Submission

Submit data

For detailed webserver instructions, see the instructions page.

MIRROR Use DiscoTope-3.0 on BioLib if this server is heavily loaded.

1. Input structure(s) (file upload or PDB ID list)

a) A file from your local disk containing a protein structure in PDB format, or a .zip file containing structures in PDB format (maximum 50):

b) A list of protein structure IDs (PDB or UniProt/AlphaFoldDB IDs):

2. Input structure type

Solved structure (default) AlphaFold structure

Note: All chains will be processed individually for any ID or input file in PDB format.
Confidentiality: The input files are kept confidential and will be deleted after processing.
Warning: External Communication: The application may access the following hosts during runtime, including sending and receiving data. Make sure you trust the below web servers as your input data may be revealed to them:
alphafold.ebi.ac.uk
files.rcsb.org

Citations

For publication of results, please cite:

DiscoTope-3.0: Improved B-cell epitope prediction using AlphaFold2 modeling and inverse folding latent representations
Magnus Haraldson Høie, Frederik Steensgaard Gade, Julie Maria Johansen, Charlotte Würtzen, Ole Winther, Morten Nielsen, Paolo Marcatili. Journal (2023). doi: doi

Results are displayed using:

Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures
David Sehnal, Sebastian Bittrich, Mandar Deshpande, Radka Svobodová, Karel Berka, Václav Bazgier, Sameer Velankar, Stephen K Burley, Jaroslav Koča, Alexander S Rose. Nucleic Acids Research (2021). doi: 10.1093/nar/gkab314