ABC-type Fe3+-hydroxamate transport system, periplasmic component
Tfp pilus assembly protein, pilus retraction ATPase PilT
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
Bacterial cell division membrane protein
Translation initiation factor 2 (IF-2; GTPase)
ATPase components of ABC transporters with duplicated ATPase domains
Permeases of the major facilitator superfamily
Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Putative effector of murein hydrolase LrgA
Sugar transferases involved in lipopolysaccharide synthesis
ABC-type transport system, involved in lipoprotein release, permease component
Uncharacterized membrane protein (homolog of Drosophila rhomboid)
Uncharacterized protein conserved in bacteria
Ribonuclease P; protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
ABC-type Fe3+ transport system, permease component
ABC-type sugar transport systems, ATPase components
ABC-type Fe3+ transport system, periplasmic component
Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Dioxygenases related to 2-nitropropane dioxygenase
Predicted Zn-dependent hydrolases of the beta-lactamase fold
Glycosyltransferases, probably involved in cell wall biogenesis
Glycosyltransferases involved in cell wall biogenesis
Predicted membrane protein involved in D-alanine export
Bacterial surface proteins containing Ig-like domains
Uncharacterized protein conserved in cyanobacteria
Putative primosome component and related proteins
Uncharacterized protein, involved in the regulation of septum location
ATPases involved in chromosome partitioning
Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
Na+-dependent transporters of the SNF family
Transcriptional regulator, contains sigma factor-related N-terminal domain
Carbon starvation protein, predicted membrane protein
ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
ABC-type Fe3+-siderophore transport system, permease component
ATPases with chaperone activity, ATP-binding subunit
Transcriptional regulators, similar to M. xanthus CarD
Integral membrane protein (PIN domain superfamily)
Transcriptional regulators of sugar metabolism
Membrane proteins related to metalloendopeptidases
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
Membrane-associated lipoprotein involved in thiamine biosynthesis
FF ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F containing the extramembraneous catalytic core and F containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
Arsenate reductase and related proteins, glutaredoxin family
Actin-like ATPase involved in cell division
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
Cell division protein FtsI/penicillin-binding protein 2
Electron transfer flavoprotein, beta subunit
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ABC-type uncharacterized transport system, periplasmic component
ABC-type uncharacterized transport system, permease component
ABC-type uncharacterized transport system, ATPase component
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
Actin-like ATPase involved in cell morphogenesis
Acetyltransferases, including N-acetylases of ribosomal proteins
ABC-type sugar transport systems, permease components
Carbon storage regulator (could also regulate swarming and quorum sensing)
Protein involved in regulation of cell shape
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
Zn-dependent protease with chaperone function
DNA-directed RNA polymerase, beta subunit/140 kD subunit
DNA-directed RNA polymerase, beta' subunit/160 kD subunit
Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
Outer membrane protein/protective antigen OMA87
Predicted endonuclease distantly related to archaeal Holliday junction resolvase
NifU homolog involved in Fe-S cluster formation
Lactate dehydrogenase and related dehydrogenases
Lactoylglutathione lyase and related lyases
Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit
ABC-type (unclassified) transport system, ATPase component
Carbamoylphosphate synthase large subunit (split gene in MJ)
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
NAD/FAD-utilizing enzyme apparently involved in cell division
TRAP-type uncharacterized transport system, fused permease components
ATP-dependent protease Clp, ATPase subunit
Superfamily II DNA/RNA helicases, SNF2 family
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
DNA polymerase sliding clamp subunit (PCNA homolog)
NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
Predicted dehydrogenases and related proteins
Predicted ATPase involved in cell division
Predicted DNA-binding protein with PD1-like DNA-binding motif
Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
FKBP-type peptidyl-prolyl cis-trans isomerases 1
Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
Hydroxyethylthiazole kinase, sugar kinase family
Beta-propeller domains of methanol dehydrogenase type
ABC-type spermidine/putrescine transport systems, ATPase components
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
Uncharacterized metal-binding protein conserved in archaea
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Recombinational DNA repair ATPase (RecF pathway)
Uncharacterized conserved protein, contains double-stranded beta-helix domain
Helicase subunit of the DNA excision repair complex
ABC-type sugar transport system, permease component
dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
Outer membrane receptor proteins, mostly Fe transport
ATPase components of various ABC-type transport systems, contain duplicated ATPase
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
ABC-type dipeptide transport system, periplasmic component
DNA-directed RNA polymerase, alpha subunit/40 kD subunit
ABC-type branched-chain amino acid transport systems, periplasmic component
Branched-chain amino acid ABC-type transport system, permease components
ABC-type branched-chain amino acid transport system, permease component
ABC-type branched-chain amino acid transport systems, ATPase component
Hemolysins and related proteins containing CBS domains
Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain
Predicted double-stranded RNA/RNA-DNA hybrid binding protein
Predicted hydrolases of the HAD superfamily
Methylase of polypeptide chain release factors
Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
DNA segregation ATPase FtsK/SpoIIIE and related proteins
Cyclopropane fatty acid synthase and related methyltransferases
Outer membrane receptor for ferrienterochelin and colicins
ABC-type uncharacterized transport systems, ATPase components
NAD-dependent DNA ligase (contains BRCT domain type II)
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
Site-specific recombinases, DNA invertase Pin homologs
Type I restriction-modification system methyltransferase subunit
Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
SufE protein probably involved in Fe-S center assembly
Holliday junction resolvasome, DNA-binding subunit
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters
Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
Nuclease subunit of the excinuclease complex
Putative transcriptional regulator, homolog of Bvg accessory factor
Cytotoxic translational repressor of toxin-antitoxin stability system
Protein involved in protein polymerization
Phosphatidylglycerophosphatase A and related proteins
Uncharacterized protein, possibly involved in aromatic compounds catabolism
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
Predicted P-loop ATPase and inactivated derivatives
ABC-type transport system involved in Fe-S cluster assembly, ATPase component
Predicted branched-chain amino acid permeases (azaleucine resistance)
Predicted branched-chain amino acid permease (azaleucine resistance)
Predicted membrane GTPase involved in stress response
Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
Putative translation initiation inhibitor, yjgF family
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
Acetolactate synthase, small (regulatory) subunit
ABC-type phosphate transport system, periplasmic component
ABC-type maltose transport systems, permease component
Peptidylarginine deiminase and related enzymes
Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
ABC-type transport system involved in Fe-S cluster assembly, permease component
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
Permeases of the drug/metabolite transporter (DMT) superfamily
Predicted exonuclease of the beta-lactamase fold involved in RNA processing
Predicted signal transduction protein with a C-terminal ATPase domain
Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
Negative regulator of genetic competence, sporulation and motility
FKBP-type peptidyl-prolyl cis-trans isomerases 2
Histone acetyltransferase HPA2 and related acetyltransferases
Putative virion core protein (lumpy skin disease virus)
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
Anti-Sigma regulatory factor, serine/threonine protein kinase
Uncharacterized conserved protein (small basic protein)
D-alanine-D-alanine ligase and related ATP-grasp enzymes
Cell wall-associated hydrolases (invasion-associated proteins)
Type IV secretory pathway, VirB4 components
GTPase SAR1 and related small G proteins
Cystathionine beta-lyase family protein involved in aluminum resistance
SOS-response transcriptional repressors (RecA-mediated autopeptidases)
ABC-type phosphate transport system, permease component
ABC-type phosphate transport system, ATPase component
Predicted oxidoreductase related to nitroreductase
Metal-dependent hydrolases of the beta-lactamase superfamily I
ABC-type antimicrobial peptide transport system, permease component
Predicted RNA-binding protein (contains KH domain)
ATP-dependent Lon protease, bacterial type
Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ABC-type metal ion transport system, permease component
NTP pyrophosphohydrolases including oxidative damage repair enzymes
Mannosyltransferase OCH1 and related enzymes
7-keto-8-aminopelargonate synthetase and related enzymes
Low specificity phosphatase (HAD superfamily)
Trk-type K+ transport systems, membrane components
Nitrogenase molybdenum-iron protein, alpha and beta chains
Histidinol phosphatase and related hydrolases of the PHP family
Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
Type II secretory pathway, component PulF
Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
Predicted GTPase, probable translation factor
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
Nucleotide-binding protein implicated in inhibition of septum formation
Predicted NADH:ubiquinone oxidoreductase, subunit RnfE
Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
TRAP-type uncharacterized transport system, periplasmic component
Uncharacterized protein related to glutamine synthetase
Predicted RNA-binding protein homologous to eukaryotic snRNP
Predicted metal-dependent hydrolase of the TIM-barrel fold
Periplasmic serine proteases (ClpP class)
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
ABC-type sugar transport system, periplasmic component
5'-3' exonuclease (including N-terminal domain of PolI)
Type II secretory pathway, pullulanase PulA and related glycosidases
Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component
Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Predicted metal-binding, possibly nucleic acid-binding protein
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
NAD(FAD)-utilizing enzyme possibly involved in translation
Membrane protein involved in the export of O-antigen and teichoic acid
Protein involved in alginic acid catabolic process
Regulator of polyketide synthase expression
Na+/H+ antiporter NhaD and related arsenite permeases
F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
DNA polymerase beta domain protein region
ABC-type metal ion transport system, ATPase component
ABC-type multidrug transport system, ATPase and permease components
Phosphate starvation-inducible protein PhoH, predicted ATPase
ABC-type cobalt transport system, permease component CbiQ and related transporters
Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
Predicted membrane-associated Zn-dependent proteases 1
Flagellin and related hook-associated proteins
ABC-type spermidine/putrescine transport system, permease component I
ABC-type spermidine/putrescine transport system, permease component II
NADPH-dependent glutamate synthase beta chain and related oxidoreductases
Threonine dehydrogenase and related Zn-dependent dehydrogenases
TRAP-type C4-dicarboxylate transport system, large permease component
TRAP-type C4-dicarboxylate transport system, small permease component
TRAP-type C4-dicarboxylate transport system, periplasmic component
Predicted divalent heavy-metal cations transporter
ABC-type polysaccharide transport system, permease component
Predicted hydrolase of the metallo-beta-lactamase superfamily
Na+/melibiose symporter and related transporters
Iron only hydrogenase large subunit, C-terminal domain
ABC-type polar amino acid transport system, ATPase component
ABC-type amino acid transport system, permease component
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
Predicted NADH:ubiquinone oxidoreductase, subunit RnfG
Predicted NADH:ubiquinone oxidoreductase, subunit RnfD
Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
Lipid A core - O-antigen ligase and related enzymes
Plasmid maintenance system antidote protein
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
Succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family
Predicted kinase related to dihydroxyacetone kinase
Predicted methylated DNA-protein cysteine methyltransferase
Disulfide bond chaperones of the HSP33 family
Osmosensitive K+ channel histidine kinase
ATPase related to the helicase subunit of the Holliday junction resolvase
Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
ATPase involved in DNA replication initiation
Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen
Response regulator of the LytR/AlgR family
ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
Ribosomal protein S4 and related proteins
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain
ABC-type uncharacterized transport system involved in gliding motility, auxiliary component
Uncharacterized homolog of phage Mu protein gp47
Uncharacterized protein containing LysM domain
DNA polymerase III, alpha subunit (gram-positive type)
Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
Serine phosphatase RsbU, regulator of sigma subunit
May be a glycosyltransferase involved in the transfer of UDP-GalF to the lipopolysaccharide
Cytoplasmicmembrane, score:9.99; NOG33934 non supervised orthologous group protein
Lysophospholipase L1 and related esterases
Alpha-glucosidases, family 31 of glycosyl hydrolases
Predicted ATP-binding protein involved in virulence
Dna-Directed RNA polymerase, omega subunit
Kef-type K+ transport systems, membrane components
Primosomal protein N' (replication factor Y) - superfamily II helicase
ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
Predicted DNA-binding protein with the Helix-hairpin-helix motif
Type II restriction enzyme, methylase subunits
4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
Recombinational DNA repair protein (RecF pathway)
Multisubunit Na+/H+ antiporter, MnhC subunit
Multisubunit Na+/H+ antiporter, MnhB subunit
Multiple resistance and pH regulation protein F
Multisubunit Na+/H+ antiporter, MnhE subunit
Type II secretory pathway, component PulD
Metal-dependent proteases with possible chaperone activity
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
Protease subunit of ATP-dependent Clp proteases
ABC-type sulfate/molybdate transport systems, ATPase component
ABC-type uncharacterized transport system, permease and ATPase components
Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain
DNA-directed RNA polymerase specialized sigma subunit
Flagellar biosynthesis pathway, component FliR
Flagellar biosynthesis pathway, component FliQ
Dihydropteroate synthase and related enzymes
Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
Protein involved in lipopolysaccharide biosynthetic process
ABC-type Mn2+/Zn2+ transport systems, permease components
Dihydroorotase and related cyclic amidohydrolases
Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
ABC-type multidrug transport system, ATPase component
Fucose 4-O-acetylase and related acetyltransferases
DNA mismatch repair enzyme (predicted ATPase)
ABC-type transport system involved in resistance to organic solvents, ATPase component
ABC-type polysaccharide/polyol phosphate transport system, ATPase component
ABC-type polysaccharide/polyol phosphate export systems, permease component
Membrane protease subunits, stomatin/prohibitin homologs
Galactose mutarotase and related enzymes
Response regulator containing a CheY-like receiver domain and a GGDEF domain
Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
Holliday junction resolvasome, endonuclease subunit
Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
Chemotaxis protein; stimulates methylation of MCP proteins
Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
Flagellar biosynthesis pathway, component FlhA
Flagellar biosynthesis pathway, component FlhB
Flagellar biosynthesis/type III secretory pathway lipoprotein
Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
Predicted ATPase with chaperone activity
Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
Large exoproteins involved in heme utilization or adhesion
Predicted metal-dependent phosphoesterases (PHP family)
Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
Predicted membrane protein, hemolysin III homolog
Mn2+ and Fe2+ transporters of the NRAMP family
F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
Molecular chaperone (small heat shock protein)
Uncharacterized protein related to capsule biosynthesis enzymes
K+ transport systems, NAD-binding component
Nucleotidyltransferase/DNA polymerase involved in DNA repair
McrBC 5-methylcytosine restriction system component
F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
ABC-type antimicrobial peptide transport system, ATPase component
Predicted membrane-associated HD superfamily hydrolase
Uncharacterized protein conserved in bacteria with the myosin-like domain
Cobalamin biosynthesis protein CobN and related Mg-chelatases
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
Protein found in conjugate transposon TraN
5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
Transposase and inactivated derivatives, IS30 family
Outer membrane protein, involved in nutrient binding
Required for maturation of 30S ribosomal subunits (By similarity)
Transcription-repair coupling factor (superfamily II helicase)
Coenzyme F420-reducing hydrogenase, beta subunit
Transcriptional activator of acetoin/glycerol metabolism
Putative periplasmic protein kinase ArgK and related GTPases of G3E family
Uncharacterized conserved protein, contains S4-like domain
Uncharacterized homolog of plant Iojap protein
Penicillin-binding protein-related factor A, putative recombinase
Methylase of chemotaxis methyl-accepting proteins
Cytochrome bd-type quinol oxidase, subunit 2
RimM protein, required for 16S rRNA processing
Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
Uncharacterized membrane protein, possible Na+ channel or pump
DNA binding domain protein, excisionase family
Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
NADH:ubiquinone oxidoreductase subunit 4 (chain M)
Low complexity protein, contains internal repeats QQVlQQDVAQLQAG
ABC-type metal ion transport system, periplasmic component/surface antigen
Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
Phosphoglycerate dehydrogenase and related dehydrogenases
ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)
Flagellar biosynthesis/type III secretory pathway ATPase
Addiction module toxin, RelE/StbE family protein
NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
Inactive homolog of metal-dependent proteases, putative molecular chaperone
Metal-dependent hydrolases of the beta-lactamase superfamily III
Uncharacterized protein predicted to be involved in DNA repair
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
ABC-type xylose transport system, periplasmic component
Pantothenate kinase; catalyzes the formation of -4'-phosphopantothenate from -pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A
ABC-type oligopeptide transport system, ATPase component
ABC-type oligopeptide transport system, periplasmic component
ABC-type Mn/Zn transport systems, ATPase component
Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ABC-type cobalt transport system, ATPase component
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
Aldo/keto reductases, related to diketogulonate reductase
ABC-type sugar transport system, ATPase component
Transglutaminase-like enzymes, putative cysteine proteases
Uncharacterized protein containing a Zn-finger-like domain
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
Uncharacterized ABC-type transport system, permease componentNOG123520
Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
Protein involved in ciliary or flagellar motility
Uncharacterized protein, homolog of phage Mu protein gp30
Outer membrane protein involved in nutrient binding
Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain
FOG: Transposase and inactivated derivatives
Glycerol dehydrogenase and related enzymes
Periplasmic protein involved in polysaccharide export
Glycine cleavage system T protein (aminomethyltransferase)
Methionine synthase I, cobalamin-binding domain
Mg/Co/Ni transporter MgtE (contains CBS domain)
Predicted acetyltransferase involved in intracellular survival and related acetyltransferases
Predicted nucleic-acid-binding protein implicated in transcription termination
Cytosine deaminase and related metal-dependent hydrolases
Preprotein translocase subunit SecA (ATPase, RNA helicase)
Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB
Cobalamin biosynthesis protein CbiK, Co2+ chelatase
Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
Zn-dependent dipeptidase, microsomal dipeptidase homolog
DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
Transcriptional regulator of heat shock gene
Predicted esterase of the alpha-beta hydrolase superfamily
ABC-type Na+ efflux pump, permease component
Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
Predicted signal transduction protein containing EAL and modified HD-GYP domains
Uncharacterized membrane protein, required for spore maturation in B.subtilis.
NAD-dependent protein deacetylases, SIR2 family
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
Penicillin V acylase and related amidases
Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
Molecular chaperone GrpE (heat shock protein)
Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
Uncharacterized protein involved in stress response
Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain
Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC
Mammalian cell entry related domain protein
Predicted periplasmic ligand-binding sensor domain
Type IV secretory pathway, VirD4 components
ABC-type sulfate transport system, periplasmic component
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
Transcriptional regulator, XRE family protein
High-affinity K+ transport system, ATPase chain B
Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
Glycosyl hydrolase BNR repeat- containing
ABC-type transport system involved in multi-copper enzyme maturation, permease component
Outer membrane cobalamin receptor protein
Protein found in conjugate transposon TraK
GTPases - translation elongation factors
Integral membrane protein, interacts with FtsH
Predicted ATP-dependent endonuclease of the OLD family
DnaJ-class molecular chaperone with C-terminal Zn finger domain
Sec-independent protein secretion pathway component TatC
Metal-dependent hydrolases of the beta-lactamase superfamily II
DNA-binding protein, stimulates sugar fermentation
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
Serine kinase of the HPr protein, regulates carbohydrate metabolism
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
DNA uptake protein and related DNA-binding proteins
Predicted kinase related to galactokinase and mevalonate kinase
NADH:ubiquinone oxidoreductase 24 kD subunit
Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins
Signal transduction histidine kinase regulating citrate/malate metabolism
Membrane-bound serine protease (ClpP class)
Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
Predicted transcriptional regulator containing the HTH domain
Glycine cleavage system H protein (lipoate-binding)
Protein distantly related to bacterial ferritins
Non-ribosomal peptide synthetase modules and related proteins
LuxS protein involved in autoinducer AI2 synthesis
Anti-sigma regulatory factor (Ser/Thr protein kinase)
Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
Glucoamylase and related glycosyl hydrolases
Superfamily I DNA and RNA helicases and helicase subunits
Predicted phosphoglycerate mutase, AP superfamily
Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
H+/gluconate symporter and related permeases
Beta-lactamase class C and other penicillin binding proteins
Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation
Alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen
Sulfate permease and related transporters (MFS superfamily)
Response regulator containing a CheY-like receiver domain and an HD-GYP domain
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
Vitamin B12 dependent methionine synthase, activation
ABC-type transport system involved in cytochrome c biogenesis, permease component
Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Protein involved in toxin biosynthetic process
Translation initiation factor 1 (eIF-1/SUI1) and related proteins
Response regulator containing CheY-like receiver and SARP domains
Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
Predicted oxidoreductases of the aldo/keto reductase family
NADH:ubiquinone oxidoreductase subunit 2 (chain N)
NADH:ubiquinone oxidoreductase subunit 6 (chain J)
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
NADH:ubiquinone oxidoreductase subunit 1 (chain H)
NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
NADH:ubiquinone oxidoreductase subunit 3 (chain A)
Phosphotransferase system, galactitol-specific IIC component
ABC-type multidrug transport system, permease component
Predicted Zn-dependent proteases and their inactivated homologs
Predicted drug exporters of the RND superfamily
3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
Uncharacterized protein containing piwi/argonaute domain
Outer membrane lipoprotein carrier protein LolA
Phytoene dehydrogenase and related proteins
Peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
Gp:Ae016928_177 [Bacteroides thetaiotaomicron VPI-5482], percent identity protein
DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
Predicted exporters of the RND superfamily
Transcriptional regulator, MarR family protein
ABC-type molybdate transport system, permease component
Uncharacterized protein required for formate dehydrogenase activity
Outer membrane protein and related peptidoglycan-associated (lipo)proteins
Abortive infection bacteriophage resistance protein
Methylase involved in ubiquinone/menaquinone biosynthesis
Phosphotransferase, for other substituted phosphate groups
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
Sporulation protein and related proteins
Glycoside hydrolase family 2 sugar binding
Transcriptional activator, adenine-specific DNA methyltransferase
Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
Predicted RNA-binding protein, contains TRAM domain
Predicted ornithine cyclodeaminase, mu-crystallin homolog
Nitric oxide reductase activation protein
Saccharopine dehydrogenase and related proteins
Negative regulator of beta-lactamase expression
Alpha-Galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
Holliday junction resolvasome, helicase subunit
4Fe-4S ferredoxin iron-sulfur binding domain protein
Predicted sugar phosphate isomerase involved in capsule formation
Predicted Rossmann fold nucleotide-binding protein
ATP-utilizing enzymes of the PP-loop superfamily
Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
Protein involved in chromosome condensation
Hydrolases of the alpha/beta superfamily
Stress responsive alpha-beta barrel protein
Uncharacterized proteins of the AP superfamily
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits
Protein involved in initiation of plasmid replication
Predicted hydrolase of alkaline phosphatase superfamily
Uncharacterized protein containing caspase domain
Uncharacterized stress protein (general stress protein 26)
Phage terminase-like protein, large subunit
Predicted small molecule binding protein (contains 3H domain)
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
Protein involved in cell redox homeostasis
XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein
Predicted NADH:ubiquinone oxidoreductase, subunit RnfA
Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
Chemotaxis protein histidine kinase and related kinases
Uncharacterized protein involved in copper resistance
ABC-type Na+ transport system, ATPase component
Uncharacterized enzyme of thiazole biosynthesis
Chemotaxis protein CheC, inhibitor of MCP methylation
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ABC-type sulfate transport system, permease component
N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
Stress responsive alpha-beta barrel domain protein
Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase
Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog
Integral membrane protein CcmA involved in cell shape determination
Flagellar biosynthesis pathway, component FliP
Flagellar biosynthesis/type III secretory pathway protein
Phosphotransferase system cellobiose-specific component IIC
Putative Zn-dependent protease, contains TPR repeats
Coagulation factor 5/8 type domain protein
Response regulator with putative antiterminator output domain
Predicted metal-dependent protease of the PAD1/JAB1 superfamily
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
Phage shock protein A (IM30), suppresses sigma54-dependent transcription
Transcriptional regulator, Xre family protein
Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
Uncharacterized protein with conserved CXXC pairs
4-aminobutyrate aminotransferase and related aminotransferases
Uncharacterized lipoprotein NlpE involved in copper resistance
Predicted hydrolase of the alpha/beta superfamily
Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
Protein involved in rhamnose metabolic process
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
ATP phosphoribosyltransferase involved in histidine biosynthesis
Predicted HD superfamily hydrolase involved in NAD metabolism
Cell wall hydrolyses involved in spore germination
Predicted metal-dependent hydrolase with the TIM-barrel fold
ABC-type taurine transport system, periplasmic component
GTPases - Sulfate adenylate transferase subunit 1
GTPase subunit of restriction endonuclease
Phosphate-Selective porin O and P protein
Trk-Type K+ transport systems membrane protein
Short-chain dehydrogenases of various substrate specificities
Kef-type K+ transport systems, predicted NAD-binding component
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Clindamycin resistance transfer factor BtgB
Predicted inhibitor of MCP methylation, homolog of CheC
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
Uncharacterized protein involved in tellurite resistance
ABC-type phosphate/phosphonate transport system, permease component
Predicted hydrolase of the HAD superfamily
Recombinational DNA repair protein (RecE pathway)
Predicted membrane protein, putative toxin regulator
O-Methyltransferase involved in polyketide biosynthesis
Integral membrane protein possibly involved in chromosome condensation
Prophage maintenance system killer protein
Type IV secretory pathway, VirD2 components (relaxase)
DNA-binding ferritin-like protein (oxidative damage protectant)
Uncharacterized enzyme involved in inositol metabolism
Predicted sugar phosphatases of the HAD superfamily
Hydrolase, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Periplasmic component of the Tol biopolymer transport system
Alkyl hydroperoxide reductase, large subunit
Enterochelin esterase and related enzymes
Mu-like prophage DNA circulation protein
Ribosomal protein L25 (general stress protein Ctc)
Protein involved in intein-mediated protein splicing
Glycosyl transferases, related to UDP-glucuronosyltransferase
Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)
ABC-type proline/glycine betaine transport systems, ATPase components
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
Protein involved in DNA conformation change
Superfamily II helicase and inactivated derivatives
Predicted carbamoyl transferase, NodU family
Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
Coiled-Coil domain containing 147 protein
Putative homoserine kinase type II (protein kinase fold)
Regulators of stationary/sporulation gene expression
Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
Glycosyltransferase involved in LPS biosynthesis
Fucose dissimilation pathway protein FucU
Antibiotic-Transport integral membrane leucine and valine rich protein ABC transporter
Carbon dioxide concentrating mechanism/carboxysome shell protein
Fe-S oxidoreductase, related to NifB/MoaA family
Twin-Arginine translocation pathway signal protein
Histidinol phosphatase and related phosphatases
Protein involved in response to auxin stimulus
16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
ABC transporter, ATP-binding protein-related protein
Cytochrome bd-type quinol oxidase, subunit 1
Phosphotransferase system, mannitol-specific IIBC component
Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
Arac family transcriptional regulator protein
Aspartate aminotransferase; catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
Uncharacterized protein containing a ferredoxin domain
NADH:flavin oxidoreductases, Old Yellow Enzyme family
Transcriptional repressor of class III stress genes
Membrane protein implicated in regulation of membrane protease activity
Outer membrane chaperone Skp (OmpH) protein
Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
ABC-type sugar transport system, auxiliary component
Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
Protein involved in response to aluminum ion
NADPH:quinone reductase and related Zn-dependent oxidoreductases
Predicted secreted protein containing a PDZ domain
Septum formation topological specificity factor
ABC-type metal ion transport system, periplasmic component/surface adhesin
Identified by match to protein family HMM PF05582; match to protein family HMM TIGR02855
Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC
ABC-type enterochelin transport system, periplasmic component
ABC-type enterochelin transport system, ATPase component
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
ABC-type molybdate transport system, periplasmic component
GMP synthase - Glutamine amidotransferase domain
Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
N-terminal domain of molybdenum-binding protein
Fibronectin type 3 domain-containing protein
Exonuclease, RNase T and DNA polymerase III
Uncharacterized protein, possibly involved in motility
Binding-Protein-Dependent transport systems inner membrane component
DNA polymerase I - 3'-5' exonuclease and polymerase domains
Predicted nucleic acid-binding protein, contains PIN domain
Oxidoreductase, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Putative NADPH-quinone reductase (modulator of drug activity B)
Protein involved in catabolism of external DNA
Membrane transporters of cations and cationic drugs
Uncharacterized conserved protein related to dihydrodipicolinate reductase
Mu-like prophage tail sheath protein gpL
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
Helix_Turn_Helix gluconate operon transcriptional repressor
Predicted periplasmic or secreted lipoprotein
Phosphate transport regulator (distant homolog of PhoU)
Sporulation sigma-E factor processing peptidase
Type II restriction-modification system restriction subunit
Cytidine deaminase; Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
Predicted choline kinase involved in LPS biosynthesis
Twinkle protein, mitochondrial Precursor (EC 3.6.1.-)
Ribosome biogenesis GTP-binding protein YsxC; binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
Universal stress protein UspA and related nucleotide-binding proteins
ABC-type transport system involved in resistance to organic solvents, permease component
Uncharacterized membrane protein, putative virulence factor
Capsular polysaccharide synthesis enzyme CpsG lipid A core - O-antigen ligase
Predicted RNA binding protein (contains ribosomal protein S1 domain)
Inner membrane protein involved in colicin E2 resistance
Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
Trehalose and maltose hydrolases (possible phosphorylases)
Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes
Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
Purine-cytosine permease and related proteins
Electron transfer flavoprotein, alpha subunit
Addiction module antitoxin, RelB/DinJ family protein
Uncharacterized conserved protein related to MYG1 family
ABC-type proline/glycine betaine transport systems, permease component
Alpha-tubulin suppressor and related RCC1 domain-containing proteins
Predicted metal-sulfur cluster biosynthetic enzyme
Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides
Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
Transposase and inactivated derivatives, IS5 family
ABC-type proline/glycine betaine transport system, permease component
Methionine synthase I (cobalamin-dependent), methyltransferase domain
Zn-ribbon protein, possibly nucleic acid-binding
Efflux transporter, RND family, MFP subunit
ABC-type cobalt transport system, periplasmic component
Predicted enzyme related to lactoylglutathione lyase
Protein involved in response to biotic stimulus
Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after rbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
Selenocysteine synthase [seryl-tRNASer selenium transferase]
Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
Protein involved in DNA restriction-modification system
Transcriptional regulator, MerR family protein
Outer membrane receptor for Fe3+-dicitrate
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID
Uncharacterized protein with SCP/PR1 domains
Fis family transcriptional regulator protein
Predicted nucleotide-binding protein containing TIR -like domain
Transcriptional regulator, BadM/Rrf2 family protein
Predicted redox protein, regulator of disulfide bond formation
Glycine/Sarcosine/Betaine reductase complex protein A
Major facilitator superfamily MFS_1 protein
Urea amidohydrolase (urease) gamma subunit
Urea amidohydrolase (urease) beta subunit
Glutamate decarboxylase and related PLP-dependent proteins
Protein involved in positive regulation of transcription via sterol regulatory element binding
Protein; Evidence 5 : No homology to any previously reported sequences
Phosphosulfolactate phosphohydrolase and related enzymes
Predicted ATPase related to phosphate starvation-inducible protein PhoH
Adenylylsulfate kinase and related kinases
Short-chain alcohol dehydrogenase of unknown specificity
Predicted endonuclease containing a URI domain
Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
Prophage LambdaCh01, transcriptional regulator protein
Protein involved in innate immune response
Predicted phage phi-C31 gp36 major capsid-like protein
Phosphotransferase system, mannose/fructose-specific component IIA
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
Protein involved in peptidoglycan biosynthetic process
Protein found in conjugate transposon TraI
Ni,Fe-hydrogenase I cytochrome b subunit
Uncharacterized protein (competence- and mitomycin-induced)
CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes
Protein; crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is
Predicted thioesterase involved in non-ribosomal peptide biosynthesis
DNA methylase N-4/N-6 domain-containing protein
Peptidase C14 caspase catalytic subunit P20
Serine proteases of the peptidase family S9A
Kef-type K+ transport system, predicted NAD-binding component
Na+ driven multidrug efflux pump protein
Catalyzes the acylation of glycosyl-4,4'- diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12- methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains protein
Transcriptional regulator, AraC family protein
ABC-type glucose/galactose transport system, permease component
Phosphotransferase system, galactitol-specific IIB component
Protein involved in nucleotide catabolic process
Tram-Like protein found in conjugate transposon
Protein involved in unidirectional conjugation
Regulator of cell morphogenesis and NO signaling
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
Multisubunit Na+/H+ antiporter, MnhF subunit
Multisubunit Na+/H+ antiporter, MnhG subunit
Uncharacterized conserved protein containing a ferredoxin-like domain
Protein involved in muscarinic acetylcholine receptor signaling pathway
DNA-directed RNA polymerase, subunit K/omega
Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
H+-Transporting two-sector ATPase, E subunit
Phosphotransferase system, fructose-specific IIC component
Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
ABC-type proline/glycine betaine transport systems, periplasmic components
ABC-type proline/glycine betaine transport system, ATPase component
Highly conserved protein containing a thioredoxin domain
Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
Von Willebrand factor (vWF) type A domain-containing protein
ABC-type phosphate/phosphonate transport system, ATPase component
ABC-type phosphate/phosphonate transport system, periplasmic component
Uncharacterized protein involved in exopolysaccharide biosynthesis
Conserved domain frequently associated with peptide methionine sulfoxide reductase
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
Uncharacterized protein involved in methicillin resistance
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
Transcriptional regulator of a riboflavin/FAD biosynthetic operon
Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats
Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain
Dna-Directed RNA polymerase specialized sigma subunit, sigma24
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) protein
Antitoxin of toxin-antitoxin stability system
Uncharacterized membrane protein, required for colicin V production
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Phosphotransferase system cellobiose-specific component IIB
Phosphotransferase system cellobiose-specific component IIA
Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain
ABC-type enterochelin transport system, permease component
RTX toxins and related Ca2+-binding proteins
Heterodisulfide reductase, subunit A and related polyferredoxins
Predicted nucleic-acid-binding protein (contains the HHH domain)
DNA-directed RNA polymerase, delta subunit
Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
Type IV secretory pathway, TrbL components
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit
Protein-Conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
Sigma-K factor processing regulatory protein
Ribulose 1,5-bisphosphate carboxylase, large subunit
Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
Small primase-like proteins (Toprim domain)
DNA-binding transcriptional activator of the SARP family
N-methylhydantoinase B/acetone carboxylase, alpha subunit
N-methylhydantoinase A/acetone carboxylase, beta subunit
Protein involved in ribonucleotide reduction
Outer membrane lipoprotein-sorting protein-like protein
Predicted esterase of the alpha/beta hydrolase fold
Uncharacterized protein involved in tolerance to divalent cations
Phosphotransferase system fructose-specific component IIB
Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
Glycine reductase complex component B, alpha and beta subunits
Arsenite efflux pump ACR3 and related permeases
Sigma-K processing regulatory protein BofA
Allows the formation of correctly charged Asn-tRNA or Gln-tRNA through the transamidation of misacylated Asp- tRNA or Glu-tRNA in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA or phospho-Glu-tRNA
Zn-finger domain associated with topoisomerase type I
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
Type IV secretory pathway, VirB10 components
Type IV secretory pathway, TrbF components
XRE family transcriptional regulator protein
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Type II secretory pathway, component ExeA (predicted ATPase)
DNA polymerase, beta domain protein region
Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain
Predicted hydrocarbon binding protein (contains V4R domain)
Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
Protein involved in RNA-dependent DNA replication
Urea amidohydrolase (urease) alpha subunit
Radical S-adenosyl methionine domain containing protein
ATP-dependent protease HslVU (ClpYQ), ATPase subunit
Uncharacterized protein/domain associated with GTPases
Predicted hydrolase of the HD superfamily (permuted catalytic motifs)
Predicted transcriptional regulator, contains C-terminal CBS domains
Negative regulator of septation ring formation
Small nuclear ribonucleoprotein (snRNP) homolog
Uncharacterized protein conserved in archaea
Uncharacterized proteins of PilT N-term./Vapc superfamily
DNA polymerase elongation subunit (family B)
Arsenical resistance operon trans-acting repressor protein
Transcription initiation factor IIE, alpha subunit
Predicted prefoldin, molecular chaperone implicated in de novo protein folding
Tripartite ATP-independent periplasmic transporter DctQ protein
Predicted phosphoesterases, related to the Icc protein
Coenzyme F420-reducing hydrogenase, delta subunit
3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
Type II secretory pathway, pseudopilin PulG
Predicted phosphate-binding enzymes, TIM-barrel fold
Permease, similar to cation transporters
Uncharacterized homolog of PrgY (pheromone shutdown protein)
Energy-Converting hydrogenase B, subunit P
Uncharacterized domain/protein associated with RNAses G and E
Protein involved in polysaccharide transport
Uncharacterized enzyme of phosphonate metabolism
May act as a negative regulator of salt tolerance (By similarity) protein
Plasmid maintenance system killer protein
Uncharacterized protein involved in an early stage of isoprenoid biosynthesis
Predicted transcription factor, homolog of eukaryotic MBF1
ATP-dependent 26S proteasome regulatory subunit
Arginine degradation protein (predicted deacylase)
ABC-type Co2+ transport system, permease component
Polyketide synthase modules and related proteins
Membrane-bound lytic murein transglycosylase B
Phosphotransferase system sorbitol-specific component IIC
Phosphotransferase system sorbitol-specific component IIBC
ABC-type ribose transport system, auxiliary component
ABC-type phosphonate transport system, ATPase component
Metal-dependent hydrolase involved in phosphonate metabolism
Protein required for the initiation of cell division
Uncharacterized protein involved in propionate catabolism
Protein involved in cytochrome complex assembly
Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B
Protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase
Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain)
Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
Fibronectin type III domain containing 7 protein
Spindle assembly 6 homolog (C. elegans) protein
Protein involved in DNA catabolic process
Adenylate cyclase, class 2 (thermophilic)
Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
Predicted amino acid aldolase or racemase
RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)
Deacetylases, including yeast histone deacetylase and acetoin utilization protein
Transcriptional regulator, TetR family protein
Flp pilus assembly protein, secretin CpaC
Xylose isomerase domain protein TIM barrel
Transmembrane protein alanine and leucine rich
Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family
Sec-independent protein secretion pathway components
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
Signal transduction histidine kinase, glucose-6-phosphate specific
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE
30S ribosomal protein S21; a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
Predicted ATPases of PP-loop superfamily
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation , and thus conserves the redox energy in a proton gradient
Flavoprotein involved in thiazole biosynthesis
AAA ATPase containing von Willebrand factor type A (vWA) domain
Molybdopterin converting factor, small subunit
Uncharacterized protein involved in formation of curli polymers
Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain
Uncharacterized protein conserved in bacteria, putative lipoprotein
Predicted metal-binding protein related to the C-terminal domain of SecA
Uncharacterized protein involved in outer membrane biogenesis
Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases
Predicted RNA-binding protein (contains PUA domain)
Methyl coenzyme M reductase, beta subunit
Protein involved in protein O-linked glycosylation
Type II secretory pathway, component HofQ
ABC-type transport system involved in resistance to organic solvents, periplasmic component
Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase
Sulfite reductase, beta subunit (hemoprotein)
Catalyzes the attachment of tyrosine to tRNA in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA protein
CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)
CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)
Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
50S ribosomal protein L30; L30 binds domain II of the 23S rRNA and the 5S rRNA
M6 family metalloprotease domain protein
Uncharacterized proteins, homologs of lactam utilization protein B
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family
ABC-type uncharacterized transport system, duplicated ATPase component
Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
One of two assembly inititator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Signal transduction protein containing GAF and PtsI domains
Nitrate reductase cytochrome c-type subunit
Signal transduction histidine kinase, nitrate/nitrite-specific
Molybdopterin-guanine dinucleotide biosynthesis protein A
Pathogenesis-Related transcriptional factor and ERF
Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling
Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
ATP-dependent protease HslVU (ClpYQ), peptidase subunit
Palmitoyl transferase; catalyzes the transfer of palmitate to lipid A
Predicted transcription regulator containing HTH domain
Activator of Hsp90 ATPase 1 family protein
Uncharacterized protein involved in biosynthesis of c-type cytochromes
Cytochrome c-type biogenesis protein CcmE
ABC-type transport system involved in cytochrome c biogenesis, ATPase component
Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
ABC-type xylose transport system, permease component
Ethanolamine utilization protein, possible chaperonin
Predicted protease with the C-terminal PDZ domain
Racemase and epimerase, acting on amino acids and derivatives
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis protein
Function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the
Predicted hydrolase of the alpha/beta-hydrolase fold
ABC-type molybdate transport system, ATPase component
Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
Large low complexity protein with signal peptide, within large locus of signal peptide containing proteins
Cytochrome b subunit of formate dehydrogenase
Predicted lipoprotein involved in nitrous oxide reduction
Formate-dependent nitrite reductase, membrane component
Predicted periplasmic or secreted protein
Protein involved in cellular cell wall organization
Predicted TIM-barrel enzyme, possibly a dioxygenase
Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Membrane protein involved in colicin uptake
Protein involved in guanosine tetraphosphate metabolic process
Uncharacterized ABC-type transport system, ATPase component
Extracellular solute-binding protein family 1
ABC-type Zn2+ transport system, periplasmic component/surface adhesin
Outer membrane lipoprotein involved in outer membrane biogenesis
Outer membrane protein PgaA; outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS operon in Yersinia
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Additional sex combs like 3 (Drosophila) protein
Transport system, periplasmic component protein
Predicted RNA-binding protein containing a PIN domain
Glycosyl hydrolase family 32 domain protein
Protein involved in regulation of carbohydrate metabolic process
Protein involved in DNA mediated transformation
Flagellar motor switch/type III secretory pathway protein
Predicted Zn-ribbon RNA-binding protein with a function in translation
Predicted ATPase, RNase L inhibitor (RLI) homolog
N-acetylglutamate synthase and related acetyltransferases
DNA-directed RNA polymerase, subunit E''
Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain
Signal recognition particle 19 kDa protein
Uncharacterized protein conserved in bacteria, putative virulence factor
Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module
ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)
tRNA(1-methyladenosine) methyltransferase and related methyltransferases
Protein involved in glycine catabolic process
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
DNA-directed RNA polymerase, subunit N (RpoN/RPB10)
Coenzyme F420-reducing hydrogenase, gamma subunit
Queuine tRNA-ribosyltransferases, contain PUA domain
Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component
Predicted subunit of the Multisubunit Na+/H+ antiporter
ABC transporter membrane-spanning permease - amino acid transport
Molybdopterin converting factor, large subunit
Large family of predicted nucleotide-binding domains
Serine/threonine protein kinase involved in cell cycle control
Predicted DNA-binding protein containing a Zn-ribbon domain
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase
Predicted metal-dependent hydrolases with the TIM-barrel fold
Predicted RNA-binding protein containing a C-terminal EMAP domain
Uncharacterized protein related to Endonuclease III
Translation initiation factor 2, alpha subunit (eIF-2alpha)
Uncharacterized protein conserved in bacteria containing a pentein-type domain
Protein implicated in iron transport, frataxin homolog
Predicted ATPase involved in replication control, Cdc46/Mcm family
RNA-binding protein involved in rRNA processing
Choline dehydrogenase and related flavoproteins
Eukaryotic-type DNA primase, catalytic (small) subunit
Uncharacterized protein containing a Zn-ribbon
TATA-box binding protein (TBP), component of TFIID and TFIIIB
Predicted phosphotransferase related to Ser/Thr protein kinases
Methyl coenzyme M reductase, alpha subunit
Coenzyme F420-reducing hydrogenase, alpha subunit
Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline protein
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components
What is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif
Adenylate cyclase, family 3 (some proteins contain HAMP domain)
Protein involved in nucleoside metabolic process
Tetr family transcriptional regulator protein
3-hexulose-6-phosphate synthase and related proteins
Protein involved in protein secretion by the type II secretion system
Inhibitor of the KinA pathway to sporulation, predicted exonuclease
Uncharacterized protein with a bacterial SH3 domain homologue
Nucleolar and coiled-body phosphoprotein 1
Uncharacterized protein contain chitin-binding domain type 3
Phosphotransferase system sorbitol-specific component IIA
NMD protein affecting ribosome stability and mRNA decay
Cdc6-related protein, AAA superfamily ATPase
Acyl-Coa synthetase (AMP-forming)/AMP-acid ligase II-like protein
Uncharacterized enzyme of heme biosynthesis
Response regulator of citrate/malate metabolism
Predicted transcriptional regulator, BolA superfamily
Predicted NTP binding protein (contains STAS domain)
DNA recombination-dependent growth factor C
Predicted permease, cadmium resistance protein
Protein containing von Willebrand factor type A (vWA) domain
Phosphopantetheinyl transferase component of siderophore synthetase
Tellurite resistance protein and related permeases
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
Protein involved in nucleus localization
Uncharacterized enzyme involved in pigment biosynthesis
TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component
Phosphotransferase system, lactose/cellobiose-specific IIB subunit
GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport
CO dehydrogenase/acetyl-CoA synthase beta subunit
RNA polymerase factor sigma-70; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Positive regulator of sigma E, RseC/MucC protein
Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)
Membrane protein TerC, possibly involved in tellurium resistance
Transcriptional regulator, ArsR family protein
Periplasmic protein TonB, links inner and outer membranes
Protein involved in protein-heme linkage
Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system
Protein involved in sex pheromone biosynthesis
Twin-Arginine translocation protein, TatA/E family
Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
Involved in lipopolysaccharide biosynthesis protein
Mannitol/fructose-specific phosphotransferase system, IIA domain
Type IV secretory pathway, VirB2 components (pilins)
ABC-type Fe3+-citrate transport system, periplasmic component
Protein involved in regulation of conjugation
Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
Uncharacterized protein involved in chromosome partitioning
Transcriptional regulator of aromatic amino acids metabolism
Uncharacterized protein involved in response to NO
ABC-type arginine/histidine transport system, permease component
ABC-type arginine transport system, permease component
Type IV secretory pathway, component VirB8
Predicted aminomethyltransferase related to GcvT
Opacity protein and related surface antigens
Truncated, possibly inactive, lysyl-tRNA synthetase (class II)
ABC-type Co2+ transport system, periplasmic component
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
Cytochrome c nitrite reductase pentaheme subunit; part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia
Protein involved in negative regulation of cell division
Type II secretory pathway, component PulJ
Tfp pilus assembly protein, major pilin PilA
ABC-type thiamine transport system, periplasmic component
Predicted P-loop ATPase fused to an acetyltransferase
Type IV secretory pathway, VirB9 components
Uncharacterized enzymes related to aldose 1-epimerase
Uncharacterized protein involved in the oxidation of intracellular sulfur
Uncharacterized conserved protein involved in intracellular sulfur reduction
Uncharacterized membrane protein affecting hemolysin expression
ABC-type arginine transport system, ATPase component
ABC-type transport system involved in resistance to organic solvents, auxiliary component
Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gamma-aminobutyrate permease and related permeases
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
Protein involved in regulation of cellular response to stress
Uncharacterized C-terminal domain of topoisomerase IA
Uncharacterized protein, possibly involved in glyoxylate utilization
Secreted and surface protein containing fasciclin-like repeats
Coiled-Coil domain containing 110 protein
Cytochrome c-type biogenesis protein CcmB
Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme
Bacteriophage terminase large (ATPase) subunit and inactivated derivatives
Uncharacterized protein containing a NRPS condensation (elongation) domain
Collagen-binding surface adhesin SpaP (antigen I/II family)
Uncharacterized membrane protein, required for N-linked glycosylation
Predicted regulator of amino acid metabolism, contains ACT domain
Archaeal enzymes of ATP-grasp superfamily
Protein involved in barrier septum formation
Protein involved in electron transport chain
BioD-like N-terminal domain of phosphotransacetylase
Uncharacterized protein involved in formate dehydrogenase formation
Filamentation induced by cAMP protein Fic
ABC-type tungstate transport system, permease component
Uncharacterized component of anaerobic dehydrogenases
ABC-type taurine transport system, ATPase component
Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
Transcription factor homologous to NACalpha-BTF3
CO dehydrogenase/acetyl-CoA synthase alpha subunit
Predicted spermidine synthase with an N-terminal membrane domain
Predicted transcriptional regulator with C-terminal CBS domains
Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
NADH:ubiquinone oxidoreductase 27 kD subunit
Predicted RNA-binding protein of the translin family
Sulfhydryl-Activated toxin. Is able to lyse cholesterol containing membranes. Can be reversibly inactivated by oxidation. Cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes
Translation elongation factor EF-1alpha (GTPase)
Solute carrier family 18 (vesicular monoamine), member protein
DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS
Uncharacterized homolog of biotin synthetase
NADH:ubiquinone oxidoreductase 49 kD subunit 7
Predicted nucleic-acid-binding protein containing a Zn-ribbon
Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)
Signal transduction histidine kinase, nitrogen specific
Transcriptional regulator, ModE family protein
Excinuclease ABC C subunit domain protein
Predicted nucleotide kinase (related to CMP and AMP kinases)
Predicted metal-dependent hydrolase (urease superfamily)
Protein involved in cell differentiation
Uncharacterized protein involved in cysteine biosynthesis
Protein involved in mammary gland involution
Cellulose synthase regulator protein; binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid
Archaeal DNA polymerase II, large subunit
Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
Uncharacterized N-terminal domain of the transcription elongation factor GreA
Eukaryotic-type DNA primase, large subunit
Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB
Predicted transcriptional regulator with an HTH domain
DNA-directed RNA polymerase, subunit H, RpoH/RPB5
Methyl coenzyme M reductase, gamma subunit
Uncharacterized protein related to methyl coenzyme M reductase subunit C
Predicted RNA-binding protein (contains KH domains)
Activator of cell division through the inhibition of ftsZ GTPase activity, therefore promoting ftsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TRAP-type mannitol/chloroaromatic compound transport system, large permease component
Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
Protein implicated in ribosomal biogenesis, Nop56p homolog
Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)
Predicted archaeal kinase (sugar kinase superfamily)
Cytolysin, a secreted calcineurin-like phosphatase
Sulfur transfer protein involved in thiamine biosynthesis
TRAP-type mannitol/chloroaromatic compound transport system, small permease component
PUA domain (predicted RNA-binding domain)
Type III secretory pathway, component EscV
P pilus assembly protein, chaperone PapD
Type IV secretory pathway, protease TraF
Outer membrane receptor for monomeric catechols
Sulfite reductase, alpha subunit (flavoprotein)
ABC-type histidine transport system, ATPase component
DNA helicase TIP49, TBP-interacting protein
Glycoside hydrolase family 13 domain protein
Oxidoreductase, acting on the CH-CH group of donors
Maltoporin (phage lambda and maltose receptor)
Flp pilus assembly protein, protease CpaA
Reductase complex component C alpha subunit
Regulator of nitric oxide reductase transcription
PAP2 (acid phosphatase) superfamily protein
Permease for cytosine/purines uracil thiamine allantoin
Predicted enzyme of the cupin superfamily
Type III secretory pathway, lipoprotein EscJ
Type III secretory pathway, component EscR
50S ribosomal protein L33; in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc
Chaperone required for the assembly of the mitochondrial F1-ATPase
Type III secretory pathway, component EscS
Type III secretory pathway, component EscT
Type III secretory pathway, component EscU
Flagellar basal body P-ring biosynthesis protein
Uncharacterized ABC-type transport system, permease components
Endoglucanase C-terminal domain/subunit and related proteins
Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
Uncharacterized protein containing TOPRIM domain, potential nuclease
Uncharacterized protein related to proFAR isomerase (HisA)
Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain
Heptaprenyl diphosphate synthase component I
Predicted ATP-dependent carboligase related to biotin carboxylase
Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain
Acetolactate synthase (isozyme II), small (regulatory) subunit
Uncharacterized protein containing DHHC-type Zn finger
Cobalt ABC transporter, inner membrane subunit CbiQ
Protein involved in UDP-glucose metabolic process
Cas-Br-M (murine) ecotropic retroviral transforming sequence protein
Dissimilatory sulfite reductase (desulfoviridin), gamma subunit
Protein involved in transcription initiation from RNA polymerase II promoter
Protein involved in cell wall macromolecule catabolic process
Predicted ABC-type exoprotein transport system, permease component
Uncharacterized protein with an alpha/beta hydrolase fold
Acts as an activator of flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagellum
Monovalent cation/H+ antiporter subunit G; subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport
Anti-Sigma regulatory factor (serine/threonine protein kinase)
Zn-dependent alcohol dehydrogenases, class III
Signal transduction histidine kinase regulating C4-dicarboxylate transport system
Factor for inversion stimulation Fis, transcriptional activator
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit , connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites
Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
Protein involved in fungal-type cell wall organization or biogenesis
Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis
Uncharacterized protein affecting Mg2+/Co2+ transport
Protein involved in I-kappaB kinase/NF-kappaB cascade
Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A
Xanthine dehydrogenase, molybdopterin-binding subunit B
Identified by match to protein family HMM PF03886
Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis
Gcn5-Related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: mmp:MMP1184 N-acetyltransferase related protein
Predicted methyltransferase (contains TPR repeat)
Uncharacterized protein, probably involved in trehalose biosynthesis
Predicted ATPase/kinase involved in NAD metabolism
ABC-type tungstate transport system, periplasmic component
Flagellar assembly regulator FliX; regulator of the sigma 54 transcriptional activator FlbD; represses FlbD when the class II flagellar structure is absent and activates FlbD when the structure is present protein
Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase
Flagella basal body P-ring formation protein FlgA
Flagellar basal body-associated protein FliL
Uncharacterized protein, similar to the N-terminal domain of Lon protease
Integrin alpha FG-GAP repeat containing 2 protein
Enhanced serine sensitivity protein SseB; enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I
Glycine cleavage system regulatory protein
ABC-type siderophore export system, fused ATPase and permease components
Uncharacterized protein involved in formation of periplasmic nitrate reductase
Abc-Type nitrate/sulfonate/bicarbonate transporter, periplasmic ligand binding protein
Uncharacterized membrane protein required for alginate biosynthesis
Trans-Acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence
Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
ABC-type cobalamin transport system, permease component
ABC-type cobalamin transport system, ATPase component
Dna-Binding transcriptional activator OsmE; osmotically-inducible lipoprotein E; activator of ntr-like gene protein
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Putative salt-induced outer membrane protein
Uncharacterized protein/domain, possibly involved in tellurite resistance
Activator of osmoprotectant transporter ProP
Uncharacterized protein, homolog of Cu resistance protein CopC
Transcriptional activator FlhC; With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems protein
Transcriptional activator FlhD; with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems protein
Dual-Function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein fliD. As a transcriptional regulator, acts as an anti-flhDC factor; it directly binds flhC, thus inhibiting the binding of the flhC/flhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects fliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus
Colanic acid biosynthesis protein; WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid
Colanic acid biosynthesis protein; essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance
C-Lysozyme inhibitor; inactivates vertebrate C-type lysozyme protein
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing cell walls for activity protein
Uncharacterized protein involved in cation transport
ABC-type long-chain fatty acid transport system, fused permease and ATPase components
Heme/copper-type cytochrome/quinol oxidase, subunit 4
Heme/copper-type cytochrome/quinol oxidase, subunit 3
Heme/copper-type cytochrome/quinol oxidases, subunit 1
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
Interacts with the secY protein in vivo. May bind preferentially to an uncomplexed state of secY, thus functioning either as a chelating agent for excess secY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
Protein; in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Type II secretory pathway, component PulK
Type II secretory pathway, component PulC
Lipoprotein; induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS
Predicted periplasmic lipoprotein involved in iron transport
Uncharacterized protein involved in purine metabolism
Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane protein
Flagellar biosynthesis/type III secretory pathway chaperone
Negative regulator of flagellin synthesis (anti-sigma28 factor)
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
Membrane protein required for beta-lactamase induction
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
Uncharacterized component of phosphonate metabolism
Uncharacterized conserved protein involved in oxidation of intracellular sulfur
Protein involved in regulation of mitotic cell cycle
ABC-type hemin transport system, ATPase component
Uncharacterized conserved protein, contains FHA domain
Type II secretory pathway, component PulL
Protein affecting phage T7 exclusion by the F plasmid
Cell envelope opacity-associated protein A
Succinate dehydrogenase, hydrophobic anchor subunit
ABC-type Fe2+-enterobactin transport system, periplasmic component
ABC-type enterobactin transport system, permease component
Transcriptional regulator of met regulon
Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion
Required for the cell division process (By similarity) protein
Uncharacterized protein probably involved in high-affinity Fe2+ transport
Major membrane immunogen, membrane-anchored lipoprotein
Predicted ABC-type sugar transport system, permease component
Cutc family protein; identified by match to protein family HMM PF03932
Uncharacterized conserved small protein containing a coiled-coil domain
Transcription activator, effector binding protein
Predicted signal-transduction protein containing cAMP-binding and CBS domains
Bacteriophytochrome (light-regulated signal transduction histidine kinase)
Branched-Chain amino acid transport protein
Protein involved in double-strand break repair
Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase
SOS-response cell division inhibitor, blocks FtsZ ring formation
ABC-type protease/lipase transport system, ATPase and permease components
50S ribosomal protein L23; binds third domain of 23S rRNA and protein L29; part of exit tunnel
Protein involved in response to abiotic stimulus
Phosphonate C-P lyase system protein PhnG
RNA-binding protein required for 60S ribosomal subunit biogenesis
Uncharacterized conserved protein containing a coiled-coil domain
ABC-type thiamine transport system, ATPase component
Negative regulator of replication initiationR
Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) protein
Predicted signal transduction protein containing sensor and EAL domains
Dienelactone hydrolase and related enzymes
Universal stress protein UspB; ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
Phage shock protein B; acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding
Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
Uncharacterized relative of glutathione S-transferase, MAPEG superfamily
ABC-type hemin transport system, periplasmic component
Uncharacterized protein involved in benzoate metabolism
Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
Curli assembly protein CsgF; nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli ; part of the curli secretion and assembly protein complex
Heme/copper-type cytochrome/quinol oxidases, subunit 2
Polyprenyltransferase (cytochrome oxidase assembly factor)
Protein involved in histidine family amino acid biosynthetic process
Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
Tripartite ATP-independent periplasmic transporter DctQ component protein
Protein involved in proteasomal protein catabolic process
Atypical histidine kinase sensor of two-component system
Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives
ABC-type anion transport system, duplicated permease component
Antibiotic-Transport integral membrane leucine and alanine and valine rich protein ABC transporter
DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger)
BFD domain protein (2Fe-2S)-binding domain protein
Heat shock protein DnaJ domain-containing protein
Asnc family transcriptional regulator protein
Coiled-Coil domain containing 39 protein
Protein involved in respiratory electron transport chain
Ethyl tert-butyl ether degradation EthD protein
Membrane-Spanning 4-domains, subfamily A, member 14 protein
Predicted transmembrane transcriptional regulator (anti-sigma factor)
Spovt / AbrB like domain-containing protein
Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Type II secretory pathway, pseudopilin protein
Type IV secretory pathway, VirD4 protein
Uncharacterized membrane-bound protein conserved in bacteria
Putative exporter of polyketide antibiotics
Coiled-Coil domain containing 18 protein
Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family
MinD superfamily P-loop ATPase containing an inserted ferredoxin domain
Cro/Ci family transcriptional regulator protein
Holliday junction resolvase - archaeal type
Protein involved in Mo-molybdopterin cofactor metabolic process
Negative regulator of genetic competence protein
PTS system mannose/fructose/sorbose family IIA protein
Subunit R of type I restriction-modification system
Predicted transcriptional regulator containing CBS domains
Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
Predicted flavoprotein involved in K+ transport
Small subunit of phenylpropionate dioxygenase
Protein involved in antibiotic biosynthetic process
Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
Phosphoribosyl-Dephospho-Coa transferase; Catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein
Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
26S proteasome regulatory complex component
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core protein
Interacts with cbpA and inhibits both the dnaJ-like co- chaperone activity and the DNA binding activity of cbpA. Together with cbpA, modulates the activity of the dnaK chaperone system. Does not inhibit the co-chaperone activity of dnaJ protein
Phage shock protein G; coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia
Protein involved in peptidyl-histidine phosphorylation
Protein; COG: NOG04673 non supervised orthologous group; Psort location: cytoplasmic, score: 23
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases
Protein involved in potassium ion transport
Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels
Uncharacterized membrane-anchored protein conserved in bacteria
Protein involved in positive regulation of RNA elongation from RNA polymerase II promoter
NADH dehydrogenase (ubiquinone) 30 kDa subunit
Protein involved in integrin-mediated signaling pathway
Protein involved in negative regulation of protein secretion
Enoyl reductase domain of yeast-type FAS1
Part of a binding-protein-dependent transport system. responsible for the translocation of the substrate across the membrane (By similarity)
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Phosphatidic acid phosphatase type 2 domain containing
Predicted regulatory domain of a methyltransferase
Dissimilatory sulfite reductase subunit D
Na+/Solute symporter; PFAM: Na+/solute symporter; KEGG: hch:HCH_06692 Na+/proline symporter protein
Molybdopterin converting factor subunit 1
Protein involved in protein secretion by the type III secretion system
Ribulose-5-Phosphate 4-epimerase and related epimerase and aldolases
Predicted ATP-utilizing enzyme (ATP-grasp superfamily)
Tripartite ATP-independent periplasmic (TRAP) C4-dicarboxylate transporter subunit DctQ
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit
Outer membrane lipoprotein carrier protein
Splicing factor (branch point binding protein)
Identified by match to protein family HMM PF01266; match to protein family HMM PF01593
4-Amino-4-Deoxy-L-Arabinose transferase and related glycosyltransferase of PMT family-like
Arginine methyltransferase-interacting protein, contains RING Zn-finger
RIO-like serine/threonine protein kinase fused to N-terminal HTH domain
Electron transfer flavoprotein (beta subunit)
Thiamine biosynthesis protein ThiC; required for the synthesis of the hydromethylpyrimidine moiety of thiamine
Protein; identified by match to protein family HMM PF07811
Protein involved in gene silencing by RNA
Protein involved in nervous system development
Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit
N-terminal domain of the phosphotransferase system fructose-specific component IIB