reflect the difference in the
volume of the space of naturally presented ligands (0.1%) and MHC binders (1%).
CITATIONS
For publication of results, please cite:
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NetH2pan: A Computational Tool to Guide MHC peptide prediction on Murine Tumors
Christa I. DeVette, Massimo Andreatta, Wilfried Bardet, Steven J. Cate, Vanessa I. Jurtz, Kenneth W. Jackson, Alana L. Welm, Morten Nielsen, William H. Hildebrand
Cancer Immunology Research (2018) DOI: 10.1158/2326-6066.CIR-17-0298
Full text
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NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data
Vanessa Jurtz, Sinu Paul, Massimo Andreatta, Paolo Marcatili, Bjoern Peters and Morten Nielsen
The Journal of Immunology (2017) ji1700893; DOI: 10.4049/jimmunol.1700893
Full text
DATA RESOURCES
Data resources used to develop this server was obtained from
- IEDB database.
- Quantitative peptide binding data were obtained
from the IEDB database.
- IMGT/HLA database. Robinson J, Malik A, Parham P, Bodmer JG,
Marsh SGE: IMGT/HLA - a sequence database for the human major histocompatibility complex. Tissue Antigens (2000),
55:280-287.
- MHC protein sequences were obtained from the IMGT/HLA database (version 3.1.0).