ORF name SGD name Neural network output Fourier score in list of Known genes in list of Zhao genes in list of Spellman genes in list of Cho genes SGD Gene Description
YIL169C 0.98 2.8 C
YNL322C KRE1 0.98 1.7 cell wall beta-glucan assembly
YJL078C PRY3 0.98 5.5 S C "Pathogen Related in Sc, contains homology to the plant PR-1 class of pathogen related proteins. The protein sequence is over 60% identical with the Pry2p & Pry3p over 145 resid. PRY1 is >35% identical (50% similar) to tobacco PR-1c protein."
YOR009W TIR4 0.98 1.0
YDL038C 0.98 5.3
YOL155C 0.97 3.0 C
YJR151C DAN4 0.97 1.3 Delayed Anaerobic Gene
YOL030W GAS5 0.97 4.1 Z S Hypothetical ORF
YLR286C CTS1 0.97 9.3 K S C Endochitinase
YOR220W 0.97 2.5
YNR044W AGA1 0.97 6.5 K S anchorage subunit of a-agglutinin
YGR023W MTL1 0.97 1.8 Mid-Two Like 1
YMR317W 0.97 2.1
YCR089W FIG2 0.97 3.4 "Factor-Induced Gene 2: expression is induced by the mating pheromones, a and alpha factor; required for efficient mating"
YLR194C 0.96 5.4 S
YIL011W TIR3 0.96 2.6 S TIP1-related
YGR161C 0.96 2.4
YBR067C TIP1 0.96 5.9 K Z S C cold- and heat-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins
YNL327W EGT2 0.96 8.7 K S "cell-cycle regulation protein, may be involved in the correct timing of cell separation after cytokinesis"
YLR332W MID2 0.96 1.5 Protein required for mating
YNR067C DSE4 0.96 6.3 S C Daughter Specific Expression 4
YOR382W FIT2 0.96 1.8 "FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors."
YLR390W-A CCW14 0.96 2.7 Secretory Stress Response protein
YHR143W DSE2 0.96 7.3 S Daugher Specific Expression 2
YFR054C 0.96 1.6
YDL211C 0.96 3.3 S
YLR353W BUD8 0.96 4.2 Z S C marks and directs bud emergence to the distal pole of diploid cells
YNL283C WSC2 0.95 5.8 Z S cell wall integrity and stress response component 2
YDR349C YPS7 0.95 1.4 Gpi-anchored aspartic protease (Yapsin 7)
YHR212C 0.95 0.8
YOL105C WSC3 0.95 1.2 cell wall integrity and stress response component 3
YIL117C PRM5 0.95 3.7 S pheromone-regulated membrane protein
YDR534C FIT1 0.95 1.5 "FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors."
YIR016W 0.95 0.8
YDR055W PST1 0.95 5.5 S Protoplasts-secreted
YLR120C YPS1 0.95 1.8 Gpi-anchored aspartic protease (Yapsin 1)
YGL028C SCW11 0.95 8.2 S C Soluble Cell Wall protein
YDR451C YHP1 0.95 5.3 S C
YJL158C CIS3 0.94 4.7 S cik1 suppressor
YJR004C SAG1 0.94 3.8 S alpha-agglutinin
YNL176C 0.94 3.7 Z S C
YGL035C MIG1 0.94 1.1 Transcription factor involved in glucose repression
YOR383C FIT3 0.94 2.0 S "FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors."
YMR307W GAS1 0.94 5.6 K S Glycophospholipid-anchored surface protein
YDL136W RPL35B 0.94 2.3 Homology to rat L35
YDL191W RPL35A 0.94 2.0 Homology to rat L35
YMR233W TRI1 0.94 0.8 Topoisomerase 1 and RAD52 epistasis group Interactions
YBR130C SHE3 0.94 1.9 Z cytoplasmic protein involved in mother-specific HO expression
YOR279C RFM1 0.94 0.8 Repression Factor of MSE
YNL074C MLF3 0.94 0.8 Protein of unknown function
YLR121C YPS3 0.94 5.5 S C Gpi-anchored aspartic protease (Yapsin 3)
YGL056C SDS23 0.94 1.0 homolog of pombe SDS23; localizes to spindle pole body
YEL040W UTR2 0.93 2.7 S (alias: Congo Red Hypersensitivity)
YOR247W SRL1 0.93 4.8 S Suppressor of Rad53 null Lethality
YER028C 0.93 1.8
YNL053W MSG5 0.93 2.5 C Tyrosine protein phosphatase involved in adaptation response to pheromone
YGL032C AGA2 0.93 4.1 S adhesion subunit of a-agglutinin
YOR010C TIR2 0.93 1.6 cold-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins
YDR439W LRS4 0.93 1.2 Loss of rDNA silencing
YKR092C SRP40 0.93 1.9 Suppressor of mutant AC40 subunit of RNA polymerase I and III (high serine)
YLR457C NBP1 0.93 2.9 S C Nap1p Binding Protein
YJL053W PEP8 0.93 1.0 Plays a role in delivery of proteins to the vacuole
YGL003C CDH1 0.93 1.5 CDC20 homolog 1
YNL042W BOP3 0.92 2.3 bypass of PAM1
YLR040C 0.92 2.6 S
YHR214W 0.92 2.3
YAR066W 0.92 1.7
YIL123W SIM1 0.92 6.0 Z S (putative) invovled in control of DNA replication
YFR022W 0.92 2.2
YPL014W 0.92 3.5 S C
YPR171W 0.92 1.1
YOR233W KIN4 0.92 2.1 protein kinase
YPL155C KIP2 0.92 3.3 Z S kinesin-related protein
YML041C VPS71 0.92 0.9
YKL079W SMY1 0.92 2.0 "not believed to act as a kinesin, colocalizes with Myo2p"
YGR035C 0.92 4.5 S C
YJR150C DAN1 0.92 2.6 Delayed Anaerobic
YNR014W 0.92 1.8
YLR394W CST9 0.92 1.5 Chromosome STability; involved in meiotic chromosome synapsis
YIR019C MUC1 0.92 1.5 Required for invasion and pseudohyphae formation in response to nitrogen starvation
YLR265C NEJ1 0.92 0.9 Nonhomologous End-Joining regulator 1; Repressed by MAT heterozygosity; Interacts with Lif1p in a yeast two-hybrid assay
YKR102W FLO10 0.92 1.9 Protein with similarity to flocculation protein Flo1p
YDR447C RPS17B 0.92 1.3 Homology to rat ribosomal protein S17
YLR042C 0.91 1.6
YKR091W SRL3 0.91 3.0 S Suppressor of Rad53 null Lethality
YNL078W NIS1 0.91 5.3 S C
YDR420W HKR1 0.91 1.3 cell surface protein that may regulate cell wall beta-glucan synthesis and bud site selection; Hanenula mrakii killer toxin-resistance protein
YGL162W SUT1 0.91 3.0 S Involved in sterol uptake
YOR019W 0.91 0.8
YKR010C TOF2 0.91 4.2 Z S C topoisomerase I interacting factor 2
YBR162C TOS1 0.91 2.6 Target of SBF
YDL129W 0.91 1.6
YGR074W SMD1 0.91 1.7 "Homolog of human core snRNP protein D1, involved in snRNA maturation"
YMR188C 0.91 2.1
YMR268C PRP24 0.91 1.1 U4/U6 snRNA-associated splicing factor
YGL259W YPS5 0.91 2.4 Gpi-anchored aspartic protease (Yapsin 5)
YGR091W PRP31 0.90 0.9 pre-mRNA splicing protein
YGR014W MSB2 0.90 3.7 Z S putative integral membrane protein
YER011W TIR1 0.90 2.4 K Cold-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins. Encodes a stress-response cell wall mannoprotein and this gene is downregulated at acidic pH.
YAL065C 0.90 2.0
YBR203W 0.90 1.7
YOR372C NDD1 0.90 2.8 Z S Nuclear Division Defective 1
YCL063W 0.90 4.1 S C
YOL036W 0.90 1.0
YGR279C SCW4 0.90 4.2 S C Soluble Cell Wall protein
YLR313C SPH1 0.90 5.9 Z S C SPa2-Homolog; protein involved in shmoo formation and required for bipolar bud site selection (GB:AF008236).
YDR277C MTH1 0.90 1.6 C Negative regulator of HXT gene expression
YDR169C STB3 0.90 1.7 binds Sin3p in two-hybrid assay
YDL028C MPS1 0.90 1.8 Required for spindle pole body duplication and a mitotic checkpoint function.
YHR004C NEM1 0.90 0.8 Nuclear Envelope Morphology
YDR223W 0.90 1.0
YOR324C 0.90 3.3 S
YHR211W FLO5 0.90 0.8 FLO5- and FLO8-determined flocculation are considerably less sensitive to mannose than FLO1-determined flocculation.
YLR094C GIS3 0.90 1.6 GIG3 suppressor
YOL060C MAM3 0.90 1.4 putative hemolysin-like protein with three transmembrane domains
YDL194W SNF3 0.90 1.3 glucose sensor
YJR115W 0.90 0.8
YML109W ZDS2 0.90 2.7 S C multicopy suppressor of a sin4 defect
YDR077W SED1 0.90 3.7 K S putative cell surface glycoprotein
YDR200C VPS64 0.90 1.7
YDR144C MKC7 0.89 2.0 S protease involved in protein processing that shares functions with Yap3 and Kex2
YDR507C GIN4 0.89 4.5 S C Growth inhibitory gene
YBR215W HPC2 0.89 1.1 Protein required for normal cell-cycle regulation of histone gene transcription
YJL160C 0.89 2.0
YOR023C AHC1 0.89 1.7 S Ada Histone acetyltransferase complex component
YDL127W PCL2 0.89 6.6 K Z S C Interacts with cyclin-dependent kinase PHO85 to form kinase complex with G1-periodic activity involved in cell cycle progression
YKL006C-A SFT1 0.89 1.1 Required for transport of proteins between an early and a later golgi compartment. possible NSF attachment protein receptor (V-SNARE)
YOR058C ASE1 0.89 4.5 K Z S C essential for anaphase spindle elongation
YGR079W 0.89 1.1
YJL128C PBS2 0.89 1.1 "Involved in osmoregulation, member of the HOG1 mitogen-activated protein kinase (MAPK) cascade"
YDL048C STP4 0.89 3.3 S C Involved in pre-tRNA splicing and in uptake of branched-chain amino acids
YDR524C AGE1 0.89 1.1 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector
YDR379W RGA2 0.89 1.6 "contains a Rho-GAP domain and two LIM domains, similar to Rga1p and all known Rho-GAPs"
YPL070W 0.89 1.1
YBR156C SLI15 0.89 1.9 C Mitotic spindle protein involved in chromosome segregation.
YDL197C ASF2 0.89 4.1 K Z S C anti-silencing protein that causes depression of silent loci when overexpressed
YOR288C MPD1 0.89 2.0 Disulfide isomerase related protein
YPR023C EAF3 0.89 1.3 Esa1p-Associated Factor
YDR422C SIP1 0.89 1.2 SNF1 protein kinase substrate
YBR214W SDS24 0.89 1.8 "Similar to S. pombe SDS23, suppresses DIS2, localized to the nucleus"
YHR096C HXT5 0.89 2.3 Member of superfamily of monosaccharide transporters
YDR528W HLR1 0.89 4.5 Z S LRE1 homolog
YOR014W RTS1 0.89 1.1 B-type regulatory subunit of protein phosphatase 2A (PP2A)
YOR008C SLG1 0.89 1.3 cell wall integrity and stress response component 1
YPR075C OPY2 0.88 3.4 S imparts Far- phenotype
YOL070C 0.88 3.4 S C
YKL175W ZRT3 0.88 1.8
YBR142W MAK5 0.88 1.7 Necessary for maintenance of dsRNA killer plasmids. Is predicted to encode an DEAD-box RNA helicase
YPR083W MDM36 0.88 1.6 Mitochondrial Distribution and Morphology
YGL113W SLD3 0.88 0.9 synthetic lethality with dpb11-1; Sld3p interacts with Cdc45 and is required for initiation of DNA replication.
YNR039C ZRG17 0.88 1.0 zinc-regulated gene
YNL096C RPS7B 0.88 0.9 Homology to human S7 and Xenopus S8
YIL015W BAR1 0.88 1.1 extracellular protease synthesized in a-cells that cleaves and inactivates alpha factor
YGL209W MIG2 0.88 2.8 S "Involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter"
YKR045C 0.88 1.0
YBR119W MUD1 0.88 1.1 U1 snRNP A protein
YDL037C 0.88 8.3 S
YOL091W SPO21 0.88 2.0 sporulation defective
YLL021W SPA2 0.88 2.3 C spindle pole antigen
YDR309C GIC2 0.88 4.2 K S C Gtpase-interacting component 2
YBR255W 0.88 1.3
YGR027C RPS25A 0.88 0.9 Homology to rat S25
YDR436W PPZ2 0.88 1.6 serine-threonine phosphatase Z
YLR003C 0.88 1.4
YNL272C SEC2 0.88 2.1 C Protein with coiled-coil domain essential for vesicular transport
YLL038C ENT4 0.88 1.5 epsin N-terminal homology-containing protein
YBL031W SHE1 0.88 2.1 Product of gene unknown
YPR056W TFB4 0.88 1.3 "RNA polymerase transcription initiation TFIIH (factor b), 37 kDa subunit"
YJR021C REC107 0.88 1.2 meiotic recombination protein
YHR049C-A 0.88 1.1
YOL012C HTZ1 0.88 3.5 Z S C Histone-related protein that can suppress histone H4 point mutation
YOR018W ROD1 0.88 3.2 Z S "Resistance to o-dinitrobenzene, calcium, and zinc"
YGL171W ROK1 0.88 1.1 contains domains found in the DEAD protein family of ATP-dependent RNA helicases; high-copy suppressor of kem1 null mutant
YDR227W SIR4 0.87 1.4 "Sir4 binding to Rap1 initiates the sequential association of Sir and other proteins, allowing the subsequent spreading of heterochromatin proteins along the chromosome."
YOR355W GDS1 0.87 2.3 S involved in nuclear control of mitochondria
YOR295W UAF30 0.87 1.0 Topoisomerase 1 and RAD52 epistasis group Interactions
YLR031W 0.87 1.4
YPL158C 0.87 6.1 S C
YPL039W 0.87 0.9
YLR333C RPS25B 0.87 1.3 Homology to rat S25; belongs to the S25E family of ribosomal proteins
YGR068C 0.87 1.7
YKL176C LST4 0.87 1.1 required for amino acid permease transport from the Golgi to the cell surface. involved in regulated secretion/recycling of nitrogen regulated permeases.
YNL269W 0.87 2.1
YKR019C IRS4 0.87 1.0 Increased rDNA silencing
YLR035C MLH2 0.87 1.6 Mutl Homolog
YKL108W SLD2 0.87 5.4 Z S C Synthetically lethal with dpb11-1; required for DNA replication
YDL239C ADY3 0.87 2.7 Accumulation of dyads
YHL031C GOS1 0.87 1.3 SNARE protein with a C-terminal membrane anchor
GOlgi Snare
YPL074W YTA6 0.87 2.4 Member of CDC48/PAS1/SEC18 family of ATPases
YDL074C BRE1 0.87 1.3 putative coiled-coil protein with RING-finger and myosin-like domains
YCR067C SED4 0.87 1.2 "Sed4p is an integral ER membrane protein, which, along along with its close homolog, Sec12p, is involved in vesicle formation at the ER"
YKL198C PTK1 0.87 0.9 Putative serine/threonine protein kinase
YAL041W CDC24 0.87 1.2 calcium-binding protein involved in bud emergence and schmooing
YJL051W 0.87 6.1 Z S C
YDR285W ZIP1 0.87 2.0 "Synaptonemal complex protein, component of the central element"
YGR166W KRE11 0.87 1.1 Involved in biosynthetic pathway for cell wall beta-glucans
YKR005C 0.87 1.6
YNL002C RLP7 0.87 1.6 "Significant sequence similarity to RPL7B, but neither can functionally replace the other. Does not correspond to any ribosomal component identified so far, based on its biochemical features"
YOR359W VTS1 0.87 1.1 vti1-2 suppressor
YPL066W 0.87 1.4 C
YMR081C ISF1 0.87 1.2 "May regulate NAM7 function, possibly at level of mRNA turnover"
YDR116C 0.87 1.7
YCR048W ARE1 0.87 1.9 Acyl-CoA cholesterol acyltransferase (sterol-ester synthetase)
YOL100W PKH2 0.87 1.9 Pkb-activating Kinase Homologue
YDL179W PCL9 0.86 1.9 K S C PHO85 cyclin
YER064C 0.86 1.9
YKL011C CCE1 0.86 1.8 cruciform cutting endonuclease
YJL215C 0.86 2.6
YLR409C UTP21 0.86 1.1 Protein required for cell viability
YAL028W 0.86 2.1
YGR283C 0.86 1.3
YPR065W ROX1 0.86 1.8 The ROX1 gene encodes a heme-induced repressor of hypoxic genes in yeast.
YKL065C YET1 0.86 2.1 S Yeast homolog of human BAP31 protein
YHR188C GPI16 0.86 1.7 Glycosyl Phosphatidyl Inositol 16
YNL233W BNI4 0.86 4.6 Z S C bud neck involved
YDR544C 0.86 1.9
YOL001W PHO80 0.86 1.0 Negative regulator of PHO81 and PHO5
YMR305C SCW10 0.86 4.9 S Soluble Cell Wall protein
YNL234W 0.86 1.1
YKL064W MNR2 0.86 1.1 Product of gene unknown
YOR264W DSE3 0.86 2.6 S C Daughter Specific Expression 3
YOR353C SOG2 0.86 1.3 Protein required for cell viability
YCR030C SYP1 0.86 1.7 Suppressor of Yeast Profilin deletion
YDL105W QRI2 0.86 2.9 S C Product of gene unknown
YBR065C ECM2 0.86 0.9 C ExtraCellular Mutant
YGL046W 0.86 1.2
YJR134C SGM1 0.86 1.7 involved in carbohydrate metabolism
YCL027W FUS1 0.86 3.9 K S cell-surface protein required for cell fusion
YLR319C BUD6 0.86 1.0 actin interacting rotein
YGL134W PCL10 0.86 1.8 PHO85 cyclin
YJL076W NET1 0.86 1.8 Nucleolar protein involved in exit from mitosis
YER114C BOI2 0.86 1.9 "Protein which binds Bem1p and contains a proline-rich sequence, an SH3 domain, and a pleckstrin homology domain"
YIL016W SNL1 0.86 0.9 Suppressor of nup116-C lethal. Snl1p is the first Bag domain protein identified in S. cerevisiae.
YBL054W 0.86 1.8
YOR050C 0.86 1.8
YKR044W UIP5 0.86 1.8 Ulp1 Interacting Protein 5
YIL147C SLN1 0.86 1.0 Synthetic lethal of N-end rule
YDR194C MSS116 0.85 1.8 Mitochondrial RNA helicase of the DEAD box family
YDR130C FIN1 0.85 3.5 S Cell cycle-dependent filament between nuclei
YBL009W 0.85 3.6 Z S
YKL049C CSE4 0.85 2.2 C Required for proper kinetochore function; may be involved in assembly of a CEN-specific chromatin structure
YDR184C ATC1 0.85 0.9 "interacts with AIP3, localized to the nucleus"
YMR291W 0.85 2.4
YOL108C INO4 0.85 1.3 Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis
YBR102C EXO84 0.85 0.9 exocyst complex component; homolog in rat brain called rExo84.
pre-mRNA splicing factor.
YOR198C BFR1 0.85 1.1 Multicopy suppressor of BFA (Brefeldin A)-induced lethality; implicated in secretion and nuclear segregation
YPR141C KAR3 0.85 3.6 K S C kinesin-like nuclear fusion protein
YER129W PAK1 0.85 0.9 high copy suppressor of temperature sensitive cdc17 (DNA polymerase alpha) mutations
YIL146C ECM37 0.85 1.1 ExtraCellular Mutant
YNL183C NPR1 0.85 1.2 Stablizes several nutrient transporters by antagonizing a ubiquitin-mediated protein degradation pathway.
YPL137C 0.85 1.6
YBR250W 0.85 1.0
YPL202C AFT2 0.85 1.3 Activator of Iron (Fe) Transcription
YPL081W RPS9A 0.85 1.0 Homology to rat S9 and E.coli S4
YDR464W SPP41 0.85 1.3 C appears to control expression of spliceosome components PRP4 and PRP3
YGL081W 0.85 1.0
YDR363W ESC2 0.85 1.7 Establishes Silent Chromatin
YDR386W MUS81 0.85 1.6 Mms and UV Sensitive; Mus81p and Rad54p are found together in a complex from whole-cell extracts
YDR243C PRP28 0.85 1.5 Required for the first step of splicing in vitro
YBR260C RGD1 0.85 1.0 Related GAP Domain
YBR189W RPS9B 0.85 2.1 Homology to rat S9 and E. coli S4
YMR019W STB4 0.85 1.2 binds Sin3p in two-hybrid assay
YNL267W PIK1 0.85 0.9 "catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokineses through the actin cytoskeleton"
YJL103C 0.85 1.7 C
YGR272C 0.85 1.2
YIL056W 0.85 2.9 Z S
YBR078W ECM33 0.85 3.2 ExtraCellular Mutant
YPR015C 0.85 2.1
YPL269W KAR9 0.85 3.4 S cortical protein required for cytoplasmic microtubule orientation; localizes to the tip of shmoo projections and to the tip of budding cells in a cell-cycle dependent manner
YNL197C WHI3 0.84 4.2 Z S Protein involved in regulation of cell size
YER040W GLN3 0.84 0.9 Regulates glutamine-repressible gene products
YPR095C SYT1 0.84 0.8 Suppressor of Ypt3
YMR153W NUP53 0.84 1.0 Component of karyopherin docking complex of the nuclear pore complex
YOR227W 0.84 2.1
YGR113W DAM1 0.84 2.9 S Duo1 And Mps1 interacting. Localized to intranuclear spindles and spindle pole bodies.
YDR103W STE5 0.84 1.0 Protein of the pheromone pathway
YPR115W 0.84 1.1
YDR304C CPR5 0.84 1.2 "Cyclophilin D, Peptidyl-prolyl cis-trans isomerase D"
YHR103W SBE22 0.84 1.3 functionally redundant and similar in structure to SBE2
YDR295C PLO2 0.84 0.9 Ploidy-related. Shares homology with PLO1
YGR225W AMA1 0.84 1.0 "Required for sporulation, highly induced during sporulation; activator of meiotic anaphase promoting complex"
YPR124W CTR1 0.84 2.7 "High affinity copper transporter into the cell, probable integral membrane protein"
YLR325C RPL38 0.84 1.3 Homology to rat L38
YDR216W ADR1 0.84 1.3 Positive transcriptional regulator of ADH2 and peroxisomal protein genes
YLR453C RIF2 0.84 1.2 Rap1p-Interacting Factor 2; interacts with the c-terminus of Rap1p and with Rif1p; has functional similarities with Rif1p; Rif2p and Rif1p have synergistic effects on telomere length and chromosome loss
YGR237C 0.84 1.6
YDR370C 0.84 1.0
YHR094C HXT1 0.84 1.9 S High-affinity hexose (glucose) transporter
YGL143C MRF1 0.84 1.1 Mitochondrial polypeptide chain release factor
YKR037C SPC34 0.84 2.7 S Spindle Pole Component of molecular weight 34 kDa
YMR102C 0.84 1.7
YKL020C SPT23 0.84 1.0 Dosage dependent suppressor of Ty-induced promoter mutations. Homolog of Mga2. Spt23p and Mga2p differentially activate and regulate OLE1 transcription.
YBR200W BEM1 0.84 3.4 Z S C "SH3-domain protein that binds Cdc24p, Ste5p and Ste20p, and the Rsr1p/Bud2p/Bup5p GTPase"
YOR096W RPS7A 0.84 1.9 Homology to human S7 and Xenopus S8
YKR071C DRE2 0.84 1.1 Protein required for cell viability
YFR021W AUT10 0.84 1.3 Required for cytoplasm to vacuole targeting of proaminopeptidase I and starvation induced autophagy (AUT10). Needed for pre-Meiotic Replication (NMR1).
YBL090W MRP21 0.84 1.6 Mitochondrial Ribosomal Protein
YJL028W 0.84 2.8
YNL192W CHS1 0.84 2.8 K S disrupts mating and sporulation efficiently
YJL084C 0.84 2.4
YLR436C ECM30 0.84 1.2 ExtraCellular Mutant
YEL062W NPR2 0.84 1.5 Putative post-transcriptional regulator of nitrogen permeases
YHR159W 0.84 3.0 S
YMR068W AVO2 0.84 1.1 Adheres VOraciously (to TOR2)
YDR345C HXT3 0.84 1.8 Low-affinity glucose transporter
YIL092W 0.84 1.2
YNL012W SPO1 0.84 1.0 "dispensable for mitosis, premeiotic DNA synthesis, synaptonemal complexes, and recombination, but required for meiotic spindle pole body duplication/separation, meiosis I, meiosis II, and spore formation"
YMR148W 0.84 1.9 C
YDR219C 0.84 2.7 C
YDR306C 0.83 0.8
YOR223W 0.83 0.9
YBR193C MED8 0.83 1.1 Member of RNA Polymerase II transcriptional regulation mediator
YLR225C 0.83 2.3 S
YDL133W 0.83 1.1
YOL113W SKM1 0.83 2.5 Serine/threonine protein kinase with similarity to Ste20p and Cla4p
YPL115C BEM3 0.83 1.0 Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42
YPL253C VIK1 0.83 3.1 Z S vegetative interaction with Kar3p
YFL026W STE2 0.83 3.4 K S alpha-factor pheromone receptor; seven-transmembrane domain protein
YAL040C CLN3 0.83 3.8 K S C role in cell cycle START; involved in G(sub)1 size control
YLR072W 0.83 1.6
YOL130W ALR1 0.83 0.8 aluminium resistance
YLR082C SRL2 0.83 1.4 Suppressor of Rad53 null Lethality
YKL050C 0.83 1.9
YFR034C PHO4 0.83 2.3 Z Transcription factor that activates expression of phosphate pathway
YBL101C ECM21 0.83 1.8 ExtraCellular Mutant
YLR045C STU2 0.83 4.3 Z S C "May play a role in attachment, organization, and/or dynamics of microtubule ends at the spindle pole body"
YLR096W KIN2 0.83 1.4 Serine/threonine protein kinase
YJL063C MRPL8 0.83 1.6 Mitochondrial ribosomal protein MRPL8 (YmL8) (E. coli L17)
YDR255C RMD5 0.83 1.7 Required for Meiotic nuclear Division
YKL179C COY1 0.83 1.4 CASP Of Yeast
YOR273C TPO4 0.83 4.3 S C Polyamine transport protein
YLR312C 0.83 2.0
YDR393W SHE9 0.83 0.8 Mrna (identified by a library screen) that causes growth arrest when overexpressed.
Mitochondrial Distribution and Morphology
YBR158W CST13 0.83 6.0 S C Chromosome STability
YBR141C 0.83 0.8
YNL248C RPA49 0.83 1.1 49-kDa alpha subunit of RNA polymerase A
YGL200C EMP24 0.83 2.7 S C "type I transmembrane protein, component of COPII-coated, ER-derived transport vesicles"
YLL059C 0.83 2.5
YJL110C GZF3 0.83 1.2 Dal80 homolog
YDR351W SBE2 0.83 1.0 Required for bud growth
YHL007C STE20 0.83 0.9 Involved in pheromone response and pseudohyphal growth pathways
YGL007W 0.83 1.6
YCR061W 0.83 1.1
YBL102W SFT2 0.83 1.4 similar to mammalian syntaxin 5
YDR072C IPT1 0.83 1.8 necessary for synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C)
YHR139C SPS100 0.83 2.9 involved in spore development
YER006W NUG1 0.83 1.4 NUclear GTPase
YBL085W BOI1 0.83 1.4 Involved in bud growth
YOR071C 0.82 1.4
YBR014C 0.82 1.0
YJL116C NCA3 0.82 3.3 "With NCA2, regulates proper expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase"
YPL124W SPC29 0.82 3.7 Z S C spindle pole body component
YHR052W CIC1 0.82 0.8 Core interacting component 1
YHL023C RMD11 0.82 0.8 Required for Meiotic nuclear Division
YJL156C SSY5 0.82 1.1 Product of gene unknown
YOR154W 0.82 1.3
YOR322C 0.82 1.1
YJL122W 0.82 1.5
YGR070W ROM1 0.82 2.0 Gdp-GTP Exchange Protein (GEP) for the Rho1p Small GTP-binding Protein
YHR131C 0.82 0.9
YJR092W BUD4 0.82 5.3 S C co-assembles with Bud3p at bud sites
YGL179C 0.82 2.2
YJL057C IKS1 0.82 1.2 ira1* kinase suppressor
YER047C SAP1 0.82 1.8 interacts with Sin1p
YLL010C PSR1 0.82 1.7 Plasma membrane Sodium Response 1
YPL141C 0.82 5.0 S
YKR067W GPT2 0.82 1.4 Encodes a Glycerol-3-phosphate acyltransferase
YEL067C 0.82 1.3
YKR089C 0.82 1.1
YOR044W 0.82 1.0
YNL046W 0.82 1.8 S C
YHR066W SSF1 0.82 1.4 putative involvement in mating
YHL048W COS8 0.82 1.4 "Protein with similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YDR274C 0.82 3.5
YJR098C 0.82 1.2
YDR247W 0.82 4.1 S
YOL061W PRS5 0.82 1.3 Phosphoribosylpyrophosphate synthetase (ribose-phosphate pyrophosphokinase)
YJL092W HPR5 0.82 3.8 K Z S C Required for proper timing of committment to meiotic recombination and the transition from Meiosis I to Meiosis II
YJL079C PRY1 0.82 7.0 S C "Pathogen Related in Sc, contains homology to the plant PR-1 class of pathogen related proteins. The protein sequence is over 60% identical with the Pry2p & Pry3p over 145 resid. PRY1 is >35% identical (50% similar) to tobacco PR-1c protein."
YDL089W 0.82 2.2 S
YGL090W LIF1 0.82 2.9 S Ligase Interacting Factor 1; physically interacts with DNA ligase 4 protein (Lig4p)
YJR054W 0.82 2.7 S
YDR217C RAD9 0.81 1.3 "Required for DNA damage-induced G2 arrest in mitosis, required for ionizing radation-induced G1 arrest, and other cdc13-induced G2 arrest in meiosis"
YOR192C 0.81 2.0
YEL061C CIN8 0.81 3.7 Z S C Kinesin-related protein involved in establishment and maintenance of mitotic spindle
YMR005W TAF4 0.81 1.7 Protein required for protein synthesis
YIL095W PRK1 0.81 1.0 p53 regulatory kinase
YPL128C TBF1 0.81 3.6 S TTAGGG repeat binding factor
YGL197W MDS3 0.81 2.1 Mck1 Dosage Suppressor 3; negative regulator of early meiotic gene expression
YER059W PCL6 0.81 1.7 PHO85 cyclin
YNL301C RPL18B 0.81 1.4 Homology to rat ribosomal protein L18
YOL120C RPL18A 0.81 1.3 Homology to rat ribosomal protein L18
YPL219W PCL8 0.81 1.0 PHO85 cyclin
YMR106C YKU80 0.81 1.7 "Exhibits DNA binding activity on its own, associates with Hdf1p to form major DNA end-binding complex"
YNL020C ARK1 0.81 1.0 actin regulating kinase
YLR139C SLS1 0.81 1.4 "Protein involved in mitochondrial gene expression, may facilitate translation by delivering mRNAs to membrane-bound translational activation complexes"
YAL024C LTE1 0.81 1.8 Gdp/GTP exchange factor required for growth at low temperatures
YML071C COG8 0.81 0.9 Conserved Oligomeric Golgi complex 8
dependent on RIC1
YLR177W 0.81 0.8
YDR425W 0.81 1.0
YHR081W LRP1 0.81 1.2 Like an rRNA Processing protein
YNL019C 0.81 2.0
YPL188W POS5 0.81 1.1 involved in oxidative stress
YER075C PTP3 0.81 1.0 Protein tyrosine phosphatase
YIL144W TID3 0.81 3.0 S Product of gene unknown
YNL005C MRP7 0.81 0.8 Mitochondrial ribosomal protein MRP7 (YmL2) (E. coli L27)
YCR069W CPR4 0.81 2.2 S cyclophilin homolog
YMR140W SIP5 0.81 1.1 Sip5 facilitates the interaction between the Reg1Glc7 phosphatase and the Snf1 kinase.
YLR464W 0.81 4.5 Z S
YPL241C CIN2 0.81 4.0 S C involvement in microtubule function
YBR033W EDS1 0.81 1.6 Expression dependent on Slt2
YOR178C GAC1 0.81 1.5 "Regulatory subunit for phosphoprotein phosphatase type 1 (PP-1), also known as Glc7p, which regulates glycogen synthase-2"
YLR263W RED1 0.81 1.2 "Required for full chr. pairing & chr. condensation seen by in situ hybridization, axial elements, stable localization of Hop1p & synaptonemal complexes; at HIS2 required for normal levels of double strand breaks"
YMR086W 0.81 1.6
YDR160W SSY1 0.81 1.1 "Ssy1p controls expression of several transporter genes, including BAP2, TAT1, PTR2 and YDR046c"
YOR206W NOC2 0.81 1.8 NucleOlar Complex 2; involved in nuclear export of pre-ribosomes
YDR186C 0.81 1.3
YJR059W PTK2 0.81 1.6 Putative serine/threonine protein kinase that enhances spermine uptake
YDR239C 0.81 1.6
YMR042W ARG80 0.81 2.0 Regulator of arginine-responsive genes with ARG81 and ARG82
YIL010W DOT5 0.81 1.5 Derepression Of Telomeric silencing
homologous to 4 other S.c. thioredoxin peroxidases
YGR249W MGA1 0.81 1.4 Mga1p shows similarity to heat shock transcription factor
YNL033W 0.81 2.0
YLR073C 0.81 1.6
YBR073W RDH54 0.81 3.9 S C genetic interaction with DMC1
YBR225W 0.80 1.5
YHL015W RPS20 0.80 1.1 "Homology to rat S20, human S20, Xenopus S22, and E. coli S10"
YMR232W FUS2 0.80 2.2 "Involved in cell fusion during mating, also required for the alignment of parental nuclei before nuclear fusion"
YMR059W SEN15 0.80 1.4 Trna splicing endonuclease 15kDa subunit
YOR315W 0.80 4.8 S C
YML064C TEM1 0.80 3.4 S Gtp-binding protein of the ras superfamily involved in termination of M-phase
YDR463W STP1 0.80 1.1 Involved in pre-tRNA splicing and in uptake of branched-chain amino acids
YPR079W MRL1 0.80 1.4 Mannose 6-phosphate Receptor Like
YER019C-A SBH2 0.80 1.9 "Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum"
YKR098C UBP11 0.80 2.3 Ubiquitin-specific protease
YPL072W UBP16 0.80 2.0 putative deubiquitinating enzyme
YNL253W 0.80 0.9
YOR078W BUD21 0.80 1.4 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA);
YCR033W SNT1 0.80 1.9 Z
YKL048C ELM1 0.80 3.6 Z S C cell morphology
YEL050C RML2 0.80 1.2 mitochondrial ribosomal protein L2 of the large subunit
YAR050W FLO1 0.80 1.5 FLO5- and FLO8-determined flocculation are considerably less sensitive to mannose than FLO1-determined flocculation.
YPL228W CET1 0.80 1.5 "Interacts with Ceg1p, the mRNA capping enzyme alpha subunit; removes gamma-phosphate from triphosphate-terminated RNA"
YLR238W 0.80 1.4
YOR060C 0.80 1.9
YBR138C HDR1 0.80 4.7 S C High-Dosage Reductional segregation defective. Converts reductional segregation to equational when borne on a 2um plasmid
YKR055W RHO4 0.80 1.6 ras homolog--GTP binding protein
YAL031C FUN21 0.80 1.3 Function unknown now
YLR441C RPS1A 0.80 1.9 Homologous to rat S3A
YKR099W BAS1 0.80 2.1 Transcription factor regulating basal and induced activity of histidine and adenine biosynthesis genes
YLR237W THI7 0.80 2.2 Thiamine Metabolism
YML076C WAR1 0.80 1.1 ORF
YEL002C WBP1 0.80 0.8 wheat germ agglutinin-binding protein
YBR007C 0.80 2.2 S C
YDR115W 0.80 1.3
YDR069C DOA4 0.80 1.0 deubiquitinating enzyme; vacuole biogenesis gene
YER169W RPH1 0.80 1.6 Regulator of PHR1
YMR280C CAT8 0.80 1.4 CAT8 controls the key enzymes of gluconeogenesis in S. cerevisiae.
YPR008W HAA1 0.80 2.6 Homolog of Ace1 Activator
YER032W FIR1 0.80 5.0 Z S C "Factor Interacting with REF2, interacts strongly with REF2 protein in 2-hybrid screen"
YAL046C 0.80 1.0
YOR161C 0.80 1.8
YJL185C 0.80 1.1
YLR290C 0.80 0.8
YMR155W 0.80 1.5
YPL101W ELP4 0.80 1.3 "ELongator Protein 4; 50kD subunit. Homolog of ATPases, yet with substitutions of amino acids critical for ATP hydrolysis."
YML063W RPS1B 0.80 1.7 Homologous to rat ribosomal protein S3A
YML068W ITT1 0.80 1.5 Inhibitor of Translation Termination
YIL171W 0.80 1.7
YOL027C MDM38 0.80 0.9 Mitochondrial Distribution and Morphology
YAL023C PMT2 0.80 2.4 Transfers mannosyl residues from dolichyl phosphate-D-mannose to seryl and threonyl residues in proteins; acts in complex with Pmt1p
YPR032W SRO7 0.80 1.5 Suppressor of rho3
YGR138C TPO2 0.80 4.7 S Polyamine transport protein
YOR127W RGA1 0.80 2.5 S putative GTPase-activating protein for the polarity-establishment protein Cdc42p or Rho1p; activates the pheromone-response pathway
YBL011W SCT1 0.80 1.0 High copy suppresor of choline-transport mutants
YKR046C 0.80 2.6 S
YMR224C MRE11 0.80 0.8 "Disp. for premeiotic DNA synthesis, but required for both double strand break formation & resection, synaptonemal complexes, meiotic recombination & viable spores. Localizes to discrete sites in rad50 mutants"
YHR080C 0.80 1.2
YNL298W CLA4 0.80 1.5 Involved in localizing cell growth with respect to the septin ring
YDL149W APG9 0.80 1.6 Integral membrane protein
YDR006C SOK1 0.80 1.2 gene dosage suppressors of the conditional growth defect of several temperature-sensitive A kinase mutants
YEL042W GDA1 0.80 3.1 S converts nucleoside diphosphates to nucleoside monophosphates to recycle nucleosides and promote transport of additional nucleotide sugars into golgi
YAL010C MDM10 0.79 1.5 Mitochondrial outer membrane protein involved in mitochondrial morphology and inheritance
YKL208W CBT1 0.79 1.0 Subunit of complex involved in processing of the 3' end of cytochrome b pre-mRNA
YKL101W HSL1 0.79 5.0 K Z S C Histone Synthetic Lethal
Negative regulator of Swe1 kinase
YJL095W BCK1 0.79 1.1 bypass requirement for protein kinase C homolog
YKL219W COS9 0.79 1.7 "Protein with similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YML083C 0.79 1.2
YNL080C 0.79 1.3
YDR042C 0.79 1.7
YOL015W 0.79 1.8
YLL003W SFI1 0.79 0.9 Product of gene unknown
YER041W YEN1 0.79 1.1
YER158C 0.79 2.2
YKL122C SRP21 0.79 2.1 part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
YLR296W 0.79 1.7
YEL009C GCN4 0.79 1.5 transcriptional activator of amino acid biosynthetic genes
YJR043C POL32 0.79 3.4 S C Polymerase-associated gene
YHR202W 0.79 1.4
YPL168W 0.79 1.3
YIL152W 0.79 1.3
YHR035W 0.79 1.4
YGL075C MPS2 0.79 2.1 "Monopolar spindle two, encodes a membrane protein localized at the nuclear envelope and the spindle pole body throughout the cell cycle. The protein is approximately 45 kDa, and contains a coiled-coil motif and a hydrophobic domain."
YPR030W CSR2 0.79 1.8 chs5 spa2 rescue; overexpression rescues the lethality of chs5 spa2 at 37 degrees
YLR451W LEU3 0.79 1.3 "Regulates genes involved in branched chain amino acid biosynthesis and in ammonia assimilation. Positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis."
YML016C PPZ1 0.79 1.4 may play a role in regulating osmotic stability
YIL044C AGE2 0.79 0.8 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector
YNL066W SUN4 0.79 2.2 Protein involved in the aging process. Related to glucanases.
YOR037W CYC2 0.79 0.8 Involved in import of cytochrome c into mitochondria
YGR013W SNU71 0.79 0.9 "associated with U1 snRNP (no counterpart in mammalian U1 snRNP; contains few SR-, RE- and RD-dipeptides"
YFR023W PES4 0.79 1.9 Suppressor of DNA polymerase epsilon mutation
YGR130C 0.79 1.0
YGL061C DUO1 0.79 2.7 S Death Upon Overexpression
YEL032W MCM3 0.79 5.4 Z S C Member of complex that acts at ARS's to initiate replication
YPL140C MKK2 0.79 0.9 "Member of MAP kinase pathway involving PKC1, BCK1, and SLT2. Shows functional redundancy with MKK1"
YDR356W SPC110 0.79 3.9 K S C may be involved in connecting nuclear microtubules to the spindle pole body
YAR002W NUP60 0.79 1.1 nuclear pore protein
YFL050C ALR2 0.79 2.3 aluminium resistance
YNR047W 0.79 1.1
YMR163C 0.79 2.7 S
YDR409W SIZ1 0.79 1.1 Sap and mIZ. Contains two known protein motifs: SAP (DNA binding) and MIZ-finger; ubiquitin-like protein ligase 1
YLR214W FRE1 0.79 2.3 S Ferric (and cupric) reductase
YJL201W ECM25 0.79 3.0 Z S ExtraCellular Mutant
YOR338W 0.79 1.8
YBR021W FUR4 0.79 2.1 uracil permease
YIL115C NUP159 0.79 0.8 Located on cytoplasmic side of nuclear pore complex; may be involved in nuclear import or mRNA export; binds to karyopherin beta and a nuclear transport substrate in vitro
YDR369C XRS2 0.79 2.2 "classified as an early recombination function, required for DNA repair but dispensable for mitotic recombination (xrs2 is hyper-Rec during vegatative growth), required for double strand breaks, meiotic recombination and spore viability"
YJL090C DPB11 0.79 1.8 "Part of the DNA polymerase II complex, acts in a checkpoiint pathway during S-phase"
YBL017C PEP1 0.79 1.4 vacuolar protein sorting receptor for carboxypeptidase Y and proteinase A; related to Sortilin
YLR135W SLX4 0.79 1.6 S
YOL034W SMC5 0.79 1.9 S Structural maintenance of chromosomes (SMC) protein
YER026C CHO1 0.79 1.5 phosphatidylserine synthase
YBL113C 0.78 3.9 S
YMR144W 0.78 2.3 S
YOR134W BAG7 0.78 2.3 Structural homolog of SAC7
YHR178W STB5 0.78 2.4 S C binds Sin3p in two-hybrid assay
YOL038W PRE6 0.78 1.1 alpha-type of subunit of 20S proteasome
YOR073W 0.78 4.4 Z S C
YDR312W SSF2 0.78 1.3 high copy suppressor of G beta subunit temperature sensitive mutation
YER096W SHC1 0.78 1.9 Required for proper maturation of the ascospore through its participation in the synthesis of the chitosan layer.
YPR070W MED1 0.78 1.1 Subunit 1 of the Mediator complex essential for transcriptional regulation
YDR207C UME6 0.78 1.2 Regulator of both repression and induction of early meiotic genes. Ume6p requires Ume4 for mitotic repression and interacts with and requires Ime1p and Rim11p for induction of meiosis-specific transcription
YPL093W NOG1 0.78 1.9 Nucleolar G-protein 1; LPG15w (working nomenclature)
YKR024C DBP7 0.78 1.5 Dead-box protein
YJR089W BIR1 0.78 1.0 baculoviral IAP repeat-containing protein
YIL130W GIN1 0.78 1.2 Gcn5 INdependent
YKR064W 0.78 1.1
YGL005C COG7 0.78 1.0 Conserved Oligomeric Golgi complex 7
Complexed with Cog8p
YOR107W RGS2 0.78 1.2 Regulator of G-protein Signalling for gpa2; belongs to the RGS protein family and acts on Gpa2
YGR065C VHT1 0.78 2.0 S vitamin H transporter
YNR066C 0.78 3.9 S
YDR423C CAD1 0.78 1.3 "Transcriptional activator involved in resistance to 1,10-phenanthroline; member of yeast Jun-family of transcription factors related to mammalian c-jun"
YNR068C 0.78 0.8
YJL013C MAD3 0.78 2.0 checkpoint protein required for cell cycle arrest in response to loss of microtubule function
YER111C SWI4 0.78 5.3 K S C Involved in cell cycle dependent gene expression
YOR070C GYP1 0.78 1.3 Gtpase activating protein for Ypt1p
YGR238C KEL2 0.78 2.8 S C "protein containing kelch repeats, similar to YHR158c and YPL263c"
YKR021W 0.78 3.1 S C
YMR261C TPS3 0.78 1.8 115 kD regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex
YGL243W TAD1 0.78 0.9 Deaminates adenosine-37 to inosine in eukaryotic tRNA-Ala.
YOR310C NOP58 0.78 1.2 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); 57 kDa nucleolar protein involved in the pre-rRNA processing steps that lead to formation of 18 S rRNA; interacts with Nop1p
YDL101C DUN1 0.78 3.9 S C "Dun1 kinase has complex checkpoint functions including DNA damage-dependent cell cycle arrest in G(2)M, transcriptional induction of repair genes, and regulation of postreplicative DNA repair pathways."
YMR078C CTF18 0.78 4.3 Z S C Chromosome transmission
YJL002C OST1 0.78 1.8 Oligosaccharyltransferase catalyzes the transfer of oligosaccharide from dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synthesized proteins in ER lumen
YNL069C RPL16B 0.78 1.7 Homology to rat ribosomal protein L13a
YER144C UBP5 0.78 1.2 Putative Ubiquitin-specific protease
YDL220C CDC13 0.78 1.7 "Regulator of telomere replication. Recruits telomerase to the telomere. Required for G2/M transition in mitosis, synaptonemal complexes, recombination, meiosis I, meiosis II, and spores. Dispensable for premeiotic DNA synthesis."
YKR034W DAL80 0.78 1.6 Negative regulator of multiple nitrogen catabolic genes
YNL225C CNM67 0.78 2.6 S C chaotic nuclear migration; predicted mass is 67kDa
YMR180C CTL1 0.78 1.1 CET1-Like Gene #1 (CET1 = capping enzyme triphosphatase 1)
YMR036C MIH1 0.78 1.1 Mitotic Inducer Homolog
S. pombe cdc25+ homolog
YGL251C HFM1 0.78 1.3 DNA helicase that functions in meiotic crossing over
YNL076W MKS1 0.78 0.9 Pleiotropic regulatory factor involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation
YJL179W PFD1 0.78 1.1 "Prefoldin subunit 1; putative homolog of subunit 1 of bovine prefoldin, a chaperone comprised of six subunits"
YDR251W PAM1 0.78 2.4 multicopy suppressor of protein phosphatase 2A
YHR065C RRP3 0.77 1.0 Required for maturation of the 35S primary transcript of pre-rRNA and is required for cleavages leading to mature 18S RNA
YJL025W RRN7 0.77 0.9 involved in the transcription of 35S rRNA genes by RNA polymerase I
YJL214W HXT8 0.77 1.6 High-affinity hexose transporter
YDR522C SPS2 0.77 2.2 Middle/late gene of meiosis
YPL030W 0.77 1.5
YMR067C 0.77 1.4
YDR406W PDR15 0.77 1.3 similar to Pdr5p and Pdr10p
YFL032W 0.77 1.1
YBR172C SMY2 0.77 2.0 partial suppressor of myo2-66
YGL167C PMR1 0.77 0.8 "Ca++-Pump, ATPase"
YCR039C MATALPHA2 0.77 2.0 "Homeobox-domain containing protein which, in haploid cells, acts with MCM1 to repress a-specific genes. In diploid cells alpha2 acts together with a1 to repress transcription of haploid-specific genes."
YCL067C HMLALPHA2 0.77 1.6 "Homeobox-domain containing protein which, in haploid cells, acts with MCM1 to repress a-specific genes. In diploid cells alpha2 acts together with a1 to repress transcription of haploid-specific genes."
YAL001C TFC3 0.77 1.4 C transcription factor tau (TFIIIC) subunit 138
YHR095W 0.77 1.8
YKL162C 0.77 1.9
YDR261C EXG2 0.77 2.2 S "Exo-1,3-b-glucanase"
YLR110C CCW12 0.77 2.2
YKL043W PHD1 0.77 3.7 S protein similar to StuA of Aspergillus nidulans
YDL035C GPR1 0.77 1.4 G-protein-coupled receptor at plasma membrane; interactions in two-hybrid system with Gpa2p
YKL093W MBR1 0.77 1.6 Involved in mitochondrial biogenesis
YKR042W UTH1 0.77 4.5 S "Youth, involved in determining yeast longevity"
YIL087C 0.77 1.4
YGL161C 0.77 1.2
YJL192C 0.77 1.1
YLR260W LCB5 0.77 1.0 involved in sphingolipid biosynthesis
YPL146C 0.77 1.3
YIL149C MLP2 0.77 1.3 involved in translocation of macromolecules between the nucleoplasm and the NPC
YDL083C RPS16B 0.77 2.5 Homology to rat S16
YNL144C 0.77 1.4
YBR295W PCA1 0.77 1.2 thought to play a role in resistance to copper ion toxicity
YNR038W DBP6 0.77 1.2 Dead Box Protein 6
YDR067C 0.77 1.2
YLR005W SSL1 0.77 0.8 Component of RNA polymerase transcription factor TFIIH
YMR133W REC114 0.77 1.1 "meiosis-specific recombination gene; dispensable for mitotic recombination and axial elements in meiosis but required for synaptonemal complexes, meiotic recombination, and spore viability; classified as an early recombination gene"
YCR091W KIN82 0.77 2.4 Putative serine/threonine protein kinase most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily
YPL038W MET31 0.77 1.1 Involved in methionine metabolism
YPR005C HAL1 0.77 2.2 "Protein induced by NaCl, KCl, or sorbitol; involved in halotolerance (tolerance to salt)"
YDR323C PEP7 0.77 1.0 vacuolar segregation protein required for vacuole inheritance and vacuole protein sorting
YAR071W PHO11 0.77 5.7 S "Acid phosphatase, secreted"
YDL204W RTN2 0.77 1.2 reticulon gene member of the RTNLA (reticulon-like A) subfamily
YOR371C GPB1 0.77 1.1 "Gpa2 interacting partner; Homolog of GPB2
Functions, with Gpb2, in the cAMP-PKA pathway via interactions with Gpa2 and another unknown target."
YGL023C PIB2 0.77 0.9 Phosphatidylinositol 3-phosphate binding
YOL078W AVO1 0.77 0.8 Adheres VOraciously (to TOR2)
YDR191W HST4 0.77 5.6 Z S Homolog of SIR2
YLL027W ISA1 0.77 1.7 Iron Sulfur Assembly -- IscA/NifA homolog
YJR046W TAH11 0.77 1.0 Essential protein.
YJL073W JEM1 0.76 2.8 S C DnaJ-like protein of the endoplasmic reticulum membrane
YOR378W 0.76 2.3
YMR141C 0.76 1.3
YOR004W 0.76 1.1
YBR114W RAD16 0.76 2.4 Nucleotide excision repair protein with DNA helicase domain of Snf2p family
YDR501W PLM2 0.76 3.9 S Plasmid Maintenance
YMR184W 0.76 1.3
YPR025C CCL1 0.76 1.5 essential for cell proliferation
YDL224C WHI4 0.76 1.1 whi (Wee) mutants give small cell size
YOR052C 0.76 2.8 S
YFR051C RET2 0.76 1.4 coatomer (COPI) complex delta subunit
YFR016C 0.76 1.1
YHR006W STP2 0.76 2.6 S Involved in pre-tRNA splicing and in uptake of branched-chain amino acids
YOL011W PLB3 0.76 3.1 S Phospholipase B
YDR089W 0.76 3.8 Z S
YKR095W MLP1 0.76 1.0 involved in translocation of macromolecules between the nucleoplasm and the NPC
YLR175W CBF5 0.76 0.9 major low affinity 55 kDa Centromere/microtubule binding protein
YOR216C RUD3 0.76 0.8 Relieves uso1-1 transport defect; golgin-160 related protein
YIL150C DNA43 0.76 1.6 Protein required for S-phase (DNA synthesis) initiation or completion
YLR371W ROM2 0.76 0.8 Gdp-GTP Exchange Protein (GEP) for the Rho1p Small GTP-binding Protein; high copy suppressor of cik1 and kar3 deletion mutants.
YCL061C MRC1 0.76 4.2 S C Mediator of the Replication Checkpoint; required for full activation of Rad53p in response to replication stress.
YHR175W CTR2 0.76 1.6 Putative low-affinity copper transport protein
YMR008C PLB1 0.76 2.3 Responsible for the production of the deacylation products of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol
YKR093W PTR2 0.76 2.6 Functions in transport of small peptides into the cell
YMR290C HAS1 0.76 1.6 Helicase Associated with SET1
YBR045C GIP1 0.76 1.1 Developmentally-regulated protein phosphatase 1 (Glc7) interacting protein which is required for spore formation.
YPR157W 0.76 5.3 Z S C
YOR195W SLK19 0.76 3.6 Z S synthetic lethal KAR3
YNL218W MGS1 0.76 1.3 Maintenance of Genome Stability 1
YDR124W 0.76 2.1
YLR119W SRN2 0.76 1.5 Suppressor of rna1-1 mutation
YOR047C STD1 0.76 1.2 interacts with the SNF1 protein kinase and TBP in two-hybrid and in in vitro binding studies
YER132C PMD1 0.76 0.9 Paralog of MDS3
YHR126C 0.76 2.9 S
YLL002W RTT109 0.76 4.5 Z S C "Regulator of Ty1 Transposition; Regulation of mitochondrial network; Killed in Mutagen, sensitive to diepoxybutane and/or mitomycin C"
YHL027W RIM101 0.76 0.9 Regulator of IME2 (RIM)
Rim101p is similar to the Aspergillus Phenotype-response regulator PacC and the Yarrowia proteinase YlRim1010p; transcriptional activator required for entry into meiosis
YPR013C 0.76 2.1 S
YLR091W 0.76 1.0
YJL222W VTH2 0.76 0.8 vps ten homolog
YHR215W PHO12 0.76 3.5 S "acid phosphotase, nearly identical to Pho11p"
YOR272W YTM1 0.76 1.3 microtubule-associated protein
YPL032C SVL3 0.76 2.9 Z S Styryl dye vacuolar localization
YLR228C ECM22 0.76 1.2 C involved in cell wall biogenesis (putative)
YNL240C NAR1 0.76 1.1 Nuclear architecture related protein with homology to human Narf (Nuclear prelamin A Recognition Factor)
YKL025C PAN3 0.76 1.5 Dun1 and Pan2-Pan3 cooperate to regulate the stoichiometry and activity of postreplication repair complexes.
YLR343W 0.76 2.7 S
YNL206C RTT106 0.76 1.9 "Regulator of Ty1 Transposition - same phenotype as RTT101 - RTT105, disruption causes increase in Ty1 transposition. Isolated from the same screen as the other named RTT genes."
YDR326C 0.76 1.6
YDR331W GPI8 0.76 1.4 Protein involved in the attachment of glycosylphosphatidylinositol (GPI) anchors to proteins
YBR059C AKL1 0.76 1.1 Ark-family kinase-like protein. This protein is the third member (After Ark1p and Prk1p) of the Ark-family kinases in S. cerevisiae.
YBL019W APN2 0.76 1.5 "AP endonuclease 2, homolog of human HAP1 and E. coli exoIII"
YMR075W RCO1 0.76 1.9 Hypothetical ORF
YPR019W CDC54 0.76 4.8 S C essential for initiation of DNA replication; homolog of S. pombe CDC21
YGL148W ARO2 0.76 1.2 Chorismate synthase
YOR346W REV1 0.76 1.4 Protein required for mutagenesis by physical and chemical agents
YGL093W SPC105 0.76 3.1 Z S Spindle Pole Component of molecular weight 105kDa
YNR019W ARE2 0.76 1.4 Acyl-CoA cholesterol acyltransferase (sterol-ester synthetase)
YAL017W PSK1 0.76 1.3 contains serine/threonine protein kinase domain and shows homology with the SNF1 serine/threonine protein kinase
YDR458C 0.76 1.1
YBR150C TBS1 0.76 1.6 Probable Zn-finger protein
YML112W CTK3 0.76 1.4 CTD kinase-I gamma subunit
YBR098W MMS4 0.76 2.2 endonuclease
YHR182W 0.76 1.0
YDR452W PPN1 0.76 1.0 Phosphate metabolism; transcription is regulated by PHO system
YHR158C KEL1 0.75 1.6 "protein containing kelch repeats, similar to YGR238c"
YPL094C SEC62 0.75 1.5 membrane component of ER protein translocation apparatus
YPL221W BOP1 0.75 3.4 S bypass of PAM1
YMR004W MVP1 0.75 1.3 Protein required for sorting proteins to the vacuole
YNR011C PRP2 0.75 0.8 Dead-box protein required for the first catalytic event of pre-mRNA splicing.
YGR282C BGL2 0.75 2.3 "Cell wall endo-beta-1,3-glucanase"
YLR081W GAL2 0.75 1.3 "Galactose transport, also able to transport hexoses"
YJL069C UTP18 0.75 1.3 U3 protein
YBR263W SHM1 0.75 1.4 "Serine hydroxymethyltransferase, mitochondrial"
YLR417W VPS36 0.75 1.4 Defective in vacuolar protein sorting
YPL026C SKS1 0.75 1.7 multicopy suppressor of snf3 and grr1 mutants
YCR084C TUP1 0.75 2.2 C general repressor of transcription (with Cyc8p); mediates glucose repression
YDL159W STE7 0.75 0.9 "Serine/threonine/tyrosine protein kinase of the pheromone pathway, homologous to MAP kinase kinase family"
YOR016C ERP4 0.75 1.4 Emp24p/Erv25p related protein 4
YOR219C STE13 0.75 1.2 dipeptidyl aminopeptidase
YDR446W ECM11 0.75 2.5 ExtraCellular Mutant
YMR265C 0.75 1.7
YLR018C POM34 0.75 1.3 nuclear pore integral membrane protein
YAR035W YAT1 0.75 1.2 "Outer carnitine acetyltransferase, mitochondrial"
YOR175C 0.75 1.9
YPL016W SWI1 0.75 2.1 C "Global transcription activator that acts in complex with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators; involved in the regulation of expression of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2"
YDR033W MRH1 0.75 8.1 K S C "Membrane protein related to Hsp30p; Localized by immunofluorescence to membranes, mainly the plasma membr. punctuate immunofluorescence pattern observed in buds. The nuclear envelope, but not vacuole or mitochondrial membranes also stained"
YLL035W GRC3 0.75 0.9 Product of gene unknown
YJL157C FAR1 0.75 6.3 K S C Factor arrest protein
YDR523C SPS1 0.75 3.7 "dispensable for mitosis, involved in middle/late stage of meiosis, required for spore wall formation"
YIL173W VTH1 0.75 1.2 vps ten homolog
YFL033C RIM15 0.75 1.8 RIM15 is glucose-repressed; RIM15 is required for IME2 expression
YCR028C FEN2 0.75 0.9 Fenpropimorph resistance gene. Protein shows similarity to Dal5p and members of the allantoate permease family of the major facilitator superfamily (MFS).
YGR042W 0.75 2.8 S
YFL024C EPL1 0.75 1.6 "Enhancer of Polycomb-Like (from D. melanogaster). Subunit of the Nucleosomal Acetyltransferase of H4 complex (NuH4). May be required for silencing in S. cerevisiae, based on analogous functions within other eukaryotes."
YBR270C 0.75 1.0
YNR065C YSN1 0.75 1.0 Yeast SortiliN 1
YPL248C GAL4 0.75 1.2 Positive regulator of GAL genes
YER089C PTC2 0.75 1.2 Protein phosphatase type 2C
YNL054W VAC7 0.75 1.5 Integral 128-kDa vacuolar membrane protein; may function to regulate Fab1 kinase activity.
YIL004C BET1 0.75 1.2 Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins
YPR133C IWS1 0.75 1.0 Interacts with Spt6
YJL112W MDV1 0.75 1.6 WD repeat protein that regulates steps in the Dnm1p-dependent process of mitochondrial fission.
YMR212C EFR3 0.75 1.1 PHO _E_ighty _F_ive _R_equiring
YKR056W TRM2 0.75 1.5 tRNA methyltransferase
YJL174W KRE9 0.75 1.2 cell wall beta-glucan assembly
YBR298C MAL31 0.75 1.9 "Part of the complex locus MAL3; functional in S288C; highly homologous to MAL61 from S. cerevisiae, MAL61 from S. carlsbergenesis strains JM1901 and CB11, and MAL1T from strain 4059"
YLR131C ACE2 0.75 5.6 K Z S C involved in transcriptional regulation of CUP1
YNR006W VPS27 0.75 1.3 hydrophilic protein; has cysteine rich putative zinc finger esential for function
YOR148C SPP2 0.75 1.0 Required for final stages of splicesome maturation; promotes step 1 of splicing
YPR081C GRS2 0.74 1.4 "Possible pseudogene; has similarity to Grs1p glycyl-tRNA synthetase, but expression is very low and GRS2 cannot substitute for GRS1"
YPL169C MEX67 0.74 1.2 "Involved in nuclear mRNA export, binds both poly(A)"
YIL127C 0.74 1.5
YPR106W ISR1 0.74 5.5 S Inhibition of staurosporine resistance
YOR205C 0.74 1.3
YDR419W RAD30 0.74 0.9 Radiation sensitive. Replication fork is protected from inaccurate synthesis by Pol eta in the absence of DNA damage.
YEL057C 0.74 1.0
YER167W BCK2 0.74 1.2 Serine/threonine protein kinase of the protein kinase C pathway
YDR034C LYS14 0.74 1.7 Transcriptional activator of lysine pathway genes with 2-aminoadipate semialdehyde as co-inducer; saccharopine reductase synthesis
YPR185W APG13 0.74 1.7 autophagy
YBR093C PHO5 0.74 2.0 S "Acid phosphatase, repressible"
YHL050C 0.74 4.0 Z S
YDR317W 0.74 1.0
YKL105C 0.74 1.3
YNL339C YRF1-6 0.74 4.5 Z S Y'-helicase protein 1
YIR039C YPS6 0.74 1.1 Gpi-anchored aspartic protease (Yapsin 6)
YPL020C ULP1 0.74 1.3 Ubl (ubiquitin-like protein)-specific protease 1; initially processes Smt3; also acts as a deconjugating enzyme for Smt3
YPR181C SEC23 0.74 0.8 cytoplasmic GTPase-activating protein
YGL083W SCY1 0.74 1.8 Suppressor of GTPase mutant
YLR013W GAT3 0.74 2.7 S The amino acid sequence of this ORF is very homologous to that of GAT4/YIR013C.
YPL283C YRF1-7 0.74 3.6 S Y'-helicase protein 1
YGR296W YRF1-3 0.74 4.4 Z S Y'-helicase protein 1
YHR031C RRM3 0.74 2.1 C involved in rDNA replication and Ty1 transposition
YKL222C 0.74 1.1
YHR195W NVJ1 0.74 1.3 Vac8p binding protein; nucleus-vacuole junction
YER005W YND1 0.74 0.8 Yeast Nucleoside Diphosphatase
YDL027C 0.74 2.7
YJL105W SET4 0.74 2.6
YOR033C EXO1 0.74 3.2 Z S Protein that complements a drug-hypersensitive mutation. EXO1 plays a structural role in MMR and stabilizes multiprotein complexes containing a number of MMR proteins.
YDR095C 0.74 1.6
YPR090W 0.74 1.2
YGR089W 0.74 1.9
YLR086W SMC4 0.74 0.9 Stable Maintenance of Chromosomes
YPL133C RDS2 0.74 2.1 S C Regulator of drug sensitivity
YOR217W RFC1 0.74 1.3 RFC is a DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA
YBR229C ROT2 0.74 1.3 "Reversal of tor2 lethality. Involved in Beta-1,6-glucan synthesis."
YKL055C OAR1 0.74 1.3 3-oxoacyl-[acyl-carrier-protein] reductase
YCL039W 0.74 1.0
YIL091C 0.74 0.9
YKL189W HYM1 0.74 1.5 "The homolog in Aspergillus nidulans, hymA, is involved in development, see Karos, M. and Fischer, R. (1996). hymA (hypha-like metulae), a new developmental mutant of Aspergillus nidulans. Microbiol. 142:3211-3218."
YGL201C MCM6 0.74 3.1 S C Member of the MCM/P1 family of proteins involved in DNA replication
YNR053C NOG2 0.74 1.4 Nuclear/Nucleolar GTP-binding protein 2
YEL060C PRB1 0.74 2.8 S "dispensable for haploidization and sporulation, but needed for full protein degradation during sporulation, and proper spore morphology"
YMR007W 0.74 2.4 C
YHR039C MSC7 0.74 1.8 C Meiotic Sister-Chromatid recombination
YDR359C VID21 0.74 1.2 Vacuolar import degradation
YOR088W 0.74 1.5
YDR109C 0.74 1.1
YAR033W 0.74 1.3
YKL168C KKQ8 0.73 1.6 Serine/threonine protein kinase of unknown function
YML035C AMD1 0.73 1.7 putative alpha-mannosidase
YOR328W PDR10 0.73 1.2 Putative ABC transporter highly similar to Pdr5p
YFL051C 0.73 4.0
YKR094C RPL40B 0.73 1.2 Homology to rat L40
YIL148W RPL40A 0.73 1.3 Homology to rat L40
YHR097C 0.73 2.9
YJL096W MRPL49 0.73 1.6 mitochondrial ribosomal protein of the large subunit
YMR231W PEP5 0.73 2.0 peripheral vaculor membrane protein; putative Zn-finger protein
YLL019C KNS1 0.73 1.2 protein kinase homolog
YOL019W 0.73 5.0 S C
YDL095W PMT1 0.73 2.6 Z S C Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway; acts in complex with Pmt2p
YJL168C SET2 0.73 1.9 Contains a 'SET' or 'TROMO' domain at the N-terminus of the protein
Methyltransferase activity is important for transcriptional repression activity
YKR097W PCK1 0.73 1.4 phosphoenolpyruvate carboxylkinase
YJL219W HXT9 0.73 3.1 High-affinity hexose transporter
YGL178W MPT5 0.73 1.7 Product of gene unknown
YPR022C 0.73 1.1
YBR028C 0.73 1.6
YBR292C 0.73 1.2
YLR257W 0.73 1.3
YDL058W USO1 0.73 0.9 "involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi"
YOR208W PTP2 0.73 1.6 protein tyrosine phosphatase
YDR266C 0.73 1.7
YBR182C SMP1 0.73 1.7 "Second MEF2-like Protein 1
Transcription factor of the MADS (Mcm1p, Agamous, Deficiens, SRF) box family; closely related to RLM1"
YDR011W SNQ2 0.73 2.4 S ABC transporter
YMR242C RPL20A 0.73 1.2 Homology to rat L18a
YNR023W SNF12 0.73 1.5 "73 kDa subunit of the SWI/SNF transcription activation complex, homolog of Rsc6p subunit of the RSC chromatin remodeling complex"
YMR011W HXT2 0.73 5.7 S hexose transporter
YLR187W 0.73 1.8
YLR413W 0.73 4.2 S
YLR410W VIP1 0.73 1.1 Homologous to S. pombe asp1+
YOR028C CIN5 0.73 1.7 Protein involved in silencing
YBR233W PBP2 0.73 2.0 Overexpression confers resistance to the antimalarial drug mefloquine
YJL005W CYR1 0.73 1.3 "Required for START A of cell cycle, and glucose and nitrogen repression of sporulation"
YLR002C NOC3 0.73 1.2 NucleOlar Complex 2; involved in the nuclear export of pre-ribosomes
YGR170W PSD2 0.73 1.0 converts phosphatidylserine to phosphatidylethanolamine
YNL289W PCL1 0.73 4.4 K S C G(sub)1 cyclin that associates with PHO85
YOR171C LCB4 0.73 1.4 involved in sphingolipid biosynthesis
YJL194W CDC6 0.73 4.1 K S C Protein involved in initiation of DNA replication
YJL191W RPS14B 0.73 1.5 "Homology to human S14 and rat S14, E. coli S11"
YDR273W DON1 0.73 1.3 prospore membrane localizing protein
YMR272C SCS7 0.73 1.3 "Required for the hydroxylation of the very long chain fatty acid (VLCFA), located in the endoplasmic reticulum"
YAL055W PEX22 0.73 1.0 Product of gene unknown
YGR223C 0.73 1.3
YPR121W THI22 0.73 1.5 THI for thiamine metabolism. Transcribed in the presence of low level of thiamine (10-8M) and turned off in the presence of high level (10-6M) of thiamine. Under the positive control of THI2 and THI3.
YNL106C INP52 0.73 1.4 Synaptojanin-like protein
YGR260W TNA1 0.73 2.0 S Transporter of Nicotinic Acid
YGR159C NSR1 0.73 1.4 nuclear localization sequence binding protein
YDR389W SAC7 0.73 1.7 C Suppressor of actin mutation
YDR206W EBS1 0.72 0.9 EST1-like bcy1 Suppressor
YNL326C 0.72 1.8 S
YPL194W DDC1 0.72 1.7 DNA damage checkpoint gene
YCR095C 0.72 0.8
YER137C 0.72 1.0
YDR484W SAC2 0.72 0.8 May interact with actin as a component or controller of the assembly or stability of the actin cytoskeleton
YBR161W 0.72 3.2 Z S
YDR137W RGP1 0.72 1.0 "Ric1p-Rgp1p is an exchange factor, and peripheral membrane protein complex restricted to the Golgi."
YLR069C MEF1 0.72 1.4 mitochondrial elongation factor G-like protein
YDL214C PRR2 0.72 2.1
YFL054C 0.72 2.0
YOR214C 0.72 1.3
YIL047C SYG1 0.72 2.5 Protein for which truncation and overexpression can suppress lethality of G-alpha protein deficiency
YLR080W EMP46 0.72 1.2 Evidence suggests that Emp46p and Emp47p are required for the export of specific glycoprotein cargo from the endoplasmic reticulum.
YGR126W 0.72 0.8
YER152C 0.72 2.9 S
YOL053W 0.72 1.1
YML061C PIF1 0.72 3.1 S C involved in repair and recombination of mitochondrial DNA; also plays a role in (nuclear) chromosomal telomere formation and elongation
YJL127C SPT10 0.72 0.9 chromatin maintenance and transcriptional regulation
YGR056W RSC1 0.72 1.0 "RSC1 is a member of RSC complex, which remodels the structure of chromatin"
YDR060W MAK21 0.72 2.2 essential for 60s ribosome biogenesis; involved in nuclear export of pre-ribosomes
YFR027W ECO1 0.72 3.8 Z S C Establishment of COhesion
YDR120C TRM1 0.72 1.4 "N2,N2-dimethylguanosine-specific tRNA methyltransferase"
YLR443W ECM7 0.72 1.0 Involved in cell wall maintenance
YHR092C HXT4 0.72 2.2 S hexose transporter
YMR129W POM152 0.72 1.6 May be involved in duplication of nuclear pores and nuclear pore complexes during S-phase
YMR118C 0.72 1.4
YDR348C 0.72 1.9
YNL245C CWC25 0.72 1.0 Complexed with Cef1p
YCR031C RPS14A 0.72 2.8 "Homology to mammalian S14, E. coli S11"
YDL025C 0.72 0.9
YPL260W 0.72 0.8
YGL249W ZIP2 0.72 1.2 Required for 'ZIPpering' up meiotic chromosomes during chromosome synapsis
YDR311W TFB1 0.72 1.1 "Component of transcription initiation factor IIb, 75 kDa subunit"
YDL160C DHH1 0.72 1.9 Putative RNA helicase of DEAD box family
YDR520C 0.72 1.0
YKL086W 0.72 1.5
YEL076C 0.72 4.5 S
YOR255W 0.72 2.4
YBR181C RPS6B 0.72 1.2 "Homology to rat, human, and mouse S6"
YPL090C RPS6A 0.72 1.3 "Homology to rat, mouse, and human S6"
YOR308C SNU66 0.72 4.9 S 66kD U4/U6.U5 snRNP associated protein
YDR009W GAL3 0.72 1.4 Involved in galactose induction of GAL genes
YKR029C SET3 0.72 1.7
YDR264C AKR1 0.72 1.2 Negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control
YIR003W 0.72 1.5
YLR138W NHA1 0.72 1.2 Putative Na+/H+ antiporter
YHL026C 0.72 5.0 S C
YDR213W UPC2 0.72 1.5 involved in sterol uptake
YFR033C QCR6 0.72 1.3 ubiquinol-cytochrome c oxidoreductase subunit 6 (17 kDa)
YNL159C ASI2 0.72 1.2 "Amino acid Sensor-Independent (ASI) genes encode membrane proteins Asi1p, Asi2p and Asi3p."
YOL111C 0.72 1.4
YCR023C 0.72 1.7
YJL080C SCP160 0.72 1.3 "May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes, involved in control of mitotic chromsome transmission"
YJL033W HCA4 0.72 1.7 putative RNA helicase
YOR260W GCD1 0.72 1.0 general control of amino acid biosynthesis and cell cycle initiation
YHR213W 0.72 1.0
YHR015W MIP6 0.72 1.7 "RNA-binding protein, interacts with MEX67"
YOR344C TYE7 0.72 1.4 may be involved in glycolytic gene expression
YEL017W 0.71 4.6 Z S C
YFR029W PTR3 0.71 0.9 "Regulator of expression of the PTR2, GAP1, and BAP2 genes; involved in the the control of peptide transport"
YDR336W 0.71 0.8
YIL072W HOP1 0.71 1.1 S Meiosis-specific protein involved in homologous chromosome synapsis and chiasmata formation
YOR373W NUD1 0.71 3.3 Z C Spindle pole body protein
YDR472W TRS31 0.71 1.3 targeting complex (TRAPP) component involved in ER to Golgi membrane traffic
YOR172W 0.71 1.0
YOR106W VAM3 0.71 0.9 Syntaxin-related protein; required for vacuolar assembly; PEP12 homolog
YOL103W ITR2 0.71 1.3 member of sugar transporter superfamily
YKL160W 0.71 1.1
YER155C BEM2 0.71 1.4 Protein with role in bud emergence
YJL144W 0.71 1.7
YOR153W PDR5 0.71 5.6 S multidrug resistance transporter
YAL042W ERV46 0.71 1.0 ER vesicle protein of 46 kDa
YBR184W 0.71 2.0 C
YJR080C 0.71 1.0
YIL135C 0.71 1.7 S
YIR031C DAL7 0.71 1.9 allantoin pathway
YIL158W 0.71 5.7 S C
YHL029C 0.71 1.1
YHR085W IPI1 0.71 1.0 Involved in Processing ITS2
YLR336C SGD1 0.71 1.3 Suppressor of Glycerol Defect
YPR138C MEP3 0.71 2.7 S ammonia permease of high capacity and low affinity; shows sequence similarity to Mep1p and Mep2p
YDR076W RAD55 0.71 1.2 "Required for X-ray damage repair, full sporulation and viable spores"
YER022W SRB4 0.71 0.9 subunit of RNA polymerase II holoenzyme/mediator complex
YOL029C 0.71 1.5
YDL231C BRE4 0.71 1.4 contains several putative trans-membrane domains
YMR171C 0.71 0.9
YMR157C 0.71 1.6
YLR344W RPL26A 0.71 2.0 Homology to rat L26
YMR190C SGS1 0.71 3.1 C "Involved in maintaining genome stability. Homologous to E. coli RecQ and human BLM and WRN proteins that are defective in the cancer-prone disorder Bloom's syndrome and the premature aging disorder Werner's syndrome, respectively"
YNR070W PDR18 0.71 1.6 pleiotropic drug resistance
YCL055W KAR4 0.71 3.9 K S May assist Ste12p in pheromone-dependent expression of KAR3 and CIK1
YBL059W 0.71 1.3
YNL236W SIN4 0.71 1.0 "involved in positive and negative regualtion of transcription, possibly via changes in chromatin structure; regulation of YGP1 expression"
YOL156W HXT11 0.71 2.1 High-affinity hexose transporter
YLR023C 0.71 1.1
YHR079C IRE1 0.71 1.1 Involved in myo-inositol biosynthesis; implicated as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus
YJL077C ICS3 0.71 1.0 Increased Copper Sensitivity
YJL187C SWE1 0.71 5.3 K Z S C Protein kinase that inhibits G2/M transition.
S. pombe wee1+ homolog
YGR080W TWF1 0.71 1.0 "Twinfilin A is a member of a conserved family of actin monomer sequestering proteins. TWF1 is comprised almost entirely of two tandem repeats, each having sequence homology with cofilin (COF1)."
YMR109W MYO5 0.71 1.2 contains proline-rich tail homology 2 (TH2) and SH3 domains
YNL188W KAR1 0.71 1.1 "involved in spindle pole body duplication and karyogamy, interacts with Cdc31p, localizes to the spindle pole body"
YJL042W MHP1 0.71 1.1 Similar to a 250 kD Drosophila microtubule-associated protein (MAP) (which can rescue MHP1 null mutant) and to mammalian MAP4 proteins
YJR110W 0.71 2.2 S C
YPL259C APM1 0.71 0.9 medium subunit of the clathrin-associated protein complex
YNL295W 0.71 1.1
YDR358W GGA1 0.70 1.9 "Golgi-localized, gamma-adaptin homology, Arf-binding. Interacts with Arf1p and Arf2p in a GTP-dependent manner. Effector of Arf that facilitates traffic through the late Golgi."
YOR230W WTM1 0.70 2.8 S WD repeat containing transcriptional modulator 1
YPL164C MLH3 0.70 1.1 Mutl Homolog
YDL155W CLB3 0.70 1.9 K C Involved in mitotic induction and perhaps in DNA replication and spindle assembly
YCL034W LSB5 0.70 1.7 LAs17 Binding protein
YGL156W AMS1 0.70 1.7 vacuolar alpha mannosidase
YIR033W MGA2 0.70 2.0 Product of gene unknown
YNL257C SIP3 0.70 0.8 Interacts with SNF1 protein kinase
YOR030W DFG16 0.70 1.3 "Involved in cell wall maintenance, filamentous growth"
YHR118C ORC6 0.70 1.5 origin recognition complex (ORC) component that binds to origins of replication and thereby directs DNA replication and is also involved in transcriptional silencing
YHR219W 0.70 3.5 S
YDR117C 0.70 1.3
YHR069C RRP4 0.70 0.8 Ribosomal RNA Processing
YML114C TAF8 0.70 0.9 TBP Associated Factor 65 KDa
YOL003C 0.70 1.5
YPL100W MAI1 0.70 0.8 Maturation of pro-AmInopeptidase I (proAPI) defective; protein similar to Aut10p and YGR223Cp with three putative WD repeats
YBR217W APG12 0.70 1.2 autophagy
YOR090C PTC5 0.70 1.0 Phosphatase type Two C
YNL238W KEX2 0.70 1.8 Z "prohormone processing; golgi localization marker, dispensable for meiotic recombination but partially required for meiosis I and/or meiosis II"
YMR054W STV1 0.70 1.8 Stv1p and Vph1p may be equivalent subunits for vacuolar-type H(+)-ATPases located on different organelles
YOL163W 0.70 1.3
YJL118W 0.70 4.9 Z S C
YOR081C 0.70 1.7
YAL037W 0.70 1.4
YIL019W 0.70 1.8
YLR352W 0.70 1.7
YNL177C 0.70 0.8
YOL154W ZPS1 0.70 2.3 "Zinc and pH regulated Surface protein. Similar to Candida albicans protein Pra1, a pH-regulated cell surface glycoprotein with weak similarity to zinc metalloproteinases."
YCL052C PBN1 0.70 1.3 Protease B Non-derepressible
YMR165C SMP2 0.70 1.8 involved in plasmid maintenance
YLR452C SST2 0.70 4.0 K S Protein involved in desensitization to alpha-factor pheromone
YDR108W GSG1 0.70 1.3 Probably has role late in meiosis following DNA replication
YCR014C POL4 0.70 0.8 Probable homolog of mammalian DNA polymerase beta; may function in double-stranded DNA break repair
YIL162W SUC2 0.70 2.6 S C invertase (sucrose hydrolyzing enzyme)
YBR086C IST2 0.70 3.7 S Similar to calcium and sodium channel proteins
YNL071W LAT1 0.70 0.8 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex
YBL092W RPL32 0.70 1.0 Homology to rat L32 and mammalian L32
YDL117W CYK3 0.70 4.7 S C involved in CYtoKinesis
YDL092W SRP14 0.70 0.8 Signal recognition particle subunit
YER038C KRE29 0.70 1.1 Killer toxin REsistant
YNL254C 0.70 1.4
YJL083W 0.70 1.2
YER087C-A 0.70 1.6
YPR145W ASN1 0.70 0.8 Asn1p and Asn2p are isozymes
YCL049C 0.70 1.2
YNL116W 0.70 1.8 Z
YPL075W GCR1 0.70 2.9 S trans-acting positive regulator of the enolase and glyceraldehyde-3-phosphate dehydrogenase gene families
YLR026C SED5 0.70 0.9 Sed5p is a t-SNARE (soluble NSF attachment protein receptor) required in ER to Golgi transport.
YDR240C SNU56 0.70 0.8 Snurp = Small nuclear ribonucleoprotein particle of MW 56 kDa. Associated with the U1 snRNP; no counterpart in mammalian U1 snRNP. Serine-rich.
YFR057W 0.70 2.1
YGR112W SHY1 0.70 1.1 involved in respiration
YMR137C PSO2 0.70 1.4 DNA cross-link repair protein
YGL050W 0.70 1.1
YJL107C 0.70 1.7
YOR231W MKK1 0.70 1.3 Mitogen-activated kinase-kinase involved in protein kinase C pathway
YJR049C UTR1 0.70 1.1 associated with ferric reductase
YJL010C 0.70 1.2
YGR038W ORM1 0.70 1.4 Product of gene unknown
YKL116C PRR1 0.70 4.8 S C
YPL230W 0.70 1.3
YLR310C CDC25 0.70 1.0 cell division cycle blocked at 36 degree C
YGR241C YAP1802 0.70 1.0 "Yeast Assembly Polypeptide, member of AP180 protein family, binds Pan1p and clathrin"
YMR037C MSN2 0.70 1.5 Transcription factor. Multicopy suppressor of snf1 mutation. Key regulator of stress-responsive gene expression.
YLR407W 0.69 1.2
YBR291C CTP1 0.69 1.3 citrate transport protein
YDR049W 0.69 1.8
YPR169W JIP5 0.69 0.8 Jumonji Interacting Protein
YDR506C 0.69 0.8
YPR091C 0.69 1.5
YBR290W BSD2 0.69 1.3 metal homeostasis protein; putative membrane protein
YLL008W DRS1 0.69 1.3 nucleolar DEAD-box protein required for synthesis of 60S ribosomal subunits
YDL225W SHS1 0.69 1.0 Interacts with Spa2p and plays a role in cytokinesis
YOR241W MET7 0.69 1.2 Z METhionine requiring
YBR023C CHS3 0.69 1.6 K Required for chitin synthesis. Enzyme responsible for the hyperaccumulation of chitin in response to cell wall stress.
YDL024C DIA3 0.69 3.6 involved in invasive and pseudohyphal growth
YCL032W STE50 0.69 0.8 involved in pheromone signal transduction pathway; interacts with G protein and Ste11p
YDR421W ARO80 0.69 0.9
YDL031W DBP10 0.69 1.4 C Dead box protein 10
YOL062C APM4 0.69 0.8 "Clathrin associated protein, medium subunit"
YNL299W TRF5 0.69 1.0 TRF4 homolog; TRF4/5 function is required for proper mitosis
YML123C PHO84 0.69 2.3 S "inorganic phosphate transporter, transmembrane protein"
YDR310C SUM1 0.69 1.2 Suppresor of mar1-1 (sir2) mutation
YJR160C MPH3 0.69 1.9 "Maltose Permease Homologue. Maltose transporter family member, able to transport hexoses. Capable of transporting maltose, maltotriose, alpha-methylglucoside and turanose."
YGL228W SHE10 0.69 1.0 Mrna (identified by a library screen) that causes growth arrest when overexpressed
YLR427W 0.69 0.8
YBR081C SPT7 0.69 1.0 Transcription factor
YLR219W MSC3 0.69 1.8 Meiotic Sister-Chromatid recombination
YLL045C RPL8B 0.69 1.1 "Homology to human L7a, mouse L7a, rat L7a"
YNL065W AQR1 0.69 1.9 "A(acids, azoles) Q(quinidine, quinine) Resistance"
YAL009W SPO7 0.69 1.2 "dispensable for mitosis, but required for a normal mutation rate, required for premeiotic DNA synthesis, recombination, meiosis I, meiosis II, glycogen degradation and spores"
YAL056W GPB2 0.69 1.5 Gpa2 interacting partner; Homolog of GPB1
Gpb2 binds in the two hybrid system with Gpa2 and plays an inhibitory signaling role attributable to interactions with Gpa2 and an unknown target in the PKA pathway.
YJR036C HUL4 0.69 1.3 ubiquitin-protein ligase (E3)
YOL136C PFK27 0.69 1.9 6-phosphofructo-2-kinase
YPL192C PRM3 0.69 2.9 pheromone-regulated membrane protein
YNL230C ELA1 0.69 1.7 "similar to mammalian elongin A, interacts with elongin C"
YGR211W ZPR1 0.69 0.9 Involved in nucleolar function; similar to murine ZPR1 protein
YNL142W MEP2 0.69 2.0 belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH(4)(+) + NH(3)).
YDL042C SIR2 0.69 1.4 "regulator of silencing at HML, HMR, telomeres, and rDNA"
YIL133C RPL16A 0.69 0.8 Homology to rat L13a
YIL108W 0.69 1.4
YNL209W SSB2 0.69 1.5 stress-seventy subfamily B
YIL170W 0.69 1.3
YBR167C POP7 0.69 1.2 Processing of Precursors
YCR052W RSC6 0.69 1.5 "a subunit of RSC, a fifteen-protein chromatin remodeling complex and related to the swi/snf complex."
YOR017W PET127 0.69 1.4 May be component of mitochondrial translation system with role in promoting accuracy of translational initiation or may play a role in RNA surveillance or RNA processing in mitochondria
YDL070W BDF2 0.69 1.7 "bromodomain protein, homolog of BDF1"
YOL159C 0.69 1.2
YPL105C 0.68 1.3
YDR148C KGD2 0.68 1.1 dihydrolipoyl transsuccinylase component of alpha-ketoglutarate dehydrogenase complex in mitochondria
YOR072W 0.68 1.5
YDR046C BAP3 0.68 2.1 branched-chain amino acid permease
YER126C NSA2 0.68 1.2 Killer toxin Resistant; Nop seven associated protein 2
YKR050W TRK2 0.68 1.3 membrane protein; low affinity potassium transport
YOL138C 0.68 2.2
YIL031W ULP2 0.68 0.9 Peptidase that removes SUMO-conjugates from proteins
YBR207W FTH1 0.68 0.9 FTS3 Homolog 1
YIL050W PCL7 0.68 3.6 Z S C PHO85 cyclin
YDR027C LUV1 0.68 2.1 Loss Upsets Vacuole. Isolated in a microtubule complex containing Rbl2p.
YMR172W HOT1 0.68 1.7 high osmolarity induced transcription
YJR030C 0.68 3.9 S
YBR074W 0.68 1.7
YNR051C BRE5 0.68 1.1 protein of unknown function
YPL019C VTC3 0.68 1.1 Phosphate metabolism; transcription is regulated by PHO system
YGL172W NUP49 0.68 1.3 localizes to discrete spots in the nuclear envelope
YPL118W MRP51 0.68 1.1 Mitochondrial Ribosomal Protein
YMR206W 0.68 1.7
YPR204W 0.68 4.4 S
YDR125C ECM18 0.68 1.9 ExtraCellular Mutant
YLR006C SSK1 0.68 1.3 Two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase)
YOR306C MCH5 0.68 1.5 monocarboxylate permease homologue
YDR081C PDC2 0.68 0.8 "Regulates transcription of PDC1 and PDC5, which encode pyruvate decarboxylase"
YIL082W-A 0.68 0.9
YER076C 0.68 1.0
YGR071C 0.68 1.7
YHL034C SBP1 0.68 1.6 single stranded nucleic acid binding protein
YMR104C YPK2 0.68 1.3 protein kinase
YBL023C MCM2 0.68 4.3 S C Member of complex that acts at ARS's to initiate replication
YGL192W IME4 0.68 2.3 IME4 appears to activate IME1 in response to cell-type and nutritional signals and thereby regulate meiosis
YKR104W 0.68 1.5
YNL117W MLS1 0.68 1.1 carbon-catabolite sensitive malate synthase
YGL129C RSM23 0.68 1.9 mitochondrial ribosome small subunit component
YOR162C YRR1 0.68 1.9 Yeast Reveromycin-A Resistant
YEL036C ANP1 0.68 1.9 "Mannan 8; Protein of the endoplasmic reticulum with a role in retention of glycosyltransferases in the Golgi, also involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol"
YNL151C RPC31 0.68 0.9 31-kDa subunit of RNA polymerase III (C); HMG1 like protein
YMR192W 0.68 1.1
YNL003C PET8 0.68 2.0 S Member of family of mitochondrial carrier proteins
YKR060W 0.68 0.9
YFL048C EMP47 0.68 0.8 47 kDa type I transmembrane protein localized to the Golgi
YHR154W RTT107 0.68 2.7 S C Regulator of Ty1 Transposition; Establishes Silent Chromatin
YDR475C JIP4 0.68 1.8 Jumonji Interacting Protein
YGR131W 0.68 1.4
YNR026C SEC12 0.68 1.3 Required for recruitment of Sar1p and vesicle formation at the endoplasmic reticulum.
YCR005C CIT2 0.68 4.1 C non-mitochondrial citrate synthase
YER050C RSM18 0.68 1.1 protein similar to bacterial ribosomal subunit S18
YJL177W RPL17B 0.68 1.0 "Homology to rat L17, human L17, and E. coli L22"
YDL056W MBP1 0.68 2.7 transcription factor
YPL279C 0.68 1.4
YKL022C CDC16 0.68 1.6 "a component of anaphase-promoting complex required for the G2/M transition in mitosis and degradation of mitotic cyclins, required for sporulation"
YAL019W FUN30 0.68 1.4 Shows homology to SNF2 transcriptional regulator
YGR263C 0.68 1.1
YEL043W 0.68 1.0
YMR309C NIP1 0.68 1.4 "Protein required for nuclear import with some similarity to Nsr1p, another protein involved in nuclear transport"
YFR041C 0.67 1.6
YDR378C LSM6 0.67 0.9 Like Sm-F protein
YOR158W PET123 0.67 1.7 May be component of mitochondrial translation appartus and may interact with small subunit of mitochondrial ribosomes or with Pet122p to promote translational initiation of cytochrome c oxidase subunit III mRNA
YLR312W-A MRPL15 0.67 1.7 Mitochondrial ribosomal protein MRPL15 (YmL15)
YKL171W 0.67 1.4
YOR390W 0.67 1.2
YBR001C NTH2 0.67 1.8 hydrolyzes trehalose; may be inolved in growth transition from glucose to glycerol; shows significant sequence similarity to Nth1p
YDR138W HPR1 0.67 1.2 Hyperrecombination protein that suppresses intrachromosomal excision recombination
YNL309W STB1 0.67 5.1 Z S C binds Sin3p in two-hybrid assay and is present in a large protein complex with Sin3p and Stb2p
YDR122W KIN1 0.67 1.6 Serine/threonine protein kinase
YJL151C SNA3 0.67 0.9 Homology to PMP3/SNA1 (Sensitivity to Na+)
YGR034W RPL26B 0.67 1.0 Homology to rat L26
YPR042C PUF2 0.67 1.8 mRNA binding protein
YGL255W ZRT1 0.67 4.1 S C High-affinity zinc transport protein
YPL078C ATP4 0.67 0.9 ATP synthase F0 sector subunit 4; analogous to the bovine b subunit
YGL012W ERG4 0.67 1.7 Sterol C-24 reductase
YCR021C HSP30 0.67 1.8 "Protein induced by heat shock, ethanol treatment, and entry into stationary phase; located in plasma membrane"
YKL004W AUR1 0.67 3.1 S involved in phospolipid metabolism
YNL118C DCP2 0.67 1.7 Z Mrna Decapping. essential suppressor of the respiratory deficiency of a pet mutant
YFL049W 0.67 1.5
YIL101C XBP1 0.67 1.3 DNA-binding transcriptional repressor
YPL237W SUI3 0.67 1.0 eIF2 is a heterotrimeric GTP-binding protein
SUI2 encodes the alpha subunit
GCD11 encodes the gamma subunit
YFL021W GAT1 0.67 1.4 activator of transcription of nitrogen-regulated genes; inactivated by increases in intracellular glutamate levels
YPL250C ICY2 0.67 2.4 S Interacting with the cytoskeleton
Involved in chromatin organization and nuclear transport
Genetically interacts with TCP1 and ICY1
YGL135W RPL1B 0.67 1.5 "Homology to rat L10a, eubacterial L1, and archaebacterial L1; identical to S. cerevisiae L1A (Ssm1p)"
YPL220W RPL1A 0.67 1.4 "Homology to rat L10a, eubacterial L1, and archaebacterial L1; identical to S. cerevisiae L1B (Ssm2p)"
YKR061W KTR2 0.67 1.9 May be involved in extracellular matrix assembly; involved in N-linked glycosylation of cell wall mannoproteins
YGL013C PDR1 0.67 2.3 general positive regulator of permeability genes
YBR146W MRPS9 0.67 1.2 Probable mitochondrial ribosomal protein S9
YLR411W CTR3 0.67 1.0 integral membrane protein that functions in high affinity copper transport
YDR249C 0.67 2.0
YNL215W IES2 0.67 1.3 Hypothetical ORF
YBR060C ORC2 0.67 1.3 origin recognition complex subunit 2
YJR153W PGU1 0.67 2.2 Endo-polygalacturonase
YDR462W MRPL28 0.67 0.9 Mitochondrial ribosomal protein MRPL28 (YmL28)
YER116C SLX8 0.67 0.9
YOR221C MCT1 0.67 1.5 malonyl-CoA:ACP transferase
YLR030W 0.67 2.3
YGL146C 0.67 2.4
YOR244W ESA1 0.67 1.0 contains amino-terminal chromodomains; Essential SAS family Acetyltransferase sharing homology with acetyltransferases from many different organisms
YGL263W COS12 0.67 1.5 "Protein with strong similarity to subtelomerically-encoded proteins including Cos2p, Cos4p, Cos8p, YIR040c, Cos5p, Cos9p, and Cos6p"
YDR104C SPO71 0.67 0.9 Product of gene unknown
YPL084W BRO1 0.67 1.0 BCK1-like resistance to osmotic shock
YGL212W VAM7 0.67 2.4 S Regulator of vacuolar morphogenesis
YER019W ISC1 0.67 2.7 S C
YHR151C 0.67 3.3 S C
YGR196C FYV8 0.67 0.8 Function required for Yeast Viability on toxin exposure
YKR001C VPS1 0.67 1.8 C involved in vacuolar protein sorting and normal organization of intracellular membranes; probably required for membrane-protein retention in a late Golgi compartment
YIL154C IMP2' 0.67 0.8 "Protein involved in nucleo-mitochondrial control of maltose, galactose and raffinose utilization"
YDR128W 0.67 1.0
YGR140W CBF2 0.67 2.9 Z S C "110 kd component (Cbf3a) of the multisubunit 'Cbf3' kinetochore protein complex, which binds to the CDE III element of centromeres"
YJL212C OPT1 0.67 2.0 "Oligopeptide transporter; Opt1p transports tetra- and pentapeptides, including the endogenous opioid pentapeptide leucine enkephalin."
YPL162C 0.67 2.5
YPL008W CHL1 0.67 1.6 "Required for mitotic chromosome segregation, needed for wild-type levels of meiotic recombination and spore viability"
YGL238W CSE1 0.67 1.4 Protein required for accurate mitotic chromosome segregation
YMR073C 0.67 0.8
YPR078C 0.67 2.4
YDL248W COS7 0.67 1.3 "Protein with strong similarity to other subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YDL195W SEC31 0.67 1.4 involved in protein transport from endoplasmic reticulum to Golgi
YGR097W ASK10 0.67 0.8 transcriptional activator of the SKN7 mediated 'two-component' regulatory system
YML008C ERG6 0.67 1.8 ergosterol synthesis
YOR243C PUS7 0.67 1.4 Pseudouridine Synthase
YAL022C FUN26 0.67 3.8 S C predicted membrane protein
YKL088W 0.67 1.0
YDR282C 0.67 1.7
YFL013C IES1 0.66 0.9 Hypothetical ORF
YNL294C RIM21 0.66 1.2 Regulator of IME2
YPR097W 0.66 1.1
YMR006C PLB2 0.66 2.9 Phospholipase B 2
YER148W SPT15 0.66 0.9 TATA-binding protein (TBP)
YGL184C STR3 0.66 4.9 S Sulfur TRansfer
YGR128C UTP8 0.66 1.0 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YOL004W SIN3 0.66 1.1 DNA binding protein involved in transcriptional regulation
YER013W PRP22 0.66 1.1 helicase-like protein
YLL034C 0.66 1.7
YNL212W VID27 0.66 1.8 Vacuole import and degradation
YDL176W 0.66 1.6
YOR270C VPH1 0.66 1.8 S vacuolar ATPase V0 domain subunit a (100 kDa)
YBL052C SAS3 0.66 3.4 Z S C "SAS3 for Something about silencing, gene 3. Influences silencing at HMR."
YLR047C 0.66 2.4
YHL004W MRP4 0.66 1.3 Involved in mitochondrial protein synthesis
YLR356W 0.66 1.0
YOR291W 0.66 0.9
YOL041C NOP12 0.66 1.5 Nucleolar Protein; isolated as a mutant exhibiting synthetic lethality with a nop2 ts allele.
YBL047C EDE1 0.66 0.8 EH domain protein involved in endocytosis
YGL180W APG1 0.66 1.5 Required for autophagy
YOL082W CVT19 0.66 1.8 Cytoplasm to Vacuole Targeting; Mutant is defective in import of aminopeptidase I through the cytoplasm to vacuole targeting pathway
YAL051W OAF1 0.66 1.0 transcription factor
YLR189C UGT51 0.66 1.3 Udp-glycosyltransferase
YBR180W DTR1 0.66 1.6 dityrosine transporter MFS-MDR
YOR138C 0.66 1.5
YHR152W SPO12 0.66 3.0 K S C Thought to be a positive regulator of exit from M-phase in mitosis and meiosis; interacts with Dbf2p and Dbf20p protein kinases
YDL247W MPH2 0.66 1.8 "Maltose Permease Homologue. Maltose transporter family member, able to transport hexoses. Capable of transporting maltose, maltotriose, alpha-methylglucoside and turanose."
YGL064C MRH4 0.66 1.1 mitochondrial RNA helicase
YJR126C VPS70 0.66 1.3
YIL156W UBP7 0.66 1.1 Ubiquitin-specific protease
YLR430W SEN1 0.66 1.3 component of a nuclear-localized tRNA splicing complex
YLR256W HAP1 0.66 1.8 Activator of CYC1 and CYP3 transcription; positive regulator of cytochrome C genes CYC1 and CYC7
YLR130C ZRT2 0.66 1.2 Low-affinity zinc transport protein
YJL216C 0.66 2.7
YGR106C 0.66 1.4
YDR065W 0.66 1.1
YDR466W 0.66 1.1
YOL125W 0.66 1.4
YML100W TSL1 0.66 3.2 S 123 kD regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex; homologous to TPS3 gene product
YGL166W CUP2 0.66 1.4 Upregulates metallothionein (CUP1) expression in response to Cu2+
YPL207W 0.66 1.7
YGR090W UTP22 0.66 1.4 U3 protein
YNL127W 0.66 1.2
YDR492W 0.66 2.1
YMR136W GAT2 0.66 2.0 Similar to GATA-family of DNA binding proteins
YMR308C PSE1 0.66 1.1 Functions in nuclear transport of proteins
YGL163C RAD54 0.66 3.6 K S "Required for X-ray damage repair, mitotic recombination, and full meiotic recombination. mRNA increases in meiosis."
YML111W BUL2 0.66 0.9 a homologue of BUL1
YBR075W 0.66 1.5
YGL098W USE1 0.66 1.4 Protein required for cell viability
YJL165C HAL5 0.66 1.3 "Protein kinase homolog, mutant is salt and pH sensitive"
YIR004W DJP1 0.66 1.1 DnaJ-like protein required for Peroxisome biogenesis; Djp1p is located in the cytosol
YGR273C 0.66 2.5
YER060W FCY21 0.66 1.2 identical to FCY2
YOR337W TEA1 0.66 2.4 S Mutants are defective in Ty1 Enhancer-mediated Activation
YBR157C ICS2 0.66 4.6 S C Increased Copper Sensitivity
YGR258C RAD2 0.66 2.4 "Incision step of nucleotide excision repair of DNA damaged by UV light; co-purifies with transcription factor, TFIIH mRNA is cell cycle regulated & induced by DNA damage & by meiosis"
YGR295C COS6 0.66 1.9 "Protein with strong similarity to other subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YGL124C MON1 0.66 1.1 Product of gene unknown
YDR233C RTN1 0.65 1.3 reticulon gene member of the RTNLA (reticulon-like A) subfamily
YGR147C NAT2 0.65 0.9 Transfers acetyl group from acetyl coenzyme A to the N-termini of proteins beginning with methionine
YOR152C 0.65 3.1 S
YGL140C 0.65 1.6
YHL020C OPI1 0.65 1.3 Negative regulator of phospholipid biosynthesis
YDR299W BFR2 0.65 1.3 involved in protein transport step at the Brefeldin A blocks
YHR055C CUP1-2 0.65 2.4 required for cell growth at high copper concentrations.
YHR053C CUP1-1 0.65 2.5 required for cell growth at high copper concentrations.
YNL125C ESBP6 0.65 2.2 Protein with similarity to mammalian monocarboxylate transporters MCT1 and MCT2
YNL072W RNH35 0.65 3.5 S C "RNase H(35), a 35 kDa ribonuclease H"
YDR518W EUG1 0.65 2.4 ER protein functionally likely involved in interacting with nascent polypeptides in the ER
YOL077C BRX1 0.65 1.2 Essential nucleolar protein required for biogenesis of the 60S ribosomal subunit
YPR031W NTO1 0.65 2.6 NuA3 ORF 1
YLR298C YHC1 0.65 0.8 U1 snRNP protein required for pre-mRNA splicing
YJL181W 0.65 4.2 Z S C
YBR132C AGP2 0.65 1.3 "The acronym may be misleading. AGP2 has been shown to be a carnitine permease, not a general amino acid permease with broad substrate specificity."
YFL023W BUD27 0.65 1.1 Function required for yeast viability on toxin exposure
YJR120W 0.65 1.0
YKL012W PRP40 0.65 1.4 Splicing component that associates with the yeast U1 small nuclear ribonucleoprotein particle
YDL156W 0.65 3.5 Z S C
YGL207W SPT16 0.65 3.2 Z S global regulator of transcription
YER017C AFG3 0.65 0.9 C ATPase family gene
YNL221C POP1 0.65 1.1 Required for processing of pre-tRNAs and the 5.8S rRNA precursor
YGR222W PET54 0.65 2.0 translational activator of cytochrome c oxidase subunit III; required for splicing of cytochrome c oxidase subunit I mRNA
YHR127W 0.65 2.6 S
YMR223W UBP8 0.65 1.3 putative deubiquitinating enzyme
YBL111C 0.65 4.0 S
YFL012W 0.65 2.3
YNL064C YDJ1 0.65 1.3 yeast dnaJ homolog (nuclear envelope protein); heat shock protein
YFL062W COS4 0.65 1.3 "Protein with strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YHR090C YNG2 0.65 0.9 Yeast homolog of mammalian Ing1
YMR098C 0.65 1.4
YGL176C 0.65 1.2
YJL023C PET130 0.65 1.3 Nuclear gene encoding mitochondrial protein
YNL271C BNI1 0.65 0.9 Protein involved in cytoskeletal control and required for proper bipolar budding pattern; interacts with Rho1p
YKR096W 0.65 1.0
YPL254W HFI1 0.65 1.3 Transcription factor involved in global regulation of gene expression
YML117W 0.65 1.7 S
YIL105C 0.65 2.2
YFR032C 0.65 1.3
YFR014C CMK1 0.65 2.7 Calmodulin-dependent protein kinase
YFR001W LOC1 0.65 0.8 Localization of mRNA
YHR020W 0.65 1.3
YNL263C YIF1 0.65 3.2 S "Yip1-Interacting Factor, shows similarity to NADH dehydrogenases"
YDL113C CVT20 0.65 2.5 Cytoplasm to vacuole targeting
YKR009C FOX2 0.65 1.6 peroxisomal multifunctional beta-oxidation protein
YDR090C 0.65 0.9
YDL140C RPO21 0.65 0.8 RNA polymerase II large subunit
YBR222C FAT2 0.65 1.9 "Fatty acid transporter, very similar to FAT1"
YLR383W RHC18 0.65 4.6 Z S C "Protein involved in recombination repair, homologous to S. pombe rad18. Structural maintenance of chromosomes (SMC) protein."
YLR197W SIK1 0.65 1.3 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); similar to microtubule binding proteins and to X90565_5.cds
YIL112W 0.65 1.4
YPR104C FHL1 0.65 2.7 Putative transcriptional regulator of rRNA-processing genes
YER020W GPA2 0.65 2.2 homologous to mammalian G proteins; potential role in regulation of cAMP levels
YGR053C 0.65 2.2
YHR072W ERG7 0.65 1.4 carries out complex cyclization step of squalene to lanosterol in sterol biosynthesis pathway
YNL277W MET2 0.65 1.9 "catalyzes the conversion of homoserine to O-acetyl homoserine which in turn combines with hydrogen sulfide to form homocysteine, the immediate precursor of methionine"
YOR165W SEY1 0.65 1.8 Z Synthetic Enhancement with YOP1
YMR010W 0.65 1.1
YMR021C MAC1 0.65 0.9 metal-binding transcriptional activator
YDL005C MED2 0.65 1.1 RNA Polymerase II transcriptional regulation mediator
YLR466W YRF1-4 0.65 4.3 Z S Y'-helicase protein 1
YNR075W COS10 0.65 1.4 "Protein with strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YIR011C STS1 0.65 1.1 restores protein transport when overexpressed and rRNA stability to a sec23 mutation
YOR166C 0.65 0.8
YDL073W 0.65 1.4
YKR078W 0.65 1.4
YJL036W SNX4 0.65 1.2 Sorting NeXin
YGL226C-A OST5 0.65 1.5 Oligosaccharyltransferase catalyzes the transfer of oligosaccharide from a dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synthesized proteins in ER lumen
YBR299W MAL32 0.65 1.8 Part of the complex locus MAL3; functional in S288C; highly homologous to MAL62 from S. carlsbergenesis strain CB11
YOL137W 0.65 1.6 C
YPL058C PDR12 0.64 3.0 S C similar to Pdr5p
YGL077C HNM1 0.64 1.5 choline transport protein; may also control uptake of nitrogen mustard
YCR094W CDC50 0.64 1.3 cell division cycle mutant
YOR160W MTR10 0.64 1.5 Protein involved in mRNA transport from nucleus to cytoplasm
YLR147C SMD3 0.64 0.9 involved in snRNP biogenesis and pre-mRNA splicing
YDL198C YHM1 0.64 2.3 C high copy suppressor of abf2 lacking the HMG1-like mitochondrial HM protein; putative mitochondrial carrier protein
YPR175W DPB2 0.64 5.9 K Z S C "DNA polymerase epsilon, subunit B"
YNR018W 0.64 1.5
YNL201C PSY2 0.64 1.1 Platinum Sensitivity
YDL150W RPC53 0.64 1.1 "RNA polymerase III (C) subunit, homologus to human BN51 protein"
YFL014W HSP12 0.64 2.5 "induced by heat shock, entry into stationary phase, depletion of glucose, and addition of lipids (fatty acids)"
YOL083W 0.64 2.5
YNL251C NRD1 0.64 1.8 RNA recognition motif-containing protein that participates in sequence-specific regulation of nuclear pre-mRNA abundance
YHR218W 0.64 5.2 Z S
YDR016C DAD1 0.64 2.1 Duo1 And Dam1 interacting; localized to intranuclear spindles and spindle pole bodies
YMR252C 0.64 1.3
YDR001C NTH1 0.64 2.1 S hydrolyzes trehalose; may be inolved in growth transition from glucose to glycerol; shows significant sequence similarity to Nth2p
YDR005C MAF1 0.64 1.8 Mod5 protein sorting. Negative effector of Pol III synthesis.
YLR350W ORM2 0.64 1.0 Homologous to ORM1.
YOL047C 0.64 1.3
YPR112C MRD1 0.64 1.8 Multiple RNA Binding Domain; essential for synthesis of the small ribosomal subunit
YLR173W 0.64 1.6
YPR192W AQY1 0.64 1.5 Aquaporin
YBL098W BNA4 0.64 2.4 S Biosynthesis of Nicotinic Acid
YLR212C TUB4 0.64 3.7 S C spindle pole body component that organizes both cytoplasmic and nuclear microtubule arrays
YDL079C MRK1 0.64 1.4 putative protein kinase with similarity to mammalian glycogen synthase kinase-3 and Drosophila Zeste-White3/Shaggy
YJR052W RAD7 0.64 0.8 Nucleotide excision repair protein involved in G(sub)2 repair of inactive genes
YGR292W MAL12 0.64 2.5 Part of the complex locus MAL1; functional in S288C
YJR035W RAD26 0.64 1.6 May be involved in transcription-coupled DNA repair
YBL074C AAR2 0.64 1.5 splices pre mRNA of the MATa1 cistron
YJL093C TOK1 0.64 1.6 Target Of K1 Killer Toxin
YHL008C 0.64 2.2
YLR098C CHA4 0.64 1.4 S Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain
YMR260C TIF11 0.64 1.2 Translation initiation factor eIF1A
YPL062W 0.64 2.7
YGL092W NUP145 0.64 0.8 Nuclear pore complex protein with GLFG motif
YDR105C 0.64 1.2
YGR287C 0.64 0.8
YIL099W SGA1 0.64 1.6 "intracellular sporulation-specific glucoamylase involved in glycogen degradation. Induced during starvation of a/a late in sporulation, but dispensable for sporulation"
YOR145C 0.64 1.3
YDL181W INH1 0.64 1.7 C ATPase inhibitor
YJR147W HMS2 0.64 1.8 High-copy mep2 suppressor
YDL207W GLE1 0.64 1.6 Polyadenylated-RNA-export factor; the HIV Rev protein may mimic function of Gle1
YIL005W EPS1 0.64 1.0
YOR118W 0.64 0.8
YPL179W PPQ1 0.64 1.4 May play role in regulation of translation
YMR018W 0.64 1.4
YPL132W COX11 0.64 2.3 Mitochondrial membrane protein required for insertion of Cu(B) and magnesium during assembly of cytochrome c oxidase
YBL104C 0.64 1.2
YPR179C PLO1 0.64 1.2 Ploidy-related. Nuclear protein
YPL187W MF(ALPHA)1 0.64 3.2 S C mating factor alpha
YMR024W MRPL3 0.64 1.1 Mitochondrial ribosomal protein MRPL3 (YmL3)
YLR078C BOS1 0.64 0.8 necessary for vesicular transport from the ER to the Golgi complex
YKL187C 0.64 1.6
YKL033W 0.64 1.2
YIL132C CSM2 0.64 3.3 Z S Chromosome segregation in meiosis
YKL180W RPL17A 0.64 1.0 "Homology to rat L17, human L17, and E. coli L22"
YLR278C 0.63 1.7
YGR142W BTN2 0.63 1.3 Gene/protein whose expression is elevated in a btn1 minus/Btn1p lacking yeast strain.
YPR202W 0.63 4.1 Z S
YIL088C 0.63 1.4
YOR232W MGE1 0.63 1.0 involved in protein import into mitochondria
YER082C UTP7 0.63 1.6 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YDR508C GNP1 0.63 1.7 high-affinity glutamine permease
YOL066C RIB2 0.63 0.9 Riboflavin biosynthesis
YBL032W HEK2 0.63 3.9 Z C Heterogeneous nuclear RNP K-like gene
YGL078C DBP3 0.63 1.2 ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family
YDR314C 0.63 2.6
YOL157C 0.63 0.9
YKL051W 0.63 1.5
YDR334W SWR1 0.63 1.6 Sick With RSC
YHR120W MSH1 0.63 1.3 mutS homolog involved in mitochondrial DNA repair
YOL022C 0.63 1.0
YNL169C PSD1 0.63 1.7 S Converts phosphatidylserine to phosphatidylethanolamine. Mitochondrial Psd1p provides ~90% of total cellular phosphatidylserine decarboxylase activity.
YKL145W RPT1 0.63 1.2 Required for degradation of ubiquitinated substrates and for anaphase chromosome separation
YKL015W PUT3 0.63 1.2 Positive regulator of PUT (proline utilization) genes
YOR092W ECM3 0.63 1.4 ExtraCellular Mutant
YIL120W QDR1 0.63 1.7 Quinidine Resistance
YGR059W SPR3 0.63 2.3 a sporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilament genes; regulated by ABFI
YAL033W POP5 0.63 1.2 Processing Of Precursors - refer to a group of proteins that appear to be components of both RNase P and RNase MRP
YNL061W NOP2 0.63 1.5 May participate in nucleolar function during the transition from stationary phase to rapid growth
YHR056C RSC30 0.63 1.3 RSC complex component
YHR108W GGA2 0.63 2.0 S "Golgi-localized, gamma-adaptin homology, Arf-binding. Interacts with Arf1p and Arf2p in a GTP-dependent manner. Effector of Arf that facilitates traffic through the late Golgi."
YML081W 0.63 1.3
YNR028W CPR8 0.63 2.5 Z Shows similarity to the secretory pathway cyclophilin Cpr4
YGR188C BUB1 0.63 4.5 Z S checkpoint gene involved in permitting entry into mitosis depending upon the assembly state of microtubules
YLR144C ACF2 0.63 0.8 Identified as an activity necessary for actin polymerization in permeabilized cells
YFR031C SMC2 0.63 0.9 Chromosome segregation and condensation
YOR112W 0.63 1.9 Z
YGL006W PMC1 0.63 0.8 May be involved in depleting cytosol of Ca2+ ions
YFL031W HAC1 0.63 1.5 Transcription factor that is required for the unfolded protein-response pathway; binds to CRE motif; homologous to ATF/CREB 1
YIR002C MPH1 0.63 1.7 Mutator PHenotype; Similar to ATP-dependent RNA helicases
YHR168W 0.63 1.3
YGR149W 0.63 1.7
YMR135C DCR1 0.63 1.7 Dose-dependent Cell cycle Regulator
YPL135W ISU1 0.63 2.3 Iron-sulfur cluster nifU-like protein
YLR220W CCC1 0.63 1.0 Functions in the homeostasis of both calcium and manganese ions
YER060W-A FCY22 0.63 2.2 identical to FCY2
YHR192W 0.63 0.8
YJR002W MPP10 0.63 1.4 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YHR204W MNL1 0.63 1.6 mannosidase like
YLR392C 0.63 1.3
YDR497C ITR1 0.63 1.6 member of sugar transporter superfamily
YKL126W YPK1 0.63 1.2 "76.5 kDa Serine/threonine protein kinase with similarity to protein kinase C, is 90% identical to Ypk2p"
YDR182W CDC1 0.63 1.2 "Protein that affects bud emergence, intrachromosomal recombination, and nuclear division"
YJL131C 0.63 1.0
YJL041W NSP1 0.63 0.8 Nucleoskeletal protein found in nuclear pores and spindle pole body
YDR292C SRP101 0.63 1.0 signal recognition particle receptor - alpha subunit
YOL087C 0.63 1.1
YMR319C FET4 0.63 1.6 Putative transmembrane low-affinity Fe(II) transporter
YKL109W HAP4 0.63 2.6 Regulates respiratory functions; encodes divergent overlapping transcripts
YGL099W LSG1 0.63 1.3 Killer toxin REsistant
YCR011C ADP1 0.63 1.4 Shows homology to ATP-dependent permeases
YOR057W SGT1 0.63 0.8 G2 allele of skp1 suppressor; subunit of SCF ubiquitin ligase complex; essential regulator of cell cycle; essential component of kinetochore assembly pathway.
YLR397C AFG2 0.63 1.2 ATPase family gene
YGL038C OCH1 0.63 3.7 S initiates the polymannose outer chain elongation of N-linked glycans
YLR418C CDC73 0.63 1.6 accessory factor associated with RNA polymerase II by affinity chromatography
YMR156C TPP1 0.63 1.5 Three Prime Phosphatase 1
YNL336W COS1 0.63 1.0 "Protein with similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p"
YOR108W 0.63 1.3
YDR118W APC4 0.63 0.8 subunit of the Anaphase Promoting Complex; all known APC subunits co-immunoprecipitate with epitope-tagged Apc4p
YPL011C TAF3 0.63 0.9 TAF(II) complex (TBP-associated protein complex) component
YPR045C 0.63 2.2 S
YJL034W KAR2 0.63 2.0 Involved in translocation of nascent polypeptides across the ER membrane
YJL094C KHA1 0.63 1.4 putative K+/H+ antiporter
YOR249C APC5 0.63 1.1 subunit of the Anaphase Promoting Complex; all known APC subunits co-immunoprecipitate with epitope-tagged Apc5
YHR142W CHS7 0.63 1.1 The seventh gene identified that is involved in chitin synthesis; involved in Chs3p export from the ER
YNR050C LYS9 0.63 2.3 S Seventh step in lysine biosynthesis pathway
YJL098W SAP185 0.63 1.1 "SIT4 associated protein, MW of 185 kDa"
YIL109C SEC24 0.63 1.0 The Sec23p-Sec24p complex is one of three cytoplamic COPII factors involved in ER to Golgi transport
YKR028W SAP190 0.63 1.1 190 kDa protein that associates with the SIT4 phosphatase in a cell cycle dependent manner
YPL156C PRM4 0.62 1.9 pheromone-regulated membrane protein
YBL066C SEF1 0.62 1.9 Suppressor of Essential Function
YCR065W HCM1 0.62 4.8 Z S C Dosage-dependent suppressor of cmd1-1 mutation; shows homology to fork head family of DNA-binding proteins
YBR031W RPL4A 0.62 3.4 "Homology to rat L4, Xenopus L1, Drosophila L1"
YBL056W PTC3 0.62 1.1 protein phosphatase type 2C
YHR038W FIL1 0.62 1.9 C Putative mitochondrial ribosome recycling factor
YHR061C GIC1 0.62 5.1 Z S C Gtpase-interacting component 1
YGL160W 0.62 1.2
YGR146C 0.62 2.7 S
YDL240W LRG1 0.62 2.2 Expressed most highly in sporulating cells; may also play a role during mating
YMR269W 0.62 1.9
YBL075C SSA3 0.62 0.8 heat-inducible cytosolic member of the 70 kDa heat shock protein family
YNL250W RAD50 0.62 1.3 "coiled-coil protein, contains a purine-binding domain, two heptad repeats and a hydrophobic tail"
YER056C FCY2 0.62 0.9 purine-cytosine permease
YOR368W RAD17 0.62 1.6 K DNA Damage checkpoint control
YLR154C 0.62 3.2 S
YGL027C CWH41 0.62 3.4 S C "Glucosidase I, involved in assembly of cell wall beta 1,6 glucan; an ER type II integral membrane N-glycoprotein"
YER079W 0.62 2.1
YDR530C APA2 0.62 1.9 "5',5'''-P-1,P-4-tetraphosphate phosphorylase II"
YDR012W RPL4B 0.62 2.6 Highly similar to ribosomal protein L4A
YLR056W ERG3 0.62 3.4 Z S C-5 sterol desaturase
YIL172C 0.62 2.1
YJR095W SFC1 0.62 1.2 succinate-fumarate carrier
YDL049C KNH1 0.62 1.5 46% identical at amino acid level to Kre9p; located extracellularly
YJL221C FSP2 0.62 1.0 homology to maltase(alpha-D-glucosidase)
YDR482C CWC21 0.62 1.4 Complexed With Cef1p
YDR119W 0.62 1.0
YHL019C APM2 0.62 1.2 homologous to the medium chain of mammalian clathrin-associated protein complex
YDL087C LUC7 0.62 1.0 Living Under Cap-binding complex expression
YOR083W WHI5 0.62 2.6 S whiskey (whi) mutant
YML059C 0.62 1.0
YDR173C ARG82 0.62 0.9 Regulator of arginine-responsive genes with ARG80 and ARG81
YFR019W FAB1 0.62 1.0 May regulate vacuole homeostasis; mutation causes pleiotropic effects on nuclear migration and orientation and separation of mitotic chromosomes
YCR045C 0.62 1.2
YLR022C 0.62 1.3
YMR091C NPL6 0.62 0.9 involved in nuclear protein targeting
YLR239C LIP2 0.62 1.6 LIPoyl ligase 2
YDR477W SNF1 0.62 1.1 "Required for release from glucose repression, invertase expression, and sporulation. Required for expression of catabolite-repressed genes when glucose is limiting."
YLL001W DNM1 0.62 1.4 Involved in receptor-mediated endocytosis and mitochondrial organization. Required for the cortical distribution of the mitochondrial network.
YLR160C ASP3-4 0.62 1.0 nitrogen catabolite-regulated cell-wall L-asparaginase II
YLR157C ASP3-2 0.62 1.2 nitrogen catabolite-regulated cell-wall L-asparaginase II
YLR155C ASP3-1 0.62 1.2 nitrogen catabolite-regulated cell-wall L-asparaginase II
YLR158C ASP3-3 0.62 0.9 nitrogen catabolite-regulated cell-wall L-asparaginase II
YPR003C 0.62 1.1
YKL155C RSM22 0.62 0.9 mitochondrial ribosome small subunit component
YLR032W RAD5 0.62 2.8 S C putative ATPase/DNA helicase
YHR109W CTM1 0.62 2.1 cytochrome c trimethylase
YOR209C NPT1 0.62 0.9 homology to bacterial nicotinate phosphoribosyl transferase; NAD(+) salvage pathway
YLL006W MMM1 0.62 2.0 Involved in mechanism by which mitochondrial shape is established or maintained
YMR219W ESC1 0.62 1.4 Establishes Silent Chromatin
YKL135C APL2 0.62 1.0 "Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex"
YBR095C RXT2 0.62 1.2 Hypothetical ORF
YBR020W GAL1 0.62 1.0 Haploid specific protein localized in the Golgi and plasma membrane
YLR362W STE11 0.62 1.0 involved in the mating signalling pathway
YGR093W 0.62 0.8
YER124C DSE1 0.62 6.7 S Daughter Specific Expression 1
YJL184W 0.62 0.8
YJR064W CCT5 0.62 0.8 Required for assembly of microtubules and actin in vivo
YIL142W CCT2 0.62 0.8 cytoplasmic chaperonin of the Cct ring complex related to Tcp1p; subunit beta
YJR015W 0.62 1.6
YJL140W RPB4 0.62 1.2 fourth-largest subunit of RNA polymerase II
YMR160W 0.62 1.1
YGL079W 0.62 1.3
YGL241W KAP114 0.62 1.4 KAryoPherin (collective name for homologous family of nuclear transport receptors) of approximately 114kD
YDR440W DOT1 0.62 2.8 S involved in meiosis and transcriptional silencing
YAL007C ERP2 0.62 2.3 Emp24p/Erv25p related protein 2
YER190W YRF1-2 0.62 4.8 S C Y'-helicase protein 1
YKR022C 0.62 0.9
YGR127W 0.62 1.2
YGL014W PUF4 0.62 1.6 member of the PUF protein family
YDL227C HO 0.62 4.1 K S C Homothallic switching
YPR007C SPO69 0.62 1.6 Required for sporulation; highly induced during sporulation.
YPL109C 0.62 1.3
YHR050W SMF2 0.62 1.9 SMF2 was isolated as a high copy suppressor of a temperature sensitive mutation in the PEP ( mitochondrial matrix protease) gene and may influence PEP-dependent protein import
YHR027C RPN1 0.62 1.0 Subunit of 26S Proteasome (PA700 subunit)
YCL054W SPB1 0.62 1.4 Suppressor of PaB1 mutant; involved in 60S ribosomal subunit biogenesis
YLR001C 0.62 1.4
YML072C 0.62 2.8 Z S
YHR197W IPI2 0.62 1.1 Involved in Processing ITS2
YNL049C SFB2 0.62 1.5 binds to Sed5p and Sec23p by distinct domains
YBR068C BAP2 0.62 2.3 contains 12 predicted transmembrane domains
YKL062W MSN4 0.62 2.0 Transcription factor. Multicopy suppressor of snf1 mutation. Key regulator of stress-responsive gene expression.
YNR055C HOL1 0.62 1.8 Z Putative ion transporter similar to the major facilitator superfamily of transporters
YBL063W KIP1 0.62 3.8 S C Mitotic spindle assembly
YDR093W DNF2 0.62 1.5 Drs2 Neo1 Family
YLR152C 0.62 1.9
YDL202W MRPL11 0.62 1.2 Mitochondrial ribosomal protein MRPL11 (YmL11)
YLR027C AAT2 0.62 1.5 "aspartate aminotransferase, cytosolic"
YNL130C CPT1 0.62 1.7 Phospholipid biosynthesis
YDR168W CDC37 0.62 1.0 cell cycle protein necessary for passage through START
YDR342C HXT7 0.62 2.5 S Hexose transporter
YER177W BMH1 0.62 0.8 Brain Modulosignalin Homolog
YMR043W MCM1 0.62 0.9 Involved in cell-type-specific transcription and pheromone response
YNL321W 0.62 1.5
YDR338C 0.62 1.1
YJR119C 0.62 1.2
YHL017W 0.62 1.1
YPL005W 0.61 2.0
YBR257W POP4 0.61 1.6 Required for normal 5.8S rRNA processing and for tRNA processing; associated with RNase MRP and RNase P
YOR035C SHE4 0.61 1.8 Required for mother cell-specific HO expression
YGR270W YTA7 0.61 1.2 Member of CDC48/PAS1/SEC18 family of ATPases
YLR234W TOP3 0.61 3.2 S C DNA Topoisomerase III
YNL083W 0.61 1.0
YBL029W 0.61 1.7
YKL201C MNN4 0.61 1.4 Required for the transfer of mannosylphosphate to cell wall mannans.
YDR253C MET32 0.61 1.6 Involved in methionine metabolism
YKL100C 0.61 1.4
YNR059W MNT4 0.61 1.5 MaNnosylTransferase
YNR056C BIO5 0.61 1.6 transmembrane regulator of KAPA/DAPA transport
YPR029C APL4 0.61 2.0 "Gamma-adaptin, large subunit of the clathrin-associated protein (AP) complex"
YGR179C OKP1 0.61 2.0 Outer Kinetochore Protein
YOR007C SGT2 0.61 1.7 small glutamine-rich tetratricopeptide repeat containing protein
YHR189W 0.61 2.1
YPL249C GYP5 0.61 1.1 GAP for Ypt protein
YJR143C PMT4 0.61 2.1 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway
YGR245C SDA1 0.61 1.4 Severe Depolymerization of Actin
YCL036W GFD2 0.61 1.3 Great for FULL DEAD box protein activity
YOR062C 0.61 1.3
YDR052C DBF4 0.61 1.4 K Required for Cdc7 kinase activity
YKL046C DCW1 0.61 1.5 Defective Cell Wall
YGL128C CWC23 0.61 0.9 Complexed with Cef1p
YKL090W CUE2 0.61 2.2 Hypothetical ORF
YDL091C 0.61 1.1
YOR140W SFL1 0.61 1.1 Transcription factor with domains homologous to myc oncoprotein and yeast Hsf1p required for normal cell surface assembly and flocculence
YLR328W NMA1 0.61 0.8 NAD(+) salvage pathway
YEL054C RPL12A 0.61 1.3 Homology to rat L12(a) and E. coli L11
YDR418W RPL12B 0.61 2.4 Homology to rat L12(a) and E. coli L11
YCR066W RAD18 0.61 0.9 "Zn finger protein, putative ATPase"
YDL138W RGT2 0.61 3.0 S C glucose permease
YOR191W RIS1 0.61 1.3 Role in silencing
YAL035W FUN12 0.61 1.0 Functions in general translation initiation by promoting Met-tRNAiMet binding to ribosomes.
YGR032W GSC2 0.61 1.5 "Highly similar to FKS1 (GSC1). GSC2 and FKS1 encode redundant catalytic components of 1,3-beta-glucan synthase. Deletion of both is lethal"
YLR107W REX3 0.61 1.0 RNA EXonuclease; member of 3'->5' exonuclease family. See Moser et al. 1997 Nucleic acids Res. 25:5110-5118
YLL022C HIF1 0.61 4.9 Z S C Hat1 Interacting Factor 1
YHL038C CBP2 0.61 0.8 Protein required for splicing of COB aI5 intron
YJR093C FIP1 0.61 1.2 component of a pre-mRNA polyadenylation factor that interacts with poly(A) polymerase
YOL122C SMF1 0.61 1.5 Isolated as high copy suppressor of a cdc1 mutation & involved in high affinity Mn2+ uptake. SMF1 was isolated as a high copy suppressor of a ts mutation in the PEP (mito. matrix protease) gene & may influence PEP-dependent protein import
YFR046C 0.61 1.6
YOR099W KTR1 0.61 2.2 Z mannosyltransferase involved in O- and N-linked glycosylation
YJL134W LCB3 0.61 2.9 Z S Protein involved in incorporation of exogenous long chain bases in sphingolipids
YCL051W LRE1 0.61 1.0 involved in laminarase resistance
YNL178W RPS3 0.61 1.1 "Homology to mammalian S3. The AP endonuclease activity of Rps3p is affected by pH, KCl, and beta-mercaptoethanol, but not Triton X-100 or EDTA."
YGR195W SKI6 0.61 1.0 superkiller; ExtraCellular Mutant; Ribosomal RNA Processing
YGL158W RCK1 0.61 1.8 Serine/threonine protein kinase
YNL137C NAM9 0.61 1.4 putative mitochondrial S4 ribosomal protein
YIL177C 0.61 4.4 Z S
YNL287W SEC21 0.61 1.1 non-clathrin coat protein involved in transport between ER and Golgi
YMR158W 0.61 1.0
YDR343C HXT6 0.61 2.3 Repression of HXT6 expression by glucose requires SNF3
YKL129C MYO3 0.61 1.7 C myosin I
YOR312C RPL20B 0.61 1.8 Homology to rat L18a
YMR222C FSH2 0.61 1.6
YNL286W CUS2 0.61 0.8 cold sensitive U2 snRNA Supressor
YHR063C PAN5 0.61 1.6 ketopantoate reductase
YMR245W 0.61 1.0
YIL122W POG1 0.61 3.8 S Promoter of Growth; weak similarity to human transcription adaptor protein p300
YNL081C 0.61 1.1
YKL174C 0.61 1.3
YGL151W NUT1 0.61 1.5 Negative regulator of URS2 of the HO promoter
YAL013W DEP1 0.61 1.1 Regulator of phospholipid metabolism
YGL065C ALG2 0.61 2.5 glycosyltransferase
YDR038C ENA5 0.61 1.6 Na(+) ATPase
YMR058W FET3 0.61 6.4 S FET3 encodes a ferro-O2-oxidoreductase that is part of the high-affinity iron transport system
YER154W OXA1 0.61 1.7 Mediates the export of proteins from the mitchondrial matrix to the intermembrane space.
YLR406C RPL31B 0.61 2.0 Homology to rat L31
YNR037C RSM19 0.61 1.3 mitochondrial ribosome small subunit component
YGR197C SNG1 0.61 1.2 Involved in nitrosoguanidine resistance
YER130C 0.61 2.0
YDR147W EKI1 0.61 1.8 Ethanolamine Kinase 1
YBR123C TFC1 0.61 2.1 transcription factor tau (TFIIIC) subunit 95
YMR296C LCB1 0.61 2.2 "Serine palmitoyltransferase catalyses the committed step in sphingolipid synthesis, the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine."
YNL095C 0.61 1.8
YPL112C PEX25 0.61 1.1 required for regulation of peroxisome size and maintenance
YPL184C 0.61 1.4
YDR395W SXM1 0.61 0.9 Suppressor of mRNA export mutant; Importin-beta like gene
YGL227W VID30 0.61 1.3 vacuole import and degradation (VID); TOR inhibitor (TIN)
YGR284C ERV29 0.61 2.6 S ER Vesicle protein of 29 kDa (apparent MW)
YDR165W TRM82 0.61 1.0 Transfer RNA methyltransferase
YER166W DNF1 0.60 1.1 Drs2 Neo1 Family
YML006C GIS4 0.60 1.5 GIG3 suppressor
YML065W ORC1 0.60 2.6 S binds to origins of replication and thereby directs DNA replication and is also involved in transcriptional silencing
YMR204C 0.60 2.0
YGL234W "ADE5,7" 0.60 1.6 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase
YIL153W RRD1 0.60 2.1 Resistant to Rapamycin Deletion
YDR189W SLY1 0.60 1.3 Hydrophilic suppressor of ypt1 involved in vesicle trafficking between ER and Golgi
Sm like protein
YPL036W PMA2 0.60 4.6 S plasma membrane ATPase
YMR074C 0.60 1.0
YMR216C SKY1 0.60 1.9 SRPK1-like Kinase in Yeast (SRPK1 is a human serine kinase that specifically phosphoryates arginine-serine rich domains found in the SR family of splicing factors.)
YBR195C MSI1 0.60 1.0 "chromatin assembly complex, subunit 3: Encodes the smallest (p50) subunit of the yeast Chromatin Assembly Factor-I (CAF-I) involved in DNA-replication-linked nucleosome assembly. Homologous to the small subunit of the Human CAF-I."
YBR273C 0.60 2.6 S
YDR031W 0.60 1.4
YJL085W EXO70 0.60 1.7 70 kDa exocyst component protein; the exocyst proteins are required for exocytosis late in the secretory pathway
YML009C MRPL39 0.60 1.5 Mitochondrial ribosomal protein MRPL39 (YmL39)
YLR038C COX12 0.60 1.5 essential during assembly for full cytochrome c oxidase activity
YIL089W 0.60 1.1
YML099C ARG81 0.60 1.1 Regulator of arginine-responsive genes with ARG80 and ARG82
YKR069W MET1 0.60 2.4 S Methionine metabolism
YER188W 0.60 1.8
YNL108C 0.60 1.2
YBR147W 0.60 1.9
YKL133C 0.60 0.9
YKL077W 0.60 0.9
YNL190W 0.60 1.4
YIL036W CST6 0.60 0.9 Chromosome STability; contains an ATF/CREB-like bZIP domain; transcriptional activator; interacts with the STB locus on 2-micron plasmid
YIR023W DAL81 0.60 1.6 Positive regulator of multiple nitrogen catabolic genes
YDR456W NHX1 0.60 1.5 Required for intracellular sequestration of Na+
YER149C PEA2 0.60 2.6 S Pea2p is localized with Spa2p to sites of polarized growth and is required for efficient mating and bipolar budding; it is required for pheromone-induced shmoo formation
YGL063W PUS2 0.60 1.3 pseudouridine synthase 2
YCL008C STP22 0.60 0.8 Ste pseudorevertant; required for vacuolar targeting of temperature-sensitive plasma membrane proteins; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype.
YDR538W PAD1 0.60 0.8 Phenylacrylic acid decarboxylase
YGR054W 0.60 1.1
YEL077C 0.60 4.7 S
YKR017C 0.60 1.6
YOL115W TRF4 0.60 1.5 TRF5 homolog; Involved in mitotic chromsome condensation; associates with Smc1p and Smc2p
YLR435W 0.60 1.1
YHR071W PCL5 0.60 2.1 PHO85 cyclin
YAL058W CNE1 0.60 1.2 Functions in endoplasmic reticulum protein quality control
YLR055C SPT8 0.60 1.8 "transcription factor, probable member of histone acetyltransferase SAGA complex"
YKL038W RGT1 0.60 1.0 transcriptional repressor and activator
YGR095C RRP46 0.60 0.8 Ribosomal RNA Processing
YHR036W 0.60 1.2
YOR174W MED4 0.60 1.2 Member of RNA Polymerase II transcriptional regulation mediator
YJL129C TRK1 0.60 1.4 180 kDa high affinity potassium transporter
YDR039C ENA2 0.60 0.9 plasma membrane protein; putative Na+ pump; P-type ATPase
YNL202W SPS19 0.60 1.7 late sporulation specific gene which may function during spore wall formation
YJL225C 0.60 4.3 S
YPL151C PRP46 0.60 1.8 "protein required for pre-mRNA splicing in vivo, WD-protein homologous to Arabidopsis thaliana pleiotropic regulators PRL1 and PRL2"
YKL225W 0.60 1.3
YGL068W 0.60 1.5
YML086C ALO1 0.60 1.0 "D-arabinono-1,4-lactone oxidase"
YDR172W SUP35 0.60 0.9 altered form creates [PSI] prion
YLR342W FKS1 0.60 3.4 K S Required for viability of calcineurin mutants
YFL001W DEG1 0.60 1.2 Similar to rRNA methyltransferase (Caenorhabditis elegans) and hypothetical 28K protein (alkaline endoglucanase gene 5' region) from Bacillus sp.
YPR086W SUA7 0.60 1.0 transcription factor TFIIB homolog
YAL016W TPD3 0.60 1.1 protein phosphatase 2A regulatory subunit A
YKL092C BUD2 0.60 2.0 C GTPase-activating protein (GAP) for Rsr1p/Bud1p
YGL105W ARC1 0.60 1.2 associated with tRNA and amino acyl-tRNA synthetases; has affinity for quadruplex nucleic acids
YLR181C VTA1 0.60 1.1 Hypothetical ORF
YBL014C RRN6 0.60 1.3 involved in the transcription of 35S rRNA genes by RNA polymerase I
YPL225W 0.60 1.0
YOR381W FRE3 0.60 1.9 similar to FRE2
YBR271W 0.60 1.1
YDR056C 0.60 1.9
YBR239C 0.60 1.0
YER110C KAP123 0.60 2.2 "Karyopherin of predicted MW 122.524 Da. Similar to Kap95p (YLR347C) and Kap104p *YBR017C). Ran binding protein, Homolog of importin-beta"
YJR031C GEA1 0.60 3.1 Z component of a complex guanine nucleotide exchange activity for the ADP-ribosylation factor ARF
YIR010W DSN1 0.60 3.6 Z S Dosage Suppressor of NNF1
YDL148C NOP14 0.60 1.5 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); NucleOlar Protein 14
YKL205W LOS1 0.60 0.8 Nuclear pore protein involved in pre-tRNA splicing
YOL084W PHM7 0.60 1.4
YBL005W PDR3 0.60 1.0 Zinc-finger transcription factor related to Pdr1p
YGR150C 0.60 1.4
YER106W MAM1 0.60 1.6 Monopolar microtubule Attachment during Meiosis I
YOR330C MIP1 0.60 1.9 catalytic subunit of mitochondrial DNA polymerase
YDL098C SNU23 0.60 1.2 23 kD U4/U6.U5 snRNP associated protein
YDR215C 0.60 2.5
YBR039W ATP3 0.59 1.4 participates in catalysis of ATP hydrolysis/synthesis and in the assembly/stability of F1
YBR083W TEC1 0.59 4.4 K S C "transcription factor of the TEA/ATTS DNA-binding domain family, regulator of Ty1 expression"
YNL275W 0.59 0.9
YBR058C UBP14 0.59 1.2 Functional homolog of mammalian isopeptidase T; may facilitate proteolysis by preventing unanchored ubiquitin chains from competitively inhibiting polyubiquitin-substrate binding to the 26S proteasome
YKL039W PTM1 0.59 1.3 Putative membrane protein
YAL043C PTA1 0.59 1.1 pre-tRNA processing
YDR536W STL1 0.59 1.0 sugar transporter-like protein
YCL046W 0.59 1.2
YKL034W TUL1 0.59 1.2 Transmembrane Ubiquitin Ligase
YEL028W 0.59 1.9
YLR254C 0.59 3.3 S C
YDL060W TSR1 0.59 0.9
YDL199C 0.59 0.9
YHR124W NDT80 0.59 1.6 Meiosis-specific gene; mRNA is sporulation specific; required for exit from pachytene and for full meiotic recombination
YDR510W SMT3 0.59 1.5 may be involved in function and/or structure of the eukaryotic kinetochore
homologous to SUMO-1
YMR101C SRT1 0.59 2.4 cis-prenyltransferase involved in dolichol synthesis
YGL082W 0.59 1.5
YLR226W BUR2 0.59 1.6 bypass UAS Requirement
YJL101C GSH1 0.59 1.2 encodes the first enzyme involved in glutathione biosynthesis
YEL001C 0.59 1.1
YDL078C MDH3 0.59 1.4 malate dehydrogenase
YOL063C MOR1 0.59 1.2 MMS1 Related
YGR081C 0.59 0.8
YDR150W NUM1 0.59 3.1 K S C "May function in nuclear migration during mitosis and meiosis by affecting astral microtubule functions, perhaps by being involved in polymerization and stabilization of microtubules"
YNL194C 0.59 1.0
YCR015C 0.59 1.6
YBR279W PAF1 0.59 2.6 "RNA polymerase II-associated, nuclear protein that may serve as both a positive and negative regulator of a subset of genes, perhaps operating in parallel with Gal11p"
YMR293C 0.59 1.7
YHR190W ERG9 0.59 1.0 squalene synthetase
YHL016C DUR3 0.59 0.8 Urea active transport protein
YCR099C 0.59 2.8
YLR182W SWI6 0.59 2.0 Involved in cell cycle dependent gene expression
YCL050C APA1 0.59 1.2 "diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase I"
YJL106W IME2 0.59 1.3 "Positive regulator of meiosis, dispensable for mitosis, stimulates early, middle and late gene expression and negatively regulates IME1"
YGR110W 0.59 1.5
YDR028C REG1 0.59 1.2 The reg1 locus encodes a gene which is involved in RNA processing and is a negative regulator of glucose-repressible genes.
YJL019W MPS3 0.59 3.7 Z S MonoPolar Spindle
YMR196W 0.59 1.9
YBR237W PRP5 0.59 2.2 RNA helicase homolog
YAL021C CCR4 0.59 0.9 carbon catabolite repression; transcriptional regulator for some glucose-repressed genes including ADH2
YAL011W SWC1 0.59 1.3 Hypothetical ORF
YDR325W YCG1 0.59 1.8 C Yeast Condensin G
YPL167C REV3 0.59 1.1 "DNA polymerase zeta, which is unique in its ability to bypass thymine dimers during replication, is composed of Rev3p and Rev7p."
YLR335W NUP2 0.59 1.6 Localizes to discrete spots in the nuclear envelope; probably functions in transport through nuclear pore
YLR396C VPS33 0.59 1.0 vacuolar sorting protein essential for vacuolar morphogenesis and function
YMR197C VTI1 0.59 1.2 Involved in cis-Golgi membrane traffic
YMR198W CIK1 0.59 4.8 K Z S C chromosome instability and karyogamy; CIK1 is important for proper organiziation of microtubule arrays and establishment of a spindle; is essential for karyogamy; and expression is regulated by KAR4 and mating
YAR018C KIN3 0.59 5.9 K S C protein kinase
YAL048C 0.59 1.4
YLR448W RPL6B 0.59 1.1 Homology to rat and human L6; involved initiation of protein synthesis
YDR152W 0.59 1.1
YDR316W 0.59 1.8
YJR073C OPI3 0.59 1.7 Second and third steps of methylation pathway for phosphatidylcholine biosynthesis
YNL166C BNI5 0.59 2.5 S bud neck involved; localizes to mother-bud neck in a septin-dependent manner; bni5 shows synthetic enhancement of septin Ts- mutant phenotypes.
YLL036C PRP19 0.59 1.3 "Required for error prone repair, induced mitotic recombination, and sporulation"
YMR273C ZDS1 0.59 1.4 Negative regulator of cell polarity
YDR091C RLI1 0.59 1.6 Strong protein homology (68% identical) to human RNase L Inhibitor (RLI). Required for vegetative growth and early sporulation.
YJR162C 0.59 1.9
YBR008C FLR1 0.59 2.6 S Fluconazole Resistance 1
YLR419W 0.59 0.9
YJL045W 0.59 2.4
YDR208W MSS4 0.59 1.6 Involved in actin cytoskeleton organization; multicopy suppressor of stt4 mutation
YOR084W 0.59 3.7 Z S
YMR276W DSK2 0.59 1.4 Required with RAD23 for duplication of the spindle pole body
YHL042W 0.59 1.3
YDR469W SDC1 0.59 1.1 likely involved in chromatin remodeling
member of Set1p complex
YNL101W 0.59 1.7
YLR099C ICT1 0.59 2.4 S Increased Copper Tolerance; Similar to Ecm18p
YPR010C RPA135 0.59 1.1 135 kDa subunit of RNA polymerase I
YNL011C 0.59 0.8
YBR272C HSM3 0.59 1.0 Involved in DNA mismatch repair pathways
YER140W 0.59 2.4
YPL154C PEP4 0.59 1.5 vacuolar proteinase A
YHR169W DBP8 0.59 1.4 "Dead-Box Protein 8, ATP-dependent helicase involved in rRNA processing"
YFL004W VTC2 0.59 0.8 Phosphate metabolism; transcription is regulated by PHO system
YLR132C 0.59 1.1
YHR107C CDC12 0.59 1.7 involved in proper bud growth
YOR238W 0.59 1.1
YDR362C TFC6 0.59 0.8 91 kDa tau91 subunit of transcription factor IIIC (TFIIIC)
YLR077W 0.59 1.2
YGL208W SIP2 0.59 1.3 "Member of a family of proteins, including Sip1p and Gal83p, that interact with Snf1p and Snf4p and are involved in the response to glucose starvation"
YDR270W CCC2 0.58 1.0 copper-transporting P-type ATPase with similarity to human Menkes and Wilsons genes
YMR286W MRPL33 0.58 2.2 essential for mitochondrial function
YDR123C INO2 0.58 1.4 Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis
YKL110C KTI12 0.58 1.2 Protein involved in resistance to K. lactis killer toxin; RNA polymerase II Elongator associated protein
YGR100W MDR1 0.58 1.4 Mac1-dependent regulator
YIL067C 0.58 1.3
YDL218W 0.58 2.1
YJR132W NMD5 0.58 3.0 Involved in nuclear import
YER164W CHD1 0.58 1.3 "Sole S. cerevesiae member of CHD gene family containing Chromodomain, Helicase domain, and DNA-binding domain"
YIR017C MET28 0.58 3.5 S C Transcriptional activator of sulfur amino acid metabolism
YOR212W STE4 0.58 1.1 beta subunit of G protein coupled to mating factor receptor
YLL028W TPO1 0.58 5.7 S Polyamine transport protein
YDL121C 0.58 1.0
YGL002W ERP6 0.58 1.4 Emp24p/Erv25p related protein 6
YFL042C 0.58 1.7
YDR017C KCS1 0.58 1.2 Converts inositol hexakisphosphate to diphosphoinositol polyphosphates. Contains two leucine heptad repeats. Essential for biogenesis of the yeast vacuole and the cell's responses to certain environmental stresses.
YNL145W MFA2 0.58 4.7 K S lipopeptide mating pheromone
YJR106W ECM27 0.58 1.4 ExtraCellular Mutant
YCL030C HIS4 0.58 3.0 histidinol dehydrogenase
YHR206W SKN7 0.58 1.2 Protein with similarity to DNA-binding region of heat shock transcription factors
YDL238C 0.58 1.5
YPR105C COG4 0.58 1.0 Conserved Oligomeric Golgi complex 4
Complexed with Cog8p
YDL015C TSC13 0.58 1.4 ER protein involved in very long chain fatty acid synthesis
YJL037W 0.58 1.6
YBL109W 0.58 2.3
YOR352W 0.58 1.4
YPR117W 0.58 1.0
YOL112W MSB4 0.58 2.3 S Multicopy Suppressor of Bud Emergence
YJL146W IDS2 0.58 0.9 IME2-Dependent Signalling
YKL023W 0.58 1.4
YGL008C PMA1 0.58 4.5 S Major regulator of cytoplasmic pH. Part of the P2 subgroup of cation-transporting ATPases; functions physiologically to pump protons out of the cell.
YKL124W SSH4 0.58 0.8 Suppressor of SHR3; confers leflunomide resistance when overexpressed
YER125W RSP5 0.58 1.0 involved in ubiquitin-mediated protein degradation
YNR061C 0.58 1.3
YOL117W RRI2 0.58 2.0 subunit of COP9 Signalosome-like protein complex that cleaves the ubiquitin-like protein Rub1 from Cdc53
YGL123W RPS2 0.58 1.1 Homology to rat S2 and E. coli S5
YDR330W 0.58 1.9
YJR045C SSC1 0.58 0.9 Nuclear-encoded mitochondrial protein; member of the heat shock protein 70 (HSP70) family; most similar to E. coli DnaK protein; acts as a chaperone for protein import across the inner membrane
YDR438W 0.58 0.9
YLR246W ERF2 0.58 1.1 Mutation has an Effect on Ras Function. Implicated in signaling pathway.
YOR114W 0.58 4.1 Z S
YMR284W YKU70 0.58 1.5 "Shows homology to 70-kDa subunit of mammalian Ku protein, the regulatory subunit of the DNA-dependent protein kinase"
YNR035C ARC35 0.58 1.0 Arp complex subunit
YDR085C AFR1 0.58 3.5 S coordinates regulation of alpha-factor receptor signalling and induction of morphogenesis during conjugation
YDL237W 0.58 1.3
YKR007W 0.58 0.9
YPL017C 0.58 2.1
YNL045W 0.58 1.5
YGR101W PCP1 0.58 1.5 putative mitochondrial rhomboid protease
YLR092W SUL2 0.58 1.8 Sulfate uptake
YML125C 0.58 3.1 S
YDR245W MNN10 0.58 1.4 Required for mannan synthesis and for polarized growth and bud emergence
YIL001W 0.58 1.4
YCR008W SAT4 0.58 1.2 Protein with similarity to Npr1p protein kinase
YDR279W 0.58 2.9 S
YFR037C RSC8 0.58 1.7 C "8th largest subunit of RSC. Rsc8p mediates multiple RSC complex interactions, undergoes dimerization via the C-term coiled-coil segment, associates with SWI2/SNF2 ATPase Sth1p, forms a complex with RSC6p."
YLR461W PAU4 0.58 1.5 member of the seripauperin protein/gene family (see Gene_class PAU)
YOR093C 0.58 1.4
YLL046C RNP1 0.58 1.4 C ribonucleoprotein 1
YGL045W 0.58 1.0
YKR051W 0.58 1.0
YBR018C GAL7 0.58 1.1 galactose-1-phosphate uridyl transferase
YLR090W XDJ1 0.58 1.6 "Homolog of E. coli DnaJ, closely related to Ydj1p"
YHR032W 0.58 1.4
YPR196W 0.58 1.1
YEL055C POL5 0.58 1.0 DNA polymerase V that has motifs typical of DNA polymerase family. Aphidicolin-sensitive; stimulated by yeast proliferating cell nuclear antigen (PCNA).
YPR048W TAH18 0.58 1.3 Product of gene unknown
YLR033W RSC58 0.58 1.2 Remodels the structure of chromatin complex 58KDa subunit
YPL217C BMS1 0.58 1.3 BMH1 sensitive
YGL150C INO80 0.58 1.9 Shows similarity to the Snf2p family of DNA-dependent ATPases
YHR102W KIC1 0.58 0.9 Kinase that interacts with Cdc31p; N-rich kinase 1
YBR120C CBP6 0.58 1.0 Translational activator of COB mRNA
YDR371W CTS2 0.58 1.0 chitinase
YMR016C SOK2 0.58 1.6 Protein that can when overexpressed suppress mutants of cAMP-dependent protein kinase
YDL222C 0.58 1.8
YFR036W CDC26 0.58 1.2 "component of anaphase-promoting complex; required for ubiquitination of Clb2p and Clb3p, is a nuclear protein, and is induced by heat shock"
YBR026C MRF1' 0.58 1.8 Involved in mitochondrial fatty acid biosynthesis
YPL053C KTR6 0.58 1.7 "Similar to KRE2, mannosylphosphate transferase which may recognize any oligosaccharides with at least one alpha-1,2-linked mannobiose unit. Required for the transfer of mannosylphosphate to cell wall mannans."
YNL291C MID1 0.58 0.8 N-glycosylated integral plasma membrane protein
YPL172C COX10 0.58 1.7 Required for an essential posttranslational stage in assembly of cytochrome oxidase
YKR106W 0.58 1.4
YIR008C PRI1 0.58 1.9 K p48 polypeptide of DNA primase
YGR217W CCH1 0.58 1.5 calcium channel
YLL065W 0.58 3.8
YCR071C IMG2 0.58 1.2 required for integrity of mitochondrial genome
YJL047C RTT101 0.58 0.9 Regulator of Ty1 Transposition
YDL116W NUP84 0.58 1.0 "component of nuclear pores; Part of complex with Nup120p, Nup85p, Sec13p, and a Sec13p homolog"
YBR122C MRPL36 0.58 0.8 Mitochondrial ribosomal protein MRPL36 (YmL36)
YGL183C MND1 0.57 1.9 needed for Meiotic Nuclear Divisions
YOR348C PUT4 0.57 1.4 proline-specific permease (also capable of transporting alanine and glycine)
YEL037C RAD23 0.57 1.1 ubiquitin-like protein
YDR481C PHO8 0.57 3.3 S repressible alkaline phosphatase
YLR014C PPR1 0.57 1.1 C Positive regulator of URA1 and URA3
YBR284W 0.57 1.2
YIL068C SEC6 0.57 1.2 cytoplasmic protein involved in fusion of post-Golgi vesicles with the plasma membrane. The Exocyst complex is required for exocytosis.
YER077C 0.57 1.7
YOR323C PRO2 0.57 2.7 S second enzyme in proline biosynthesis
YMR244W 0.57 2.7
YMR103C 0.57 1.5
YGL233W SEC15 0.57 0.9 Protein involved in vesicle traffic between Golgi and plasma membrane. The Exocyst complex is required for exocytosis.
YOR022C 0.57 1.1
YDR074W TPS2 0.57 2.2 Trehalose-6-phosphate phosphatase
YKR086W PRP16 0.57 2.5 putative ATP-binding protein
YDL007W RPT2 0.57 1.0 Probable 26S protease subunit and member of CDC48/PAS1/SEC18 family of ATPases
YKL220C FRE2 0.57 1.5 "Ferric reductase, similar to Fre1p"
YER184C 0.57 0.8
YPL021W ECM23 0.57 4.5 S ExtraCellular Mutant; similar to SRD1. Negative regulator of pseudohyphal growth.
YKL134C 1-Oct 0.57 1.7 mitochondrial protein import machinery component involved in the biogenesis of the oxidative phosphorylation system
YNL232W CSL4 0.57 1.2 "Represses the replication of double-stranded RNA viruses, protecting the host from the otherwise lethal effects of the virus"
YOR358W HAP5 0.57 1.4 Regulates respiratory functions; subunit of a heterotrimeric complex required for CCAAT binding
YCL048W 0.57 1.5
YPR093C 0.57 1.5
YNL216W RAP1 0.57 2.6 Z S "DNA-binding protein involved in either activation or repression of transcription, depending on binding site context. Also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure."
YOL102C TPT1 0.57 1.2 Gene encodes a protein implicated in the last step of tRNA splicing in yeast: transfer of the splice junction 2'-phosphate from ligated tRNA to NAD
YGR103W NOP7 0.57 1.3 Nucleolar protein present in purified ribosome assembly intermediates. Required for rRNA processing; required for essential steps leading to synthesis of 60S ribosomal subunits.
YDL019C OSH2 0.57 1.1 Oxysterol Binding Protein
YOL032W 0.57 1.4
YNR008W LRO1 0.57 1.0 Lecithin cholesterol acyl transferase (LCAT) Related Orf
YGL009C LEU1 0.57 1.6 LEU1 encodes the second enzyme in leucine biosynthesis.
YNL051W COG5 0.57 1.4 Conserved Oligomeric Golgi complex 5
Complexed with Cog8p
YGL186C 0.57 1.4
YLL026W HSP104 0.57 2.5 "involved in thermal and ethanol tolerance, inheritance of [PSI+], and reactivation of mRNA splicing after heat shock"
YOL006C TOP1 0.57 1.7 topoisomerase I
YNL041C COG6 0.57 1.0 Conserved Oligomeric Golgi complex 6
Complexed with Cog8p; interacts with Cog2p
YER103W SSA4 0.57 1.8 member of 70 kDa heat shock protein family
YPL049C DIG1 0.57 1.7 "Down-regulator of Invasive Growth, Regulator of Sterile Twelve, binds Fus3 and Ste12"
YPL165C SET6 0.57 1.3
YPL242C IQG1 0.57 4.1 S C "Homolog of the mammalian IQGAP1 and 2 genes; probable regulator of cellular morphogenesis, inducing actin-ring formation in association with cytokinesis"
YMR210W 0.57 1.1
YML133C 0.57 3.7 S
YEL023C 0.57 1.5
YPR199C ARR1 0.57 1.5 Similar to transcriptional regulatory elements YAP1 and cad1
YKL072W STB6 0.57 1.2 binds Sin3p in two-hybrid assay
YKL217W JEN1 0.57 1.0 "Repressed by glucose, induced by lactic acid; in high copy, weakly suppresses cpr3 null mutan phenotype on lactate medium at 37 degrees"
YHL003C LAG1 0.57 1.4 YKL008C
YGR199W PMT6 0.57 1.3 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway
YBL067C UBP13 0.57 1.3 similar to Ubp9p
YOL148C SPT20 0.57 0.9 Transcription factor
YLL033W 0.57 2.4 Z
YJL113W 0.57 1.7
YGR239C PEX21 0.57 1.3 Peroxin; Pex18p and Pex21p are partially functionally redundant.
YMR213W CEF1 0.57 1.9 homolog of S. pombe cdc5+
YDR259C YAP6 0.57 1.8 bZIP protein
YOR387C 0.57 1.0
YIR036C 0.57 2.1 S
YDR390C UBA2 0.57 1.2 Protein with homology to mammalian ubiquitin activating (E1) enzyme
YCL025C AGP1 0.57 3.4 S broad substrate range permease which transports asparagine and glutamine with intermediate specificity
YJR154W 0.57 3.1 S
YOR307C SLY41 0.57 4.8 S multicopy suppressor of ypt1 deletion
YMR079W SEC14 0.57 1.1 Required for vesicle budding from the Golgi
YNL330C RPD3 0.57 0.8 Transcription modifier; required for vegetative repression of early meiosis-specific as well as non-meiotic genes; required for mitotic intragenic and intergenic recombination and for sporulation
YBR287W 0.57 2.6 S
YKR003W OSH6 0.57 2.0 Oxysterol Binding Protein
YLR357W RSC2 0.57 1.1 "RSC2 is a member of RSC complex, which Remodels the Structure of Chromatin. Also essential for the 2-micron plasmid to overcome maternal inheritance bias."
YPR027C 0.57 1.5
YKL021C MAK11 0.57 0.9 essential for cell growth and replication of M dsRNA virus; contains four beta-transducin repeats
YOR290C SNF2 0.57 1.7 involved in the coordinate regulation of phospholipid synthesis
YOL092W 0.57 1.4
YLR395C COX8 0.57 1.6 C Cytochrome-c oxidase chain VIII
YJL200C 0.57 2.0
YML113W DAT1 0.57 1.5 "datin, an oligo(dA).oligo(dT)-binding protein"
YIR014W 0.57 1.1
YOR100C CRC1 0.56 1.2 carnitine carrier
YMR089C YTA12 0.56 1.1 Mitochondrial ATPase (similar to E. coli FtsH protein) that resides in the innner mitochondrial membrane
YNL185C MRPL19 0.56 1.1 mitochondrial ribosomal protein of the large subunit
YCR105W 0.56 1.3
YPR120C CLB5 0.56 5.3 K Z S C role in DNA replication during S phase; additional functional role in formation of mitotic spindles along with Clb3 and Clb4
YER058W PET117 0.56 0.9 Required for assembly of active cytochrome c oxidase
YOL013C HRD1 0.56 0.9 Ubiquitin-protein ligase for endoplasmic reticulum-associated degradation.
YBL008W HIR1 0.56 1.0 Involved in cell-cycle regulation of histone transcription
YDR499W LCD1 0.56 1.4 required for the DNA integrity checkpoint pathways; S. pombe Rad26 functional homolog (putative)
YLR083C EMP70 0.56 2.9 identified as a 24 kDa cleavage product in endosome-enriched membrane fractions
YGR274C TAF1 0.56 0.9 TAFII complex component required for activated transcription
YJR127C ZMS1 0.56 1.5 Product of gene unknown
YPL160W CDC60 0.56 1.0 cytosolic leucyl tRNA synthetase
YLR192C HCR1 0.56 0.9 High Copy suppressor of RPG1
YER031C YPT31 0.56 1.1 probably involved in intra-Golgi transport or in the formation of transport vesicles at the most distal Golgi compartment
YHR140W 0.56 2.5
YFL046W 0.56 0.8
YER055C HIS1 0.56 1.2 involved in the first step of histidine biosynthesis
YOR079C ATX2 0.56 1.7 Multi-copy suppressor of SOD-linked defects
YHL010C 0.56 1.4
YDR384C ATO3 0.56 1.4 Ammonium Transport Outwards; member of the TC 9.B.33 YaaH family of putative transporters
YPR137W RRP9 0.56 1.2 "part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); Rrp9p is an ortholog of the human U3-55k protein; the human cDNA partially complements a yeast rrp9 null mutant. (Pluk et al. (1998) Mol. Cell. Biol. 18, 488-498.)"
YHR157W REC104 0.56 1.3 "meiosis-specific recombination gene, dispensable for mitotic recombination and axial elements in meiosis, required for tripartite synaptonemal complexes, meiotic recombination and spore viability; classified as an early recombination gene"
YNR072W HXT17 0.56 1.5 Hexose transporter
YDR256C CTA1 0.56 1.7 catalase A
YGL094C PAN2 0.56 2.4 Required for Pab1p-stimulated poly(A) ribonuclease activity
YNL187W 0.56 1.1
YDR188W CCT6 0.56 0.8 "cytoplasmic chaperonin of the Cct ring complex (previously called TCP1 or TRiC), distantly related to Tcp1p and to Hsp60"
YLR467W YRF1-5 0.56 4.8 S Y'-helicase protein 1
YDR545W YRF1-1 0.56 2.9 S Y'-helicase protein 1
YBR069C TAT1 0.56 2.4 S "Amino acid transport protein for valine, leucine, isoleucine, and tyrosine"
YLL012W 0.56 2.7 Z S
YMR093W UTP15 0.56 1.2 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YDR434W GPI17 0.56 1.3 Glycosyl Phosphatidyl Inositol 17
YDR444W 0.56 1.6
YMR316W DIA1 0.56 2.5 "may be involved in invasive growth, pseudohyphal growth"
YJL164C TPK1 0.56 1.9 putative catalytic subunit of cAMP-dependent protein kinase
YGR085C RPL11B 0.56 1.5 Homology to rat L11 and E. coli L5; involved in protein synthesis
YOR101W RAS1 0.56 2.1 ras proto-oncogene homolog
YPR174C 0.56 5.1 Z S C
YPR009W SUT2 0.56 0.9 Involved in sterol uptake; homologous to SUT1
YDL206W 0.56 0.9
YPR102C RPL11A 0.56 1.7 Homology to rat L11 and E. coli L5
YHR105W 0.56 1.1
YPL195W APL5 0.56 1.0 "Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function"
YHR149C 0.56 3.2 Z S
YNL237W YTP1 0.56 1.2 Yeast putative Transmembrane Protein
YAL026C DRS2 0.56 1.2 "P-type ATPase, potential aminophospholipid translocase"
YOR321W PMT3 0.56 2.8 S Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway
YBL105C PKC1 0.56 1.5 Protein Kinase C
YEL059C-A SOM1 0.56 1.8 "high copy suppressor of imp1 mutation, may be required for the function of the Imp1 peptidase and/or the protein sorting machinery"
YER170W ADK2 0.56 3.7 S Adenylate kinase (mitochondrial GTP:AMP phosphotransferase)
YJL070C 0.56 1.8
YDR505C PSP1 0.56 1.4 high-copy suppressor of cdc17 DNA polymerase alpha mutations
YBR015C MNN2 0.56 2.5 "Probable type II membrane protein involved in mannan synthesis. Catalyzes addition of first mannose to branches on poly l,6-mannose backbone of outer chain of cell wall N-linked mannans."
YLR222C UTP13 0.56 1.1 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YLR166C SEC10 0.56 1.3 "100 kD component of the Exocyst complex; required for exocytosis. The Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70."
YPR187W RPO26 0.56 0.9 "subunit common to RNA polymerases I, II, and III"
YOR229W WTM2 0.56 5.1 Z S C WD repeat containing transcriptional modulator 2
YKL008C LAC1 0.56 5.1 S Longevity-assurance gene 1 cognate (LAG1 cognate)
YNL143C 0.56 1.3
YLR300W EXG1 0.56 4.3 S "Has a broad specificity for beta-1,3-linkages as well as beta-1,6-linkages, and also for other beta-glucosidic linked substrates, such as cellobiose."
YMR128W ECM16 0.56 1.2 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); ExtraCellular Mutant
DEAH-box protein involved in ribosome synthesis
YBR043C AQR2 0.56 2.0 Z C "A(acid, azole) Q(quinidine) Resistance"
YJL124C LSM1 0.56 1.3 "Like Sm protein; the finding that Lsm1 contains the Sm consensus motifs and most closely resembles Sm-B has been controversial (Fromont-Racine et al, 1997 Nature Genetics 16:277-282, and Bertrand Seraphin, personal communication)."
YDL177C 0.56 2.1
YOR011W AUS1 0.56 1.0 ABC(ATP-binding cassette) protein involved in Uptake of Sterols
YIL065C FIS1 0.56 1.8 Involved in mitochondrial division
YML018C 0.56 1.2
YPR067W ISA2 0.56 1.7 Iron Sulfur Assembly -- IscA/NifA homolog
YGL164C 0.56 1.7
YJL171C 0.56 1.4
YMR049C ERB1 0.56 1.6 Eukaryotic Ribosome Biogenesis
YDL017W CDC7 0.56 1.4 "Required for mitotic DNA synthesis but dispensable for premeiotic DNA synthesis and spindle pole body duplication; required for synaptonemal complexes, meiotic recombination, spindle pole body separation and spindles"
YFR013W IOC3 0.56 1.0 Iswi One Complex
YLR382C NAM2 0.56 2.7 C mitochondrial leucyl tRNA synthetase
YHR098C SFB3 0.56 2.3 S binds to Sed5p and Sec23p by distinct domains
Lethal with sec-thirteen
YCL018W LEU2 0.56 1.7 leucine biosynthesis
YBR294W SUL1 0.56 1.5 Putative sulfate permease
YDR476C 0.56 1.1
YJR042W NUP85 0.56 1.3 Protein in nuclear pore complex; may function in nuclear envelope integrity; may also be involved in tRNA biogenesis
YCR044C PER1 0.56 0.9 Protein Processing in the ER
YML095C RAD10 0.56 1.0 endonuclease (with Rad1p) that degrades single-stranded DNA for repair
YNL279W PRM1 0.56 2.6 pheromone-regulated membrane protein
YBR223C TDP1 0.56 1.9 Tyrosine-DNA Phosphodiesterase
YOL018C TLG2 0.56 0.9 member of the syntaxin family of t-SNAREs
YOR316C COT1 0.56 1.2 C Protein involved in cobalt accumulation; dosage dependent suppressor of cobalt toxicity
YHR014W SPO13 0.56 1.4 Spo13 acts as a transcriptional activator in a one-hybrid assay (see Henninger et al (1996) SPO13 and control of meiotic chromosome segregation in Saccharomyces cerevisiae)
YDR062W LCB2 0.56 1.4 "Serine palmitoyltransferase catalyses the committed step in sphingolipid synthesis, the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine."
YHR007C ERG11 0.56 1.7 cytochrome P450 lanosterol 14a-demethylase
YMR238W DFG5 0.56 2.7 S "Protein required for filamentous growth, cell polarity, and cellular elongation"
YPL235W RVB2 0.56 0.8 "RUVB-like protein, TIP49b Homologue"
YML030W 0.56 1.7
YHR138C 0.56 1.9
YGR030C POP6 0.56 1.0 Processing Of Precursors - a group of proteins that appear to be components of both RNase P and RNase MRP
YNR052C POP2 0.56 0.9 Putative transcription factor
YJR086W STE18 0.56 1.5 gamma subunit of G protein coupled to mating factor receptors
YJL008C CCT8 0.55 0.8 Required for assembly of microtubules and actin in vivo
YJL153C INO1 0.55 3.8 involved in the rate limiting step of inositol biosynthesis
YDL241W 0.55 1.8
YKL121W 0.55 1.2
YLR330W CHS5 0.55 1.1 "Involved in chitin synthase III activity, also required for homozygosis in the first stages of mating"
YJR051W OSM1 0.55 1.2 osmotic growth protein
YDR221W 0.55 1.6
YLR053C 0.55 1.2
YMR026C PEX12 0.55 0.8 C3HC4 zinc-binding integral peroxisomal membrane protein
YAL027W 0.55 0.9
YML132W COS3 0.55 1.7 "Protein with strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p (COS3 and YBR302C code for identical proteins)"
YOR103C OST2 0.55 1.7 Oligosaccharyltransferase catalyzes the transfer of oligosaccharide from dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synthesized proteins in ER lumen
YBR302C COS2 0.55 1.2 "Protein with similarity to members of the Cos3/Cos5/Cos1/Cos4/Cos8/Cos6/Cos9 family, coded from subtelomeric region"
YMR122C 0.55 1.8
YML043C RRN11 0.55 1.8 "rDNA transcription factor CF component, which also contains Rrn6p and Rrn7p, which is required for rDNA transcription by RNA polymerase I"
YCR024C 0.55 1.2
YGR288W MAL13 0.55 1.8 "Part of complex locus MAL1; nonfunctional in S288C, shows homology to both functional & nonfunctional MAL-activator proteins in other Sc strains & to other nonfunctional MAL-activator sequences from S288C (i.e. MAL33, YPR196W, & YFL052W)"
YHR144C DCD1 0.55 0.9 dCMP deaminase
YHL002W HSE1 0.55 0.8 Has Symptoms of class E vps mutant
YBR084C-A RPL19A 0.55 1.4 Homology to rat L19
YBL027W RPL19B 0.55 1.5 Homology to rat L19
YDL040C NAT1 0.55 0.8 "Required for entry into stationary phase, heat shock-resistance, a mating-type functions, and sporulation; forms a complex with Ard1p"
YHR176W FMO 0.55 0.9 "catalyzes the O2- and NADPH-dependent oxidations of biological thiols, including oxidation of glutathione to glutathione disulfide"
YHR137W ARO9 0.55 2.7 S aromatic amino acid aminotransferase II
YML116W ATR1 0.55 2.5 S aminotriazole resistance
YLR221C RSA3 0.55 1.3 RiboSome Assembly
YDR443C SSN2 0.55 1.1 Required for stable association of Srb10p-Srb11p kinase with RNA polymerase holoenzyme; regulates YGP1 epxression; component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex
YLR164W 0.55 2.5
YDR478W SNM1 0.55 1.1 Has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing.
YKR018C 0.55 1.1
YHR119W SET1 0.55 1.2 Gene has a 'SET' or 'TROMO' domain at its carboxyterminus like the trithorax gene family from human and Drosophila with postulated function in chromatin-mediated gene regulation.
YKR072C SIS2 0.55 0.9 Involved in cell cycle control and ion homeostasis
YOL033W MSE1 0.55 1.6 Mitochondrial glutamyl-tRNA synthetase
YOR168W GLN4 0.55 1.5 glutaminyl-tRNA synthetase
YMR277W FCP1 0.55 2.1 TFIIF interacting Component of CTD Phosphatase
YBR278W DPB3 0.55 1.2 K C C and C' subunits of DNA polymerase II
YMR208W ERG12 0.55 1.5 mevalonate catabolism
YML088W UFO1 0.55 1.1 F-box protein
YER033C ZRG8 0.55 1.3 Zinc regulated gene
YOR256C 0.55 4.1 S
YDR244W PEX5 0.55 0.8 Essential for import of proteins with SKL-like import signal into peroxisomal matrix
YOR043W WHI2 0.55 1.2 "Protein involved in growth regulation. Whi2 and its binding partner, Psr1-phosphatase, are required for a full activation of the general stress response, possibly through the dephosphorylation of Msn2."
YGL095C VPS45 0.55 1.3 Protein of the Sec1p family essential for vacuolar protein sorting
YBL033C RIB1 0.55 1.3 First step in the riboflavin biosynthesis pathway
YNL152W 0.55 1.8
YOR301W RAX1 0.55 1.8 A rax1 mutation converts the budding pattern of an axl1 null mutant from bipolar to axial.
YIL107C PFK26 0.55 0.8 6-Phosphofructose-2-kinase
YJR061W 0.55 1.0
YHR155W 0.55 0.9
YLL067C 0.55 3.6 Z S
YNL059C ARP5 0.55 1.0 Actin-related protein. Part of the carboxypeptidase Y pathway.
YBR187W 0.55 2.1
YGL139W 0.55 2.9 Z
YPR148C 0.55 1.9
YNL121C TOM70 0.55 1.0 Translocase of Outer Mitochondrial membrane
YFL041W FET5 0.55 1.9 ferrous iron transport
YBR198C TAF5 0.55 1.0 TAF(II) complex (TBP-associated protein complex) component required for activated transcription by RNA polymerase II
YBR030W 0.55 1.1
YER160C 0.55 1.5
YML057W CMP2 0.55 1.4 calmodulin binding protein homologous to mammalian calcineurin
YBL103C RTG3 0.55 1.7 bHLH/Zip transcription factor which regulates CIT2 gene expression
YER162C RAD4 0.55 0.9 Nucleotide excision repair protein
YML029W USA1 0.55 1.8 "Identified by its interaction with the U1 snRNP-specific protein, Snp1p."
YDR375C BCS1 0.55 1.5 "Mitochondrial protein of the CDC48/PAS1/SEC18 ATPase family, required for expression of functional Rieske iron-sulfur protein"
YDR294C DPL1 0.55 1.4 dihydrosphingosine phosphate lyase (also known as sphingosine phosphate lyase)
YML023C 0.55 1.5
YMR028W TAP42 0.55 1.1 "Two A phosphatase Associated Protein, apparant MW of 42 kDA"
YDR030C RAD28 0.55 2.1 "Protein involved in the same pathway as Rad26p, has beta-transducin (WD-40) repeats"
YHL012W 0.55 1.0
YOR342C 0.55 2.7 S
YOR254C SEC63 0.55 1.5 Protein involved in protein import into ER
YIR034C LYS1 0.55 2.4 saccharopine dehydrogenase
YDR307W 0.55 2.3 S
YIL014W MNT3 0.55 1.3 MaNnosylTransferase; involved in adding the 4th and 5th mannose residues of O-linked glycans
YDR063W 0.55 0.9
YER151C UBP3 0.55 1.7 Possible role for UBP3 in controlling the activity or assembly of the SIR protein complex.
YGL153W PEX14 0.55 0.9 Peroxisomal peripheral membrane protein (peroxin) involved in import of peroxisomal matrix proteins
YML118W NGL3 0.55 1.7 DNase/RNase (putative); CCR4 C-terminal homolog; displays homology to drosophila Angel gene; homolog to ngl1 and ngl2
YFR010W UBP6 0.55 1.1 deubiquitinating enzyme (putative)
YBR216C 0.55 0.9
YLR386W VAC14 0.55 2.1 VACuole morphology and inheritance mutant
YJL111W CCT7 0.55 0.8 Required for assembly of microtubules and actin in vivo
YOL048C 0.55 1.2
YLR057W 0.55 3.0 S
YDL180W 0.55 2.1 S
YOR303W CPA1 0.55 1.3 "Carbamoyl phosphate synthetase, arginine specific"
YOR292C 0.55 1.5
YML062C MFT1 0.55 0.8 Protein involved in mitochondrial import of fusion proteins
YBL101W-B 0.55 1.1
YMR071C 0.55 2.7
YDL128W VCX1 0.55 1.7 S "Similar to sodium/calcium exchangers, including bovine Na+/Ca2+,K+ antiporter; putative vacuolar transmembrane protein"
YMR061W RNA14 0.55 0.9 Protein with a role in mRNA stability and/or poly(A) tail length
YNL293W MSB3 0.55 2.2 Multicopy Suppressor of Bud Emergence
YJL012C VTC4 0.55 1.1 Phosphate metabolism; transcription is regulated by PHO system
YBL006C 0.55 1.1
YFR011C 0.55 1.2
YGL210W YPT32 0.55 1.2 probably involved in intra-Golgi transport or in the formation of transport vesicles at the most distal Golgi compartment
YOR302W 0.55 0.9
YLR210W CLB4 0.55 3.8 K Z S C Involved in mitotic induction
YBL043W ECM13 0.55 1.9 ExtraCellular Mutant
YML012W ERV25 0.55 2.6 S COPII coat component of certain ER-derived vesicles
YDR057W YOS9 0.55 1.1 Appears to play a direct role in the transport of GPI-anchored proteins to the Golgi apparatus.
YLR025W SNF7 0.55 1.3 Involved in derepression of SUC2 in response to glucose limitation
YML101C CUE4 0.55 1.7 Hypothetical ORF
YNR013C PHO91 0.55 1.7 Low-affinity phosphate transporter
YBR118W TEF2 0.55 2.4 translational elongation factor EF-1 alpha
YPR080W TEF1 0.55 1.8 translational elongation factor EF-1 alpha
YGL112C TAF6 0.55 1.1 TATA-binding protein-associated-factor
YDR397C NCB2 0.55 1.1 Negative Cofactor B2 is the beta subunit of a negative regulator of RNA polymerase II holoenzyme. It is homologous to the Dr1 subunit of the mammalian NC2 (negative cofactor2)
YGL155W CDC43 0.55 1.1 may participate in a ras-like C-terminus modification of proteins involved in nuclear division and bud growth
YDR449C UTP6 0.55 1.2 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YGR092W DBF2 0.55 5.3 K S C Kinase required for late nuclear division. Cdc15 promotes the exit from mitosis by directly switching on the kinase activity of Dbf2.
YDL164C CDC9 0.54 4.7 K Z S C "essential for mitosis and meiosis, dispensable for intragenic recombination, but required for haploidization and spores"
YNL138W SRV2 0.54 1.1 N-terminal domain appears to be involved in cellular responsiveness to RAS.
YDL099W 0.54 1.7
YAR031W PRM9 0.54 1.9 pheromone-regulated membrane protein
YAL005C SSA1 0.54 3.1 Stress-seventy subfamily A
YML121W GTR1 0.54 1.1 Involved in the function of the Pho84 phosphate transporter
YNL302C RPS19B 0.54 1.4 Homology to rat S19
YOR274W MOD5 0.54 2.1 C transfer RNA isopentenyl transferase
YDR171W HSP42 0.54 1.8 Similar to HSP26; expression is regulated by stress conditions
YLR369W SSQ1 0.54 1.2 Stress seventy Q. involved in the synthesis and assembly of iron/sulfur clusters into proteins.
YLR102C APC9 0.54 1.3 subunit of the Anaphase Promoting Complex
YER052C HOM3 0.54 1.3 First step in common pathway for methionine and threonine biosynthesis
YPR194C OPT2 0.54 1.3 oligopeptide transporter
YJR065C ARP3 0.54 1.2 actin-related gene
YLR288C MEC3 0.54 2.3 Z S Involved in checkpoint control and DNA repair
YER186C 0.54 1.1
YIL033C BCY1 0.54 1.8 "Involved in heat shock resistance, glycogen accumulation, and sporulation"
YKL042W SPC42 0.54 3.3 K Z S C "involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane"
YLR259C HSP60 0.54 1.2 60 kDa heat shock protein
YBL061C SKT5 0.54 2.2 S "protoplast regeneration and killer toxin resistance gene, may be a post-translational regulator of chitin synthase III activity, interacts with Chs3p"
YIR007W 0.54 1.2
YDR218C SPR28 0.54 2.1 Septin-related protein expressed during sporulation
YHR200W RPN10 0.54 1.4 "homolog of the mammalian S5a protein, component of 26S proteasome"
YNL026W 0.54 0.9
YGR048W UFD1 0.54 1.6 Ubiquitin fusion degradation protein
YJL186W MNN5 0.54 1.4 mannan synthesis
YGR257C 0.54 0.8
YKL002W DID4 0.54 1.4
YNL008C ASI3 0.54 1.1 "Amino acid Sensor-Independent (ASI) genes encode membrane proteins Asi1p, Asi2p and Asi3p. Asi1p and Asi3p have conserved ubiquitin ligase-like RING domains at their C-termini"
YNL062C GCD10 0.54 1.2 First identified as negative regulator of GCN4 expression
YHR207C SET5 0.54 1.3
YGL119W ABC1 0.54 1.7 Z "multicopy suppressor of a cytochrome b mRNA translation defect, essential for the electron transfer in the bc1 complex"
YLL009C COX17 0.54 1.5 Involved in copper metabolism and assembly of cytochrome oxidase
YGL185C 0.54 2.2 Z S
YKL096W-A CWP2 0.54 4.6 S "major constituent of the cell wall containing GPI-anchor, plays a role in stabilizing the cell wall, low pH resistance protein"
YHR214C-B 0.54 1.1
YKR087C 0.54 0.9
YHR048W 0.54 0.8
YML042W CAT2 0.54 2.2 "Carnitine O-acetyltransferase, peroxisomal and mitochondrial"
YER085C 0.54 1.8
YMR294W JNM1 0.54 1.5 coiled-coil domain protein required for proper nuclear migration during mitosis (but not during conjugation)
YOL131W 0.54 1.1
YEL031W SPF1 0.54 1.4 Sensitivity to a killer toxin (SMK toxin) produced by Pichia Farinosa
YPL145C KES1 0.54 2.1 Homologous to human oxysterol-binding protein; implicated in ergosterol biosynthesis and regulation of Golgi-derived transport vesicle biogenesis
YPL274W SAM3 0.54 2.7 S S-adenosylMethionine Permease
YMR100W MUB1 0.54 1.5 Homolog of samB gene of Aspergillus nidulans (deletion of samB results in mislocalization of septa
YDL210W UGA4 0.54 1.4 GABA-specific transport protein
YNR060W FRE4 0.54 1.7 similar to FRE2
YJR082C EAF6 0.54 3.3 Esa1p-Associated Factor-6
YER165W PAB1 0.54 0.9 "Poly(A) binding protein, cytoplasmic and nuclear"
YBR186W PCH2 0.54 1.4 Pachytene CHeckpoint
YBL024W NCL1 0.54 0.9 "Nuclear protein 1, similar to NOP2 and human proliferation associated nucleolar protein p120"
YIR006C PAN1 0.54 1.0 Involved in actin organization and endocytosis
YGR066C 0.54 1.5
YIL052C RPL34B 0.54 0.8 Homology to rat L34
YDR322W MRPL35 0.54 1.1 Mitochondrial ribosomal protein MRPL35 (YmL35)
YDR064W RPS13 0.54 1.7 Homology to rat S13
YBL097W BRN1 0.54 2.9 C "BaRreN, a gene with sequence similarity to Drosophila barren and Xenopus XCAP-H, and a functional homolog of human BRRN1"
YCR096C HMRA2 0.54 1.7 "Silenced copy of A2, which encodes a protein of unknown function."
YDR381W YRA1 0.54 1.3 Yeast RNA Annealing Protein
YOR194C TOA1 0.54 1.8 "Transcription factor IIA, large chain"
YNL087W 0.54 2.0
YGL055W OLE1 0.54 6.7 S C converts saturated fatty acyl-CoAs into cis-Delta-9 unsaturated fatty acids.
YJL068C 0.54 1.4
YLR097C 0.54 1.8
YJR029W 0.54 1.0
YNL034W 0.54 1.8
YEL041W 0.53 1.7
YDR026C 0.53 1.1
YIL048W NEO1 0.53 1.0 ATPase that leads to neomycin-resistant protein when overexpressed
YML020W 0.53 2.2 S
YIL021W RPB3 0.53 1.2 45 kDa subunit of RNA polymerase II
YNL311C 0.53 1.4
YGR177C ATF2 0.53 3.7 Z S Alcohol acetyltransferase
YJR083C 0.53 2.0
YDR222W 0.53 1.8
YPL210C SRP72 0.53 1.2 part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
YKL112W ABF1 0.53 2.6 transcriptional activator and ARS1 binding protein
YPL123C RNY1 0.53 2.1 RiboNuclease from Yeast
YER109C FLO8 0.53 1.3 "Nuclear protein required for diploid filamentous growth, haploid invasive growth and flocculation; note that S288C strains have a mutation in this gene"
YGR230W BNS1 0.53 3.9 S C bypasses need for SPO12
YLR085C ARP6 0.53 1.2 Actin-related protein. Part of the carboxypeptidase Y pathway.
YPL178W CBC2 0.53 1.1 cap binding complex
YLR115W CFT2 0.53 1.4 "cleaves pre-mRNAs prior to polyadenylation; homologous to both the 73- and 100-kDa subunits of mammalian cleavage and polyadenylation specificity factor (CPSF), as well as to YSH1/BRR5"
YLR324W 0.53 1.3
YGR033C 0.53 1.0
YDL122W UBP1 0.53 2.1 Ubiquitin-specific protease
YDR461W MFA1 0.53 3.4 S a-factor mating pheromone precursor
YNL305C 0.53 1.1
YHR022C 0.53 2.7 S C
YCR019W MAK32 0.53 1.5 Protein necessary for structural stability of L-A double-stranded RNA-containing particles
YDR361C BCP1 0.53 1.0 Hypothetical ORF
YNL018C 0.53 2.9
YNR069C 0.53 2.3
YER053C 0.53 2.5
YDR337W MRPS28 0.53 2.3 S Mitochondrial ribosomal protein MRPS28 (E. coli S15)
YPL245W 0.53 1.2
YBL005W-B 0.53 1.0
YJL062W LAS21 0.53 1.2 Local Anesthetics Sensitive: involved in the attachment of glycosylphosphatidylinositol (GPI) anchors to proteins.
YNL022C 0.53 0.9
YFR024C-A LSB3 0.53 2.5 LAs17 Binding protein
YGR067C 0.53 2.3
YJR041C 0.53 1.7
YPL087W YDC1 0.53 1.5 Yeast dihydro-ceramidase
YDR430C CYM1 0.53 1.0 CYtosolic Metalloprotease
YNL147W LSM7 0.53 1.9 Like Sm-G protein
YBR062C 0.53 1.1
YDR211W GCD6 0.53 1.0 "Guanine nucleotide exchange factor, 81 kDa subunit"
YGR167W CLC1 0.53 1.5 Clathrin light chain
YHR117W TOM71 0.53 0.9 "Translocase of the Outer Mitochondrial membrane, 71.9 kDa"
YPL096W PNG1 0.53 1.3 de-N-glycosylation enzyme
YLR188W MDL1 0.53 1.8 ATP-binding cassette (ABC) transporter family member
YMR105C PGM2 0.53 2.6 Phosphoglucomutase
YOL057W 0.53 1.4
YPL223C GRE1 0.53 2.2 Induced by osmotic stress
YDL075W RPL31A 0.53 1.3 Homology to rat L31
YBR285W 0.53 2.3
YIL023C 0.53 1.9
YML013W SEL1 0.53 1.0 SEcretion Lowering
YGR264C MES1 0.53 1.2 methionyl tRNA synthetase
YER065C ICL1 0.53 1.0 component of glyoxylate cycle
YJR076C CDC11 0.53 2.4 Z C involved in proper bud growth
YPL037C EGD1 0.53 1.1 beta subunit of the nascent-polypeptide-associated complex (NAC); homologous to human BTF3b; GAL4 enhancer protein
YKL063C 0.53 1.5
YAR014C BUD14 0.53 1.5
YAL034C FUN19 0.53 1.4 Function unknown now
YEL030W ECM10 0.53 1.6 ExtraCellular Mutant
YER027C GAL83 0.53 1.5 Glucose repression protein
YGL216W KIP3 0.53 3.6 Z S Kinesin-related protein
YFR035C 0.53 1.4
YDL030W PRP9 0.53 1.0 "involved in pre-spliceosome assembly, important for U2 snRNP addition"
YLL024C SSA2 0.53 1.9 member of 70 kDa heat shock protein family
YGL175C SAE2 0.53 2.7 Involved in meiotic recombination and chromosome metabolism
YOL051W GAL11 0.53 0.9 Regulates transcription of a diverse array of genes. Required for mating and sporulation.
YPR006C ICL2 0.53 1.4 2-methylisocitrate lyase
YER138C 0.53 1.7
YGR289C MAL11 0.53 2.2 "Part of MAL1 complex locus; encodes funct. maltose permease in all strains, exhibits sign. seq. variability; shows homol. to functional maltose permease from S. carlsbergenesis; member of the 12 tm domain superfamily of sugar transporters"
YEL053C MAK10 0.53 1.4 Glucose-repressible protein
YDR126W SWF1 0.53 1.4 Spore Wall Formation
YBR240C THI2 0.53 1.0 Transcriptional activator of thiamine biosynthetic genes
YLL004W ORC3 0.53 1.3 Third subunit of the origin recognition complex
YOR197W MCA1 0.53 1.4 metacaspase
YAR002C-A ERP1 0.53 0.8 Emp24p/Erv25p related protein
YBR139W 0.53 3.2 S
YLR291C GCD7 0.53 0.8 "translation initiation factor eIF2b, 43 kDa subunit; negative regulator of GCN4 expression"
YDR403W DIT1 0.53 0.8 "Disp. for spores & spore viability - required for dityrosine accumul. in the outer spore wall (s.w.), s.w. maturation & resist. to ether & lytic enzymes. Spore-autonomous function in heterozygotes. mRNA is trans. mid/late in s.w. formation"
YBL028C 0.53 1.3
YBR154C RPB5 0.53 1.1 "25-kDa RNA polymerase subunit (common to polymerases I, II and III)"
YLL007C 0.53 1.7
YJL155C FBP26 0.53 2.0 "fructose-2,6-bisphosphatase"
YLR088W GAA1 0.53 1.4 ER protein essential for attaching GPI (glycosylphosphatidylinositol) to protein
YHL043W ECM34 0.53 1.0 ExtraCellular Mutant
YLL066C 0.53 4.4 S
YKL188C PXA2 0.53 1.4 Homolog of the human adrenoleukodystrophy transporter; forms a heterodimer with Pxa1p of two half ATP-binding cassette transporters in the peroxisome membrane
YJL141C YAK1 0.53 1.0 Serine-threonine protein kinase
YCR054C CTR86 0.53 1.1 CTR86 shares a terminator region with THR4. CTR86 contains aGCN4 responsive site suggesting it may also be involved in amino acid biosynthesis.
YDL123W SNA4 0.53 1.0 Homology to PMP3/SNA1 (Sensitivity to Na+)
YML128C MSC1 0.53 2.6 Meiotic Sister-Chromatid recombination
YER179W DMC1 0.53 1.4 "Dispensable for double strand breaks, synaptonemal complexes, gene conversion in return to growth assay. Required for full pairing by in situ hybrid. assay, wt time of appearance of synaptonemal complexes and reciprocal Rec in growth assay"
YDR121W DPB4 0.53 1.0 "DNA Polymerase B (II), 4th subunit"
YJL044C GYP6 0.53 3.3 Z S GTPase-activating protein for Ypt6
YNL193W 0.53 0.8
YMR185W 0.53 1.0
YIL076W SEC28 0.52 1.8 S Part of a heptameric protein complex that regulates retrograde Golgi-to-ER protein traffic in eukaryotic cells; coatomer forms the COP I vesicle coat whose functions are essential
YBR296C PHO89 0.52 4.3 Z S Probable Na+/Pi symporter
YNL088W TOP2 0.52 1.5 "dispensable for premeiotic DNA synthesis and recombination, but required for meiosis I"
YLR308W CDA2 0.52 3.4 Required for proper formation of the ascospore wall
YPR111W DBF20 0.52 2.9 S C kinase required for late nuclear division
YLL039C UBI4 0.52 1.8 involved in stress response system
YIR026C YVH1 0.52 1.5 nitrogen starvation-induced protein phosphatase
YLR439W MRPL4 0.52 1.2 essential for mitochondrial function and for proper cell growth under non-respiratory conditions
YGR107W 0.52 1.3
YAL020C ATS1 0.52 1.6 Protein with similarity to human RCC1 protein
YPR063C 0.52 1.3
YBR036C CSG2 0.52 0.8 "Required for growth in high (>25mM) calcium, contains 9 or 10 putative membrane spanning regions"
YHL018W 0.52 2.1
YLR087C CSF1 0.52 0.9 "Cold Sensitive for Fermentation
in cs mutants, fermentation capacity is almost none at 5 deg C, but restored to wild type at 25 deg C"
YNR030W ECM39 0.52 1.8 mannosyltransferase
YDR170C SEC7 0.52 1.0 Involved in protein transport at multiple stages of the secretory pathway
YBR169C SSE2 0.52 1.4 "HSP70 family member, highly homologous to Sse1p"
YHL046C 0.52 1.3
YLR267W BOP2 0.52 1.4 bypass of PAM1
YMR126C 0.52 1.6
YNR045W PET494 0.52 1.1 translational activator of cytochrome c oxidase
YHL037C 0.52 2.0
YNL229C URE2 0.52 0.9 Nitrogen catabolite repression regulator that acts by inhibition of GLN3 in good nitrogen source. Altered form of Ure2p creates [URE3] prion.
YKL156W RPS27A 0.52 1.0 Homology to mammalian S27
YLR199C 0.52 1.3
YNL312W RFA2 0.52 4.2 K Z S C "Involved in nucleotide excision repair
RFA1, RFA2, and RFA3 make up RPA"
YJR027W 0.52 1.1
YBR017C KAP104 0.52 1.2 "Karyopherin of 103,613 Da. Similar to yeast karyopherin beta (Kap95p; YLR347c)"
YKL128C PMU1 0.52 1.8 "Phospho MUtase homolog. Small region homologous to active site of phospho-mutases, these move phosphates via a phospho-histidine intermediate. Homologs include: Sc GPM1, bact. Pgm, Hs Bpgm & rat fructose-2,6-bisphosphatase"
YJR155W AAD10 0.52 2.7 Z S C high degree of similarity with the AAD of P. chrysosporium
YLR262C YPT6 0.52 1.5 Ras-like GTP binding protein involved in the secretory pathway. Ypt6p is required for fusion of endosome-derived vesicles with the late Golgi.
YNL165W 0.52 2.7 S
YGR121C MEP1 0.52 1.8 belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH(4)(+) + NH(3)).
YDL072C 0.52 1.4
YBR131W CCZ1 0.52 0.9 Calcium Caffeine Zinc sensitivity
YML082W 0.52 1.1
YPL003W ULA1 0.52 1.7 Required for activation of RUB1 (ubiquitin-like protein) together with UBA3. Related to AOS1 and to N-terminus of UBA1. Collaborates with UBC12 in conjugation of RUB1 to other proteins. Required for modification of CDC53/cullin with RUB1
YIR025W MND2 0.52 0.9 needed for Meiotic Nuclear Division
YBR048W RPS11B 0.52 2.0 "Homology to rat S11, human S11, and E. coli S17"
YDR025W RPS11A 0.52 2.6 "Homology to rat S11, human S11, and E. coli S17"
YGR235C 0.52 1.1
YOR015W 0.52 1.2
YLR268W SEC22 0.52 1.4 Synaptobrevin (v-SNARE) homolog present on ER to Golgi vesicles
YNL100W 0.52 0.9
YLR440C 0.52 1.4
YGR191W HIP1 0.52 1.5 histidine permease
YML102W CAC2 0.52 4.3 Z S C Involved in DNA-replication-linked nucleosome assembly; homologous to the p60 subunit of the Human CAF-I
YHR076W PTC7 0.52 1.6
YMR123W PKR1 0.52 1.1 Pichia farinosa Killer toxin Resistance
YEL069C HXT13 0.52 1.5 high-affinity hexose transporter
YJL163C 0.52 1.3
YDR040C ENA1 0.52 2.0 Plasma membrane Na+ pump; P-type ATPase
YPL023C MET12 0.52 1.6 Gene encodes mthfr which catalyzes step before methionine synthesis.
YML045W 0.52 1.7
YCL007C CWH36 0.52 1.3 calcofluor white hypersensitivity
YOL121C RPS19A 0.52 0.9 Homology to rat S19
YKL182W FAS1 0.52 1.6 S "pentafunctional enzyme consisting of the following domains : acetyl transferase, enoyl reductase, dehydratase and malonyl/palmityl transferase"
YGR171C MSM1 0.52 1.3 mitochondrial methionyl-tRNA synthetase
YBR297W MAL33 0.52 1.7 "Part of complex locus MAL3; nonfunctional in S288C, shows homology to both functional & nonfunctional MAL-activator proteins in other Sc strains & to other nonfunctional MAL-activator sequences from S288C (i.e. MAL33, YPR196W, & YFL052W)"
YDR054C CDC34 0.52 1.5 "ubiquitin-conjugating enzyme, E2"
YGR183C QCR9 0.52 1.8 C 7.3 kDa subunit 9 of the ubiquinol cytochrome c oxidoreductase complex
YGL203C KEX1 0.52 1.2 Killer toxin and alpha factor precursor processing. Kex1p can cleave lys and arg residues from the C-terminus of peptides and proteins.
YIL085C KTR7 0.52 1.3 Putative mannosyltransferase of the KRE2 family
YLR167W RPS31 0.52 1.4 Homology to rat S27a
YPR062W FCY1 0.52 1.3 cytosine deaminase highly homologous to Candida albicans cytosine deaminase
YBL072C RPS8A 0.52 3.1 Homology to mammalian S8
YER102W RPS8B 0.52 1.5 Homology to mammalian S8
YPL214C THI6 0.52 1.2 thiamin biosynthetic bifunctional enzyme
YOR357C GRD19 0.52 0.8 Functions in Golgi retention.
YPL166W 0.52 1.3
YDR416W SYF1 0.52 1.0 SYnthetic lethal with cdcForty
YNL164C IBD2 0.52 0.8 Inhibition of Bud Division
YNL119W 0.52 1.3
YGL194C HOS2 0.52 1.5 "Protein with similarity to Hda1p, Rpd3p, Hos1p, and Hos3p"
YNL027W CRZ1 0.52 1.2 calcineurin responsive zinc-finger
YFR009W GCN20 0.52 0.8 Positive effector of the EIF-2-alpha kinase activity of GCN2; component of a heteromeric complex that includes GCN1 and GCN20
YCR090C 0.52 1.2
YLR423C APG17 0.52 1.2 required for activation of Apg1 protein kinase
YGR278W CWC22 0.52 1.3 Complexed with Cef1p
YOR046C DBP5 0.52 1.1 Dead-Box protein 5
YDR527W 0.52 1.6
YLR347C KAP95 0.52 1.4 S protein involved in nuclear import; required for the docking of import substrate to the nuclear membrane/pore; identified as an rna1-1 synthetic lethal
YBL016W FUS3 0.52 2.1 Required for the arrest of cells in G(sub)1 in response to pheromone and cell fusion during conjugation
YER016W BIM1 0.52 3.2 S C binding to microtubules
YOL128C YGK3 0.52 1.4 Yeast homologue of mammalian Glycogen Synthase 3
YOR276W CAF20 0.52 0.8 "binds to eIF-4E, the mRNA cap-binding protein, and represses cap-dependent translation initiation by interfering with the interaction of eIF4E and eIF4G"
YPR084W 0.52 1.0
YIL055C 0.52 2.3
YDR382W RPP2B 0.52 2.8 "Homology to rat P2, human P2, and E.coli L12eIA"
YKR082W NUP133 0.52 1.7 "Nuclear pore complex protein involved in poly(A)+ RNA transport, nuclear pore distribution, and possibly in the biogenesis of functional tRNA"
YOR124C UBP2 0.52 1.0 Ubiquitin-specific protease
YPL272C 0.52 0.8
YPR135W CTF4 0.52 4.5 Z S May function in DNA synthesis
YBR168W 0.52 1.1
YOR029W 0.51 2.5
YNL278W CAF120 0.51 1.4 CCR4 Associated Factor 120 kDa
YHR028C DAP2 0.51 1.1 Dipeptidyl aminopeptidase B (DPAP B)
YDR129C SAC6 0.51 0.8 fibrim homolog (actin-filament bundling protein)
YMR112C MED11 0.51 1.2 14 Kd mediator subunit of RNA polymerase II holoenzyme
YOR237W HES1 0.51 3.2 Protein implicated in ergosterol biosynthesis
YDL063C 0.51 1.8
YPL270W MDL2 0.51 1.4 ATP-binding cassette (ABC) transporter family member
YPR049C CVT9 0.51 1.4 "Oligomeric, coiled-coil, peripheral membrane protein"
YMR092C AIP1 0.51 2.0 Protein localizes to actin cortical patches. Probable binding site on actin lies on front surface of subdomain 3 and 4.
YDR014W RAD61 0.51 1.5 Affects radiation sensitivity
YGR201C 0.51 0.8
YDR043C NRG1 0.51 1.3 involved in regulation of glucose repression
YKR031C SPO14 0.51 1.2 "Catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid. Dispensable for mitosis, premeiotic DNA synthesis, recombination, meiosis I. Required for commitment to meiosis, meiosis II and sporulation."
YER025W GCD11 0.51 0.8 eIF2 is a heterotrimeric GTP-binding protein
SUI2 encodes the alpha subunit
SUI3 encodes the beta subunit
YPL181W RXT1 0.51 1.2 Hypothetical ORF
YBL010C 0.51 1.7
YJL020C BBC1 0.51 1.3 shows synthetic fitness defect with bni1 mutants and associates with the Bee1p-Vrp1p-Myo3/5p complex
YDR176W NGG1 0.51 1.5 Involved in glucose repression of GAL4p-regulated transcription
YDR542W 0.51 1.4
YML097C VPS9 0.51 0.8 "Required for Golgi to vacuole trafficking, shares similarity to mammalian ras inhibitors"
YKL052C ASK1 0.51 3.5 S C Associated with Spindles and Kinetochores
YDR068W DOS2 0.51 1.4 Product of gene unknown
YOR001W RRP6 0.51 1.9 Ribosomal RNA Processing
YMR077C VPS20 0.51 0.9 vaculolar protein sorting (putative)
YDL217C TIM22 0.51 1.2 Mitochondrial inner membrane protein involved in import of proteins of the ADP/ATP carrier (AAC) family
YIL097W FYV10 0.51 2.0 Function required for Yeast Viability on toxin exposure
YNR031C SSK2 0.51 1.4 Suppressor of Sensor Kinase (SLN1)
YNL180C RHO5 0.51 1.5 Rho family of small GTPases
YHR067W RMD12 0.51 1.8 S Required for Meiotic nuclear Division
YDR488C PAC11 0.51 3.0 S C Protein required in the absence of Cin8p
YEL047C 0.51 3.6 S
YHR132C ECM14 0.51 1.0 ExtraCellular Mutant
YDR166C SEC5 0.51 1.2 107 kDa component of the Exocyst complex; required for exocytosis.
YER030W 0.51 1.4
YPL240C HSP82 0.51 2.5 82 kDa heat shock protein; homolog of mammalian Hsp90
YOL025W LAG2 0.51 1.1 affects longevity
YNL329C PEX6 0.51 1.4 Required for peroxisome assembly
YGL060W 0.51 2.5 S
YBL034C STU1 0.51 1.6 Suppressor of cold-sensitive tub2 mutation; shown to be a component of the mitotic spindle
YHR146W CRP1 0.51 2.9 S Cruciform DNA Binding Protein 1
YDR036C 0.51 0.9
YER067W 0.51 1.5
YDR100W 0.51 0.8
YDR242W AMD2 0.51 1.4 putative amidase
YML019W OST6 0.51 1.7 Putative new 37kDa subunit of N-oligosaccharyltransferase complex
YNL036W NCE103 0.51 2.7 endogenous substrate for nonclassical export (Cleves et al. J Cell Biol 1996 133:1017-26).
YJL048C 0.51 1.2
YOL141W PPM2 0.51 1.4 carboxy methyl transferase; homolog of PPM1
YMR200W ROT1 0.51 1.4 Reversal of tor2 lethality
YLL043W FPS1 0.51 1.3 Suppressor of tps1/fdp1 and member of the MIP family of transmembrane channels; may be involved in glycerol efflux
YML032C RAD52 0.51 0.8 "Required for X-ray damage repair & various types of intra- and interchr. mitotic recombination, including HO switching & plasmid exchange. Disp. for premeiotic DNA synthesis, double strand breaks & heteroduplex formation."
YER056C-A RPL34A 0.51 2.3 Homology to rat L34
YIL176C 0.51 1.6
YJL223C PAU1 0.51 1.3 member of the seripauperin protein/gene family (see Gene_class PAU)
YMR173W DDR48 0.51 1.5 DNA damage inducible; implicated in the production or recovery of mutations
YIL063C YRB2 0.51 1.5 Ran-GTPase-binding protein involved in nuclear export
YLL052C AQY2 0.51 1.0 aquaporin water channel in yeast
YOR080W DIA2 0.51 1.2 Digs Into Agar
YKR015C 0.51 1.1
YNL099C OCA1 0.51 1.9 Oxidant-induced Cell-cycle Arrest 1
YOR119C RIO1 0.51 1.9 Essential in yeast; plays a role in cell cycle progression.
YKL104C GFA1 0.51 3.1 Z S catalyzes first step in hexosamine pathway required for biosynthesis of cell wall precursors
YPL190C NAB3 0.51 0.9 May be required for packaging pre-mRNAs into ribonucleoprotein structures amenable to efficient nuclear RNA processing
YBR177C EHT1 0.51 1.8 alcohol acyl transferase
YOL109W 0.51 2.1
YIR012W SQT1 0.51 1.1 Involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p
YKL212W SAC1 0.51 0.8 "Inactivation of Sac1p leads to specific increase in cellular levels of phosphatidylinositol 4-phosphate, accompanied by changes in vacuole morphology and accumulation of lipid droplets."
YBR247C ENP1 0.51 0.9 Essential nuclear protein
YGL229C SAP4 0.51 1.3 "SAP4 is related to SAP155, SAP185, and SAP190, all of which associate with the SIT4 protein phosphatase"
YGL223C COG1 0.51 0.8 Conserved Oligomeric Golgi complex 1
Complexed with Cog8p; interacts with Cog2p
YJL109C UTP10 0.51 1.8 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YDR167W TAF10 0.51 1.4 TFIID subunit (TBP-associated factor) with predicted molecular weight of 23 kD.
YOR377W ATF1 0.51 2.3 Alcohol acetyltransferase
YMR311C GLC8 0.51 1.7 Homolog of mammalian protein phosphatase inhibitor 2.
YDL020C RPN4 0.51 1.1 Involved in ubiquitin degradation pathway. May act as common transcription factor on proteasomal and proteasome-related genes.
YPL018W CTF19 0.51 1.1 Chromosome Transmission Fidelity
YJL198W PHO90 0.51 1.7 Low-affinity phosphate transporter
YLR105C SEN2 0.51 1.0 tRNA splicing endonuclease subunit
YNL265C IST1 0.51 1.3 Similar to Nuf1p (spindle pole body component)
YHR075C PPE1 0.51 2.3 carboxyl methyl esterase
YOR186W 0.50 1.4
YJR130C STR2 0.50 1.5 Sulfur TRansfer
YPL106C SSE1 0.50 1.2 "HSP70 family member, highly homologous to Ssa1p and Sse2p"
YEL049W PAU2 0.50 1.5 member of the seripauperin protein/gene family (see Gene_class PAU)
YCR035C RRP43 0.50 1.5 C Ribosomal RNA Processing
YHR078W 0.50 0.8
YBR137W 0.50 1.5
YMR110C 0.50 1.8
YGL120C PRP43 0.50 1.6 Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA
YOR384W FRE5 0.50 1.7 similar to FRE2
YGR087C PDC6 0.50 2.7 "Third, minor isozyme of pyruvate decarboxylase"
YKL107W 0.50 1.6
YHR123W EPT1 0.50 2.5 S "sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase"
YCR106W RDS1 0.50 1.7 Regulator of drug sensitivity
YOL144W NOP8 0.50 1.3 Nucleolar protein required for 60S ribosome biogenesis
YKL018W SWD2 0.50 1.0 member of Set1p complex
YGR294W 0.50 1.0
YOL073C 0.50 1.6
YPL024W NCE4 0.50 1.3 Negative regulator of Cts1 Expression
YGR286C BIO2 0.50 3.0 Biotin synthase
YPR125W 0.50 1.3
YNL009W IDP3 0.50 1.2 peroxisomal NADP-dependent isocitrate dehydrogenase
YPL152W RRD2 0.50 1.8 Resistant to Rapamycin Deletion 2
YDR533C 0.50 1.5
YDR044W HEM13 0.50 2.6 "Oxygen-repressed, sixth step in heme biosynthetic pathway"
YIL110W 0.50 1.2
YMR239C RNT1 0.50 1.3 Ribonuclease III
YML130C ERO1 0.50 1.5 "essential, FAD-dependent oxidase of protein disulfide isomerase"
YBR125C PTC4 0.50 1.8 Phosphatase type Two C
YJR032W CPR7 0.50 1.3 a cyclophilin related to the mammalian CyP-40; physically interacts with RPD3 gene product
YBR301W DAN3 0.50 1.6 delayed anaerobic gene
YBR155W CNS1 0.50 1.9 cyclophilin seven suppressor
YKL195W 0.50 1.3
YOR259C RPT4 0.50 1.0 Proteasome Cap Subunit
YKR083C DAD2 0.50 1.1 C Duo1 And Dam1 interacting; Helper of AsK1
YEL048C 0.50 0.9
YNL115C 0.50 1.8
YGL258W VEL1 0.50 2.1 Increased in velum formation in flor strain
YLL031C GPI13 0.50 2.2 Glycosylphosphatidylinositol (GPI) biosynthesis
YMR046C 0.50 0.9
YGR062C COX18 0.50 1.9 "Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space"
YKL159C RCN1 0.50 1.1 Regulator of calcineurin
YFR028C CDC14 0.50 2.1 K Required for mitosis and sporulation
YEL058W PCM1 0.50 1.8 Z Phosphoacetylglucosamine Mutase
YBR268W MRPL37 0.50 1.2 C Probable mitochondrial protein L37
YIL151C 0.50 0.9
YGR141W VPS62 0.50 0.9
YER063W THO1 0.50 1.7 Suppressor of the Transcriptional (T) defect of Hpr1 (H) by Overexpression (O)
YGR215W RSM27 0.50 0.9 mitochondrial ribosome small subunit component
YDR339C 0.50 0.9
YPL231W FAS2 0.50 1.2 Trifunctional enzyme
YEL034W HYP2 0.50 1.7 Translation initiation factor eIF-5A
YIL138C TPM2 0.50 2.1 S Tropomyosin isoform 2
YDR190C RVB1 0.50 1.5 S "RUVB-like protein, TIP49a Homologue"
YOL124C 0.50 1.5
YFL010C WWM1 0.50 1.2 WW domain containing protein interacting with Metacaspase (MCA1)
YLR141W RRN5 0.50 1.6 involved in transcription of rDNA by RNA polymerase I. UAF interacts directly with an upstream element of the promoter and mediates its stimulatory function.
YPL077C 0.50 0.8
YJR141W 0.50 1.1
YDR101C ARX1 0.50 1.4
YJR158W HXT16 0.50 1.2 hexose transporter
YKL181W PRS1 0.50 0.9 ribose-phosphate pyrophosphokinase
YML004C GLO1 0.50 1.0 Regulated by HOG (high osmolarity glycerol)-MAP (mitogen-activated protein) kinase pathway in osmotic stress response
YMR195W ICY1 0.50 1.7 Interacting with the cytoskeleton
Involved in chromatin organization and nuclear transport
Genetically interacts with TCP1 and ICY2
YLR445W 0.50 1.8
YPL224C MMT2 0.50 1.2 Protein involved in mitochondrial iron accumulation
YFR006W 0.50 1.2
YDR276C PMP3 0.50 2.3 S plasma membrane protein involved in salt tolerance
YPR116W 0.50 1.5
YLR273C PIG1 0.50 5.1 Z S C Putative type 1 phosphatase regulatory subunit; interacts with Gsy2p
YHR171W APG7 0.50 1.4 autophagy
YOR362C PRE10 0.49 1.6 proteasome component YC1 (protease yscE subunit 1)
YGL173C KEM1 0.49 0.8 Kar1-1 nuclear-fusion-defect Enhancing Mutation. Plays a role in cytoplasmic mRNA degradation.
YHL013C 0.49 1.5
YKL183W LOT5 0.49 2.4 S LOw Temperature responsive
YOR327C SNC2 0.49 1.3 mediate the targeting and transport of secretory proteins
YOR076C SKI7 0.49 1.2 Antiviral protein. Ski7p G protein appears to function as a signal-coupling factor between the two multi-complexes operating in the 3'-to-5' mRNA-decay pathway.
YPR162C ORC4 0.49 1.6 Part of complex that binds to origins of replication and thereby directs DNA replication and is also involved in transcriptional silencing
YOR027W STI1 0.49 1.9 Heat shock protein also induced by canavanine and entry into stationary phase
YGR143W SKN1 0.49 5.6 S C Involved in (1->6)-beta-glucan biosynthesis
YPL064C CWC27 0.49 1.3 Complexed with Cef1p
YEL044W IES6 0.49 1.3 Ino Eighty Subunit 6
YJL204C RCY1 0.49 1.0 ReCYcling 1
YAR028W 0.49 1.7
YGR001C 0.49 1.5
YOL152W FRE7 0.49 0.9 similar to FRE2
YLR106C MDN1 0.49 0.8 "midasin, a large protein with an N-terminal domain, a central AAA domain (with similarity to dynein) composed of 6 tandem AAA protomers, and a C-terminal M-domain containing MIDAS (Metal Ion Dependent Adhesion Site) sequence motifs"
YBR231C AOR1 0.49 1.8 C Actin Overexpression Resistant
YIL118W RHO3 0.49 2.1 ras homolog--GTP binding protein
YPL130W SPO19 0.49 2.1 sporulation-defective; SPO19 was found as a weak high-copy suppressor of the spo1-1 ts mutation. The gene is specifically induced late in meiosis (Primig et al. (2000) Nat Genet 26:415-423)
YER171W RAD3 0.49 0.9 DNA helicase component of transcription factor b (yeast homolog of human TFIIH)
YGL257C MNT2 0.49 2.1 MaNnosylTransferase; involved in adding the 4th and 5th mannose residues of O-linked glycans
YPR088C SRP54 0.49 0.8 Signal recognition particle subunit (homolog of mammalian SRP54)
YOL133W HRT1 0.49 1.3 High level expression Reduces Ty3 Transposition
YJL132W 0.49 1.4
YGR266W 0.49 1.3
YIL071C PCI8 0.49 2.2 Proteasome-COP9 signalosome-eukarytotic Initiation factor 3 (PCI) domain-containing protein
YJR097W 0.49 1.1
YGR233C PHO81 0.49 1.0 Positive regulatory protein of phosphate pathway
YJL172W CPS1 0.49 2.1 carboxypeptidase yscS
YMR251W 0.49 1.9
YOR155C 0.49 1.8
YIL073C SPO22 0.49 1.6 "sporulation-defective; SPO22 contains phospholipase A2 signature sequence (positions 135-143, found by Emotif search). The gene is specifically induced early in meiosis (Primig et al. (2000) Nat Genet 26:415-423)"
YGL131C SNT2 0.49 1.6 Hypothetical ORF
YAR044W OSH1 0.49 1.2 May be involved in ergosterol synthesis
YMR237W 0.49 1.0
YMR306W FKS3 0.49 1.2 Protein with similarity to Gls1p and Gls2p (GB:Z49212)
YBR179C FZO1 0.49 1.0 may be involved in mitochondrial fusion
YCL040W GLK1 0.49 3.7 S C Glucose phosphorylation
YER003C PMI40 0.49 4.7 Z S C catalyzes the interconversion of fructose-6-P and mannose-6-P
YOR386W PHR1 0.49 1.9 photolyase
YKR088C 0.49 1.4
YER049W 0.49 0.8
YJR109C CPA2 0.49 2.0 carbamyl phosphate synthetase
YMR250W GAD1 0.49 3.9 glutamate decarboxylase
YEL013W VAC8 0.49 0.9 An armadillo repeat-containing protein localized on the vacuolar membrane
YHR186C KOG1 0.49 0.8 Kontroller Of Growth
YIL045W PIG2 0.49 1.5 Interacts with Gsy2p
YKL085W MDH1 0.49 1.0 mitochondrial malate dehydrogenase
YDL139C SCM3 0.49 1.0 Suppressor of chromosome missegregation
YGR200C ELP2 0.49 1.2 ELongator Protein 2; 90kD subunit; has WD40 repeats
YLR432W IMD3 0.49 1.3 IMP dehydrogenase homolog
YFL011W HXT10 0.49 3.1 S high-affinity hexose transporter
YDR257C RMS1 0.49 1.7 Transcription regulator
YLR390W ECM19 0.49 1.2 ExtraCellular Mutant
YOL127W RPL25 0.49 1.7 Homology to E. coli L23 and rat L23a
YJL087C TRL1 0.49 1.2 tRNA ligase
YPL006W NCR1 0.49 0.9 Niemann-Pick Type C homologous gene
YDR197W CBS2 0.49 2.3 Translational activator of COB mRNA; soluble protein
YBR049C REB1 0.49 3.3 Z DNA binding protein which binds sites found in genes transcribed by both RNA polymerase I and RNA polymerase II. Reb1p is required for termination of RNA polymerase I transcription.
YDL115C IWR1 0.49 0.9 Interacts with RNA Polymearse II
YPL095C 0.49 2.5 Z S
YOR179C 0.49 1.3
YKL091C 0.49 2.4
YKL191W DPH2 0.49 1.6 "Diptheria toxin resistance protein, required for diphthamide biosynthesis"
YPL086C ELP3 0.49 1.2 elongator protein; histone and other protein acetyltransferase; has sequence homology to known HATs and NATs
YMR191W 0.49 1.7
YIL030C SSM4 0.49 1.8 Protein involved in mRNA turnover
YKL154W SRP102 0.49 1.1 Signal recognition particle receptor beta subunit
YNL316C PHA2 0.49 0.9 prephenate dehydratase
YML103C NUP188 0.49 1.6 Localized at both the cytoplasmic and nucleoplasmic faces of the nuclear pore complex (NPC); may form the octagonal core structure of NPC
YCL031C RRP7 0.49 1.5 involved in rRNA processing
YPL229W 0.49 0.9
YJR121W ATP2 0.49 1.3 "F(1)F(0)-ATPase complex beta subunit, mitochondrial"
YBR234C ARC40 0.49 1.6 "Arp2/3 complex subunit, 40 kilodalton"
YPL004C 0.49 2.5 C
YOR280C FSH3 0.49 1.2
YBL049W 0.49 1.8
YDR402C DIT2 0.49 1.5 Disp. for spores & spore viab. - required for dityrosine biosynth. & dityrosine accumul. in outer spore wall (s.w.); s.w. matur. & resist. to ether & lytic enz. mRNA trans. mid/late during s.w. formation
YGR134W CAF130 0.49 0.9 CCR4 Associated Factor 130 kDa
YHR160C PEX18 0.49 2.0 Peroxin; Pex18p and Pex21p are partially functionally redundant.
YLR125W 0.49 1.3
YKL001C MET14 0.49 4.0 S adenylylsulfate kinase
YNL258C DSL1 0.49 1.5 "dsl1 mutations are suppressed by a dominant allele of SLY1, called sly1-20"
YPR186C PZF1 0.49 1.0 Transcription factor IIIA (TFIIIA) with putative Zn-fingers
YCR037C PHO87 0.49 2.7 May collaborate with Pho86p and Pho84p in inorganic phosphate uptake; protein contains 12 predicted transmembrane domains
YDR496C PUF6 0.49 1.0 member of the PUF protein family
YBL042C FUI1 0.49 1.1 uridine permease
YDL093W PMT5 0.49 3.1 Z S C Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway
YKL009W MRT4 0.49 1.5 mRna turnover 4
YGR052W 0.49 1.9
YLR108C 0.49 1.7
YLR401C 0.49 1.1
YKR090W PXL1 0.49 2.6 S Paxillin-like protein 1
YBR235W 0.49 1.1
YJR149W 0.49 2.2
YGL016W KAP122 0.49 1.1 Member of the karyopherin-beta family with possible role in nuclear transport and regulation of pleiotropic drug resistance.
YGR099W TEL2 0.49 3.5 Z S Involved in controlling telomere length
YGR204W ADE3 0.49 0.9 "Required for the biosynthesis of purines, thymidylate, methionine, histidine, pantothenic acid and formylmethionyl-tRNA"
YCR098C GIT1 0.49 2.4 permease involved in the uptake of glycerophosphoinositol (GroPIns)
YHL025W SNF6 0.49 1.4 Involved in global regulation of transcription
YOR144C ELG1 0.48 3.0 Z S C "Enhanced Level of Genomic instability, Repressor of Ty1 Transposition"
YER157W COG3 0.48 1.6 Conserved Oligomeric Golgi complex 3
secretion (golgi retention) deficient
YJR040W GEF1 0.48 1.0 "Integral membrane protein highly homologous to voltage-gated chloride channels from humans, mice and fish"
YGL242C 0.48 1.7
YOR123C LEO1 0.48 1.1 member of the RNA polymerase II-associated Paf1 complex
YFR020W 0.48 1.5
YPL239W YAR1 0.48 1.2 YAR1 encodes a 200-amino-acid protein with two ANK repeat motifs and an acidic C terminus rich in PEST-like sequences
YDR376W ARH1 0.48 1.3 adrenodoxin oxidoreductase homolog
YMR062C ECM40 0.48 1.3 ExtraCellular Mutant
YDL230W PTP1 0.48 1.7 phosphotyrosine-specific protein phosphatase
YDR329C PEX3 0.48 1.1 48-kDa peroxisomal integral membrane protein
YDR045C RPC11 0.48 0.9 TFIIS-like small Pol III subunit C11
YBR002C RER2 0.48 1.4 cis-prenyltransferase involved in dolichol synthesis
YCR068W CVT17 0.48 1.4 Cytoplasm to vacuole targeting mutant
YNL259C ATX1 0.48 1.8 "antioxidant protein and metal homeostasis factor, protects against oxygen toxicity"
YBR241C 0.48 2.0
YLL064C 0.48 1.5
YNR076W PAU6 0.48 1.6 member of the seripauperin protein/gene family
YDR289C RTT103 0.48 1.9 Regulator of Ty1 Transposition
YLR233C EST1 0.48 2.1 S C Telomere elongation protein (ever shorter telomeres)
YML126C ERG13 0.48 1.5 involved in mevalonate synthesis
YPR035W GLN1 0.48 2.2 glutamine synthetase
YOR356W 0.48 1.1
YPL170W 0.48 1.7
YOR299W BUD7 0.48 0.8 bud site selection
YGR088W CTT1 0.48 0.8 cytoplasmic catalase T
YDR205W MSC2 0.48 1.4 Meiotic Sister-Chromatid recombination; transmembrane protein (putative) showing some protein similarity to Zrc1p and Cot1p
YJR047C ANB1 0.48 2.4 hypusine containg protein; ANB1 is expressed under anaerobic conditions and repressed under aerobic conditions whereas its homolog HYP2 is inversely regulated
YLL055W 0.48 1.4
YOL101C 0.48 4.9 S
YGL031C RPL24A 0.48 1.7 Homology to rat L24
YFR030W MET10 0.48 2.3 S subunit of assimilatory sulfite reductase
YIR009W MSL1 0.48 1.3 involved in splicing
YAL054C ACS1 0.48 1.4 one of 2 acetyl-coA synthetases in yeast
YDL106C PHO2 0.48 0.8 Regulation of phosphate metabolism
YLR437C 0.48 3.4 Z S
YJR161C COS5 0.48 1.2 "Protein with similarity to members of the Ybr302p/Ycr007p/Cos8p/Cos9p family, coded from subtelomeric region"
YKR100C 0.48 0.9
YFL003C MSH4 0.48 1.6 "dispensable for DNA repair, required for full levels of reciprocal exchange and spore viability"
YMR017W SPO20 0.48 1.8 DBF2 Interacting Protein; SNAP 25 homolog
YAL014C SYN8 0.48 1.4 "SNARE protein releated to mammalian SYNtaxin 8, ULP1 Interacting Protein 2"
YMR162C DNF3 0.48 1.3 Drs2 Neo1 Family
YOR075W UFE1 0.48 2.0 S t-SNARE that resides on the endoplasmic reticulum and mediates retrograde traffic from the Golgi complex
YDL132W CDC53 0.48 1.4 "acts together with Cdc4p and Cdc34p to control the G1-S phase transition, assists in mediating the proteolysis of the Cdk inhibitor Sic1p in late G1"
YNL273W TOF1 0.48 3.6 Z S C topoisomerase I interacting factor 1
YOL024W 0.48 1.5
YHR001W OSH7 0.48 0.9 Oxysterol Binding Protein
YHL022C SPO11 0.48 1.7 "Dispensable for mitosis, premeiotic DNA synthesis, spindle pole body duplication, meiosis I, meiosis II & spores. Required for chromosome pairing seen by in situ hybridization, double strand breaks, synaptonemal complexes."
YDR303C RSC3 0.48 1.7 Zinc cluster protein
YMR033W ARP9 0.48 1.5 involved in transcriptional regulation
YHR045W 0.48 0.9
YLR283W 0.48 0.9
YDL223C HBT1 0.48 0.9 Hub1 target
YJR003C 0.48 2.5 S
YDL109C 0.48 0.8
YOR189W IES4 0.48 1.1 Ino Eighty Subunit 4
YNL297C MON2 0.48 1.0 protein with similarity to N-terminal region of the human protein BIG1
YGR229C SMI1 0.48 0.9 "Protein involved in (1,3)-beta-glucan synthesis, possibly through regulation of cell wall glucan and chitin synthesis; chromatin binding protein"
YOL088C MPD2 0.48 1.8 S protein disulfide isomerase related protein
YPL247C 0.48 2.7
YCR072C 0.48 1.1
YPR168W NUT2 0.48 1.9 Negative regulator of URS2 of the HO promoter
YOL114C 0.48 2.4 S
YDR380W ARO10 0.48 1.7 S
YPL013C 0.48 1.0
YLR341W SPO77 0.48 1.4 Sporulation
YOL129W VPS68 0.48 1.4
YPR195C 0.48 0.8
YNR063W 0.48 1.1
YDR058C TGL2 0.48 1.5 Triglyceride Lipase
YPL015C HST2 0.48 2.0 Homolog of SIR2
YDR041W RSM10 0.48 1.2 mitochondrial ribosome small subunit component
YLR024C UBR2 0.48 1.4 ubiquitin-protein ligase (E3)
YBR005W 0.48 1.8
YLR433C CNA1 0.48 1.0 calmodulin binding protein homologous to mammalian calcineurin
YGL202W ARO8 0.48 0.8 aromatic amino acid aminotransferase
YAR027W UIP3 0.48 1.2 Ulp1 Interacting Protein 3
YLR015W BRE2 0.48 1.0 C "putative transcription factor, contains a PHD finger motif; homology to D. melanogaster Ash2p trithorax transcription factor
member of Set1p complex"
YAR042W SWH1 0.48 1.9 Similar to mammalian oxysterol-binding protein
YLR359W ADE13 0.48 1.3 Adenylosuccinate Lyase
YJL082W IML2 0.48 1.3 Similar to Ykr018p
YOR360C PDE2 0.48 1.9 low-Km (high-affinity) cAMP phosphodiesterase
YPR140W 0.48 2.0
YOR304W ISW2 0.48 1.2 has strong homology to Drosophila ISWI
YDL243C AAD4 0.48 1.2 high degree of similarity with the AAD of P. chrysosporium
YGR173W 0.48 1.4
YBL037W APL3 0.48 3.8 clathrin Associated Protein complex Large subunit
YDR111C 0.48 1.4
YFR017C 0.48 2.8 C
YER122C GLO3 0.48 2.0 Zinc-finger-containing protein with similarity to Gcs1p and Sps18p
YAL068C 0.48 1.4
YFR055W 0.48 2.0
YMR029C 0.48 1.7
YDR394W RPT3 0.48 1.3 probable 26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases
YKL173W SNU114 0.48 1.1 involved in splicing
YLR373C VID22 0.47 3.1 Z S Vacuole import and degradation
YAR075W 0.47 1.2
YLR321C SFH1 0.47 1.2 "Involved in chromatin modeling, cell cycle progression"
YLR429W CRN1 0.47 0.8 "coronin, an actin-binding protein originally identified in Dictyostelium"
YGR120C COG2 0.47 1.9 Conserved Oligomeric Golgi complex 2
Secretion deficient
YIR021W MRS1 0.47 1.9 RNA splicing protein of the mitochondrial carrier (MCF) family
YJL029C VPS53 0.47 1.4 Required for Vacuolar Protein Sorting
YPR016C TIF6 0.47 1.4 "similar to human translation initiation factor 6 (eIF6); however, TIF6 does not act as a true translation initiation factor.The protein may be involved in the biogenesis and or stability of the 60S ribosomal subunits"
YMR243C ZRC1 0.47 1.7 Zinc- and cadmium-resistance protein
YDR516C EMI2 0.47 2.3 Early Meiotic Induction
YDR532C KRE28 0.47 1.3 Killer toxin REsistant
YDL245C HXT15 0.47 1.2 High-affinity hexose transporter
YDR162C NBP2 0.47 0.9 "interacts with Nap1, which is involved in histone assembly"
YJL125C GCD14 0.47 1.9 General Control Derepression
YHR163W SOL3 0.47 1.4 weak multicopy suppressor of los1-1
YML080W DUS1 0.47 0.8 tRNA dihydrouridine synthase
YLR116W MSL5 0.47 1.4 branchpoint bridging protein -- component of the splicing commitment complex
YHL009C YAP3 0.47 1.1 bZIP protein; transcription factor
YOR128C ADE2 0.47 1.5 phosphoribosylamino-imidazole-carboxylase
YLR137W 0.47 1.5
YBL051C PIN4 0.47 3.4 [PSI+] induction
YGL025C PGD1 0.47 0.8 "Probable transcription factor, polyglutamine domain protein"
YML074C FPR3 0.47 1.2 "binds the immunosuppressant drugs, FK506 and rapamycin, and is localized to the nucleolus; binds to nuclear localization signal-containing peptides in vitro"
YKR079C 0.47 1.6 S
YJL133W MRS3 0.47 1.0 mitochondrial carrier protein
YBL091C MAP2 0.47 0.8 methionine aminopeptidase 2
YOR032C HMS1 0.47 1.3 High-copy mep2 suppressor
YBR192W RIM2 0.47 1.4 Protein of the mitochondrial carrier (MCF) family that is required for respiration
YNL021W HDA1 0.47 1.7 component of histone deacetylase A
YKR002W PAP1 0.47 1.0 poly(A) polymerase
YGL253W HXK2 0.47 1.5 Glucose phosphorylation
YIL034C CAP2 0.47 0.8 capping - addition of actin subunits
YER139C 0.47 2.6
YDR158W HOM2 0.47 1.6 threonine and methionine pathway
YOR063W RPL3 0.47 1.6 Homology to rat L3
YKL089W MIF2 0.47 2.7 S centromere protein required for normal chromosome segregation and spindle integrity
YGL114W 0.47 1.9
YNL207W RIO2 0.47 1.0 Protein required for cell viability
YML070W DAK1 0.47 1.6 putative dihydroxyacetone kinase
YKL148C SDH1 0.47 1.7 "Yeast succinate dehydrogenase (SDH) is a tetramer of non-equivalent subunits--Sdh1p, Sdh2p, Sdh3p, Sdh4p--that couples the oxidation of succinate to the transfer of electrons to ubiquinone."
YDR198C 0.47 1.3
YDL146W 0.47 1.4
YKL210W UBA1 0.47 1.0 similar to Uba2p
YDR300C PRO1 0.47 1.2 catalyzes first step in proline biosynthesis
YLR004C 0.47 1.7
YKR065C 0.47 0.9
YCL058C FYV5 0.47 1.2 Function required for Yeast Viability on toxin exposure
YLR399C BDF1 0.47 1.5 "Required for sporulation, possible component of chromatin; affects synthesis of snRNA"
YPR014C 0.47 2.6 S
YBR289W SNF5 0.47 1.2 Involved in global regulation of transcription
YEL011W GLC3 0.47 2.2 Glycogen branching enzyme
YPL116W HOS3 0.47 4.5 Z S C "Protein with similarity to Hda1p, Rpd3p, Hos2p, and Hos1p"
YBR050C REG2 0.47 1.3 Possible regulatory subunit for the PP1 family protein phosphatase Glc7p
YBR238C 0.47 2.4
YLR129W DIP2 0.47 1.5 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); DOM34 Interacting Protein
YPL176C 0.47 1.1
YJL196C ELO1 0.47 3.0 S C "elongation enzyme 1, required for the elongation of the saturated fatty acid tetradecanoic acid (14:0) to that of hexadecanoic acid (16:0)"
YGL110C CUE3 0.47 0.8 Hypothetical ORF
YNL104C LEU4 0.47 0.9 leucine biosynthesis
YGL190C CDC55 0.47 1.1 Involved in cellular morphogenesis
YER120W SCS2 0.47 2.0 "Suppressor of Choline Synthesis
Likely to be involved in regulating INO1 expression, suppressor of a dominant nuclear mutation that is inositol-dependent in the presence of choline"
YGL036W 0.47 1.6
YOL095C HMI1 0.47 1.3 Helicase in MItochondria
YGR236C SPG1 0.47 2.1 Hypothetical ORF
YDL134C PPH21 0.47 1.1 serine-threonine protein phosphatase 2A
YPL265W DIP5 0.47 2.9 S dicarboxylic amino acid permease
YNL325C FIG4 0.47 0.9 FIG4 expression is induced by mating factor.
YMR304W UBP15 0.47 0.8 putative deubiquitinating enzyme
YDL186W 0.47 1.3
YFL053W DAK2 0.47 2.3 dihydroxyacetone kinase
YMR167W MLH1 0.47 1.0 "Required for mismatch repair in mitosis and meiosis, low levels of postmeiotic segregation, and high spore viability"
YDR151C CTH1 0.47 1.2 RNA triphosphatase/NTPase
YEL019C MMS21 0.47 1.2 Protein involved in DNA repair
YJL100W LSB6 0.47 0.9 LAs17 Binding protein
YPR161C SGV1 0.47 0.9 CDC28/cdc2 related protein kinase
YKL178C STE3 0.47 3.7 S The a factor receptor encoded by the STE3 gene allows yeast cells of the Alpha mating type to recognize cells of the a mating type
YLR351C NIT3 0.47 1.7 "Nit protein, nitrilase superfamily member"
YGR116W SPT6 0.47 1.1 may be involved in transcription elongation by mediating interactions between RNA polymerase II and chromatin
YLR314C CDC3 0.47 1.7 involved in proper bud growth
YGR061C ADE6 0.47 1.1 5'-phosphoribosylformyl glycinamidine synthetase
YBL046W 0.47 1.0
YIL032C 0.47 1.9
YBR188C NTC20 0.47 0.8 Prp19p (NineTeen)-associated Complex protein
YMR094W CTF13 0.47 2.0 "58 kd component (Cbf3c) of the multisubunit 'Cbf3' kinetochore protein complex, which binds to the CDE III element of centromeres"
YPL209C IPL1 0.47 3.0 S C Regulation of yeast chromosome segregation
YBR066C NRG2 0.47 2.1 homologue of NRG1
YCR016W 0.47 1.1
YDR080W VPS41 0.47 1.7 vacuolar protein sorting
YGL087C MMS2 0.47 0.8 Member of error-free postreplication DNA repair pathway
YNL006W LST8 0.47 0.8 Required for amino acid permease transport from the Golgi to the cell surface
YOR085W OST3 0.47 1.8 Catalyzes the transfer of oligosaccharide from dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synth. proteins - ER lumen; may enhance oligosacch. transfer to subset of acceptor substrates
YOR313C SPS4 0.46 3.9 S sporulation-specific protein
YNL222W SSU72 0.46 0.9 "functionally related to TFIIB, affects start site selection in vivo"
YGR174C CBP4 0.46 1.2 Essential for the expression and activity of ubiquinol-cytochrome c reductase
YDR459C 0.46 1.9
YBR152W SPP381 0.46 2.7 Suppressor of Pre-mRNA Processing mutant
YKR048C NAP1 0.46 0.8 nucleosome assembly protein I
YGR096W TPC1 0.46 1.1 thiamine pyrophosphate carrier
YLR266C PDR8 0.46 1.8 Pleiotropic Drug Resistance
YDR018C 0.46 2.2
YJR016C ILV3 0.46 1.1 catalyzes third step in common pathway leading to biosynthesis of branched-chain amino acids
YGR063C SPT4 0.46 0.8 "Zn-finger protein, transcriptional regulator"
YAL064W 0.46 1.4
YBL039C URA7 0.46 1.9 Last step in pyrimidine biosynthesis pathway; URA7 is very similar to URA8 CTP synthase
YCR051W 0.46 0.8
YFL063W 0.46 1.2
YGR281W YOR1 0.46 1.0 C multispecific organic anion transporter important for tolerance against toxic environmental organic anions
YOR177C MPC54 0.46 2.5 Meiotic Plaque Component
YKL140W TGL1 0.46 1.0 triglyceride lipase-cholesterol esterase
YNL123W 0.46 1.6
YMR044W IOC4 0.46 1.0 Iswi One Complex
YLL058W 0.46 2.1
YOL067C RTG1 0.46 1.8 "Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus"
YIL029C 0.46 1.2
YMR065W KAR5 0.46 2.2 appears to be required for the completion of nuclear membrane fusion and may play a role in the organization of the membrane fusion complex
YKR054C DYN1 0.46 2.1 Dynein
YER045C ACA1 0.46 1.8 contains an ATF/CREB-like bZIP domain; transcriptional activator
YJL089W SIP4 0.46 2.0 Possibly involved in Snf1p regulated transcriptional activation
YLR114C 0.46 1.5
YMR113W FOL3 0.46 1.0 FOLinic acid requiring
YGL130W CEG1 0.46 0.8 "mRNA guanylyltransferase (mRNA capping enzyme), alpha subunit"
YDR107C 0.46 1.0
YKL010C UFD4 0.46 1.0 Ubiquitin Fusion Degradation
YLL057C 0.46 1.2
YGR049W SCM4 0.46 1.2 Protein that suppresses ts allele of CDC4 when overexpressed
YHR021W-A ECM12 0.46 2.7 ExtraCellular Mutant
YJR090C GRR1 0.46 1.0 F box protein with several leucine rich repeats
YOL104C NDJ1 0.46 1.8 Involved in meiotic chromosome segregation; may stabilize homologus DNA interactions at telomeres and is required for a telomere activity in distributive segregation; is associated with telomeres
YPR073C LTP1 0.46 1.1 Homologous to mammalian phosphotyrosine phosphatase
YMR205C PFK2 0.46 0.8 phosphofructokinase beta subunit
YCL009C ILV6 0.46 1.2 acetolactate synthase regulatory subunit
YDL126C CDC48 0.46 1.4 "Microsomal protein of CDC48/PAS1/SEC18 family of ATPases; full length homology to mammalian protein VCP; involved in secretion, peroxisome formation and gene expression"
YPL278C 0.46 1.1
YDR024W FYV1 0.46 1.7 Function required for Yeast Viability on toxin exposure
YMR186W HSC82 0.46 1.3 constitutively expressed heat shock protein
YIL051C MMF1 0.46 1.7 Maintenance of Mitochondrial Function
YHL032C GUT1 0.46 1.2 Glycerol utilization
YIL155C GUT2 0.46 2.0 "glycerol-3-phosphate dehydrogenase, mitochondrial"
YOR250C CLP1 0.46 2.0 S cleavage/polyadenylation factor IA subunit; interacts with Pcf11p in the 2-hybrid system
YPR144C UTP19 0.46 0.9 "U3 protein, localized to the nucleolus"
YBR163W DEM1 0.46 0.8 weak similarity to Pta1p (pre-tRNA processing protein)
YER175C TMT1 0.46 1.4 Trans-aconitate Methyltransferase 1
YGL147C RPL9A 0.46 1.1 Homology to rat L9
YBL022C PIM1 0.46 1.0 mitochondrial ATP-dependent protease
YNL091W NST1 0.46 0.9 Negative affector of Salt Tolerance
YIL093C RSM25 0.46 1.0 mitochondrial ribosome small subunit component
YLR213C CRR1 0.46 1.0 CRH-Related
YFR039C 0.46 2.5 Z S
YKL139W CTK1 0.46 1.0 putative kinase subunit of the kinase complex that phosphorylates the RPO21 CTD (carboxy-terminal domain); also called CTDK-I alpha subunit
YDR411C 0.46 1.0
YOR051C 0.46 1.4
YLR134W PDC5 0.46 1.5 pyruvate decarboxylase
YOR196C LIP5 0.46 0.9 Involved in lipoic acid metabolism
YOR132W VPS17 0.46 2.8 Peripheral membrane protein required for vacuolar protein sorting
YOR036W PEP12 0.46 2.2 integral membrane protein; c-terminal TMD; located in endosome
YGL118C 0.46 1.4
YLR281C 0.46 1.3 C
YGL019W CKB1 0.46 1.0 beta (38kDa) subunit of protein kinase CK2
YDR061W 0.46 1.3
YCR017C CWH43 0.46 1.2
YBR269C 0.46 1.3
YOR215C 0.46 1.9
YNL097C PHO23 0.46 1.4 Involved in expression of PHO5
YFL057C 0.46 1.3
YOR002W ALG6 0.46 1.0 Required for glucosylation in the N-linked glycosylation pathway
YMR221C 0.46 0.9
YLR449W FPR4 0.46 1.5 "Homolog of homolog of the nucleolar FKBP, Fpr3"
YOL014W 0.46 3.0 S C
YPR021C 0.46 1.6
YHR042W NCP1 0.46 1.6 NADP-cytochrome P450 reductase
YPL174C NIP100 0.46 1.6 Nuclear import protein
YFR045W 0.46 1.1
YHR164C DNA2 0.45 0.8 DNA replication helicase
YNL307C MCK1 0.45 1.7 "Disp. for mitosis, required for chr. segregation, benomyl resist., basal IME1 transcript. in mitosis, IME1 induction in meiosis & ascus mat. independ. of IME1; maybe in mitotic chr. segregation specific to CDEIII"
YLR422W 0.45 1.3
YMR266W RSN1 0.45 1.5 overexpression Rescues sro7/sop1 in NaCl
YER098W UBP9 0.45 1.6 similar to Ubp13p
YLR446W 0.45 1.2
YDR448W ADA2 0.45 1.8 S "transcription factor, member of ADA and SAGA, two transcriptional adaptor/HAT (histone acetyltransferase)complexes"
YKR053C YSR3 0.45 1.8 Yeast Sphingolipid Resistance Gene
YNL133C FYV6 0.45 1.4 Function required for Yeast Viability on toxin exposure
YHR033W 0.45 0.9
YIR018W YAP5 0.45 1.2 bZIP protein; transcription factor
YKL125W RRN3 0.45 0.8 Required for transcription of rDNA by RNA Polymerase I
YDR272W GLO2 0.45 2.0 Cytoplasmic glyoxylase-II
YDR098C GRX3 0.45 1.6 "Member of a glutaredoxin subfamily in Sc together with GRX4 & GRX5. Sign. sequence diff. with the other glutaredoxin subfamily, formed by the previously described GRX1 & GRX2 glutaredoxins (Luikenhuis MBC 9:1081, 1998)"
YOR110W TFC7 0.45 1.2 Transcription factor for RNA polymerase III
YPR103W PRE2 0.45 1.9 responsible for the chymotryptic activity of the yeast 20S proteasome
YPR152C 0.45 1.3
YJR148W BAT2 0.45 3.7 S C Branched-Chain Amino Acid Transaminase
YPL236C 0.45 1.0
YJL108C PRM10 0.45 1.3 pheromone-regulated membrane protein
YAL059W ECM1 0.45 1.4 putative transmembrane domain protein involved in cell wall biogenesis
YCL043C PDI1 0.45 1.8 S Catalyzes the formation and isomerization of disulfide bonds during the folding of secretory proteins.
YPL189W GUP2 0.45 1.1 Involved in active glycerol uptake
YPL057C SUR1 0.45 4.3 S C Involved in maintenance of phospholipid levels
YPR193C HPA2 0.45 1.8 Histone and other Protein Acetyltransferase; Has sequence homology to known HATs and NATs
YDR353W TRR1 0.45 2.1 S Thioredoxin reductase
YJL017W 0.45 2.5
YNL040W 0.45 0.8
YDR139C RUB1 0.45 1.0 Related to ubiquitin (53% identical). Homolog of mammalian ubiquitin-like protein NEDD8. Matures by proteolytic removal of C-terminal asparagine (ASN) residue. Requires the proteins ULA1 & UBA3 for activation
YBR199W KTR4 0.45 1.0 "Putative alpha-1,2-mannosyltransferase"
YNL308C KRI1 0.45 1.1 KRRI-Interacting protein 1
YDL036C 0.45 1.3
YGR060W ERG25 0.45 1.3 membrane-bound non-heme di-iron oxygenase involved in lipid metabolism.
YMR152W YIM1 0.45 1.9 "Mitochondrial inner membrane protease, similar to E. coli leader peptidase"
YPL104W MSD1 0.45 1.3 "Aspartyl-tRNA synthetase, mitochondrial"
YKL098W 0.45 1.0
YDR035W ARO3 0.45 1.3 "DAHP synthase; a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited; phospho-2-keto-3-deoxyheptonate aldolase; 2-dehydro-3-deoxyphosphoheptonate aldolase; 3-deoxy-D-arabine-heptulosonate-7-phosphate synthase"
YOR284W 0.45 2.8 C
YLR299W ECM38 0.45 1.7 ExtraCellular Mutant; cik1 suppressor
YLR020C 0.45 0.8
YJR005W APL1 0.45 1.7 "beta-adaptin, large subunit of the clathrin-associated protein complex"
YHL030W ECM29 0.45 1.6 ExtraCellular Mutant
YDR383C NKP1 0.45 1.8 C Non-essential kinetochore protein
YER061C CEM1 0.45 1.3 homology with beta-keto-acyl synthases
YNL304W YPT11 0.45 2.4 S C similar to Ypt1 and other Ras-like GTP-binding proteins
YMR039C SUB1 0.45 1.5 Suppressor of TFIIB mutations
YOR049C RSB1 0.45 2.6 S Resistance to Sphingoid long-chain Base. Putative transporter or flippase that translocates LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane.
YOR305W 0.45 1.6
YDR202C RAV2 0.45 1.5 Regulator of (H+)-ATPase in Vacuolar membrane
YLL011W SOF1 0.45 0.9 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); 56 kDa nucleolar snRNP protein that shows homology to beta subunits of G-proteins and the splicing factor Prp4
YPL091W GLR1 0.45 1.7 converts oxidized glutathine and NADPH into two glutathiones and NADP+
YPL173W MRPL40 0.45 1.4 Mitochondrial ribosomal protein MRPL40 (YmL40)
YDR174W HMO1 0.45 0.9 High mobility group (HMG)-like protein
YKL041W VPS24 0.45 1.0 involved in secretion
YKL213C DOA1 0.45 1.3 Required for normal intracellular ubiquitin metabolism and for normal rates of proteolysis of ubiquitin-dependent proteolytic substrates in vivo
YKL119C VPH2 0.45 1.2 "Required for the biogenesis of a functional vacuolar ATPase (V-ATPase), but not part of the final enzyme complex."
YDL215C GDH2 0.45 1.3 NAD-dependent glutamate dehydrogenase
YNL102W POL1 0.45 5.1 K S C "Required for mitotic DNA synthesis, premeiotic DNA synthesis, recombination, and full sporulation"
YGR047C TFC4 0.45 1.3 transcription factor tau (TFIIIC) subunit 131
YFL055W AGP3 0.45 1.2 The acronym may be misleading. AGP3 has not been shown to be a general amino acid permease with broad substrate specificity
YAL003W EFB1 0.45 2.2 "Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p"
YDR391C 0.45 1.9
YGL137W SEC27 0.45 1.2 Involved in endoplasmic-to-Golgi protein trafficking
YLR060W FRS1 0.45 1.0 "Phenylalanyl-tRNA synthetase, alpha subunit, cytoplasmic"
YLR216C CPR6 0.45 1.9 a cyclophilin related to the mammalian CyP-40; physically interacts with RPD3 gene product
YNL079C TPM1 0.45 1.2 tropomyosin I
YOR183W FYV12 0.45 2.1 Function required for Yeast Viability on toxin exposure
YFR018C 0.45 1.1
YCL005W 0.45 1.8
YHR041C SRB2 0.45 1.1 RNA polymerase II holoenzyme/mediator subunit
YLR200W YKE2 0.45 1.0 Yeast nuclear gene encoding a protein showing homology to mouse KE2 and containing a putative leucine-zipper motif
YJR001W 0.45 3.3 S
YML069W POB3 0.45 1.5 binds to catalytic subunit of DNA polymerase alpha (Pol1p)
YHR023W MYO1 0.45 5.5 S C myosin class II
YDL166C FAP7 0.45 0.8 Nuclear protein involved in oxidative stress response
YGR017W 0.45 2.1
YDR485C VPS72 0.45 1.0
YDR214W AHA1 0.45 1.8 Activator of Heat Shock Protein 90 ATPase
YPL216W 0.45 0.8
YOR038C HIR2 0.45 1.7 Involved in cell-cycle regulation of histone transcription
YNL317W PFS2 0.45 1.3 Polyadenylation Factor I subunit 2
YJR063W RPA12 0.45 1.4 A12.2 subunit of RNA polymerase I
YOR188W MSB1 0.45 3.4 S C Protein that may play a role in polarity establishment and bud formation
YOL132W GAS4 0.45 4.0 S Hypothetical ORF
YJR094C IME1 0.45 1.4 Transcriptional activator of meiotic gene expression.
YKL058W TOA2 0.45 1.0 "Transcription factor IIA, small chain"
YCR004C YCP4 0.45 1.4 Protein with similarity to S. pombe brefeldin A resistance protein obr1 and E. coli WrbA protein which stimulates binding of Trp repressor to DNA
YPL222W 0.45 3.0
YIL126W STH1 0.45 1.9 C "helicase related protein, snf2 homolog"
YPL126W NAN1 0.45 1.0 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); Net1-Associated Nucleolar protein 1
YPL208W 0.45 4.1 Z S C
YDR410C STE14 0.45 1.4 farnesyl cysteine-carboxyl methyltransferase
YPR159W KRE6 0.45 2.3 K S cell wall beta-glucan assembly
YPL098C 0.45 1.4
YBR196C PGI1 0.45 2.0 Phosphoglucoisomerase
YML031W NDC1 0.45 1.2 "dispensable for mitotic spindle pole body duplication, but required for insertion of nascent spindle pole bodies into the nuclear envelope. ndc1 parental spindle pole bodies form monopolar spindles in mitosis. Required for meiosis II."
YDL051W LHP1 0.45 1.0 Protein homologous to human La (SS-B) autoantigen
YDR525W API2 0.45 1.9 APIcal 2
YNL173C MDG1 0.45 2.8 S C "multicopy suppressor of bem1 mutation, may be involved in G-protein mediated signal transduction; binds cruciform DNA"
YDR246W TRS23 0.45 1.2 Trapp subunit of 23 kDa
YLL032C 0.45 5.3 Z S
YPR134W MSS18 0.45 1.4 Protein involved in splicing intron a15beta of COX1
YNR049C MSO1 0.45 0.8 "multicopy suppressor of sec1; small hydrophilic protein, enriched in microsomal membrane fraction, interacts with Sec1p"
YOL064C MET22 0.45 2.0 Putative phosphatase gene involved in salt tolerance and methionine biogenesis; halotolerance
YDR096W GIS1 0.45 1.3 putative zinc finger protein; repressor of PHR1 transcription
YEL075C 0.45 4.8 Z S
YDL169C UGX2 0.45 3.1 S Product of gene unknown
YKL165C MCD4 0.45 3.7 Z S C Required for GPI anchor synthesis
YLR368W MDM30 0.44 1.2 "F-box protein, loss of mitochondrial function.
Mitochondrial Distribution and Morphology"
YLR084C RAX2 0.44 2.6 S Involved in the maintenance of bipolar pattern
YER118C SHO1 0.44 3.5 Z S C Transmembrane osmosensor (structurally unrelated to SLN1) with four transmembrane segments & a cytoplasmic SH3-domain. The SH3-domain interacts with a proline-rich motif in the N-terminal region of Pbs2p (a MAP kinase kinase homolog)
YMR297W PRC1 0.44 2.2 "dispensable for haploidization and sporulation, but required for full protein degradation during sporulation"
YAL064C-A 0.44 1.1
YJL114W 0.44 2.5
YNL246W VPS75 0.44 0.9
YDR519W FPR2 0.44 0.9 binds the immunosuppressant drug FK506
YBR127C VMA2 0.44 0.9 "vacuolar H-ATPase regulatory subunit (subunit b), 60 kDa subunit of V1 sector"
YMR124W 0.44 1.1
YML075C HMG1 0.44 1.5 Induces cell to assemble stacks of paired nuclear-associated membranes called karmellae.
YAL067C SEO1 0.44 3.2 S Suppressor of Sulfoxyde Ethionine resistance
YDL100C ARR4 0.44 1.3 provides low levels of resistance to arsenicals
YFL037W TUB2 0.44 3.6 Z S beta subunit of tubulin monomer; involved in chromosome segregation and nuclear migration
YDL111C RRP42 0.44 1.0 Ribosomal RNA Processing
YDR143C SAN1 0.44 0.9 (putative) transcriptional regulator
YLR272C YCS4 0.44 1.7 loss of cohesion
YOL098C 0.44 1.2
YDL165W CDC36 0.44 1.1 Required for Start B in mitosis and for meiosis I spindle pole body separation
YDR535C 0.44 2.3
YBR106W PHO88 0.44 1.2 May be a membrane protein involved in inorganic phosphate transport and regulation of Pho81p function
YMR063W RIM9 0.44 1.2 Regulator of IME2 (RIM)
required for IME1 expression
YIL075C RPN2 0.44 0.8 involved in tRNA processing and degradation of ubiquitinated proteins
YER004W 0.44 2.1
YOR394W 0.44 2.1
YPL282C 0.44 0.9
YOR199W 0.44 1.4
YPR047W MSF1 0.44 2.2 alpha subunit of yeast mitochondrial phenylalanyl-tRNA synthetase
YMR127C SAS2 0.44 1.5 "Protein involved in silencing HMR, homologous to acetyltransferases"
YGL144C 0.44 1.9
YHR205W SCH9 0.44 2.1 S "protein kinase involved in growth control, may be redundant with cAMP pathway"
YJR138W IML1 0.44 1.3 Product of gene unknown
YKL047W 0.44 2.3
YOR003W YSP3 0.44 1.2 subtilisin-like protease III
YNL318C HXT14 0.44 1.6 High-affinity hexose transporter
YDR328C SKP1 0.44 1.6 Involved in kinetochore function and ubiquitin-mediated proteolysis
YER178W PDA1 0.44 1.1 alpha subunit of pyruvate dehydrogenase (E1 alpha)
YFL047W RGD2 0.44 1.0 specific GTPase activating protein (RhoGAP)
YLR215C CDC123 0.44 0.8 Product of gene unknown
YGR187C HGH1 0.44 1.3 HMG1/2 homolog
YPR190C RPC82 0.44 1.1 82-kDa subunit of RNA polymerase III (C)
YPL050C MNN9 0.44 1.2 Protein required for complex glycosylation
YHR088W RPF1 0.44 1.1 protein that localizes to the nucleolus
YKL199C YKT9 0.44 1.1 Protein of unknown function
YMR220W ERG8 0.44 1.0 Involved in isoprene and ergosterol biosynthesis pathways
YOL054W PSH1 0.44 1.4 Pob3/Spt16 Histone associated
YNL113W RPC19 0.44 1.4 subunit common to RNA polymerases I (A) and III (C)
YML104C MDM1 0.44 1.2 Required for nuclear and mitochondrial transmission to daughter buds.
YKL196C YKT6 0.44 1.0 "Synaptobrevin (v-SNARE) homolog with similarity to Sec22p, Snc1p, and Snc2p, essential for endoplasmic reticulum-Golgi transport"
YPR071W 0.44 1.9
YER115C SPR6 0.44 1.1 sporulation-specific protein
YPL027W SMA1 0.44 2.3 Spore Membrane Assembly
YLR455W 0.44 5.1 Z S C
YHR134W WSS1 0.44 1.1 weak suppressor of smt3
YGL054C ERV14 0.44 1.1 ER-derived vesicles
YNL249C MPA43 0.44 1.2 Overexpression leads to increased levels of the lyase PDC1
YBR006W UGA2 0.44 1.8 involved in utilization of GABA as a nitrogen source
YGL115W SNF4 0.44 0.8 "involved in release from glucose repression, invertase expression, and sporulation"
YJR060W CBF1 0.44 1.4 "centromere binding factor; binds in vivo to CDE I sites in centromeres (and some promoters), and induces DNA bending, required for mitotic segregation and normal growth rate"
YPL186C UIP4 0.44 3.3 C Ulp1 Interacting Protein 4
YDL114W 0.44 2.6
YDL097C RPN6 0.44 1.5 "Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit S9/p44.5."
YEL052W AFG1 0.44 1.1 ATPase family gene
YMR146C TIF34 0.44 1.1 p39 subunit of translation initiation factor eIF3
YCL020W 0.44 0.9
YGL033W HOP2 0.44 2.8 HOmologous Pairing
YER034W 0.44 1.6
YHR079C-A SAE3 0.44 1.1 Involved in meiotic recombination and chromosome metabolism
YNL098C RAS2 0.44 0.8 "Ras proto-oncogene homolog. Ras2 is involved in growth on non-fermentable carbon sources, the starvation response, sporulation, pseudohyphal growth and aging."
YPR026W ATH1 0.44 1.7 "Null mutant is viable; increased tolerance to dehydration, freezing, and toxic levels of ethanol
hydrolyzes trehalose"
YDR450W RPS18A 0.44 2.0 Homology to rat S18 and E. coli S13
YDL212W SHR3 0.44 1.2 Protein required for appearance of amino acid permeases on the cell surface
YOR275C RIM20 0.43 1.0 Regulator of IME2
YJR010W MET3 0.43 5.7 Z S one of three genes essential for the assimilatory reduction of sulfate to sulfide (with sulfite as an intermediate product)
YOR380W RDR1 0.43 1.1 Repressor of drug resistance
YEL056W HAT2 0.43 0.8 "subunit of histone acetyltransferase; may regulate activity of Hat1p, the catalytic subunit of histone acetyltransferase"
YLR061W RPL22A 0.43 2.7 Homology to rat L22
YIL114C POR2 0.43 1.9 S Mitochondrial porin
YPL089C RLM1 0.43 1.2 serum response factor-like protein that may function downstream of MPK1 (SLT2) MAP-kinase pathway
YKL099C UTP11 0.43 1.7 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YGR276C RNH70 0.43 1.9 S "RNase H(70), a 70 kDa ribonuclease H"
YEL051W VMA8 0.43 1.2 vacuolar ATPase V1 domain subunit D
YPR184W GDB1 0.43 3.3 Glycogen debranching enzyme; the enzyme that debranches the glycogen having a glucanotranferase + 1-6amyloglucosidase activity
YKL068W NUP100 0.43 1.1 C Participates in nucleocytoplasmic transport; member of GLFG-containing family of nucleoporins
YNL163C RIA1 0.43 1.2 RIbosome Assembly; Elongation Factor Like
YLR456W 0.43 1.3
YPL258C THI21 0.43 3.2 THI for thiamine metabolism. Transcribed in the presence of low level of thiamine (10-8M) and turned off in the presence of high level (10-6M) of thiamine. Under the positive control of THI2 and THI3.
YER104W RTT105 0.43 1.4 "same phenotype as RTT101, 102, 103, 104"
YPL144W 0.43 1.9
YGR105W VMA21 0.43 1.1 "Protein involved in vacuolar H-ATPase assembly or function. Required for the biogenesis of a functional vacuolar ATPase (V-ATPase), but not part of the final enzyme complex."
YPL271W ATP15 0.43 1.7 nuclear gene for ATP synthase epsilon subunit
YHR201C PPX1 0.43 1.0 Cytosolic exopolyphosphatase
YOR059C 0.43 1.4
YDL144C 0.43 1.8
YPL246C 0.43 1.3
YMR211W DML1 0.43 1.0 Drosophila melanogaster Misato-like
YEL018W EAF5 0.43 1.2 C Esa1p-Associated Factor-5
YIL026C IRR1 0.43 4.1 S C Irregular; involved in sister chromatid cohesion
YOL016C CMK2 0.43 2.8 S Calmodulin-dependent protein kinase
YGR267C FOL2 0.43 1.2 First enzyme in biosynthetic pathway for folic acid and tetrahydrobioptern
YBL107C 0.43 1.8
YKL084W 0.43 1.6
YDL141W BPL1 0.43 1.7 Biotin:apoprotein ligase
YGR040W KSS1 0.43 0.8 Recovery from alpha factor arrest
YOR142W LSC1 0.43 1.3 "alpha subunit of succinyl-CoA ligase (synthetase; ATP-forming), a mitochondrial enzyme of the TCA cycle"
YFL039C ACT1 0.43 1.8 "Involved in cell polarization, endocytosis and other cytoskeletal functions"
YPL138C SPP1 0.43 1.2 likely involved in chromatin remodeling
member of Set1p complex
YFR053C HXK1 0.43 3.0 Glucose phosphorylation
YNL055C POR1 0.43 1.5 "Outer mitochondrial membrane porin (voltage-dependent anion channel, or VDAC)"
YHR110W ERP5 0.43 5.7 Z S C Emp24p/Erv25p related protein 5
YBR254C TRS20 0.43 1.9 Trapp subunit of 20 kDa
YMR246W FAA4 0.43 2.8 S "acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatty acid activator 2), activates imported fatty acids and provides substrates for N-myristoylation"
YPL007C TFC8 0.43 2.2 Transcription factor for RNA polymerase III
YML037C 0.43 0.9
YMR038C LYS7 0.43 1.1 "Involved in lysine biosynthesis, oxidative stress protection"
YJL031C BET4 0.43 1.8 catalyzes prenylation of Ypt1p (as a subunit of PGGTase-II)
YGR145W ENP2 0.43 1.6 Essential Nucleolar Protein 2
YJR131W MNS1 0.43 1.5 specific alpha-mannosidase
YDR539W 0.43 1.4
YDL084W SUB2 0.43 1.6 Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1
YAR015W ADE1 0.43 1.9 phosphoribosyl amino imidazolesuccinocarbozamide synthetase
YDR164C SEC1 0.43 1.4 Hydrophilic protein involved at the late stage of secretion
YNL029C KTR5 0.43 1.0 Putative mannosyltransferase of the KRE2 family
YDR374C 0.43 1.7
YMR177W MMT1 0.43 1.7 Protein involved in mitochondrial iron accumulation
YHR113W 0.43 3.0 S C
YKL060C FBA1 0.43 1.6 aldolase
YJL059W YHC3 0.43 1.6 Homolog of human CLN3
YBR176W ECM31 0.43 1.4 ExtraCellular Mutant
YDL057W 0.43 1.4
YOL165C AAD15 0.43 1.3 high degree of similarity with the AAD of P. chrysosporium
YBR280C 0.43 1.6
YJL138C TIF2 0.43 0.8 translation initiation factor eIF4A
YKR059W TIF1 0.43 1.7 translation initiation factor eIF4A
YNL155W 0.43 1.6
YJL061W NUP82 0.43 1.4 Interacts with nuclear pore complex and participates in nucleocytoplasmic transport; required for poly(A)+ RNA export
YOL068C HST1 0.43 1.1 Homolog of SIR2
YPL199C 0.43 1.2
YDR298C ATP5 0.43 1.8 Subunit 5 of the mitochondrial ATP synthase complex; homologous to bovine OSCP and E. coli delta.
YDR288W 0.43 1.2
YMR168C CEP3 0.43 1.1 "Cbf3 kinetochore complex binds CDE III centromere element; Cep3p contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain and a putative coiled coil dimerization domain"
YMR218C TRS130 0.43 1.5 targeting complex (TRAPP) component involved in ER to Golgi membrane traffic; 130 kD subunit
YNR001C CIT1 0.43 1.6 C citrate synthase. Nuclear encoded mitochondrial protein.
YGR057C LST7 0.43 0.8 Required for amino acid permease transport from the Golgi to the cell surface
YBL068W PRS4 0.43 1.1 ribose-phosphate pyrophosphokinase 4
YPL113C 0.43 0.8
YMR023C MSS1 0.43 1.3 May play a part in mitochondrial translation
YAR019C CDC15 0.43 1.3 "Promotes the exit from mitosis by directly switching on the kinase activity of Dbf2. Required for mitosis and sporulation, cell division cycle blocked at 36 C."
YOR133W EFT1 0.43 1.1 translation elongation factor 2 (EF-2)
YDR385W EFT2 0.43 1.0 translation elongation factor 2 (EF-2)
YLR348C DIC1 0.43 1.8 mitochondrial dicarboxylate transport protein
YER159C BUR6 0.43 1.6 Homolog of DRAP1 (NC2alpha)
YGR153W 0.43 2.1 S
YOR350C MNE1 0.43 1.0 similar to Lucilia illustris mitochondria cytochrome oxidase
YGL030W RPL30 0.43 1.5 Homology to rat and mouse L30
YPL204W HRR25 0.43 1.1 "Similar to YCK1 and YCK2, two other casein kinase I isoforms; found primarily in nucleus; may be involved in DNA-damage repair"
YNL252C MRPL17 0.43 1.2 mitochondrial ribosomal protein of the large subunit
YIL113W SDP1 0.43 1.3 Hypothetical ORF
YBR072W HSP26 0.43 3.1 heat shock protein 26
YHR003C 0.43 1.6
YMR085W 0.43 1.4
YHR026W PPA1 0.43 1.1 vacuolar ATPase V0 domain subunit c''
YHR216W IMD2 0.43 0.9 IMP Dehydrogenase
YKL170W MRPL38 0.43 2.5 mitochondrial ribosomal protein L14
YGR163W GTR2 0.43 0.9 "(putative) small GTPase, similar to Gtr1"
YJR025C BNA1 0.43 2.4 biosynthesis of nicotinic acid
YBL058W SHP1 0.43 1.3 isolated as a suppressor of the lethality caused by overexpression of the phosphoprotein phosphatase 1 catalytic subuniut encoded by GLC7
YKR075C 0.43 2.3
YPR037C ERV2 0.43 1.4 "Essential for Respiration and Vegetative growth 2. Protein forms dimers in vivo/vitro, contains a conserved YPCXXC motif at carboxyl-terminal, binds FAD as cofactor, and catalyzes formation of disulfide bonds in protein substrates."
YJL038C 0.42 2.5
YMR178W 0.42 1.0
YFL036W RPO41 0.42 1.7 mitohcondrial RNA polymerase
YOR045W TOM6 0.42 1.5 involved in supporting the cooperativity between receptors and the general insertion pore and facilitating the release of preproteins from import components
YMR120C ADE17 0.42 1.3 AICAR transformylase/IMP cyclohydrolase
YFR049W YMR31 0.42 1.7 mitochondrial ribosomal protein (precursor)
YNL067W RPL9B 0.42 1.5 Homology to rat L9
YLR058C SHM2 0.42 2.6 S serine hydroxymethyltransferase
YOR226C ISU2 0.42 0.9 Iron-sulfur cluster nifU-like protein
YMR264W CUE1 0.42 0.9 Cue1p assembles with Ubc7p. Cue1p recruits Ubc7p to the cytosolic surface of the endoplasmic reticulum. Assembly with Cue1p is a prerequisite for the function of Ubc7p
YLR017W MEU1 0.42 0.9 Protein that regulates ADH2 gene expression
YER035W EDC2 0.42 1.0 Enhancer of mRNA Decapping
YKL151C 0.42 2.5 S
YGL108C 0.42 1.2
YKR014C YPT52 0.42 1.0 rab5-like GTPase involved in vacuolar protein sorting and endocytosis
YBR143C SUP45 0.42 1.2 Recessive omnipotent suppressor. The wild-type gene functions in termination of translation.
YLR345W 0.42 2.0
YLR044C PDC1 0.42 1.8 pyruvate decarboxylase
YMR299C 0.42 2.2
YGR026W 0.42 1.4
YML060W OGG1 0.42 4.4 Z S C "Excises 7,8-dihydro-8-oxoguanine (8-OxoG) when 8-OxoG is oppposite cytosine or thymine (but not adenine)"
YLR223C IFH1 0.42 2.0 Interacts with fork head protein. Protein controlling pre-rRNA processing machinery in conjunction with Fhl1p
YOR097C 0.42 1.9
YDR392W SPT3 0.42 1.4 Transcription factor
YGR252W GCN5 0.42 2.0 functions in the Ada and SAGA (Spt/Ada) complexes to acetylate nucleosomal histones
YGR240C PFK1 0.42 2.4 S phosphofructokinase alpha subunit
YBR056W 0.42 2.4
YEL012W UBC8 0.42 1.2 Ubiquitin-conjugating enzyme that is able to ubiquitinate histones in vitro
YDR183W PLP1 0.42 1.6 Phosducin-Like Protein
YCR020C PET18 0.42 1.3 Transcription regulator
YLR408C 0.42 0.9
YPL131W RPL5 0.42 1.4 Homology to rat ribosomal protein L5; required for assembly of stable 60S ribosomal subunits
YNL261W ORC5 0.42 1.4 May be subunit of origin recognition complex (ORC) that mediates the ATP-dependent binding to origins; the ORC binds to origins of replication and thereby directs DNA replication and is also involved in transcriptional silencing
YCR047C BUD23 0.42 1.5
YPR163C TIF3 0.42 1.1 Suppressor of translation mutants
YFL025C BST1 0.42 1.1 Negatively regulates COPII vesicle formation
YER113C 0.42 1.0
YGL017W ATE1 0.42 1.0 arginyl-tRNA-protein transferase
YOR283W 0.42 1.7 S
YOR269W PAC1 0.42 1.4 Required for viability in the absence of the kinesin-related Cin8p mitotic motor.
YBR205W KTR3 0.42 0.9 "Putative alpha-1,2-mannosyltransferase"
YMR015C ERG5 0.42 2.8 S cytochrome P450 involved in C-22 denaturation of the ergosterol side-chain
YBR101C 0.42 1.1
YMR241W YHM2 0.42 1.4 Yeast suppressor gene of HM mutant (abf2)
YMR298W 0.42 1.9
YLR153C ACS2 0.42 1.4 one of 2 acetyl-coA synthetases in yeast
YER072W VTC1 0.42 1.2 Null mutant identified in different genetic screens both by its ability to reverse the Cdc42p suppression of a cdc24-4ts mutant and its ability to suppress the vacuolar ATPase null phenotype
YKL097C 0.42 1.6
YGR247W CPD1 0.42 1.2 "2',3'-cyclic nucleotide 3'-phosphodiesterase, similar to cyclic phosphodiesterases from Arapidopsis and wheat"
YGR046W 0.42 1.0
YPL211W NIP7 0.42 1.1 Nip7p is required for 60S ribosome subunit biogenesis
YCR026C 0.42 1.3
YLR285W 0.42 1.4
YKL103C LAP4 0.42 3.3 S vacuolar aminopeptidase ysc1
YBR003W COQ1 0.42 0.9 hexaprenyl diphosphate synthesis
YCR018C SRD1 0.42 2.7 S involved in the processing of pre-rRNA to mature rRNA
YLR393W ATP10 0.42 0.8 essential for assembly of a functional mitochondrial ATPase complex
YCR046C IMG1 0.42 1.9 Required for respiration and maintenance of mitochondrial genome
YOR117W RPT5 0.42 1.2 Probable 26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases
YMR255W GFD1 0.42 1.0 Great for FULL DEAD box protein activity
YGL256W ADH4 0.42 1.0 Alcohol dehydrogenase type IV
YKL037W 0.42 1.6
YAL038W CDC19 0.42 2.1 Required for START A in the cell cycle and sporulation
YOL069W NUF2 0.42 4.5 Z S C Protein associated with spindle pole body and critical for nuclear division
YLL013C PUF3 0.42 0.9 "member of the PUF protein family, which is named for the founding members, PUmilio and Fbf"
YNR036C 0.42 1.2
YOL052C SPE2 0.42 1.3 S-adenosylmethionine decarboxylase
YML038C YMD8 0.42 1.8 similar to vanadate resistance protein Gog5
YLR424W 0.42 2.4
YDR003W 0.42 1.2
YLR133W CKI1 0.42 1.8 choline kinase
YOL055C THI20 0.42 0.9 THI for thiamine metabolism. Transcribed in the presence of low level of thiamine (10-8M) and turned off in the presence of high level (10-6M) of thiamine. Under the positive control of THI2 and THI3.
YOR361C PRT1 0.42 0.8 translation initiation factor eIF3 subunit
YGL211W 0.42 1.0
YGL206C CHC1 0.42 1.4 vesicle coat protein
YOL045W PSK2 0.42 1.2 PAS domain-containing Serine/threonine Kinase
YJL049W 0.42 1.4
YIL121W 0.42 2.3 S
YDL161W ENT1 0.42 1.0 epsin N-terminal homology-containing protein
YHR112C 0.41 1.1
YBR245C ISW1 0.41 1.2 has strong homology to Drosophila ISWI
YDR346C SGI1 0.41 2.3 S mutant Suppressor of Growth Inhibition by phosphorylated sphingoid bases
YLR028C ADE16 0.41 1.7 AICAR transformylase/IMP cyclohydrolase
YPL043W NOP4 0.41 1.5 RNA recognition motif-containing protein
YPL148C PPT2 0.41 2.2 Phosphopantetheine:protein transferase (PPTase) that activates the low molecular weight acyl carrier protein (ACP) of mitochondrial type II fatty acid synthase (FAS).
YBR041W FAT1 0.41 1.4 Putative membrane-bound long-chain fatty acid transport protein homologous to mouse fatty acid transport protein
YDR110W FOB1 0.41 0.9 The gene product is essential for both DNA replication fork blocking and recombinational hotspot activities.
YDR291W 0.41 0.8
YJL035C TAD2 0.41 2.2 tRNA-specific adenosine-34 deaminase subunit Tad2p
YIL129C TAO3 0.41 6.0 Z S Identified in a hunt for mutants that activate OCH1 transcription
YGR193C PDX1 0.41 1.2 Plays a structural role in pyruvate dehydrogenase complex
YJR104C SOD1 0.41 1.2 "Cu, Zn superoxide dismutase"
YDR280W RRP45 0.41 1.3 Ribosomal RNA Processing
YAL002W VPS8 0.41 0.8 involved in vacuolar protein sorting; required for localization and trafficking of the CPY sorting receptor
YMR262W 0.41 2.1
YDR083W RRP8 0.41 1.4
YBR121C GRS1 0.41 0.9 Glycyl-tRNA synthase
YNL139C RLR1 0.41 0.9 Required for LacZ RNA expression from certain plasmids; suppressor of the Transcriptional (T) defect of Hpr1 (H) by Overexpression (O); plays a role in transcription elongation by RNA polymerase II
YBR261C 0.41 1.7
YBR055C PRP6 0.41 0.9 RNA splicing factor
YGR055W MUP1 0.41 3.8 S high affinity methionine permease
YGL196W 0.41 1.2
YJR129C 0.41 1.4
YGL097W SRM1 0.41 1.9 Z Gdp/GTP exchange factor for Gsp1p/Gsp2p
YDR260C SWM1 0.41 1.6 Spore Wall Maturation 1
YOR136W IDH2 0.41 2.1 NAD+-dependent isocitrate dehydrogenase
YKR023W 0.41 1.2
YLR206W ENT2 0.41 1.7 epsin N-terminal homology-containing protein
YMR182C RGM1 0.41 0.9 Putative transcriptional repressor with proline-rich zinc fingers
YMR002W 0.41 2.0 S
YKL193C SDS22 0.41 1.0 Interacts with and may be a positive regulator of GLC7 which encodes type1 protein phosphatase
YPL233W NSL1 0.41 1.4 Nnf1 Synthetic Lethal 1
YLR304C ACO1 0.41 1.7 "Aconitase, mitochondrial"
YOL145C CTR9 0.41 2.0 CTR9 is required for normal CLN1 and CLN2 G1 cyclin expression
YBR112C CYC8 0.41 1.4 General repressor of transcription (with Tup1p); mediates glucose repression
YDR051C 0.41 1.4
YPL022W RAD1 0.41 0.8 UV endonuclease
YPR034W ARP7 0.41 2.3 S involved in transcriptional regulation
YIL159W BNR1 0.41 2.0 C "Bni1p-related protein, helps regulate reorganization of the actin cytoskeleton, potential target of Rho4p"
YNL001W DOM34 0.41 1.5 an ORF of unknown function located in a centromeric region duplicated between chromosomes III and XIV (DOM34 homologue on chromosome III is a pseudogene)
YGR165W 0.41 1.3
YNL073W MSK1 0.41 2.2 C mitochondrial lysine-tRNA synthetase
YGR198W 0.41 1.1
YDR268W MSW1 0.41 0.9 mitochondrial tryptophanyl-tRNA synthetase
YFL058W THI5 0.41 1.6 proposed biosynthetic enzyme involved in pyrimidine biosynthesis pathway above the hydroxymethyl-pyrimidine precursor leading to the thiaminemoiety
YOR245C DGA1 0.41 1.0 DiacylGlycerol Acyltransferase
YGR082W TOM20 0.41 0.8 Translocase of Outer Mitochondrial membrane
YPR036W VMA13 0.41 1.1 vacuolar ATPase V1 domain subunit H (54 kDa)
YAR020C PAU7 0.41 1.1 "similar to Pau3, member of Pau1 family"
YGL062W PYC1 0.41 3.3 converts pyruvate to oxaloacetate
YML002W 0.41 1.1
YBR258C SHG1 0.41 0.8
YMR226C 0.41 1.3
YLR297W 0.41 4.3 S C
YJL102W MEF2 0.41 1.4 mitochondrial elongation factor G-like protein
YJR139C HOM6 0.41 1.1 catalyzes third step in common pathway for methionine and threonine biosynthesis
YFL007W BLM3 0.41 1.2 bleomycin resistance
YOL028C YAP7 0.41 1.4 basic leucine zipper (bZIP) transcription factor
YEL027W CUP5 0.41 2.0 vacuolar ATPase V0 domain subunit c (17 kDa)
YCR042C TAF2 0.41 4.9 S C TATA binding protein-associated factor (TAF)
YMR217W GUA1 0.41 0.9 GMP synthase
YGL067W NPY1 0.41 1.5 hydrolyzes the pyrophosphate linkage in NADH and related nucleotides
YMR174C PAI3 0.41 2.2 Cytoplasmic inhibitor of proteinase Pep4p
YFL008W SMC1 0.41 3.3 S C coiled-coil protein involved in chromosome structure or segregation
YDR429C TIF35 0.41 1.5 Translation initiation factor 3 p33 subunit
YOL031C 0.41 1.1
YPR101W SNT309 0.41 2.4 Synergistic to prp19 (NineTeen) mutation. Essential for mRNA splicing.
YLR093C NYV1 0.41 1.2 Synaptobrevin (v-SNARE) homolog involved in vacuolar vesicle fusion
YBR115C LYS2 0.41 1.3 "A key step in fungal biosynthesis of lysine, enzymatic reduction of alpha-aminoadipate at C6 to the semialdehyde, requires two gene products in Saccharomyces cerevisiae, Lys2 and Lys5."
YLR377C FBP1 0.41 1.3 "fructose-1,6-bisphosphatase"
YOL162W 0.41 1.7
YDR373W FRQ1 0.41 1.5 Product of gene unknown
YKL057C NUP120 0.41 1.0 Nucleoporin
YBR165W UBS1 0.41 1.6 General positive regulator of CDC34; Suppress some cdc34 mutations when over-expressed
YMR193W MRPL24 0.41 2.8 Mitochondrial ribosomal protein MRPL24 (YmL24)
YNL077W 0.41 1.7
YLL063C AYT1 0.41 0.9 Transacetylase
YOL081W IRA2 0.41 1.8 Negatively regulates cAPK by antagonizing CDC25
YBR091C MRS5 0.41 0.8 "Involved in mitochondrial biogenesis, may share a common function with Mrs11p"
YDR281C PHM6 0.41 2.9 Phosphate metabolism; transcription is regulated by PHO system
YMR302C PRP12 0.41 1.0 Integral membrane mitochondrial protein
YHR136C SPL2 0.41 1.1 Suppressor of plc1-delta. Isolated as a dosage suppressor of the temperature-sensitive phenotype of a plc1 null mutant. Also suppresses the hyperosmotic-sensitive phenotype of the plc1 null mutant.
YBR170C NPL4 0.41 1.2 Nuclear pore or nuclear pore-associated protein required for nuclear membrane integrity and nuclear transport
YJL088W ARG3 0.41 1.6 Sixth step in arginine biosynthesis
YJR078W BNA2 0.41 2.3 Biosynthesis of Nicotinic Acid
YJL137C GLG2 0.40 3.4 S C self-glucosylating initiator of glycogen synthesis; similar to mammalian glycogenin
YML106W URA5 0.40 2.3 Fifth step in pyrimidine biosynthesis pathway
YLR148W PEP3 0.40 1.3 vacuolar membrane protein
YJL162C 0.40 1.1
YNR034W SOL1 0.40 0.8 Multicopy Suppressor Of los1
YBR133C HSL7 0.40 2.9 S Histone Synthetic Lethal
Negative regulator of Swe1 kinase
YMR300C ADE4 0.40 1.8 phosphoribosylpyrophosphate amidotransferase
YER086W ILV1 0.40 1.1 threonine deaminase
YDL167C NRP1 0.40 1.4 asparagine-rich protein
YJL217W 0.40 3.2 S
YOR008C-A 0.40 0.1
YKL075C 0.40 1.4
YDR275W 0.40 1.2
YKL127W PGM1 0.40 3.3 S C "phosphoglucomutase, minor isoform"
YBR230C 0.40 2.9
YIL116W HIS5 0.40 1.7 responsive to control of general amino acid biosynthesis
YMR131C RRB1 0.40 1.2 RiboSome Assembly 2
YOL071W EMI5 0.40 1.6 Early Meiotic Induction
YGL059W 0.40 2.0 C
YLR303W MET17 0.40 4.3 S O-Acetylhomoserine-O-Acetylserine Sulfhydralase
YDR301W CFT1 0.40 1.0 "Functions in cleavage of 3'-ends of pre-mRNAs, prior to polyadenylation; 23.5% identical to the 160-kDa subunit of mammalian cleavage and polyadenylation specificity factor (CPSF-160)"
YJR084W CSN12 0.40 1.7 COP9 signalosome (CSN)
YBR057C MUM2 0.40 1.2 Muddled Meiosis
YLR245C CDD1 0.40 1.4 Involved in cytidine and deoxycytidine metabolism
YGL174W BUD13 0.40 1.4
YBR283C SSH1 0.40 1.5 SEC61 homolog involved in co-translational pathway of protein transport
YGR184C UBR1 0.40 1.0 Ubiquitin-protein ligase
YGR169C PUS6 0.40 1.3 RNA:Psi-synthase
YPL196W OXR1 0.40 1.7 OXidation Resistance
YFL020C PAU5 0.40 1.3 member of the seripauperin protein/gene family (see Gene_class PAU)
YDL168W SFA1 0.40 1.2 Long-chain alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)
YPR155C NCA2 0.40 1.7 S Regulates proper expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase
YOR005C DNL4 0.40 1.2 DNA ligase IV homolog
YGR250C 0.40 0.8
YGR172C YIP1 0.40 1.3 Golgi integral membrane protein; binds to the transport GTPases Ypt1p and Ypt31p
YPR074C TKL1 0.40 1.4 Transketolase 1
YDR232W HEM1 0.40 1.2 First enzyme in heme biosynthetic pathway
YOR376W 0.40 2.5
YHR047C AAP1' 0.40 1.1 arginine/alanine aminopeptidase
YPR058W YMC1 0.40 1.2 putative mitochondrial carrier protein
YBL055C 0.40 1.3
YOL119C MCH4 0.40 2.9 S monocarboxylate permease homologue
YIR030C DCG1 0.40 1.0 Product of gene unknown
YDL043C PRP11 0.40 1.4 snRNA-associated protein
YJL039C NUP192 0.40 1.1 large yeast nucleoporin
YPL122C TFB2 0.40 1.3 Transcription/repair factor TFIIH subunit
YJR039W 0.40 0.9
YPL183C 0.40 1.4
YML077W BET5 0.40 1.0 Bet5p/18kD component of TRAPP
YJL123C 0.40 1.2
YGR136W LSB1 0.40 1.4 LAs17 Binding protein
YNL084C END3 0.40 1.1 Required for endocytosis and organization of the cytoskeleton
YOL058W ARG1 0.40 3.1 S arginosuccinate synthetase
YHR025W THR1 0.40 0.9 homoserine kinase
YGL107C RMD9 0.40 1.0 Required for Meiotic nuclear Division
YLR063W 0.40 1.9
YDR388W RVS167 0.40 1.2 "The BAR adaptor proteins encoded by RVS167 and RVS161 form a complex that regulates actin, endocytosis, and viability following starvation or osmotic stress."
YDL110C 0.40 1.1
YBL086C 0.40 1.5
YPL175W SPT14 0.40 1.5 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
YJR124C 0.40 1.5
YOL153C 0.40 1.9
YPL157W TGS1 0.40 1.5 TrimethylGuanosine Synthase
YHR187W IKI1 0.40 0.9 RNA polymerase II Elongator associated protein
YHL036W MUP3 0.40 1.6 methionine uptake
YPR200C ARR2 0.40 1.6 Required for arsenate but not for arsenite resistance
YOR385W 0.40 2.5
YHR177W 0.40 1.5
YCR107W AAD3 0.40 1.9 high degree of similarity with the AAD of P. chrysosporium
YHR074W QNS1 0.40 1.6 Glutamine-dependent NAD Synthetase
YLR375W STP3 0.40 1.5 Involved in pre-tRNA splicing and in uptake of branched-chain amino acids
YLL061W MMP1 0.40 2.6 S C S-MethylMethionine Permease
YGR234W YHB1 0.40 1.6 S may play a role in the oxidative stress response
YMR048W CSM3 0.40 3.7 S C Chromosome segregation in meiosis
YNL328C MDJ2 0.40 2.8 S "Protein of the mitochondrial inner membrane with similarity to E. coli DnaJ and other DnaJ-like proteins, function partially overlaps that of Mdj1p"
YNL134C 0.40 3.9 S
YNL181W 0.40 2.5 S
YIL037C PRM2 0.40 3.1 pheromone-regulated membrane protein
YHR133C 0.40 1.4
YIR043C 0.40 1.5
YBR276C PPS1 0.40 1.6 C Protein Phosphatase S phase
YJR053W BFA1 0.40 2.3 Byr four alike
YEL065W SIT1 0.40 4.7 S Siderophore Iron Transport
YBR117C TKL2 0.40 1.4 "transketolase, homologous to tkl1"
YGL250W 0.40 1.3
YMR214W SCJ1 0.40 2.0 dnaJ homolog
YMR138W CIN4 0.40 0.9 Protein involved in chromosome segregation and microtubule function; homologue of human Arl2
YFL045C SEC53 0.40 3.0 involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for protein assembly in endoplasmic reticulum
YLR388W RPS29A 0.39 1.3 Homology to rat S29
YAL053W 0.39 2.1 S
YMR270C RRN9 0.39 1.8 Upstream activation factor subunit
YHR060W VMA22 0.39 0.8 "Required for V-ATPase activity. Required for the biogenesis of a functional vacuolar ATPase (V-ATPase), but not part of the final enzyme complex."
YLR039C RIC1 0.39 1.3 involved in transcription of ribosomal protein genes and ribosomal RNA
YGL142C GPI10 0.39 1.3 "Involved in glycosyl phosphatidyl inositol synthesis; could be the target of the GPI synthesis inhibitor, YW3548; Most likely an alpha 1,2 mannosyltransferase utilized for the addition of the third mannose onto the GPI core structure."
YDR180W SCC2 0.39 1.6 Sister chromatid cohesion protein
YNL213C 0.39 1.2
YBR135W CKS1 0.39 1.5 subunit of the Cdc28 protein kinase
YMR082C 0.39 1.4
YDR517W GRH1 0.39 1.8 Yeast (GR)ASP65 (H)omologue
YLR174W IDP2 0.39 1.5 "concerts isocitrate and NADP+ to 2-oxoglutarate, CO2, and NADPH"
YBL076C ILS1 0.39 1.6 cytoplasmic isoleucyl-tRNA synthetase
YOR369C RPS12 0.39 1.7 Homology to rat S12
YLR384C IKI3 0.39 0.9 RNA polymerase II Elongator subunit
YGL252C RTG2 0.39 0.9 "Protein involved in interorganelle communication between mitochondria, peroxisomes, and nucleus"
YPR170C 0.39 1.3
YPL047W 0.39 1.6
YHR001W-A QCR10 0.39 1.9 8.5 kDa subunit of the ubiqunol-cytochrome c oxidoreductase complex
YOR104W PIN2 0.39 2.6 S [PSI+] induction
YNL217W 0.39 1.8
YHR018C ARG4 0.39 2.8 argininosuccinate lyase
YLR196W PWP1 0.39 1.0 periodic tryptophan protein
Protein with periodic trytophan residues that resembles members of beta-transducin superfamily because of presence of WD-40 repeats
YPL243W SRP68 0.39 1.0 part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
YJR006W HYS2 0.39 3.3 Z S C Putative role in DNA replication
YCR101C 0.39 2.4
YMR258C 0.39 1.7
YDL054C MCH1 0.39 0.8 Monocarboxylate Permease Homologue
YMR108W ILV2 0.39 0.8 acetolactate synthase
YDR175C RSM24 0.39 1.1 mitochondrial ribosome small subunit component
YKR016W 0.39 1.5
YPL092W SSU1 0.39 3.5 putative sulfite pump
YOL161C 0.39 1.3
YBL013W FMT1 0.39 1.4 Formyl-Methionyl-tRNA Transformylase (consistent with name of bacterial homologs)
YLR178C TFS1 0.39 3.4 (putative) lipid binding protein; supressor of a cdc25 mutation
YNL242W APG2 0.39 2.0 Defective in autophagy; required for sporulation
YMR025W CSI1 0.39 0.8 COP9 signalosome interactor
YPL031C PHO85 0.39 1.2 involved in phosphate and glycogen metabolism and cell cycle progression
YAL018C 0.39 1.8
YGR024C 0.39 1.2
YGL089C MF(ALPHA)2 0.39 4.6 S C alpha mating factor
YGL244W RTF1 0.39 1.0 "Directly or indirectly regulates DNA-binding properties of Spt15p, TATA box-binding protein, and relative activities of different TATA elements. Member of RNA polymerase II-associated Paf1 complex."
YLR421C RPN13 0.39 0.8 Proteasome subunit
YPR180W AOS1 0.39 1.4 along with Uba2p forms a heterodimeric activating enzyme for Smt3p
YBL044W 0.39 2.6
YHL021C 0.39 2.3
YDR457W TOM1 0.39 1.3 Temperature dependent Organization in Mitotic nucleus
YIL003W DRE3 0.39 1.2 Protein required for cell viability
YDR460W TFB3 0.39 1.9 Transcription/repair factor TFIIH subunit
YGR148C RPL24B 0.39 2.0 Homology to rat L24
YOR056C NOB1 0.39 1.6 Nin1 (One) Binding protein
YIR027C DAL1 0.39 1.5 allantoinase
YBL078C AUT7 0.39 1.3 "Forms a protein complex with Aut2p to mediate attachment of autophagosomes to microtubules. Defective in maturation of the vacuolar protein, aminopeptidase I"
YGR021W 0.39 0.9
YKL204W EAP1 0.39 1.0 Translation initiation factor eIF-4E associated protein
YLR104W 0.39 1.1
YOR222W ODC2 0.39 1.4
YFL030W 0.39 2.0
YIL098C FMC1 0.39 1.7 Formation of Mitochondrial Complexes
YIL057C 0.39 1.9
YCL038C AUT4 0.39 2.5 S C Autophagy gene essential for breakdown of autophagic vesicles in the vacuole
YPL252C YAH1 0.39 1.4 Yeast Adrenodoxin Homologue 1; This protein is targeted to the mitochondrial matrix as shown by using a specific polyclonal antibody
YOL139C CDC33 0.39 1.2 Required for START A of cell cycle and sporulation
YER015W FAA2 0.39 1.4 "acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatty acid activator 2), activates endogenous but not imported fatty acids and provides substrates for N-myristoylation"
YBR080C SEC18 0.39 1.2 cytoplasmic protein involved in protein transport between ER and Golgi; ATPase
YMR134W 0.39 2.3
YDL143W CCT4 0.39 0.9 cytoplasmic chaperonin subunit required for actin cytoskeleton assembly or function
YBR265W TSC10 0.39 1.5 catalyzes the second step in the synthesis of phytosphingosine
YDR352W 0.39 1.2
YPR017C DSS4 0.39 1.6 dominant suppressor of sec4
YMR056C AAC1 0.39 2.1 "minor species of mitochondrial ADP/ATP translocator, highly homologous to PET9 (AAC2) and AAC3"
YKL149C DBR1 0.39 1.2 RNA lariat debranching enzyme
YNL068C FKH2 0.39 2.4 Z Fork Head homolog two
YOR006C 0.39 1.4
YNR054C 0.39 1.1
YJR125C ENT3 0.39 1.6 epsin N-terminal homology-containing protein
YJR007W SUI2 0.39 1.6 eIF2 is a heterotrimeric GTP-binding protein
SUI3 encodes the beta subunit
GCD11 encodes the gamma subunit
YJL130C URA2 0.39 1.0 First and second steps of pyrimidine biosynthesis
YGR036C CAX4 0.39 1.9 "CAX4p contains 3 short stretches of amino acids that are characteristic for a wide variety of phosphatases, including lipid phosphatases and a protein phosphatase."
YDR318W MCM21 0.39 1.5 Involved in minichromosome maintenance
YGR044C RME1 0.39 6.1 K S C mediates cell type control of sporulation; negatively regulates IME1 and sporulation
YOR129C 0.39 2.6 S
YBL030C PET9 0.39 2.4 S the major mitochondrial ADP/ATP translocator; highly homologous to AAC1 and AAC3
YDR543C 0.39 1.5
YBL106C SRO77 0.39 1.1 Suppressor of defect in the small GTPase Rho3p
YLR249W YEF3 0.39 1.5 "contains two ABC cassettes, and binds and hydrolyses ATP"
YHR170W NMD3 0.39 1.0 putative Upf1p-interacting protein
YJL099W CHS6 0.39 2.7 S C Involved in chitin biosynthesis and/or its regulation
YJR123W RPS5 0.39 1.4 "ribosomal small subunit protein homologous to mammalian S5 (has approx. 70% identity with human, rat and hydrozoan S5). It is the least basic of the non-acidic ribosomal proteins. It is phosphorylated in yeast."
YNL244C SUI1 0.39 1.2 translation initiation factor 3 (eIF3)
YPL255W BBP1 0.39 2.7 S Involved in mitotic cell cycle and meiosis
YMR149W SWP1 0.39 1.5 "oligosaccharyl transferase glycoprotein complex, delta subunit"
YLR320W MMS22 0.39 1.0
YKR020W VPS67 0.39 1.0 whiskey (whi) mutant
YHR165C PRP8 0.38 0.8 protein involved in mRNA splicing; lies at the catalytic center of the spliceosome; makes extensive contacts with the U5 snRNA and with the pre-mRNA
YGL043W DST1 0.38 1.2 Transcription elongation factor S-II
Meiotic DNA recombination factor
YDR142C PEX7 0.38 1.0 May serve as intraperoxisomal receptor for type 2 peroxisomal proteins (such as thiolase)
YBR267W 0.38 1.5
YLR227C ADY4 0.38 0.8 Accumulation of dyads
YPL212C PUS1 0.38 1.1 Involved in tRNA biogenesis
YOR065W CYT1 0.38 2.2 C Cytochrome c1
YOR239W ABP140 0.38 1.0 actin filament binding protein
YGR019W UGA1 0.38 2.1 gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase)
YGR231C PHB2 0.38 2.0 Possible role in aging
YGR144W THI4 0.38 1.9 Protein highly expressed in early stationary phase during growth on molasses
YAL012W CYS3 0.38 1.8 catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine
YBL079W NUP170 0.38 1.5 Component of yeast nuclear pore complex; may play a role in localizing specific nucleoporins to nuclear pore complex; High identity with Sc nucleoporin NUP157 & to mammalian nucleoporin Nup155p. Complemented with Nup155p
YPL226W NEW1 0.38 1.3 "This gene encodes a protein with an Q/N-rich amino terminal domain that acts as a prion, termed [NU]+."
YDR002W YRB1 0.38 1.5 Yeast Ran Binder #1; suppressor of FUS1; homolog of mouse HTF9a and human RanBP1
YMR229C RRP5 0.38 0.9 Part of small ribosomal subunit (SSU) processosome (contains U3 snoRNA). Rrp5p is the only ribosomal RNA processing trans-acting factor that is required for the synthesis of both 18S and 5.8S rRNAs.
YPR108W RPN7 0.38 1.1 "Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit S10/p44"
YNL014W HEF3 0.38 1.2 Translational elongation factor EF-3B
YNL075W IMP4 0.38 1.4 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); Interacts With Mpp10. Imp4p is a specific component of the U3 snoRNP and is required for pre-18S rRNA processing.
YJL207C 0.38 1.7
YMR253C 0.38 2.8 S
YNL025C SSN8 0.38 0.8 "Component of RNA polymerase II holoenzyme, involved in RNA pol II carboxy-terminal domain phosphorylation. Activity of the kinase (SSN3)/cyclin (SSN8) pair required, along with SSN6 & TUP1, for transcriptional repression of a-specific genes"
YMR166C 0.38 2.4
YJR116W 0.38 1.8
YJL176C SWI3 0.38 2.1 transcription factor
YHL049C 0.38 5.4 Z S
YOR026W BUB3 0.38 1.8 C Protein required for cell cycle arrest in response to loss of microtubule function
YCR003W MRPL32 0.38 1.7 Mitochondrial ribosomal protein MRPL32 (YmL32)
YNL039W BDP1 0.38 1.4 RNA polymerase III Transcription factor TFIIIB (90 kDa subunit; also called TFIIIB90 or B'' or B''90 component)
YOR228C 0.38 1.9
YIL175W 0.38 1.9
YMR278W 0.38 1.9 S
YLR438W CAR2 0.38 3.2 S ornithine aminotransferase
YHR129C ARP1 0.38 1.4 actin-related protein of the dynactin complex
YBR100W 0.38 1.2
YHR172W SPC97 0.38 2.4 S C Spindle Pole Body component with an molecular weight of 97 kDa
YOR176W HEM15 0.38 3.5 S "Performs last step in heme biosynthesis pathway, inserting ferrous iron into protoporphyrin IX"
YKR103W 0.38 2.0 S
YLR241W 0.38 1.4
YPR173C VPS4 0.38 1.9 Defective in vacuolar protein sorting; homologous to mouse SKD1 and to human hVPS4
YBR085W AAC3 0.38 1.5 highly homologous to PET9 (AAC2) and AAC1; expression occurs only under anaerobic conditions
YBR246W 0.38 1.0
YGL157W 0.38 1.9
YER078C 0.38 1.5
YDR237W MRPL7 0.38 1.1 Mitochondrial ribosomal protein MRPL7 (YmL7)
YGR003W 0.38 1.2
YNL024C 0.38 1.3
YCR079W 0.38 0.9
YGL121C GPG1 0.38 2.7 "G protein gamma. Gpg1 interacts with Gpa2, Gpb1 (YOR371c), and Gpb2 (YAL056w) in yeast two hybrid assays. The interaction between Gpa2 and Gpg1 is indirect and requires Gpb1 OR Gpb2."
YGR208W SER2 0.38 1.0 phosphoserine phosphatase
YDL076C RXT3 0.38 1.2 Hypothetical ORF
YPL266W DIM1 0.38 1.9 "Dimethyladenosine transferase, (rRNA(adenine-N6,N6-)-dimethyltransferase),reponsible for m6[2]Am6[2]A dimethylation in 3'-terminal loop of 18S rRNA"
YGL125W MET13 0.38 2.2 S putative methylenetetrahydrofolate reductase (mthfr)
YLR253W 0.38 1.2
YER014W HEM14 0.38 2.0 converts protoporphyrinogen IX to protoporphyrin IX (in synthesis of heme)
YLR370C ARC18 0.38 1.4 Arp2/3 complex subunit
YCL028W RNQ1 0.38 1.1 Rich in asparagine (N) and glutamine (Q)
YPR189W SKI3 0.38 0.9 "dsRNA virus protection family member, contains 8 copies of the tetratricopeptide (TPR) domain"
YML094W GIM5 0.38 1.3 "Prefoldin subunit 5; putative homolog of subunit 5 of bovine prefoldin, a chaperone comprised of six subunits"
YPR055W SEC8 0.38 1.6 "121 kDa component of the Exocyst complex, which is required for exocytosis, and which also contains the gene products encoded by SEC3, SEC5, SEC6, SEC10, SEC15, and EXO70"
YMR323W 0.38 1.6
YLR387C 0.38 1.0
YOR347C PYK2 0.38 2.8 "Pyruvate kinase, glucose-repressed isoform"
YLR380W CSR1 0.38 2.7 Z S "chs5 spa2 rescue; isolated as a multicopy suppressor of the lethality of chs5 spa2 double mutant at 37 degrees. Also Sec14p homolog, putative phosphatidylinositol transfer protein."
YER091C MET6 0.38 3.6 S cobalamin-independent methionine synthase
YDL244W THI13 0.38 1.0 Product of gene unknown
YEL071W DLD3 0.38 2.5 D-lactate dehydrogenase
YAL044C GCV3 0.38 1.7 H-protein subunit of the glycine cleavage system
YDL066W IDP1 0.38 0.8 Mitochondrial form of NADP-specific isocitrate dehydrogenase
YNL050C 0.38 1.1
YFR026C 0.38 3.6 C
YDR078C SHU2 0.38 1.1 Suppressor of hydroxy-urea sensitivity
YGR086C 0.38 4.1 S
YER044C ERG28 0.38 1.6 Transmembrane domain containing protein which may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or to tether these enzymes to the ER
YFL044C 0.38 2.9 S
YLL041C SDH2 0.38 2.2 "Yeast succinate dehydrogenase (SDH) is a tetramer of non-equivalent subunits--Sdh1p, Sdh2p, Sdh3p, Sdh4p--that couples the oxidation of succinate to the transfer of electrons to ubiquinone."
YPL193W RSA1 0.38 1.0 RiboSome Assembly
YPR046W MCM16 0.38 1.1 Involved in a nonessential role that governs the kinetochore-microtubule mediated process of chromosome segregation
YDR082W STN1 0.38 1.1 "involved in telomere length regulation, function in telomere metabolism during late S phase"
YCR036W RBK1 0.38 1.7 ribokinase
YHR039C-A VMA10 0.38 0.8 vacuolar H-ATPase 13 kDa subunit of VO membrane sector
YPL121C MEI5 0.38 1.9 Meiotic protein required for synapsis and meiotic recombination
YPL107W 0.38 1.3
YIL006W 0.38 1.0
YBR166C TYR1 0.38 2.0 Step of tyrosine biosynthesis pathway
YOR296W 0.38 0.8
YDL183C 0.38 0.9
YDL080C THI3 0.38 1.3 Positive regulatory factor with thiamin pyrophosphate-binding motif for thiamin metabolism
YDR297W SUR2 0.38 4.0 Z S C Suppressor of rvs161 and rvs167 mutations
YJR156C THI11 0.37 1.5 "thiamine regulated gene, homologous to S. pombe NMT1A. Proposed biosynthetic enzyme involved in pyrimidine biosynth. pathway above the hydroxymethyl-pyrimidine precursor leading to the thiamine moiety. Three copies THI5, THI11 & THI12"
YLR071C RGR1 0.37 1.0 "affects chromatin structure, transcriptional regulation of diverse genes and sporulation, required for glucose repression, HO repression, RME1 repression and sporulation"
YBR044C TCM62 0.37 2.3 mitochondrial protein; (putative) chaperone
YHR058C MED6 0.37 1.0 RNA polymerase II transcriptional regulation mediator
YMR107W 0.37 2.1
YBR140C IRA1 0.37 1.3 "Inhibitory regulator of the RAS-cAMP pathway, negatively regulates cAPK by antagonizing CDC25"
YDL153C SAS10 0.37 1.2 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); Something About Silencing 10
YDR470C UGO1 0.37 0.8 outer membrane protein required for for mitochondrial fusion
YGL126W SCS3 0.37 3.0 Required for inositol prototrophy
YPR018W RLF2 0.37 5.7 Z S C "Chromatin Assembly Complex, subunit 1: largest (p90) subunit of three-subunit protein complex (yeast CAF-I) involved in DNA-replication-linked nucleosome assembly. Homol. to p150 subunit human Chromatin Assembly Factor-I (CAF-I)"
YAL039C CYC3 0.37 2.3 cytochrome c heme lyase (CCHL)
YOR187W TUF1 0.37 1.3 "Translation elongation factor Tu, mitochondrial"
YLR149C 0.37 1.9
YHR030C SLT2 0.37 2.7 S Suppressor of lyt2
YPL139C UME1 0.37 1.6 Negative regulator of meiosis. Unscheduled Meiotic gene Expression.
YLL056C 0.37 1.0
YDR004W RAD57 0.37 1.4 "Required for X-ray damage repair, meiotic recombination, wild-type levels of sporulation and viable spores"
YGR084C MRP13 0.37 2.4 35 kDa mitochondrial ribosomal small subunit protein
YLR315W NKP2 0.37 1.3 Non-essential Kinetochore Protein
YDL103C QRI1 0.37 3.6 Z S C UDP-N-acetylglucosamine pyrophosphorylase
YLR275W SMD2 0.37 0.9 U1 snRNP protein of the Sm class
YLR034C SMF3 0.37 2.5 S "Putative metal transporter, Nramp homolog, homolog of SMF1 and SMF2"
YJL143W TIM17 0.37 1.1 Mitochondrial inner membrane protein involved in protein import
YGR028W MSP1 0.37 1.3 40 kDa putative membrane-spanning ATPase
YPR040W TIP41 0.37 1.0 SDF1 the first obserwed null phenotype was Sporulation DeFiciency
YJL046W 0.37 1.0
YBR275C RIF1 0.37 2.4 C "RAP1-interacting factor, involved in establishment of repressed chromatin"
YGL225W VRG4 0.37 3.2 K S May regulate Golgi function and glycosylation in Golgi
YMR069W 0.37 1.7
YCL011C GBP2 0.37 0.8 "G-strand Binding Protein
binds single-stranded telomeric repeat sequences in vitro; similar to Gbp1p, a single-stranded telomeric DNA-binding protein from Chlamydomonas reinhardtii"
YIL106W MOB1 0.37 4.6 K S C Mps One Binder
YPL281C ERR2 0.37 1.4 enolase-related subtelomeric sequence (ERR1 and ERR2 code for identical proteins)
YOR393W ERR1 0.37 2.2 enolase-related subtelomeric sequence (ERR1 and ERR2 code for identical proteins)
YLR361C DCR2 0.37 0.9 Dose-Dependent Cell cycle Regulator
YCR100C 0.37 2.9
YJL043W 0.37 2.3
YJL210W PEX2 0.37 1.6 Required for peroxisome biogenesis
YKL143W LTV1 0.37 1.9 Protein required for viability at low temperature
YFR015C GSY1 0.37 2.2 S Highly similar to GSY2. GSY2 is the predominantly expressed glycogen synthase
YDR022C CIS1 0.37 1.7 Involved in microtubule assembly
YLR292C SEC72 0.37 1.3 protein involved in membrane protein insertion into the ER
YLR051C 0.37 1.5
YJL050W MTR4 0.37 1.2 Dead-box family helicase required for mRNA export from nucleus
YML040W 0.37 0.9
YMR169C ALD3 0.37 2.3 "Expression induced in response to heat shock, oxidative and osmotic stress. NAD+ is preferred coenzyme."
YNL092W 0.37 0.8
YFR002W NIC96 0.37 2.3 S "Part of complex at nuclear pore containing in addition NSP1p, NUP49p, and p54"
YIL024C 0.37 1.2
YOR317W FAA1 0.37 2.0 S C cellular lipid metabolism and protein N-myristolation
YML073C RPL6A 0.37 0.9 Homology to rat L6 and human L6
YCL059C KRR1 0.37 1.3 Involved in cell division and spore germination
YDL145C COP1 0.37 1.2 alpha subunit of the coatamer complex; gamma-alpha-COP
YPL213W LEA1 0.37 1.2 Looks Exceptionally like U2A
YHR199C 0.37 0.9
YBR281C 0.37 1.3
YLR454W 0.37 1.7
YOR374W ALD4 0.37 2.8 "Glucose repressed. Utilizes NADP+ or NAD+ as a coenzyme equally well. (sold by SIGMA under the catalogue number A5550, according to A. Blomberg)."
YDR313C PIB1 0.37 1.3 Phosphatidylinositol(3)-phosphate binding
YGL247W BRR6 0.37 1.1 Bad Response to Refrigeration
YCR012W PGK1 0.37 1.7 3-phosphoglycerate kinase
YDL170W UGA3 0.37 0.9 "Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4)"
YGR203W 0.37 0.8
YGL020C MDM39 0.37 1.8 Spore Wall Formation.
Mitochondrial Distribution and Morphology
YIR040C 0.37 1.6
YDR234W LYS4 0.37 1.4 homoaconitase
YJR102C VPS25 0.37 1.5 vacuolar protein sorting (putative)
YGR077C PEX8 0.37 1.4 Required for peroxisome assembly
YKR066C CCP1 0.37 1.5 Cytochrome-c peroxidase
YDL046W 0.37 1.1
YKL082C 0.37 1.8
YHR017W YSC83 0.37 1.0 similar to S. douglasii YSD83
YOR234C RPL33B 0.37 1.3 Homology to rat L35a
YDR201W SPC19 0.37 1.8 Spindle Pole Component of molecular weight 23kDa
YDR365C 0.37 1.4
YOL059W GPD2 0.37 2.1 Involved in glycerol production via conversion of glyerol-3-phosphate and NAD+ to glycerol phosphate and NADH
YHR011W DIA4 0.37 1.9 protein similar to bacterial seryl-tRNA synthases
YBR204C 0.37 2.4 S
YER156C 0.37 1.0
YOR265W RBL2 0.37 1.4 binds to beta-tubulin and may participate in microtubule morphogenesis
YPL143W RPL33A 0.37 1.1 Homology to rat L35a
YKR006C MRPL13 0.37 1.1 mitochondrial ribosomal protein YmL13
YDL147W RPN5 0.37 1.2 "Regulatory Particle Non-ATPase, homolog of mammalian proteasomal subunit p55"
YBR218C PYC2 0.37 1.9 converts pyruvate to oxaloacetate
YMR014W BUD22 0.37 1.2
YOR335C ALA1 0.37 0.8 Cytoplasmic alanyl-tRNA synthetase gene
YGR125W 0.37 1.3
YDR021W FAL1 0.37 2.2 "Similar to eukaryotic initiation factor eIF4a; required for pre-rRNA processing at sites A0, A1, and A2; may be involved in 18S rRNA maturation"
YGR213C RTA1 0.37 1.3 involved in 7-aminocholesterol resistance
YDR145W TAF12 0.37 0.9 TFIID subunit (TBP-associated factor) with predicted molecular weight of 61 kD.
YBL041W PRE7 0.37 1.0 proteasome subunit
YHR147C MRPL6 0.37 1.3 Mitochondrial ribosomal protein MRPL6 (YmL6)
YNL128W TEP1 0.37 1.4 "Similar to human tumor suppressor gene known as TEP1, MMAC1 and PTEN1"
YKL007W CAP1 0.37 1.7 capping - addition of actin subunits
YMR203W TOM40 0.36 1.1 Translocase of Outer Mitochondrial membrane
YAR003W SWD1 0.36 2.6 S C likely involved in chromatin remodeling
member of Set1p complex
YIL096C 0.36 1.1
YMR040W 0.36 1.8
YGL191W COX13 0.36 1.2 Modulates cytochrome c oxidase activity
YJR008W 0.36 1.5
YPR109W 0.36 1.3
YML017W PSP2 0.36 1.3 Polymerase suppressor 2; Suppressors of group II intron-splicing defect.
YPL264C 0.36 2.4 S C
YGL070C RPB9 0.36 1.4 RNA polymerase II subunit
YLR059C REX2 0.36 1.4 RNA exonuclease
YPR061C 0.36 1.2
YKL130C SHE2 0.36 3.0 S C Required for mother cell-specific HO expression
YDL052C SLC1 0.36 1.4 fatty acyltransferase homologous to E. coli plsC gene; functionally complements plsC mutants
YPR060C ARO7 0.36 1.0 chorismate mutase
YAL025C MAK16 0.36 1.5 putative nuclear protein
YOL040C RPS15 0.36 1.9 Homology to rat S15 and E. coli S19
YIL124W AYR1 0.36 1.5 Subcellular location of Ayr1p: lipid particles and endoplasmic reticulum of the yeast
YDR347W MRP1 0.36 1.0 shows allele-specific genetic interactions with pet122 and pet123
YNL111C CYB5 0.36 1.9 S cytochrome b5
YLR074C BUD20 0.36 1.4
YLR151C PCD1 0.36 2.6 S C peroxisomal nudix hydrolase active towards coenzyme A and its derivatives
YNL313C 0.36 2.2
YKL078W DHR2 0.36 1.5 DEAH-box protein involved in ribosome synthesis
YMR312W ELP6 0.36 1.4 "ELongator Protein 6; 30kD subunit. Homolog of ATPases, yet with substitutions of amino acids critical for ATP hydrolysis."
YPR178W PRP4 0.36 1.1 Specific component of the U4/U6 and U4/U6-U5 snRNPs which associates transiently with the spliceosome before the first step of splicing.
YGL145W TIP20 0.36 0.9 transport protein that interacts with Sec20p; required for protein transport from the endoplasmic reticulum to the golgi apparatus
YER043C SAH1 0.36 1.1 putative S-adenosyl-L-homocysteine hydrolase
YBR129C OPY1 0.36 0.9 imparts Far- phenotype
YKR039W GAP1 0.36 5.1 S general amino acid permease
YDL010W 0.36 4.2 S C
YGL141W HUL5 0.36 2.1 ubiquitin-protein ligase (E3)
YOR173W DCS2 0.36 1.4 "Similar to mRNA decapping enzyme, HIT superfamily."
YOL056W GPM3 0.36 1.9 converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis
YLR354C TAL1 0.36 2.0 "Transaldolase, enzyme in the pentose phosphate pathway"
YGR162W TIF4631 0.36 1.1 also called eIF4 (eIF-4) gamma
YOR251C 0.36 1.1
YOR389W 0.36 1.3
YOL021C DIS3 0.36 0.8 Possible component of RCC1-Ran pathway
YGL215W CLG1 0.36 0.8 cyclin-like protein that interacts with Pho85p in affinity chromatography
YPR122W AXL1 0.36 0.9 "determinant in axial budding pattern of haploid cells, involved in processing of a-factor"
YHR037W PUT2 0.36 1.6 delta-1-pyrroline-5-carboxylate dehydrogenase
YCR086W CSM1 0.36 1.7 C Chromosome segregation in meiosis
YKL172W EBP2 0.36 2.8 S EBNA1-binding protein homolog
YER081W SER3 0.36 1.6 catalyzes the first step in serine biosynthesis; isozyme of SER33
YKR076W ECM4 0.36 1.2 ExtraCellular Mutant
YMR279C 0.36 1.2
YGL044C RNA15 0.36 1.6 Protein with a role in mRNA stability and/or poly(A) tail length
YER046W SPO73 0.36 1.1 Sporulation
YER161C SPT2 0.36 1.0 non-specific DNA binding protein (sin1)
YKL211C TRP3 0.36 0.9 anthranilate synthase Component II and indole-3-phosphate (multifunctional enzyme)
YLL040C VPS13 0.36 1.1 C vacuolar Protein Sorting
YML129C COX14 0.36 1.4 "Mitochondrial membrane protein, required for assembly of cytochrome c oxidase"
YML093W UTP14 0.36 1.3 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YLR113W HOG1 0.36 1.2 Osmoregulation. Hog1p is activated under stress conditions when the cAMP cellular content is low.
YPL117C IDI1 0.36 1.4 catalyzes activation step in isoprenoid biosynthetic pathway
YLR205C HMX1 0.36 2.0 Homology to heme oxygenases
YHL040C ARN1 0.36 2.3 S Transporter that specifically recognizes siderophore-iron chelates and is expressed under conditions of iron deprivation.
YBR286W APE3 0.36 0.9 Aminopeptidase yscIII
YHR167W THP2 0.36 1.1 affects transcription elongation
YLR242C ARV1 0.36 2.2 similar to Nup120p and C.elegans R05H5.5 protein and Nup120p
YJL193W 0.35 2.5
YGL037C PNC1 0.35 4.2 S NAD(+) salvage pathway gene
YIL102C 0.35 1.1
YCR060W 0.35 1.2
YGL018C JAC1 0.35 0.9 may be involved in assembly/maturation of mitochondrial iron-sulfur proteins
YMR111C 0.35 0.9
YEL005C VAB2 0.35 1.5 Vac8p binding protein of 31 kDa
YDL045C FAD1 0.35 0.9 "Flavin adenine dinucleotide (FAD) synthetase, which performs second step in synthesis of FAD from riboflavin"
YKR008W RSC4 0.35 2.3 "RSC4 is a member of RSC complex, which remodels the structure of chromatin."
YGR212W 0.35 0.9
YNL175C NOP13 0.35 2.1 Nucleolar Protein 13
YJR044C VPS55 0.35 1.4 Vacuolar Protein Sorting
YPR198W SGE1 0.35 1.1 multi-copy suppressor of gal11 null; member of drug-resistance protein family
YCR027C RHB1 0.35 1.0 rheb homologue
YJR010C-A SPC1 0.35 1.3 Homolog of the SPC12 subunit of mammalian signal peptidase complex. Protein is important for efficient signal peptidase activity.
YLR367W RPS22B 0.35 1.4 Homology to rat S15a
YAL060W BDH1 0.35 2.2 "(2R,3R)-2,3-butanediol dehydrogenase"
YJL055W 0.35 0.9
YDL234C GYP7 0.35 1.8 GTPase-activating protein
YCR002C CDC10 0.35 1.9 S cell division cycle blocked at 36 degree C
YER018C SPC25 0.35 3.1 S C Spindle Pole Component of molecular weight 25kDa
YEL070W 0.35 0.8
YIL049W DFG10 0.35 2.2 "Protein required for filamentous growth, cell polarity, and cellular elongation"
YBR164C ARL1 0.35 1.1 Hydrolyzes GTP; myristylated; in soluble fraction. Part of the carboxypeptidase Y pathway.
YEL066W HPA3 0.35 2.2 Histone and other Protein Acetyltransferase; Has sequence homology to known HATs and NATs
YDR192C NUP42 0.35 1.4 interacts specifically with the HIV-1 Rev protein effector domain;
Ulp1 Interacting Protein 1
YMR295C 0.35 2.1 S
YPL203W TPK2 0.35 1.1 Involved in nutrient control of cell growth and division
YGL237C HAP2 0.35 1.3 Global regulator of respiratory genes
YGL015C 0.35 1.3
YMR034C 0.35 1.5
YER105C NUP157 0.35 1.0 yeast nuclear pore complex component
YGR058W 0.35 0.9
YDR324C UTP4 0.35 1.6 C part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YNL270C ALP1 0.35 2.8 Homologous to permeases Can1p and Lyp1p
YDR131C 0.35 1.3
YHR166C CDC23 0.35 1.1 Required for mitosis and RNA synthesis
YFL052W 0.35 2.6
YHR070W TRM5 0.35 1.0 tRNA modification enzyme
YOR039W CKB2 0.35 1.5 "protein kinase CK2, beta' subunit"
YHR087W 0.35 4.6
YDL045W-A MRP10 0.35 0.9 Involved in mitochondrial translation
YOR116C RPO31 0.35 2.0 RNA polymerase III large subunit
YGL169W SUA5 0.35 1.5 Protein involved in translation initiation
YGL066W SGF73 0.35 1.2 SaGa associated Factor 73kDa
YIL074C SER33 0.35 2.8 S catalyzes the first step in serine biosynthesis; isozyme of SER3
YNR002C FUN34 0.35 1.7 Highly homologous to Ycr010p and similar to Yarrowia lipolytica glyoxylate pathway regulator GPR1 (see MIPS); member of the TC 9.B.33 YaaH family of putative transporters
YNL315C ATP11 0.35 1.9 essential for assembly of a functional F1-ATPase; binds the beta subunit of F1-ATPase.
YPL201C 0.35 1.3
YBL007C SLA1 0.35 1.4 "Involved in assembly of cortical actin cytoskeleton, contains 3 SH3 domains, interacts with Bee1p"
YML124C TUB3 0.35 1.5 alpha-tubulin
YMR055C BUB2 0.35 2.7 S Protein required for cell cycle arrest in response to loss of microtubule function
YPL215W CBP3 0.35 1.1 Protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex)
YGL039W 0.35 1.6
YLL015W BPT1 0.35 0.9 bile pigment transporter
YDR308C SRB7 0.35 2.2 "Suppressor of RNA polymerase II, possible component of the holoenzyme"
YBR126C TPS1 0.35 2.4 "Probable regulator of glucose influx into the cell & into glycolytic pathway, indirectly regulating glucose-induced signalling (activation & inactivation) & initial step(s) of glucose metabolism. Homologue of E. coli otsA protein"
YPL076W GPI2 0.35 1.2 "Required for synthesis of N-acetylglucoaminylphosphatidylinositol, the first intermediate in synthesis of glycosylphosphatidylinositol (GPI) anchors"
YMR315W 0.35 1.9
YPR100W 0.35 1.4
YOR271C 0.35 1.0
YFL066C 0.35 2.9 S
YML054C CYB2 0.35 1.3 "Expression is repressed by glucose and anaerobic conditions, is induced by L-lactate and is regulated by GRR1, ROX3, HAP1, HXK2 and CYC8"
YIL070C MAM33 0.35 1.4 33-kDa mitochondrial acidic matrix protein
YNL191W 0.35 1.8
YPR113W PIS1 0.35 2.0 phosphatidylinositol synthase
YBR103W SIF2 0.35 1.8 Sir4p-Interacting Factor
YLR460C 0.35 1.4
YCR093W CDC39 0.35 0.9 Required for Start B in mitosis and spindle pole body separation at meiosis I
YFR008W 0.34 1.0
YJL148W RPA34 0.34 1.9 "RNA polymerase I subunit, not shared (A34.5)"
YBR104W YMC2 0.34 1.2 C Mitochondrial carrier protein
YJL190C RPS22A 0.34 2.1 Homology to rat S15a
YKL061W 0.34 1.1
YKR004C ECM9 0.34 1.4 ExtraCellular Mutant
YNR071C 0.34 1.0
YGR207C 0.34 1.2
YNL224C 0.34 0.9
YLR008C 0.34 1.0
YDL067C COX9 0.34 1.5 Plays role in cytochrome c oxidase holoenzyme assembly or stability
YPR160W GPH1 0.34 2.7 S Releases glucose-1-phosphate from glycogen
YNL331C AAD14 0.34 1.1 aryl-alcohol dehydrogenase located on chromosome 14
YJR012C 0.34 1.2
YGL034C 0.34 2.2
YGR009C SEC9 0.34 0.9 Putative t-SNARE of the plasma membrane
YKR058W GLG1 0.34 1.2 self-glucosylating initiator of glycogen synthesis; similar to mammalian glycogenin
YOL164W 0.34 1.2
YIL028W 0.34 0.8
YDL071C 0.34 1.0
YMR274C RCE1 0.34 2.8 Protease involved in ras and a-factor terminal proteolysis
YGR253C PUP2 0.34 0.9 Proteasome subunit
YDR015C 0.34 2.0
YNL132W KRE33 0.34 1.2 Killer toxin REsistant
YPR002W PDH1 0.34 2.3 C "prpD homologue; (62% identical to the prpD genes of Escherichia coli and Salmonella typhimurium, which play an unknown but essential role in propionate catabolism)"
YPL046C ELC1 0.34 1.2 "similar to mammalian elongin C, interacts with elongin A"
YDR541C 0.34 1.4
YBR110W ALG1 0.34 2.5 "beta-1,4-mannosyltransferase"
YOL020W TAT2 0.34 1.1 "Tryptophan permease, high affinity"
YLL023C 0.34 1.2
YDL213C FYV14 0.34 2.0 Function required for Yeast Viability on toxin exposure
YPR114W 0.34 1.2
YNL048W ALG11 0.34 1.4 "Specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-Glycosylation intermediate"
YDR263C DIN7 0.34 1.2 DNA-damage inducible gene
YDR252W BTT1 0.34 2.0 C beta subunit of the nascent-polypeptide-associated complex (NAC); homologous to human BTF3b; Negative effect on expression of several genes transcribed by RNA polymerase II
YKL003C MRP17 0.34 1.2 Mitochondrial ribosomal protein MRP17
YPL103C 0.34 0.9
YDR178W SDH4 0.34 1.6 "Yeast succinate dehydrogenase (SDH) is a tetramer of non-equivalent subunits--Sdh1p, Sdh2p, Sdh3p, Sdh4p--that couples the oxidation of succinate to the transfer of electrons to ubiquinone."
YML021C UNG1 0.34 3.4 K S C uracil DNA glycosylase
YJL170C ASG7 0.34 3.7 an a-specific gene that is induced to a higher expression level by alpha factor
YLR258W GSY2 0.34 2.8 C Highly similar to GSY1. GSY2 is the predominantly expressed glycogen synthase. Activity is probably regulated by cAMP-dependent and SNF1 protein kinases and type 1 phosphatase
YOL110W SHR5 0.34 0.9 Involved in RAS localization and palmitoylation
YMR159C APG16 0.34 2.9 autophagy
YLR250W SSP120 0.34 1.8 secretory protein
YJL011C RPC17 0.34 0.9 Sspecific subunit of Pol III which participates together with C34 in the recruitment of Pol III by the preinitiation complex.
YHL039W 0.34 1.3
YPL054W LEE1 0.34 2.5 S Product of gene unknown
YOL044W PEX15 0.34 1.6 44 kDa phosphorylated integral peroxisomal membrane protein
YGR205W 0.34 2.3
YDR071C 0.34 1.6
YML127W RSC9 0.34 1.4 Remodels the Structure of Chromatin
YPL276W 0.34 1.2
YOL142W RRP40 0.34 1.2 Ribosomal RNA Processing
YLR159W 0.34 2.8
YLR156W 0.34 1.8
YMR170C ALD2 0.34 1.0 Expression induced in response to high osmotic stress. NAD+ is preferred coenzyme.
YOR204W DED1 0.34 1.3 "ATP-dependent RNA helicase of DEAD box family; suppressor of a pre-mRNA splicing mutation, prp8-1"
YML085C TUB1 0.34 3.3 alpha-tubulin
YPL191C 0.34 1.7
YDR405W MRP20 0.34 0.9 Involved in mitochondrial translation
YBL026W LSM2 0.34 1.7 Like Sm-D1 protein
YCR020C-A MAK31 0.34 0.9 "Like Sm protein; member of the Sm protein family, though slightly divergent because Mak31/Lsm9p does not contain a glycine or cysteine at amino acid 107."
YMR051C 0.34 0.8
YJL147C 0.34 1.0
YEL064C 0.34 2.7 S
YOL093W 0.34 1.4
YDL069C CBS1 0.34 1.1 translational activator of cytochrome b
YOR143C THI80 0.34 1.4 Thiamin pyrophosphokinase
YIR032C DAL3 0.34 1.7 ureidoglycolate hydrolase
YDR321W ASP1 0.34 1.2 "Asparaginase I, intracellular isozyme"
YOL116W MSN1 0.34 1.5 multicopy supressor of snf1 and sta10 mutations
YMR116C ASC1 0.34 1.9 WD repeat protein (G-beta like protein) that interacts with the translational machinery
YDR400W URH1 0.34 3.5 S uridine nucleosidase (uridine ribohydrolase); EC 3.2.2.3
YLL017W 0.34 1.7
YPL149W APG5 0.34 1.2 Involved in autophagy
YNL306W MRPS18 0.34 0.9
YER185W 0.34 1.4
YJR137C ECM17 0.34 3.6 S C ExtraCellular Mutant
YOR020C HSP10 0.34 1.3 "Homolog of E. coli GroES protein; regulates Hsp60, the yeast mitochondrial chaperonin, and is thereby involved in protein folding and sorting in mitochondria"
YGR129W SYF2 0.34 2.1 SYnthetic lethal with cdcForty
YGR251W 0.34 0.8
YBR211C AME1 0.34 1.7 associated with microtubules and essential
YDL200C MGT1 0.34 1.4 6-O-methylguanine-DNA methylase
YJR136C 0.33 1.5
YOL123W HRP1 0.33 2.1 Putative polyadenylated-RNA-binding protein located in nucleus; similar to vertebrate hnRNP A/B protein family
YOL151W GRE2 0.33 2.3 induced by osmotic stress; similar to dihydroflavonol 4-reductase from plants
YOR182C RPS30B 0.33 1.8 Homology to mammalian S30
YLR287C-A RPS30A 0.33 1.7 Homology to mammalian S30
YBR149W ARA1 0.33 2.2 D-arabinose dehydrogenase
YNL141W AAH1 0.33 1.7 adenine aminohydrolase (adenine deaminase)
YML011C 0.33 1.6
YOR190W SPR1 0.33 1.8 Sporulation regulated genes
YDR514C 0.33 1.0
YDR141C DOP1 0.33 1.4 "homolog of Emericella nidulans developmental regulatory gene, dopey (dopA)."
YPR131C NAT3 0.33 1.2 "Non-essential gene, growth of null mutants is retarded on both YPD & YPG media. The mating efficiency of MATalpha cells, but not MATa cells, is reduced by nearly three orders of magnitude."
YPR128C ANT1 0.33 2.8 S adenine nucleotide transporter
YLR264W RPS28B 0.33 1.0 Homology to mammalian S28
YGR157W CHO2 0.33 1.2 First step in the methylation pathway for phosphatidylcholine biosynthesis
YDR102C 0.33 1.3
YKR074W 0.33 1.0
YMR228W MTF1 0.33 1.1 Mitochondrial RNA polymerase specificity factor
YNL161W CBK1 0.33 1.3 cell wall biosynthesis kinase
YBR094W 0.33 2.4 S
YLR271W 0.33 0.9
YNL210W MER1 0.33 1.6 "Disp. for axial elements in meiosis but required for full chr. pairing & chr. condensation seen by in situ hybridization, wt level of synaptonemal complexes, heteroduplex DNA, gene conversion & reciprocal recombination & spore viability"
YBL001C ECM15 0.33 2.7 ExtraCellular Mutant
YEL004W YEA4 0.33 1.8 "Shows sequence similarity to GOG5, a gene involved in vanadate resistance"
YHL047C ARN2 0.33 1.0 Siderophore transporter for triacetylfusarinine C
YPL262W FUM1 0.33 1.4 Fumarase converts l-malate to fumarate as part of the TCA cycle
YMR076C PDS5 0.33 3.6 S C Precocious Dissociation of Sister chromatids
YLR340W RPP0 0.33 2.5 "Homology to rat P0, human P0, and E. coli L10e"
YGL096W TOS8 0.33 1.3 Target of SBF
YPR167C MET16 0.33 2.7 S C 3'phosphoadenylylsulfate reductase
YGR076C MRPL25 0.33 1.1 Mitochondrial ribosomal protein MRPL25 (YmL25)
YGR186W TFG1 0.33 1.1 Transcription factor TFIIF large subunit
YDR407C TRS120 0.33 1.1 targeting complex (TRAPP) component involved in ER to Golgi membrane traffic
YOR326W MYO2 0.33 2.3 class V myosin
YOR311C HSD1 0.33 1.8 ER membrane protein
YMR285C NGL2 0.33 1.2 correct 3'-end formation of 5.8S rRNA at site E is strictly dependent on Ngl2p.
YCR104W PAU3 0.33 1.5 member of the seripauperin protein/gene family (see Gene_class PAU)
YNL004W HRB1 0.33 0.8 an ORF of unknown function located in a centromeric region duplicated between chromosomes III and XIV
YPR072W NOT5 0.33 0.8 "member of the NOT complex, a global negative regulator of transcription"
YFL010W-A AUA1 0.33 1.7 Involved in ammonia regulation of GAP1 activity
YBR252W DUT1 0.33 1.5 C dUTP metabolism
YHR209W 0.33 2.0
YDR127W ARO1 0.33 0.8 "pentafunctional arom polypeptide (contains: 3-dehydroquinate synthase, 3-dehydroquinate dehydratase (3-dehydroquinase), shikimate 5-dehydrogenase, shikimate kinase, and epsp synthase)"
YNL172W APC1 0.33 2.6 S anaphase-promoting complex component
YFR007W 0.33 1.1
YGR277C 0.33 1.4
YBR236C ABD1 0.33 1.2 RNA (guanine-7-)methyltransferase (cap methyltransferase)
YGR255C COQ6 0.33 1.8 Involved in ubiquinone biosynthesis
YPR147C 0.33 1.3
YOR115C TRS33 0.33 1.6 S Trapp subunit of 33 kDa
YKL209C STE6 0.33 2.3 S "ABC transporter, glycoprotein, component of a-factor secretory pathway"
YGR168C 0.33 1.7
YOR147W MDM32 0.33 1.2 Mitochondrial Distribution and Morphology
YLR168C 0.33 2.1
YJL026W RNR2 0.33 1.1 small subunit of ribonucleotide reductase
YKL056C 0.33 1.7
YDR350C TCM10 0.33 0.9 Product of gene unknown
YBR016W 0.33 1.8
YPL055C LGE1 0.33 1.6 large cell size mutant
YKL167C MRP49 0.33 1.3 16 kDa mitochondrial ribosomal large subunit protein
YBL015W ACH1 0.33 0.9 Mannose-containing glycoprotein which binds concanavalin A
YGL222C EDC1 0.33 1.6 Enhancer of mRNA Decapping
YHR084W STE12 0.33 1.6 Involved in pheromone and pseudohyphal growth signal transduction pathways
YDR432W NPL3 0.33 1.6 S "involved as a protein carrier in mRNA export, involved in mitochondrial protein targeting"
YKL184W SPE1 0.33 1.5 Rate limiting step of polyamine biosynthesis pathway
YNL023C FAP1 0.33 1.1 FKBP12-associated protein
YKL223W 0.33 2.2
YJR122W CAF17 0.33 1.2 CCR4 associated factor
YLR070C XYL2 0.33 1.4 XYLitol Dehydrogenase
YDR408C ADE8 0.33 0.9 glycinamide ribotide transformylase
YCR024C-A PMP1 0.33 5.2 S May regulate plasma membrane H(+)-ATPase
YBL069W AST1 0.33 3.3 Protein involved in targeting of plasma membrane [H+]ATPase
YGR155W CYS4 0.33 1.0 encodes the first enzyme in cysteine biosynthesis
YKL035W UGP1 0.33 3.1 S EC:2.7.7.9
UDP-glucose pyrophosphorylase or UTP-glucose-1-phosphate uridylyltransferase
YER101C AST2 0.33 0.8 Protein involved in targeting of plasma membrane [H+]ATPase
YJR069C HAM1 0.33 1.0 Product of gene unknown
YNL200C 0.33 3.0
YLR117C CLF1 0.33 0.8 "SYnthetic lethal with cdcForty; Crooked neck Like Factor, an ortholog of the Drosophila crooked neck gene, crn"
YML110C COQ5 0.33 3.2 S C co-enzyme Q deficient
YMR013C SEC59 0.33 1.5 "catalyzes the CTP-mediated phosphorylation of dolichol, the terminal step in dolichyl monophosphate (Dol-P) biosynthesis. required for viability, normal rates of lipid intermediate synthesis, protein N-glycosylation."
YPL171C OYE3 0.33 2.0 Old yellow enzyme
YKL120W OAC1 0.33 1.8 oxaloacetate carrier
YGL246C RAI1 0.33 1.4 Product of gene unknown
YAL032C PRP45 0.33 1.0 "protein required for pre-mRNA splicing in vivo and in vitro, associated with the spliceosome, weakly associated with U2, U5 and U6 snRNPs"
YKR063C LAS1 0.33 1.0 May regulate expression of genes involved in bud formation and morphogenesis
YJL213W 0.33 0.8
YOR167C RPS28A 0.33 1.9 Homology to mammalian S28
YGL127C SOH1 0.33 1.7 "Soh1p has limited sequence similarity to RNA polymerases and interacts with a DNA repair protein, Rad5p, in a two-hybrid system assay; may provide a link between recombination in direct repeats and transcription"
YGL224C SDT1 0.33 1.1 suppressor of deletion of TFIIS
YPL263C KEL3 0.33 1.5 "Kelch-repeat protein, similar to Kel1 and Kel2"
YNL156C 0.32 0.8
YNL241C ZWF1 0.32 1.3 Glucose-6-phosphate dehydrogenase
YOL126C MDH2 0.32 1.8 cytosolic malate dehydrogenase
YKL142W MRP8 0.32 2.8 mitochondrial ribosomal protein
YLR201C 0.32 1.6
YDL029W ARP2 0.32 1.4 Involved in endocytosis and membrane growth and polarity
YLR007W NSE1 0.32 1.1 non-SMC element 1. essential for cell proliferation.
YHR194W MDM31 0.32 0.9 Mitochondrial Distribution and Morphology
YCR034W FEN1 0.32 2.5 C "Involved in synthesis of 1,3-beta-glucan, a component of the cell wall, and elongation of fatty acids up to 24 carbons"
YOR349W CIN1 0.32 0.9 "Protein involved in chromosome segregation, required for microtubule stability"
YFR031C-A RPL2A 0.32 1.0 Homology to rat L8 and E. coli L2
YDL193W 0.32 1.6
YIR035C 0.32 1.9
YKL206C 0.32 0.9
YCR081W SRB8 0.32 1.2 activation mediator subcomplex of RNA polymerase I holoenzyme
YJR140C HIR3 0.32 0.9 Involved in cell-cycle regulation of histone transcription
YNR027W BUD17 0.32 0.8
YOR064C YNG1 0.32 1.8 Yeast homolog of mammalian Ing1
YDL246C 0.32 0.9
YNL112W DBP2 0.32 1.8 ATP-dependent RNA helicase of DEAD box family
YOL039W RPP2A 0.32 1.0 "Homology to rat P2, human P2, and E.coli L12eIB"
YBL093C ROX3 0.32 1.3 RNA polymerase II holoenzyme/mediator subunit
YGL004C 0.32 1.2
YBL064C 0.32 2.9 S
YOL008W 0.32 2.2
YLR247C 0.32 1.4
YBR096W 0.32 1.6
YBR019C GAL10 0.32 1.5 UDP-glucose 4-epimerase
YDR468C TLG1 0.32 1.0 member of the syntaxin family of t-SNAREs
YHR106W TRR2 0.32 2.2 S mitochondrial thioredoxin reductase
YOL049W GSH2 0.32 1.0 Glutathione Synthetase
YGR037C ACB1 0.32 1.8 Involved in transport of newly synthesized acyl-CoA esters from the fatty acid synthetase to acyl-CoA-consuming processes
YML001W YPT7 0.32 1.5 "Gtp-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, and for fusion of endosomes to vacuoles when expressed from high copy plasmid"
YBR034C HMT1 0.32 1.0 hnRNP methyltransferase
YNL010W 0.32 0.9
YKL221W MCH2 0.32 1.4 monocarboxylate permease homologue
YHR210C 0.32 1.4
YJL167W ERG20 0.32 1.2 May be rate-limiting step in sterol biosynthesis pathway
YFL034C-B MOB2 0.32 0.8 Mps One Binder
YER153C PET122 0.32 1.3 translational activator of cytochrome c oxidase subunit III
YDR287W 0.32 1.2
YKL224C 0.32 1.1
YMR240C CUS1 0.32 0.8 cold sensitive U2 snRNA Suppressor
YCR075C ERS1 0.32 2.1 Suppressor of ERD1 mutation; seven transmembrane domain protein
YBR108W 0.32 4.3 S
YHR162W 0.32 1.2
YDR513W TTR1 0.32 1.6 Glutaredoxin (thioltransferase) (glutathione reductase)
YAL061W 0.32 1.5
YIL104C SHQ1 0.32 2.3 S required for SnoRNAs of the box H/ACA Quantitative accumulation
YBR035C PDX3 0.32 0.9 pyridoxine (pyridoxiamine) phosphate oxidase
YGL220W 0.32 1.0
YER141W COX15 0.32 1.2 cytochrome oxidase assembly factor
YOR294W RRS1 0.32 1.0 Regulator for ribosome synthesis
YNL223W AUT2 0.32 1.5 Involved in autophagy. Interacts with Tub1p and Tub2p and forms a complex with Aut7p. Required for sporulation.
YMR183C SSO2 0.32 2.9 S SSO1 and SSO2 encode syntaxin homologs (post-Golgi t-SNAREs); act in late stages of secretion
YDR512C EMI1 0.32 1.9 Early Meiotic Induction
YOR285W 0.32 1.2
YHR013C ARD1 0.32 0.9 subunit of the major N alpha-acetyltransferase; complexes with Nat1p
YJL203W PRP21 0.32 1.1 RNA splicing factor
YAR073W IMD1 0.32 1.8 IMP dehydrogenase homolog
YPR085C 0.32 1.0
YBR053C 0.32 3.2 S C
YGR043C 0.32 1.6
YMR288W HSH155 0.32 0.8
YEL035C UTR5 0.32 2.1 Product of gene unknown
YOR329C SCD5 0.32 1.2 Multicopy suppressor of clathrin deficiency and of ts mutants of IPL1
YLR179C 0.32 1.5
YKL194C MST1 0.32 1.5 mitochondrial threonine-tRNA synthetase
YGL053W PRM8 0.32 1.8 pheromone-regulated membrane protein
YFL065C 0.32 3.8 S
YNL262W POL2 0.32 5.2 K Z S C DNA polymerase II
YJR011C 0.32 1.6
YDR480W DIG2 0.32 2.5 "Down-regulator of Invasive Growth, Regulator of Sterile Twelve"
YFL040W 0.32 1.6
YNL227C 0.31 1.3
YMR247C 0.31 1.1
YPR041W TIF5 0.31 1.4 "eIF5 mediates hydrolysis of eIF2-GTP (SUI2,SUI3,GCD11) at start codons"
YOR340C RPA43 0.31 1.5 DNA-dependent RNA polymerase I subunit A43
YGL198W 0.31 1.0
YER131W RPS26B 0.31 1.9 Homology to rat S26
YCR007C 0.31 2.8
YML092C PRE8 0.31 1.1 proteasome component Y7
YOR193W 0.31 1.2
YER117W RPL23B 0.31 1.3 Homology to rat L23 and E. coli L14
YOR242C SSP2 0.31 1.1 S Sporulation SPecific
YBL087C RPL23A 0.31 1.9 Homology to E. coli L14 and rat L23
YML047C PRM6 0.31 2.2 pheromone-regulated membrane protein
YLR295C ATP14 0.31 0.8 ATP synthase subunit h
YPR158W 0.31 1.4
YNR074C 0.31 1.3
YHL001W RPL14B 0.31 1.0 Homology to mammalian L14
YCL064C CHA1 0.31 4.6 catabolism of hydroxy amino acids
YDL082W RPL13A 0.31 1.0 Homology to rat L13
YGL022W STT3 0.31 2.3 Required for protein glycosylation
YLL048C YBT1 0.31 1.4 "Yeast bile transporter, similar to mammalian bile transporter"
YMR318C ADH6 0.31 1.2 NADPH-dependent alcohol dehydrogenase
YOR213C SAS5 0.31 0.9 "Involved in silencing at telomeres, HML and HMR"
YFR038W 0.31 1.5 C
YGL040C HEM2 0.31 1.2 "converts delta-aminolevulinic acid to porphobilinogen, an intermediate in the synthesis of heme"
YDR441C APT2 0.31 0.8 similar to adenine phosphoribosyltransferase; appears to be a nonfunctional pseudogene
YLR016C 0.31 1.4
YMR022W QRI8 0.31 1.6 part of the HRDDER pathway of ER-associated protein degradation
YBR175W SWD3 0.31 1.2 likely involved in chromatin remodeling
member of Set1p complex
YDR302W GPI11 0.31 3.3 Z S Glycosylphosphatidylinositol (GPI) assembly
YKL197C PEX1 0.31 1.1 member of the AAA-protein family
YJR033C RAV1 0.31 1.1 Regulator of (H+)-ATPase in vacuolar membrane
YJR014W 0.31 1.0
YDR511W ACN9 0.31 1.9 C
YMR027W HRT2 0.31 0.8 "High level expression reduced Ty3 Transposition. Do not confuse with HRT1/HRT2/RBX1/ROC1/YOL133W, which has been referred to as HRT2 in Swaroop et al (2000) Oncogene 19:2855-66."
YNL052W COX5A 0.31 1.0 "One of two genes (COX5A and COX5B, both nuclear-encoded) coding for subunit V of cytochrome c oxidase; COX5A gene product is the predominantform of subunit V found in holocytochrome c oxidase under normal growth conditions"
YML053C 0.31 1.9
YDR357C 0.31 1.8
YCL047C 0.31 1.3
YBL004W UTP20 0.31 2.4 U3 protein
YDR066C 0.31 1.3
YKL186C MTR2 0.31 1.3 mRNA transport regulator
YIR029W DAL2 0.31 0.9 allantoicase
YDR435C PPM1 0.31 1.4 carboxy methyl transferase for protein phosphatase 2A catalytic subunit
YKR049C 0.31 1.8
YPL134C ODC1 0.31 1.8 Oxodicarboxylate carrier
YML079W 0.31 1.2
YHR191C CTF8 0.31 1.2 (putative) kinetochore protein
YBR076W ECM8 0.31 0.8 ExtraCellular Mutant
YJL154C VPS35 0.31 1.3 Protein involved in vacuolar sorting
YBL088C TEL1 0.31 1.8 Involved in controlling telomere length; ataxia telangiectasia (ATM) gene homolog
YNR058W BIO3 0.31 1.4 biotin biosynthesis
YDR023W SES1 0.31 1.0 seryl-tRNA synthetase
YDL233W 0.31 1.3
YER042W MXR1 0.31 3.0 S peptide Methionine sulfoXide Reductase 1
YLR326W 0.31 3.9 Z S C
YDR341C 0.31 0.9
YMR030W 0.31 2.1
YOR257W CDC31 0.31 1.4 "Required for spindle pole body duplication and mitosis in meiosis II; calcium-binding protein component of spindle pole bodies, localizes to half-bridges and interacts with KAR1"
YIR041W 0.31 1.2
YKL132C 0.31 2.2
YBR228W SLX1 0.31 1.2
YGR214W RPS0A 0.31 1.4 Homology to rat Sa
YFL061W 0.31 2.5
YNL335W 0.31 1.5
YDL102W CDC2 0.31 3.0 K S "essential for mitotic and meiotic DNA synthesis, dispensable for meiotic spindle pole body duplication, but required for synaptonemal complexes and full intragenic recombination, spindle pole body separation and spindle formation"
YIL009W FAA3 0.31 4.8 S C "acyl-CoA synthetase (long-chain fatty acid CoA ligase) (fatty acid activator 3), activates endogenous but not imported fatty acids and provides substrates for N-myristoylation"
YMR189W GCV2 0.31 3.5 S Glycine CleaVage system
YPL012W RRP12 0.31 1.1 Required for normal pre-rRNA Processing. Member of a group of seven genes whose expression is repressed during growth on glucose before and during the diauxic shift.
YDR502C SAM2 0.31 1.9 methionine biosynthesis regulation
YBR253W SRB6 0.31 0.9 involved in transcription as part of Srb/Mediator complex
YLR404W 0.31 1.0
YJR100C 0.31 0.8
YDR135C YCF1 0.31 1.1 Metal resistance protein with similarity to human cystic fibrosis protein CFTR and multidrug resistance proteins
YIL119C RPI1 0.31 4.4 S inhibitor of ras
YIR013C GAT4 0.31 1.6 very short and so far mRNA can't be detected
YPL063W 0.31 0.8
YPR183W DPM1 0.31 2.5 dolichol phosphate mannose synthase
YDR364C CDC40 0.31 1.1 "Required for proper timing of DNA synthesis at all temperatures and completion of DNA synthesis at a restrictive temperature in both mitosis and meiosis, and for completion of meiotic recombination, meiosis I, meiosis II and spores"
YNL110C NOP15 0.30 1.5 Nucleolar protein 15
YBL020W RFT1 0.30 1.5 67 kDa integral membrane protein
YLR307W CDA1 0.30 1.1 Required for proper formation of the ascospore wall
YLR276C DBP9 0.30 1.1 Dead-Box Protein 9
YNL195C 0.30 1.5
YLR243W 0.30 1.1
YGL073W HSF1 0.30 1.2 heat shock transcription factor
YLR136C TIS11 0.30 2.9 "Zinc finger containing homolog of mammalian TIS11, glucose repressible gene"
YOR087W YVC1 0.30 1.5 vacuolar cation channel
YER123W YCK3 0.30 1.2 plasma membrane-bound casein kinase I homolog
YLR128W 0.30 1.3
YER174C GRX4 0.30 1.2 "Member of a glutaredoxin subfamily in Sc together with GRX3 & GRX5. Significant sequence diff. with the other glutaredoxin subfamily, formed by the previously described GRX1 & GRX2 glutaredoxins (Luikenhuis MBC 9:1081, 1998)"
YJR057W CDC8 0.30 1.3 K "essential for mitotic DNA synthesis. Required for premeiotic DNA synthesis, synaptonemal complexes, recombination, meiosis I, meiosis II, and spores"
YGR254W ENO1 0.30 1.6 enolase I
YER142C MAG1 0.30 1.3 3-methyladenine DNA glycosylase
YHR153C SPO16 0.30 4.7 Z S C Early meiotic protein required for efficient spore formation
YHR091C MSR1 0.30 1.3 Nuclear-encoded mitochondrial protein
YLR462W 0.30 4.9 Z S
YGR178C PBP1 0.30 0.8 Poly(A)-binding protein binding protein
YLR043C TRX1 0.30 0.9 thioredoxin
YDR489W 0.30 2.0
YGL205W POX1 0.30 0.8 fatty-acyl coenzyme A oxidase
YLR372W SUR4 0.30 2.6 Z S Required for conversion of 24-carbon fatty acids to 26-carbon species
YBR251W MRPS5 0.30 1.5 Probable mitochondrial ribosomal protein S5
YGR078C PAC10 0.30 1.2 "Polypeptide 3 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex"
YIL161W 0.30 1.4
YBR208C "DUR1,2" 0.30 1.5 Urea amidolyase (contains urea carboxylase and allophanate hydrolase)
YPR033C HTS1 0.30 0.9 Nuclear gene that specifies two messages for cytoplasmic and mitochondrial forms
YMR271C URA10 0.30 1.5 Fifth step in pyrimidine bio5
YJR108W ABM1 0.30 0.9 aberrant microtubules
YDR354W TRP4 0.30 1.3 anthranilate phosphoribosyl transferase
YKL006W RPL14A 0.30 0.9 Homology to mammalian L14
YGR072W UPF3 0.30 1.7 factor stimulating decay of mRNAs containing premature stop codons; acts with Nmd2p and Nam7p
YOL076W MDM20 0.30 1.7 Mitochondrial distribution and morphology
YIR015W RPR2 0.30 1.2 RNase P Ribonucleoprotein - name given to subunits that are unique to RNase P (not subunits of RNase MRP)
YER066W 0.30 1.2
YBR029C CDS1 0.30 1.3 "CDP-diacylglycerol synthase, CTP-phosphatidic acid cytidylyltransferase, CDP-diglyceride synthetase"
YCR010C ADY2 0.30 1.3 Accumulation of DYads; member of the TC 9.B.33 YaaH family of putative transporters
YJR135C MCM22 0.30 1.5 Required for maintenance of chromosomes and minichromosomes
YKR081C RPF2 0.30 1.8
YJR070C 0.30 1.4
YDL232W OST4 0.30 1.5 subunit or accessory component of oligosaccharyltransferase
YKL059C MPE1 0.30 1.4 Protein required for cell viability
YCL057W PRD1 0.30 0.9 Saccharolysin (oligopeptidase yscD)
YBR024W SCO2 0.30 1.3 Originally identified as a multicopy suppressor of a respiratory defective mutant; homolog of Sco1p
YMR066W SOV1 0.30 0.9 Synthesis Of Var
YML046W PRP39 0.30 1.4 May function to facilitate or stabilize the interaction between U1 snRNP and the 5' splice site in pre-mRNAs
YBR227C MCX1 0.30 1.5 "Mitochondrial ATP-binding protein, similar to ClpX"
YPL048W CAM1 0.30 1.2 Calcium and phospholipid binding protein homologous to translation elongation factor 1-gamma (EF-1gamma)
YLL025W 0.30 1.4
YBR243C ALG7 0.30 4.0 Z S ER protein that transfers Glc-Nac-P from UDP-GlcNac to Dol-P
YDR177W UBC1 0.30 1.2 ubiquitin-conjugating enzyme
YBR293W 0.30 0.8
YDL002C NHP10 0.30 1.1 Non-Histone Protein 10
YDL235C YPD1 0.30 0.9 Ypd1p is an intermediate protein between Sln1p and Ssk1p in the phosphorelay reaction.
YBR210W 0.30 0.9
YBR097W VPS15 0.30 1.4 myristoylated protein kinase involved in vacuolar protein sorting
YHR179W OYE2 0.30 1.6 "NAPDH dehydrogenase (old yellow enzyme), isoform 2"
YOR266W PNT1 0.30 0.9 Involved in targeting of proteins to the mitochondrial inner membrane; Pentamidine resistance protein
YIL166C 0.30 1.7
YGL248W PDE1 0.30 0.9 "3',5'-Cyclic-nucleotide phosphodiesterase, low affinity"
YNL038W GPI15 0.30 1.5 Glysosyl Phosphatidyl Inositol
YFR052W RPN12 0.30 1.2 Part of 26S proteasome complex that may activate Cdc28p
YJR145C RPS4A 0.30 2.3 Homology to rat S4 and human S4
YPL111W CAR1 0.30 2.5 S arginase
YOR164C 0.30 0.8
YGL189C RPS26A 0.30 2.8 Homology to rat S26
YGR132C PHB1 0.30 0.9 antiproliferative protein involved in determination of replicative life span
YLR403W SFP1 0.30 2.0 Inhibits nuclear protein localization when present in multiple copies
YPL025C 0.30 2.3 S
YJR034W PET191 0.30 1.0 Required for assembly of active cytochrome c oxidase
YPR057W BRR1 0.30 1.7 Protein involved in snRNP biogenesis
YKR052C MRS4 0.30 1.1 "mitochondrial carrier protein, highly homologous to Mrs3p"
YDR185C 0.30 0.9
YPL051W ARL3 0.30 1.2 Similar to ADP-ribosylation factor. Part of the carboxypeptidase Y pathway.
YOR314W 0.30 4.0 S
YJL003W COX16 0.30 1.1 Cytochrome oxidase assembly
YBR144C 0.30 1.7
YPR164W MMS1 0.30 1.7 "sensitive to methyl methanesulfonate (MMS), diepoxybutane, and mitomycin C"
YPL232W SSO1 0.30 2.3 S SSO1 and SSO2 encode syntaxin homologs (post-Golgi t-SNAREs); act in late stages of secretion
YDR368W YPR1 0.30 2.2 S C homologous to the aldo-keto reductase protein family
YLR450W HMG2 0.29 1.8 Induces cells to assemble peripheral ER membrane arrays and short nuclear-associated membrane stacks. Rate-limiting enzyme in sterol biosynthesis.
YGL232W 0.29 1.0
YOR181W LAS17 0.29 1.1 "Homolog of human WASP, proline-rich protein"
YNL015W PBI2 0.29 3.9 S Proteinase inhibitor that inhibits protease Prb1p (yscB or IB2)
YDR161W TCI1 0.29 1.2 protein phosphatase Two C-Interacting protein
YOR246C 0.29 2.2
YHR044C DOG1 0.29 1.4 2-deoxyglucose-6-phosphate phosphatase
YOL009C MDM12 0.29 1.8 Required for normal mitochondrial morphology and distribution
YOR354C MSC6 0.29 1.8 Meiotic Sister-Chromatid recombination
YMR314W PRE5 0.29 1.1 alpha-type of subunit of 20S proteasome
YBR105C VID24 0.29 1.0 also involved in vacuolar protein targeting
YDR254W CHL4 0.29 1.7 Protein necessary for stability of ARS-CEN plasmids; suggested to be required for kinetochore function
YOL160W 0.29 1.2
YGR224W AZR1 0.29 1.5 MFS-MDR
YNL162W RPL42A 0.29 1.0 Homology to rat L36a and human L36a
YHR141C RPL42B 0.29 0.9 Homology to rat L36a and human L36a
YPR094W RDS3 0.29 1.3 Protein required for cell viability
YBR011C IPP1 0.29 1.0 Inorganic pyrophosphatase
YFR004W RPN11 0.29 1.1 Suppressor of mutant (ts on glycerol) tRNA gene deficient in the processing of its 3'-end; homologous to S. pombe PAD1 gene - global positive regulator of nuclear transcription and is involved in maintenance of chromatin structure
YDL112W TRM3 0.29 1.5 Trna ribose methylase
YKL029C MAE1 0.29 2.7 Mitochondrial malic enzyme
YMR187C 0.29 0.8
YLR329W REC102 0.29 1.2 "Dispensable for mitotic recombination, DNA damage repair, axial elements & meiotic chromosome condensation; required for wild-type level of chromosome pairing seen by in situ hybridization, tripartite synaptonemal complexes"
YBR194W 0.29 1.4
YEL016C 0.29 2.0
YNL126W SPC98 0.29 4.3 S C Involved in microtubule organization by the SBP
YDR032C PST2 0.29 1.9 Protoplasts-SecreTed protein; the gene product was detected among the proteins secreted by regenerating protoplasts
YJL208C NUC1 0.29 1.2 mitochondrial nuclease
YJL104W MIA1 0.29 1.5 Hypothetical ORF
YDR305C HNT2 0.29 0.9 "Fhit homolog, member of the histidine triad superfamily of nucleotide binding-proteins"
YOL043C NTG2 0.29 1.3 Endonuclease III-like glycosylase
YJR055W HIT1 0.29 1.1 Protein required for growth at high temperature
YNL320W 0.29 1.2
YLR203C MSS51 0.29 0.9 Protein required for the maturation and translation of COX1 mRNA
YDL201W TRM8 0.29 1.0 Transfer RNA methyltransferase
YKL150W MCR1 0.29 1.5 C NADH-cytochrome b5 reductase
YNR003C RPC34 0.29 1.2 34-kDa subunit of RNA polymerase III (C)
YGR192C TDH3 0.29 2.0 Glyceraldehyde-3-phosphate dehydrogenase 3
YOL158C ENB1 0.29 3.1 S Siderophore transporter for enterobactin; AFT1 regulon
YBR025C 0.29 0.8
YGR008C STF2 0.29 2.1 ATPase stabilizing factor
YCL001W RER1 0.29 1.4 "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi, where it may function in returning membrane proteins to the ER"
YNL290W RFC3 0.29 2.2 RFC is a DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA
YNR016C ACC1 0.29 1.5 C acetyl-CoA carboxylase
YPL198W RPL7B 0.29 1.2 Homolog of mammalian ribosomal protein L7 and E. coli L30
YDR179C CSN9 0.29 2.4 C Cop9 Signalosome(CSN)
YLR231C BNA5 0.29 1.2 S Biosynthesis of Nicotinic Acid
YPL088W 0.29 2.5
YNR062C 0.29 1.5
YHR054C 0.29 1.0
YGL170C SPO74 0.29 1.8 Sporulation
YLL005C SPO75 0.29 1.9 Sporulation
YLR109W AHP1 0.29 3.2 thioredoxin peroxidase
YER054C GIP2 0.29 1.8 "Glc7-interacting protein; shares homology with PIG2; contains conserved 25 residue motif, called the GVNK motif, also found in GAC1, PIG1, PIG2, and RGI, the mammalian type 1 phosphatase targeting subunit."
YDL022W GPD1 0.29 2.2 glycerol-3-phosphate dehydrogenase
YMR130W 0.29 1.0
YGR016W 0.29 1.0
YJR024C 0.29 0.9
YEL017C-A PMP2 0.29 3.4 May regulate plasma membrane H(+)-ATPase; nearly identical to PMP1
YOR388C FDH1 0.29 1.8 Protein with similarity to formate dehydrogenases
YOR332W VMA4 0.29 2.2 S vacuolar ATPase V1 domain subunit E (27 kDa)
YGR135W PRE9 0.29 1.0 proteasome component Y13
YDL047W SIT4 0.29 1.6 SIT4 suppress mutations in DBF2
YBR040W FIG1 0.29 3.8 "Factor-Induced Gene 1: expression is induced by the mating pheromones, a and alpha factor; required for efficient mating"
YJR152W DAL5 0.29 0.9 allantoate permease
YDL130W RPP1B 0.29 1.7 "Homology to rat P1, human P1, and E. coli L12eIIB"
YDR437W 0.29 1.6
YER135C 0.29 1.9
YNR012W URK1 0.29 1.9 converts ATP and uridine to ADP and UMP
YFL029C CAK1 0.29 0.9 binds and phosphorylates Cdc28p
YER073W ALD5 0.29 1.3 Utilizes NADP+ as the preferred coenzyme. Activated by K+.
YJL091C 0.29 2.7 S
YDL077C VAM6 0.29 1.6 Required for the vacuolar morphogenesis in yeast
YFR025C HIS2 0.29 1.0 Histidinolphosphatase
YJR009C TDH2 0.29 2.1 glyceraldehyde 3-phosphate dehydrogenase
YCR102C 0.29 1.5
YNL107W YAF9 0.29 0.9 Yeast homolog of the human leukemogenic protein AF9; member of a yeast chromatin modifying complex
YER062C HOR2 0.28 2.1 RHR2 (GPP1) encodes another DL-glycerol-3-phosphatase
YPR203W 0.28 5.3 Z S
YHR024C MAS2 0.28 1.0 53 kDa subunit of the mitochondrial processing protease
YBR087W RFC5 0.28 2.2 S RFC is a multisubunit DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA
YMR088C 0.28 1.3
YIL167W 0.28 4.0 S C
YJL060W BNA3 0.28 3.2 S Biosynthesis of Nicotinic Acid
YNL274C 0.28 2.7
YPL041C 0.28 1.9
YLR270W DCS1 0.28 2.6 trehalase-associated protein; hydrolase in the HIT superfamily.
YLR420W URA4 0.28 1.2 Third step in pyrimidine biosynthesis pathway
YCR092C MSH3 0.28 0.8 "acts in mismatch repair in mitosis and meiosis but to a lesser extent than MSH2, required for microsatellite stability"
YDL104C QRI7 0.28 1.6 similar to H.influenzae sialoglycoprotease
YLR224W 0.28 1.1
YCL037C SRO9 0.28 1.7 C Associates with translating ribosomes; may function in the cytoplasm to modulate mRNA translation; may be involved in organization of actin filaments
YKL141W SDH3 0.28 1.0 "Yeast succinate dehydrogenase (SDH) is a tetramer of non-equivalent subunits--Sdh1p, Sdh2p, Sdh3p, Sdh4p--that couples the oxidation of succinate to the transfer of electrons to ubiquinone."
YBL050W SEC17 0.28 1.2 peripheral membrane protein required for vesicular transport between ER and Golgi
similar to alpha-SNAP
part of cis-SNARE complex
required for 'priming' step in homotypic vacuole fusion
YBR052C 0.28 3.5 C
YDL059C RAD59 0.28 1.0 Involved in mitotic recombination
YOR287C 0.28 1.9
YKL157W APE2 0.28 1.6 "Removal of intron fused YKL158W and YKL157W (Davis et al.(2000) NAR 28:1700-6)."
YPL028W ERG10 0.28 0.9 induced under stress conditions
YPR166C MRP2 0.28 1.0 14 kDa mitochondrial ribosomal protein; homologous to E. coli S14 protein
YMR009W 0.28 1.4
YMR060C TOM37 0.28 1.2 Translocase of the Outer Mitochondrial membrane
YMR209C 0.28 0.8
YLR180W SAM1 0.28 3.0 Z S S-adenosylmethionine synthetase
YDL178W DLD2 0.28 1.1 "D-lactate dehydrogenase, located in mitochondrial matrix"
YBR004C 0.28 1.4
YDR258C HSP78 0.28 3.0 Similar to E. coli ClpB protein; involved in folding of some mitochondrial proteins
YIR024C GIF1 0.28 1.0 G1 Factor needed for normal G1 phase
YDR367W 0.28 1.6
YPR127W 0.28 1.6
YOR258W HNT3 0.28 2.0 S "histidine triad superfamily, third branch"
YGL111W NSA1 0.28 1.6 Nop seven associated
YGR256W GND2 0.28 1.9 "6-phosphogluconate dehydrogenase, decarboxylating; converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2"
YPL082C MOT1 0.28 1.3 involved in TBP (TATA-binding protein) regulation
YGR075C PRP38 0.28 0.9 RNA splicing factor
YER145C FTR1 0.28 2.9 S "high-affinity iron transporter, primarily expressed under oxygenated conditions."
YER051W 0.28 0.9
YBL108W 0.28 2.1
YKR105C 0.28 1.5
YKL144C RPC25 0.28 0.8 Subunit of RNA polymerase III
YDL006W PTC1 0.28 1.3 serine-threonine protein phosphatase
YAL062W GDH3 0.28 2.1 Involved in glutamate biosynthesis
YER074W RPS24A 0.28 1.0 Homology to rat S24
YIL069C RPS24B 0.28 1.0 Homology to rat S24
YGL076C RPL7A 0.28 0.8 Homology to rat L7 and E. coli L30
YOR375C GDH1 0.28 1.4 NADP-specific glutamate dehydrogenase
YKL026C GPX1 0.28 1.6 Glutathione peroxidase paralogue
YLR211C 0.28 1.3
YIL157C 0.28 1.5
YPL071C 0.28 1.4
YOR365C 0.28 0.8
YLR186W EMG1 0.28 0.9 Essential for Mitotic Growth
YMR175W SIP18 0.28 1.1 Salt-Induced Protein
YHL014C YLF2 0.28 0.9 Protein with weak similarity to B. subtilis GTP-binding protein and to human glycogen phosphorylases
YLR011W LOT6 0.28 0.9 LOw Temperature responsive
YKL114C APN1 0.28 1.2 major apurinic/apyrimidinic endonuclease/3'-repair diesterase
YIL015C-A 0.28 2.7
YBR183W YPC1 0.28 1.6 Yeast Phyto-ceramidase
YPR068C HOS1 0.28 0.9 "Protein with similarity to Hda1p, Rpd3p, Hos2p, and Hos3p"
YIL008W URM1 0.28 1.1 ubiquitin-like protein
YOR077W RTS2 0.28 1.7 similar to mouse KIN7 protein
YGR210C 0.28 1.2
YHR089C GAR1 0.28 1.1 small nucleolar RNP proteins
YNL044W YIP3 0.28 1.8 Interacts with YPT proteins
YKL216W URA1 0.28 0.9 The enzyme catalyzes the conversion of dihydroorotic acid to orotic acid
YHL041W 0.28 1.8
YOR185C GSP2 0.28 1.8 "maintenance of nuclear organization; homologous to mammalian Ran, a small nuclear GTPase of the ras superfamily"
YIR042C 0.28 2.2
YGR020C VMA7 0.28 1.3 vacuolar H-ATPase 14 kDa subunit (subunit F) of the catalytic (V1) sector
YGL106W MLC1 0.28 1.4 may stabilize Myo2p by binding to the neck region
YMR282C AEP2 0.28 1.9 Required for the translation of OLI1 mRNA.
YMR254C 0.28 3.0 S C
YBR077C 0.28 1.3
YCR073C SSK22 0.28 1.4 C "functionally redundant with, and homologous to, SSK2"
YHR174W ENO2 0.27 1.6 enolase
YLR459W CDC91 0.27 2.1 member of major facilitator superfamily
YDL174C DLD1 0.27 1.5 mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase
YKL094W YJU3 0.27 1.9 Product of gene unknown
YLR012C 0.27 1.1
YOR224C RPB8 0.27 1.7 "16-kDa RNA polymerase subunit (common to polymerases I, II and III)"
YKL214C YRA2 0.27 0.9 Yeast RNA Annealing protein
YGR098C ESP1 0.27 2.1 Esp1 promotes sister chromatid separation by mediating dissociation from the chromatin of the cohesin Scc1. The anaphase-promoting complex promotes anaphase by mediating destruction of Pds1 which binds to Esp1 and inhibits its activity
YLR236C 0.27 3.8 S C
YPR139C VPS66 0.27 1.3
YPR129W SCD6 0.27 0.9 multicopy suppressor of clathrin deficiency
YAR068W 0.27 1.7
YLL051C FRE6 0.27 2.4 similar to FRE2
YDL086W 0.27 1.7
YNR032W PPG1 0.27 1.0 Serine/threonine protein phosphatase involved in glycogen accumulation
YNR064C 0.27 0.8
YDR494W RSM28 0.27 2.1 Ribosomal Small subunit Mitochondria
YDR493W 0.27 2.6 S C
YKL106W AAT1 0.27 1.0 "aspartate aminotransferase, mitochondrial"
YER147C SCC4 0.27 1.5 a major role for the Scc2p/Scc4p complex appears to be to facilitate the loading of cohesin complexes onto chromosomes.
YGR102C 0.27 0.8
YMR257C PET111 0.27 1.6 translational activator of cytochrome c oxidase subunit II
YDL219W DTD1 0.27 1.7 D-Tyr-tRNA(Tyr) deacylase
YDL205C HEM3 0.27 1.3 catalyzes the third step in heme biosynthesis
YDR473C PRP3 0.27 0.9 snRNP from U4/U6 and U5 snRNPs
YOR236W DFR1 0.27 0.8 dihydrofolate reductase
YIR005W IST3 0.27 1.3 U2 snRNP associated protein
YDR020C 0.27 2.2
YMR041C 0.27 1.0
YMR047C NUP116 0.27 1.0 Involved in nucleocytoplasmic transport; may be required for biogenesis of tRNA
YBR220C 0.27 1.2
YHR128W FUR1 0.27 0.9 Regulation of the pyrimidine salvage pathway
YMR096W SNZ1 0.27 2.0 Snooze: stationary phase-induced gene family; involved in cellular response to nutrient limitation and growth arrest
YDR465C RMT2 0.27 1.6 Protein Arginine Methyltransferase; R = arginine; MT = methyltransferase
YHR029C 0.27 2.0 S
YDR500C RPL37B 0.27 0.9 Homology to rat L37
YJR118C ILM1 0.27 1.4 Product of gene unknown
YHR116W 0.27 1.1
YGL254W FZF1 0.27 1.1 involved in sulfite resistance
YIL090W 0.27 1.7
YMR020W FMS1 0.27 1.7 "Multicopy suppressor of fenpropimorph resistance (fen2 mutant), shows similarity to Candida albicans corticosteroid-binding protein CBP1"
YLR126C 0.27 2.5 C
YGL154C LYS5 0.27 0.8 Responsible for the posttranslational conversion of the alpha-aminoadipate semialdehyde reductase Lys2 from the inactive apo-form into the catalytically active holo-form.
YGR209C TRX2 0.27 1.2 thioredoxin
YBL045C COR1 0.27 0.8 44 kDa core protein of yeast coenzyme QH2 cytochrome c reductase
YLR381W CTF3 0.27 2.9 C kinetochore-related protein
YPR110C RPC40 0.27 1.0 RNA polymerase III (C) subunit
YML022W APT1 0.27 1.2 Adenine phosphoribosyltransferase
YFL018C LPD1 0.27 0.9 an FAD flavoprotein which contains a pair of redox-active cysteines involved in the transfer of reducing equivalents from the FAD cofactor to the substrate
YLR204W QRI5 0.27 0.9 Product of gene unknown
YOR267C HRK1 0.27 0.9 Hygromycin Resistance Kinase
YDL014W NOP1 0.27 1.1 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
YPL234C TFP3 0.27 1.3 vacuolar ATPase V0 domain subunit c' (17 kDa)
YBR162W-A YSY6 0.27 1.3 Protein that participates in secretory pathway
YLR389C STE23 0.27 1.3 involved in a-factor processing
YML003W 0.27 1.2
YML028W TSA1 0.27 1.0 antioxidant enzyme that provides protection against oxidation systems capable of generating reactive oxygen and sulfur species
YKL054C DEF1 0.27 0.9 RNA polymerase II DEgradation Factor 1
YMR259C 0.27 1.2
YDL090C RAM1 0.27 1.2 essential for processing of ras proteins
YHL024W RIM4 0.27 0.9 Regulator of IMe2 expression
YDR236C FMN1 0.27 1.8 Riboflavin kinase
YPR153W 0.27 2.7
YPL067C 0.27 1.1
YGR119C NUP57 0.27 1.6 "Forms complex with Nsp1p, Nup49p, and Nic96p at nuclear pore; this complex participates in nucleocytoplasmic transport; in vitro, Nsp1p, Nup49p and Nup57p form a 1:1:1 stoichiometric complex to which Nic96p can also bind"
YAL015C NTG1 0.27 2.1 endonuclase III like glycosylase involved in DNA repair
YMR035W IMP2 0.27 1.1 Inner membrane protease (mitochondrial protein)
YFL016C MDJ1 0.27 1.9 involved in protection against heat-induced protein aggregation but not necessary for protein import into the mitochondrion
YOL002C 0.27 2.3
YDR086C SSS1 0.27 1.6 involved in transfer of secretory precursors through the endoplasmic reticulum membrane
YIL094C LYS12 0.26 2.0 S "homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate."
YDR007W TRP1 0.26 0.9 "Note that the sequence of TRP1 from strain S228C, which is the sequence stored in SGD, contains an ochre mutation at codon 67."
YDR250C 0.26 2.0
YBR221C PDB1 0.26 0.8 beta subunit of pyruvate dehydrogenase (E1 beta)
YEL008W 0.26 1.6
YLR163C MAS1 0.26 1.3 mitochondrial processing protease subunit
YOR067C ALG8 0.26 1.0 adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein
YNL093W YPT53 0.26 1.5 Involved in vacuolar protein sorting and endocytosis
YNL090W RHO2 0.26 1.1 Gtp-binding protein of the rho subfamily of ras-like proteins
YOR202W HIS3 0.26 1.4 imidazoleglycerol-phosphate dehydratase
YGR285C ZUO1 0.26 1.1 Zuotin has region of DnaJ homology
YEL072W RMD6 0.26 1.3 Required for Meiotic nuclear Division
YDR019C GCV1 0.26 2.2 Required for metabolizing glycine as a nitrogen source
YML091C RPM2 0.26 1.7 C involved in processing of mitochondrial precursor tRNAs and protein import
YKL066W 0.26 3.9 S C
YDR531W 0.26 1.2
YMR147W 0.26 2.4
YOL107W 0.26 1.2
YER080W 0.26 1.2
YLR172C DPH5 0.26 0.9 diphthamide biosynthesis
YPR069C SPE3 0.26 0.9 biosynthesis of spermidine
YLR251W SYM1 0.26 1.8 stress-induced yeast MPV17 homolog
YDL124W 0.26 2.5 C
YLR244C MAP1 0.26 1.0 methionine aminopeptidase
YHR046C INM1 0.26 1.1 inositol monophosphatase
YJR107W 0.26 0.9
YGL104C VPS73 0.26 1.4
YGL010W 0.26 1.5
YNL037C IDH1 0.26 3.2 S alpha-4-beta-4 subunit of mitochondrial isocitrate dehydrogenase 1
YOR207C RET1 0.26 2.2 second-largest subunit of RNA polymerase III
YJL001W PRE3 0.26 1.3 "Responsible for the postacidic activity of the yeast 20S proteasome, and necessary for hydrolysis of peptidylglutamyl-peptide."
YBL082C RHK1 0.26 2.8 Z "Resistance to Hansenula Killer 1, hypothetical F-458 protein"
YCL068C 0.26 1.2
YIL103W 0.26 1.7
YGR015C 0.26 1.8
YBR145W ADH5 0.26 0.9 alcohol dehydrogenase isoenzyme V
YPL097W MSY1 0.26 1.8 Tyrosyl-tRNA synthetase
YCR009C RVS161 0.26 1.8 "Protein required for viability after N, C, or S starvation. The BAR adaptor proteins encoded by RVS167 and RVS161 form a complex that regulates actin, endocytosis, and viability following starvation or osmotic stress."
YBL080C PET112 0.26 2.0 "May serve important general function in mitochondrial gene expression, probably in translation; required for translation of COX2 mRNA"
YHR099W TRA1 0.26 1.1 TRA1 is the homolog of the human protein TRRAP which we have isolated as an essential cofactor of c-Myc.
YOR252W 0.26 0.9
YIL007C 0.26 1.5
YNL333W SNZ2 0.26 2.7 Snooze: stationary phase-induced gene family
YMR064W AEP1 0.26 1.3 Requried for the translation of OLI1 mRNA.
YPL033C 0.26 1.2
YJL205C-A NCE101 0.26 2.3 involved in secretion of proteins that lack classical secretory signal sequences
YEL007W 0.26 0.8
YLR293C GSP1 0.26 1.0 "maintenance of nuclear organization; homologous to mammalian Ran, a small nuclear GTPase of the ras superfamily"
YFR047C BNA6 0.26 1.8 Biosynthesis of Nicotinic Acid
YGL236C MTO1 0.26 1.9 Mitochondrial Translation Optimization; Strong similarity to E. coli GidA
YBR248C HIS7 0.26 1.1 "glutamine amidotransferase:cyclase, also called imidazole glycerol phosphate synthase"
YGR271W SLH1 0.26 1.5 SKI2-like helicase
YMR132C 0.26 1.5
YOL096C COQ3 0.26 1.3 "3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase"
YJR066W TOR1 0.26 1.1 Involved in cell cycle signaling and meiosis
YJR094W-A RPL43B 0.26 1.3 Homology to human L37a
YGL230C 0.26 1.8
YOR113W AZF1 0.26 1.2 "probable transcription factor, asparagine-rich zinc-finger protein, suppressor of mutation in the nuclear gene for the core subunit of mitochondrial RNA polymerase"
YPR043W RPL43A 0.26 1.5 Homology to human L37a
YMR117C SPC24 0.26 1.7 Spindle Pole Component of molecular weight 24kDa
YLR405W 0.26 1.6
YBL018C POP8 0.26 0.9 Processing Of Precursors - a group of proteins that appear to be components of both RNase P and RNase MRP
YOR149C SMP3 0.26 1.1 "Involved in glycosyl phosphatidyl inositol synthesis; most likely an alpha 1,2 mannosyltransferase utilized for addition of the fourth, side-branching mannose onto the GPI core structure."
YNL063W 0.26 1.9
YEL026W SNU13 0.26 1.3 "part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); RNA binding protein (putative), similar to Nhp2p"
YEL046C GLY1 0.26 1.5 L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine
YLR170C APS1 0.26 1.9 Involved in a subset of clathrin functions at the Golgi
YER128W 0.26 1.0
YAL008W FUN14 0.26 1.9 Product of gene unknown
YDR404C RPB7 0.26 1.8 dissociable subunit of RNA polymerase II
YJR117W STE24 0.25 1.1 zinc metallo-protease that catalyzes the first step of N-terminal processing of the yeast a-factor precursor
YPR001W CIT3 0.25 1.3 Mitochondrial isoform of citrate synthase
YDR319C 0.25 1.2
YDR286C 0.25 1.3
YLR414C 0.25 1.2
YFL059W SNZ3 0.25 3.2 Snooze: stationary phase-induced gene family
YMR090W 0.25 2.9 C
YER107C GLE2 0.25 0.9 "Nuclear pore protein required for poly(A)+ RNA export, has beta-transducin (WD-40) repeats"
YER039C HVG1 0.25 1.4 Homologous to VRG4
YLR284C ECI1 0.25 0.8 enoyl-CoA isomerase
YHR051W COX6 0.25 2.1 subunit VI of cytochrome c oxidase
YML120C NDI1 0.25 2.3 S NADH dehydrogenase (ubiquinone)
YHL044W 0.25 1.6
YLR323C CWC24 0.25 0.9 Complexed with Cef1p
YHR043C DOG2 0.25 1.6 2-deoxyglucose-6-phosphate phosphatase
YOR126C IAH1 0.25 2.8 S isoamyl acetate-hydrolyzing esterase
YGL181W GTS1 0.25 1.1 Putative zinc-finger transcription factor
YDR248C 0.25 2.1
YJL097W 0.25 1.5
YKL095W YJU2 0.25 1.5 Product of gene unknown
YKL014C 0.25 1.7
YMR139W RIM11 0.25 0.9 "Required for Ime1p phosphorylation, association of the Ime1p-Ume6p meiotic activator, early meiotic gene expression, and sporulation"
YOR159C SME1 0.25 2.0 "Required for pre-mRNA splicing, cap modification and U1, U2, U4 and U5 snRNA stability"
YPR201W ARR3 0.25 2.4 Putative membrane protein involved in arsenite transport
YDL044C MTF2 0.25 1.3 Necessary for the stability and/or processing of some large mitochondrial transcripts
YML014W 0.25 0.9
YLR066W SPC3 0.25 1.1 signal peptidase subunit
YKR070W 0.25 1.1
YLR150W STM1 0.25 0.9 Multicopy suppressor of tom1 and pop2 mutations. Genetically interacts with CDC13 to maintain telomere structure.
YBR256C RIB5 0.25 1.0 S Riboflavin biosynthesis
YHR135C YCK1 0.25 2.9 S membrane-bound casein kinase I homolog
YDL088C ASM4 0.25 1.1 Suppressor of thermosensitive mutations in the DNA polymerase delta gene
YKR080W MTD1 0.25 1.8 "NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase"
YBL089W 0.25 1.1
YLR208W SEC13 0.25 1.0 cytoplasmic protein involved in release of transport vesicles from the ER
YNL007C SIS1 0.25 1.6 HSP40 family chaperone
YFL064C 0.25 4.6 Z S
YHR083W 0.25 0.8
YJR144W MGM101 0.25 1.9 Involved in mitochondrial genome maintenance
YML005W 0.25 0.9
YDR503C LPP1 0.25 4.5 Z S Lipid phosphate phosphatase
YOR091W 0.25 1.0
YOR351C MEK1 0.25 1.1 "Disp. for chr. pairing & chr. condensation seen by in situ hybrid. Required for full double strand breaks, normal length synaptonemal complexes, meiotic recomb. & spore viability. mek1 is rescued by spo13 & in early recomb. function"
YIL139C REV7 0.25 1.5 Protein required for mutagenesis by physical and chemical agents
YBR046C ZTA1 0.25 1.3 "Zeta-crystallin homolog, has similarity to E. coli quinone oxidoreductase and human zeta-crystallin which has quinone oxidoreductase activity"
YOR131C 0.25 1.6
YHR086W NAM8 0.25 4.4 S C "May be non-essent. part of mito. splicing. Assoc. with spliceosomal snRNPs. Disp. for mitosis & premeiotic DNA synth. Required in meiosis-specific splicing of MER2 & MER3, double strand breaks, synaptonemal complexes"
YIL165C 0.25 1.7
YMR256C COX7 0.25 1.3 C subunit VII of cytochrome c oxidase
YFL038C YPT1 0.25 1.0 involved in the secretion pathway at the ER-to-Golgi step; required for sporulation
YCL069W 0.25 1.3
YOL146W 0.25 1.8
YOR184W SER1 0.25 1.6 phosphoserine transaminase
YJL030W MAD2 0.25 0.8 spindle checkpoint complex subunit
YFL006W 0.25 2.2 S
YIL035C CKA1 0.25 1.2 alpha subunit of protein kinase CK2
YDR087C RRP1 0.25 1.3 involved in processing rRNA precursor species to mature rRNAs
YOR262W 0.24 1.2
YNL032W SIW14 0.24 1.8 Synthetic interaction with Whi2
YMR145C NDE1 0.24 3.7 S Hypothetical ORF
YMR072W ABF2 0.24 2.4 "HMG-1 homolog, mitochondrial"
YOL140W ARG8 0.24 0.8 Acetylornithine aminotransferase
YBR213W MET8 0.24 1.0 Protein involved in the expression of PAPS reductase and sulfite reductase. Also executes last 2 steps in the biosynthesis of sirohaem.
YGL049C TIF4632 0.24 0.9 also called eIF4 (eIF-4) gamma
YPL244C HUT1 0.24 1.1 similar to UDP-galactose transporter
YDL085W NDE2 0.24 1.6 Hypothetical ORF
YER037W PHM8 0.24 1.3 involved in phosphate metabolism
YIL042C 0.24 0.8
YNL264C PDR17 0.24 0.9 involved in pleiotropic drug resistance by controlling lipids in various cellular compartments; putative phosphatidylinositol transfer protein.
YMR313C 0.24 1.5
YCR082W 0.24 1.6
YFL056C AAD6 0.24 1.4 high degree of similarity with the AAD of P. chrysosporium
YNL280C ERG24 0.24 1.3 sterol C-14 reductase
YLR124W 0.24 3.4
YNR004W 0.24 2.5
YJR101W RSM26 0.24 0.9 mitochondrial ribosome small subunit component
YDL021W GPM2 0.24 1.3 Similar to GPM1 (phosphoglycerate mutase); converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis
YDR050C TPI1 0.24 1.9 induced under stress conditions
YAL036C FUN11 0.24 0.8 Function Unknown Now; similar to Xenopus GTP-binding protein DRG
YFR042W 0.24 1.7
YGR227W DIE2 0.24 0.9 De-repression of ITR1 Expression
YGL047W 0.24 1.0
YLR229C CDC42 0.24 1.5 cell division cycle blocked at 36 degree C
YML048W GSF2 0.24 1.1 Glucose Signaling Factor
YKL013C ARC19 0.24 1.2 Arp complex subunit
YOR089C VPS21 0.24 1.1 Rab5-like GTPase involved in vacuolar protein sorting and endocytosis post vesicle internalization; geranylgeranylated; geranylgeranylation required for membrane association
YIL084C SDS3 0.24 1.1 Suppressor of Defective Silencing 3
Functions are similar to those of SIN3 and RPD3
YMR087W 0.24 1.3
YLR301W 0.24 1.0
YJR013W 0.24 1.0
YOR137C SIA1 0.24 2.9 Suppressor of eIF5A
YGR275W RTT102 0.24 1.8 Regulator of Ty1 Transposition
YJL052W TDH1 0.24 2.2 Glyceraldehyde-3-phosphate dehydrogenase 1
YDR453C TSA2 0.24 2.2 thioredoxin peroxidase
YMR322C 0.24 1.5
YGL084C GUP1 0.24 1.6 Involved in active glycerol uptake
YOL086C ADH1 0.24 2.1 Alcohol dehydrogenase
YLR360W VPS38 0.24 1.1 involved in vacuolar protein targeting
YLR447C VMA6 0.24 1.2 vacuolar ATPase V0 domain subunit d (36 kDa)
YGR206W 0.24 1.4
YBL081W 0.24 0.9
YLR029C RPL15A 0.24 1.9 Homology to rat L15
YBR191W RPL21A 0.24 2.6 Homology to rat L21
YDR414C ERD1 0.24 1.1 Protein required for retention of luminal ER proteins
YDR267C 0.24 1.0
YCL035C GRX1 0.24 1.3 Glutaredoxin
YLL042C APG10 0.24 1.2 Involved in autophagy; protein-conjugating enzyme involved in the Apg12p-Apg5p conjugation pathway
YOR111W 0.24 1.5
YKL069W 0.24 3.5 Z S C
YJR062C NTA1 0.24 1.7 "Removes amide group from N-terminal asparagine and glutamine, to generate aspartate and glutamate, which are destabilizing terminal residues"
YMR084W 0.24 2.0
YOR086C 0.24 1.0
YEL025C SRI1 0.23 2.6 S Swi/SNF and RSC interacting protein 1
YPL218W SAR1 0.23 1.6 "Secretion-Associated, Ras-related. Component of COPII coat of vesicles; required for ER to Golgi protein transport"
YHR183W GND1 0.23 1.6 "6-phosphogluconate dehydrogenase, decarboxylating; converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2"
YLR318W EST2 0.23 1.5 ever shorter telomeres
YIL064W 0.23 0.8
YOL042W NGL1 0.23 1.4 "DNase/RNase (putative); CCR4 C-terminal homolog, homology to drosophila Angel gene"
YJL126W NIT2 0.23 0.9 "Nit protein, nitrilase superfamily member"
YIR037W HYR1 0.23 1.7 Hydroperoxide resistance conferring gene
YML131W 0.23 2.6
YBR201W DER1 0.23 1.5 Degradation in the Endoplasmic Reticulum
YIL168W SDL1 0.23 3.1 S L-serine dehydratase
YDR136C VPS61 0.23 2.7 Vacuolar Protein Sorting
YBR136W MEC1 0.23 2.0 "Required for mitotic growth, DNA repair and mitotic recombination, regulates phosporylation of Rad53p, required for dmc1 arrest and meiotic recombination"
YIL082W 0.23 2.3
YLL014W 0.23 1.7
YKR057W RPS21A 0.23 1.4 Homology to rat S21
YEL003W GIM4 0.23 0.9 "Prefoldin subunit 2; putative homolog of subunit 2 of bovine prefoldin, a chaperone comprised of six subunits"
YDL081C RPP1A 0.23 2.7 "Homology to rat P1, human P1, and E.coli L12eIIA"
YJR105W ADO1 0.23 0.8 adenosine kinase
YDR332W 0.23 1.0
YGL117W 0.23 1.7
YNL070W TOM7 0.23 0.9 Involved in mitochondrial protein import
YKL207W 0.23 1.0
YJL145W SFH5 0.23 1.4 putative phosphatidylinositol transfer protein
YPL147W PXA1 0.23 1.7 Pxa1p and Pxa2p appear to be subunits of a peroxisomal ATP-binding cassette transporter necessary for transport of long-chain fatty acids into peroxisomes
YDR344C 0.23 1.2
YML087C 0.23 1.7
YER002W NOP16 0.23 2.0 Nucleolar protein 16
YNL129W 0.23 1.3
YGR244C LSC2 0.23 1.3 "beta subunit of succinyl-CoA ligase (synthetase; ATP-forming), a mitochondrial enzyme of the TCA cycle"
YPL275W 0.23 1.4
YDR010C 0.23 1.9
YBR171W SEC66 0.23 1.6 "glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins"
YMR202W ERG2 0.23 2.5 S sterol biosynthesis
YCR032W BPH1 0.23 1.5 beige protein homologue 1
YOR040W GLO4 0.23 1.4 Mitochondrial glyoxylase-II
YPL273W SAM4 0.23 1.0 AdoMet-homocysteine methyltransferase
YCR001W 0.23 1.3
YKR101W SIR1 0.23 1.4 repressor of silent mating loci
YJR074W MOG1 0.23 1.3 Required for nuclear-protein import
YLR240W VPS34 0.23 1.7 phosphatidylinositol 3-kinase
YPR154W PIN3 0.23 0.8 [PSI+] induction
YNL220W ADE12 0.23 1.3 adenylosuccinate synthetase
YJR133W XPT1 0.23 1.2 Xanthine Phosphoribosyl Transferase
YHL006C SHU1 0.23 0.9 suppressor of HU sensitivity involved in recombination
YGL226W 0.23 1.8
YCL065W 0.23 2.3 S
YJL183W MNN11 0.23 2.9 "member of a cis Golgi complex that is involved in mannan synthesis, other complex members include Mnn10p, Hoc1p, Anp1p, Mnn9p"
YLR376C PSY3 0.23 2.1 C Platinum Sensitivity
YMR121C RPL15B 0.23 1.2 Homology to rat L15
YDR013W 0.23 1.8 C
YDL061C RPS29B 0.23 2.4 Homology to rat S29
YHR008C SOD2 0.23 1.7 Manganese-containing superoxide dismutase
YKL138C MRPL31 0.23 1.0 15.5 kDa mitochondrial ribosomal protein YmL31
YHR104W GRE3 0.23 3.7 Induced by osmotic stress; similar to xylose reductase from other fungi. Reduces xylose to xylitol.
YMR207C HFA1 0.23 1.0 Similar to acetyl-coenzyme A carboxylase
YOR157C PUP1 0.23 1.1 putative proteasome subunit
YKL040C NFU1 0.23 1.0 Nifu-like protein
YLR048W RPS0B 0.23 1.7 Homology to rat Sa; closely related to mammalian p40/laminin receptor precursors (LRPs); required for translation and contributes to the assembly and/or stability of the 40S ribosomal subunit
YDR471W RPL27B 0.23 1.2 Homology to mammalian L27
YLL054C 0.23 1.2
YPL080C 0.23 1.1
YNR077C 0.23 1.2
YML055W SPC2 0.23 1.0 "subunit of signal peptidase complex, homologous to mammalian protein SPC25"
YOR298W 0.23 3.8 S
YGR268C 0.23 0.9
YDR315C IPK1 0.23 1.1 inositol polyphosphate kinase
YOL094C RFC4 0.23 2.2 S RFC is a DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA
YNR057C BIO4 0.23 1.3 dethiobiotin synthetase
YLR316C TAD3 0.23 1.3 tRNA-specific adenosine-34 deaminase subunit Tad3p
YLR306W UBC12 0.23 1.5 "Required for conjugation of RUB1 (ubiquitin-like protein) to other proteins. Collaborates with ULA1/UBA3 RUB1-activating enzyme. Related to ubiquitin-conjugating enzymes (UBC1-8, UBC10-11, UBC13). Related to SMT3-conjugating enzyme UBC9"
YGR154C 0.22 1.1
YGR280C PXR1 0.22 1.6 PinX1-Related gene
G-patch NucleOlar protein
YPL079W RPL21B 0.22 1.3 Homology to rat L21
YOR021C 0.22 1.3
YNL231C PDR16 0.22 2.7 S involved in pleiotropic drug resistance by controlling lipids in various cellular compartments; positively regulated by PDR1; putative phosphatidylinositol transfer protein.
YBL038W MRPL16 0.22 0.9 Mitochondrial ribosomal protein MRPL16
YML107C 0.22 1.8
YGR031W 0.22 1.2
YCL056C 0.22 1.0
YIL111W COX5B 0.22 1.3 Cytochrome-c oxidase chain Vb
YNL196C SLZ1 0.22 1.1 "sporulation-specific protein with a leucine zipper motif, regulated by the transcription factor Ume6 and expressed early in meiosis"
YCR040W MATALPHA1 0.22 2.7 Z S transcription factor involved in the regulation of alpha-specific genes
YCL066W HMLALPHA1 0.22 2.0 S transcription factor involved in the regulation of alpha-specific genes
YLR378C SEC61 0.22 1.6 membrane component of ER protein translocation apparatus
YPR096C 0.22 1.7
YPL002C SNF8 0.22 0.9 appears to be functionally related to SNF7
YPR028W YOP1 0.22 3.1 Ypt Interacting Protein
YJL072C 0.22 2.3 S
YMR283C RIT1 0.22 1.4 Modifies initiator methionine tRNA to distinguish it from elongator methionine tRNA
YNL260C 0.22 1.1
YJL173C RFA3 0.22 4.4 K Z S C "RFA1, RFA2, and RFA3 make up RPA"
YBR037C SCO1 0.22 1.2 inner mitochondrial membrane protein
YKL067W YNK1 0.22 5.1 Z S C Nucleoside diphosphate kinase
YGL240W DOC1 0.22 1.5 Doc1p and Cdc26p are associated with the anaphase-promoting complex and are involved in the degradation of Clb2p
YIL027C KRE27 0.22 0.8 Killer toxin REsistant
YBR159W 0.22 1.8
YMR287C MSU1 0.22 2.3 Protein essential for mitochondrial biogenesis
YCR038C BUD5 0.22 1.8 GTP/GDP exchange factor for Rsr1 protein
YEL038W UTR4 0.22 1.2 Product of gene unknown
YHR010W RPL27A 0.22 1.6 Homology to mammalian L27
YPR054W SMK1 0.22 1.5 involved in sporulation
YFR043C 0.22 1.2
YMR097C MTG1 0.22 1.7 Hypothetical ORF
YIL020C HIS6 0.22 1.0 phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase
YGR232W NAS6 0.22 1.4 Interaction with the 19S regulatory particle of the 26S proteasome detected by coimmunoprecipitation.
YBR070C 0.22 5.6 Z S C
YGR243W 0.22 2.6
YKL152C GPM1 0.22 1.6 converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis
YBR153W RIB7 0.22 1.3 "Protein involved in the biosynthesis of riboflavin, second step in the riboflavin biosynthesis pathway"
YFR012W 0.22 1.5
YGL221C NIF3 0.22 0.8 similar to Listeria monocytogenes major sigma factor (rpoD gene product)
YJR050W ISY1 0.22 0.9 "Interacts with Syf1p, Prp39p and Ypl213wp. May play a role in mRNA splicing."
YLL062C MHT1 0.22 3.3 S C S-Methylmethionine Homocysteine methylTransferase
YMR225C MRPL44 0.22 1.7 Mitochondrial ribosomal protein MRPL44 (YmL44)
YML051W GAL80 0.22 1.2 inhibits transcription activation by Gal4p in hte absence of galactose
YAL029C MYO4 0.22 1.5 "Required for mother-specific HO expression, needed for the accumulation in daughter nuclei of Ash1p"
YJL006C CTK2 0.22 1.5 cyclin-related subunit of the kinase complex that phosphorylates the RPO21 CTD (carboxy-terminal domain); also called CTDK-I beta subunit
YBL095W 0.22 1.7
YPL257W 0.22 0.9
YML066C SMA2 0.22 2.3 S Spore Membrane Assembly
YHR016C YSC84 0.22 1.6 SH3 domain in C-terminus
YKL203C TOR2 0.22 1.8 "putative protein/phosphatidylinositol kinase involved in signaling activation of translation initiation, distribution of the actin cytoskeleton, and meiosis"
YJR058C APS2 0.22 1.5 Related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
YGR216C GPI1 0.22 1.4 "Participates in synthesis of N-acetylglucoaminylphosphatidylinositol, the first intermediate in synthesis of glycosylphosphatidylinositol (GPI) anchors"
YNL086W 0.22 1.2
YMR099C 0.22 1.6
YGR118W RPS23A 0.22 1.7 Homology to rat S23 and E. coli S12
YPR132W RPS23B 0.22 1.0 Homology to rat S23 and E. coli S12
YHR093W AHT1 0.22 0.9 the AHT1 DNA sequence is upstream of HXT4 and contains an HXT4 regulatory element which is a multicopy suppressor of glucose transport defects; probable non-functional ORF
YDR196C 0.21 1.4
YDL064W UBC9 0.21 1.9 Conjugates Smt3p to proteins
YOL149W DCP1 0.21 1.2 Decapping protein involved in mRNA degradation
YLR118C 0.21 1.1
YPR191W QCR2 0.21 2.2 40 kDa ubiquinol cytochrome-c reductase core protein 2
YBR160W CDC28 0.21 1.1 C Catalytic subunit of the main cell cycle cyclin-dependent kinase
YPR011C 0.21 1.2
YMR150C IMP1 0.21 1.3 Inner membrane protease (mitochondrial protein)
YPR004C 0.21 1.8
YNL281W HCH1 0.21 1.3 high copy Hsp90 supressor
YIR022W SEC11 0.21 1.1 signal peptidase subunit
YOR293W RPS10A 0.21 1.2 Homology to rat S10
YOR319W HSH49 0.21 1.9 Human SAP Homolog 49. A yeast homolog of a human spliceosome associated protein (SAP) called SAP 49.
YLR075W RPL10 0.21 1.3 "similar to members of the QM gene family, which is implicated in differentiation in other eukaryotes and tumorigenesis in humans; homology to rat L10; ubiquinol-cytochrome C reductase complex subunit VI requiring protein"
YOR278W HEM4 0.21 1.0 catalyzes the fourth step in the heme biosynthesis pathway
YOR095C RKI1 0.21 0.9 Ribose-5-phosphate ketol-isomerase
YDL135C RDI1 0.21 2.0 Rho GDP dissociation inhibitor with activity toward Rho1p
YOR289W 0.21 1.9
YPR182W SMX3 0.21 0.9 Sm or Sm-like snRNP protein
YPR082C DIB1 0.21 1.2 Homolog of S. pombe dim1+
YHR181W 0.21 1.1
YKL070W 0.21 2.0
YBL025W RRN10 0.21 1.7 subunit of UAF (upstream activation factor); involved in promoting high level transcription of rDNA
YDR515W SLF1 0.21 1.7 Associates with translating ribosomes; may function in cytoplasm to modulate mRNA translation; regulates the copper-dependent mineralization of copper sulfide complexes on cell surface in cells cultured in medium containing copper salts
YOR120W GCY1 0.21 1.9 "Galactose-induced transcript, product is homologous to mammalian aldo/keto reductases, as well as to gamma-crystallin, a vertebrate eye lens protein"
YDR047W HEM12 0.21 1.1 fifth enzyme in the heme biosynthetic pathway
YGL122C NAB2 0.21 1.1 nuclear polyadenylated RNA binding protein
YLR065C 0.21 0.9
YGR248W SOL4 0.21 2.4 similar to SOL3
YLR100W ERG27 0.21 2.1 S 3-keto sterol reductase
YPL129W TAF14 0.21 1.2 Protein required for actin cytoskeleton assembly or function
YKR030W MSG1 0.21 1.0 Multicopy suppressor of gea1-6
YGL187C COX4 0.21 2.6 subunit IV of cytochrome c oxidase
YLR050C 0.21 2.6 S C
YDR079W PET100 0.21 1.5 cytochrome c oxidase-specific assembly factor
YIL079C AIR1 0.21 1.6 arginine methyltransferase-interacting RING finger protein
YJR099W YUH1 0.21 0.8 ubiquitin hydrolase
YFL027C GYP8 0.21 2.1 GAP for Ypt protein
YOR061W CKA2 0.21 0.8 may have a role in regulation and/or execution of the eukaryotic cell cycle
YNL208W 0.21 2.1 S
YDL142C CRD1 0.21 1.7 Cardiolipin synthase
YGL101W 0.21 4.7 Z S C
YLL049W 0.21 1.5
YDR540C 0.21 2.3
YDR428C 0.21 1.2
YGR133W PEX4 0.21 1.0 Involved in peroxisome biogenesis
YNR017W MAS6 0.21 1.1 23 kDa mitochondrial inner membrane protein
YOR094W ARF3 0.21 0.9 GTP-binding ADP-ribosylation factor
YNL334C SNO2 0.21 1.7 "SNZ2 proximal ORF, stationary phase induced gene"
YPL040C ISM1 0.21 1.5 nuclear encoded mitochondrial isoleucyl-tRNA synthetase
YFL060C SNO3 0.21 3.0 S "SNZ3 proximal ORF, stationary phase induced gene family"
YNL255C GIS2 0.21 0.8 GIG3 suppressor
YER146W LSM5 0.21 1.4 Like Sm-E protein
YGR220C MRPL9 0.20 1.7 Mitochondrial ribosomal protein MRPL9 (YmL9) (E. coli L3) (human MRL3)
YGL088W 0.20 1.6
YDR377W ATP17 0.20 1.3 Subunit f of mitochondrial ATP synthase. Homologous to bovine subunit f.
YGR012W 0.20 1.5
YDR399W HPT1 0.20 1.6 enzyme involved in de novo purine biosynthesis
YOR130C ORT1 0.20 2.4 "Mitochondrial integral membrane protein, ornithine transporter"
YBR042C 0.20 1.3
YPL029W SUV3 0.20 0.8 putative ATP-dependent helicase
YBR084W MIS1 0.20 1.9 mitochondrial C1-tetrahydroflate synthase
YKL032C IXR1 0.20 2.8 Z C intrastrand crosslink recognition protein
YOL072W THP1 0.20 1.2
YMR281W GPI12 0.20 1.0 N-acetylglucosaminylphosphatidylinositol de-N-acetylase
YJL161W 0.20 1.3
YLR209C PNP1 0.20 2.7 S "purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides"
YDR529C QCR7 0.20 1.7 ubiquinol-cytochrome c oxidoreductase subunit 7 (14 kDa)
YPR020W ATP20 0.20 1.2 Protein associated with mitochondrial ATP Synthase; essential for dimeric state of ATP synthase
YLR064W 0.20 1.2
YFR050C PRE4 0.20 1.4 "B-type subunit of proteasome, euk. & archae. multicatalytic proteinase complex likelyinvolved in an ATP/ubiquitin-dependent nonlysosomal proteolytic pathway. eukary: the proteasome is composed of ~24 subunits forming a ring-shaped structure"
YJL218W 0.20 2.6
YNL153C GIM3 0.20 0.8 "Prefoldin subunit 4; putative homolog of subunit 4 of bovine prefoldin, a chaperone comprised of six subunits"
YPL060W LPE10 0.20 1.2 mitochondrial protein with homology to MRS2
YLR191W PEX13 0.20 0.9 "Pas20p may be the component of peroxisomal protein import machinery that binds Pex5p, the mobile receptor for type I peroxisomal targeting sequence (PTS1)-containing proteins"
YMR164C MSS11 0.20 1.3 Multicopy Suppressor of STA10 - 11
YIR001C SGN1 0.20 1.4 contains one RNA recognition (RRM) domain
YIL053W RHR2 0.20 1.8 DL-glycerol-3-phosphatase
YLR009W RLP24 0.20 1.1 Ribosomal Like Protein 24
YOR391C 0.20 3.5 S
YKL218C SRY1 0.20 2.5 Serine Racemase homolog in Yeast
YJR085C 0.20 1.5
YBR282W MRPL27 0.20 1.1 essential for mitochondrial function
YDL137W ARF2 0.20 0.9 ADP-ribosylation factor 2
YMR114C 0.20 1.1
YOL143C RIB4 0.20 1.0 catalyzes synthesis of immediate precursor to riboflavin
YCR063W BUD31 0.20 1.5
YKL192C ACP1 0.20 1.1 mitochondrial acyl carrier protein
YPR172W 0.20 1.3
YNL135C FPR1 0.20 1.4 FK506 binding protein; proline rotamase; rapamycin-binding protein
YJR112W NNF1 0.20 1.8 C Involved in nuclear function
YPL052W 0.20 1.3
YBR242W 0.19 3.1 Z S
YPR098C 0.19 1.2
YPL108W 0.19 1.7
YJR096W 0.19 1.2
YJL166W QCR8 0.19 2.3 Ubiquinol cytochrome-c reductase subunit 8 (11 kDa protein)
YPR165W RHO1 0.19 1.9 Gtp-binding protein of the rho subfamily of ras-like proteins
YIR038C GTT1 0.19 1.8 Glutathione Transferase
YPL280W 0.19 1.7
YGL262W 0.19 2.9
YJR157W 0.19 1.4
YER182W 0.19 1.4
YHR100C 0.19 0.8
YLR185W RPL37A 0.19 1.2 Homology to rat L37
YOR163W DDP1 0.19 1.3 Diadenosine and Diphosphoinositol Polyphosphate Phosphohydrolase
YLR426W 0.19 0.9
YCL033C 0.19 1.5
YIL136W OM45 0.19 2.0 45-kDa mitochondrial outer membrane protein
YOR339C UBC11 0.19 1.2 homolog of ubiquitin carrier protein E2-C
YJL189W RPL39 0.19 1.3 Homology to rat L39
YLL053C 0.19 1.3
YJL121C RPE1 0.19 1.0 D-ribulose-5-Phosphate 3-epimerase
YER007C-A 0.19 1.1
YBR128C APG14 0.19 1.0 Required for autophagy
YGR039W 0.19 1.9
YKL027W 0.19 0.8
YLR364W 0.19 1.1
YDR179W-A 0.19 2.5
YFL017C GNA1 0.19 1.7 involved in UDP-N-acetylglucosamine biosynthesis
YKR085C MRPL20 0.19 1.7 22.3 kDa mitochondrial ribosomal large subunit protein YmL20; homologous to L17 of E. coli
YDR204W COQ4 0.19 2.4 Involved in ubiquinone biosynthesis.
YNL056W 0.19 2.3 S
YHR180W 0.19 1.0
YGL103W RPL28 0.19 1.6 "Homology to rat, mouse L27a. May be involved in peptidyl transferase activity."
YBR111C YSA1 0.19 1.3 Protein with weak homology to D. melanogaster serendipity protein and X. laevis basis fibroblast growth factor
YNR046W 0.19 1.1
YAR008W SEN34 0.18 4.7 Z S C "tRNA splicing endonuclease 34kDa subunit; homologous to the 42-kDa subunit, SEN2; contains active site for 3' splice site cleavage"
YBR262C 0.18 1.6
YIL040W APQ12 0.18 0.9
YOL023W IFM1 0.18 1.3 mitochondrial initiation factor 2
YEL039C CYC7 0.18 2.2 iso-2-cytochrome c
YBL099W ATP1 0.18 1.4 mitochondrial F1F0-ATPase alpha subunit
YNL310C 0.18 1.9 C
YDR092W UBC13 0.18 1.6 ubiquitin-conjugating enzyme
YCR083W TRX3 0.18 1.6 mitochondrial thioredoxin
YIL164C NIT1 0.18 1.6 nitrilase
YLR327C 0.18 1.8
YKL071W 0.18 1.6
YPR107C YTH1 0.18 2.0 S Yeast 30kDa Homologue
YGR029W ERV1 0.18 1.1 "Protein forms dimers in vivo and in vitro, contains a conserved YPCXXC motif at carboxyl-terminal, binds FAD as a cofactor, and catalyzes the formation of disulfide bonds in protein substrates."
YBL036C 0.18 0.9
YOR318C 0.18 0.9
YHR049W FSH1 0.18 1.1
YBL112C 0.18 3.8 S
YER012W PRE1 0.18 1.2 Required for mitotic division and sporulation
YDL120W YFH1 0.18 1.4 Yeast Frataxin Homologue
YJR048W CYC1 0.18 2.5 S iso-1-cytochrome c
YMR326C 0.18 1.4
YAR061W 0.18 1.3
YHR059W FYV4 0.18 0.9 Function required for Yeast Viability on toxin exposure
YOR286W 0.18 1.7
YLR142W PUT1 0.18 3.7 S proline oxidase
YPL227C ALG5 0.17 2.0 UDP-glucose:dolichyl-phosphate glucosyltransferase
YEL024W RIP1 0.17 2.6 "oxidizes ubiquinol at center P in the protonmotive Q cycle mechanism, transferring one electron to cytochrome c1 and generating a low-potential ubisemiquinone anion which reduces the low-potential cytochrome b-566 heme group"
YMR095C SNO1 0.17 3.2 "SNZ1 proximal ORF, stationary phase induced gene"
YMR301C ATM1 0.17 1.0 mitochondrial ABC transporter protein
YLR289W GUF1 0.17 0.9 Similar to E. coli elongation factor-type GTP-binding protein LepA
YNL154C YCK2 0.17 0.9 membrane-bound casein kinase I homolog
YOL010W RCL1 0.17 1.1 protein similar to the RNA 3' terminal phosphate cyclase (RNA 3' terminal phosphate Cyclase-Like)
YLR010C TEN1 0.17 1.2 protein involved in Telomeric pathways in association with Stn1
YER163C 0.17 1.8
YOL147C PEX11 0.17 1.8 May promote peroxisomal proliferation by participating in peroxisomal elongation or fission or segregation of peroxisomes to daughter cells
YGL029W CGR1 0.17 1.4 Coiled-coil growth-regulated. May contribute to compartmentalization of nucleolar constituents.
YDR088C SLU7 0.17 1.6 Involved in 3' splice site choices and acts in concert with Prp18 during the 2nd step of splicing.
YLR068W FYV7 0.17 1.3 Function required for Yeast Viability on toxin exposure
YOR297C TIM18 0.17 1.2 mitochondrial inner membrane translocase
YIL077C 0.17 1.1
YAL049C 0.17 1.8
YMR083W ADH3 0.17 1.8 alcohol dehydrogenase isoenzyme III
YKR043C 0.16 1.2
YML078W CPR3 0.16 1.0 cyclophilin-3 (cyclosporin-sensitive proline rotamase-3)
YER112W LSM4 0.16 1.0 Like Sm-D3 protein
YJR111C 0.16 1.4
YLR305C STT4 0.16 1.1 "functions in the PKC1 protein kinase pathway, in a pathway with STT1 and MSS4"
YOL118C 0.16 2.6
YJL180C ATP12 0.16 1.8 essential for assembly of a functional F1-ATPase; binds the alpha subunit of F1-ATPase.
YGL080W 0.16 1.2
YDL125C HNT1 0.16 1.2 "Hint homolog, member of the histidine triad superfamily of nucleotide-binding proteins"
YOR122C PFY1 0.16 0.8 profilin (actin-binding protein)
YBR047W 0.16 1.0
YMR263W SAP30 0.16 1.9
YDR073W SNF11 0.15 1.6 component of SWI/SNF global transcription activator complex
YOR253W ARD2 0.15 0.8
YML050W 0.15 1.7 S
YIL134W FLX1 0.15 1.2 Nuclear-encoded mitochondrial protein involved in transport of flavine into mitochondria
YMR070W MOT3 0.15 1.4 High Copy Suppressor of MOT1-SPT3 synthetic lethality. May have a role in the regulation of membrane-related genes.
YPR051W MAK3 0.15 0.9 N-acetyltransferase
YMR267W PPA2 0.14 1.5 mitochondrial inorganic pyrophosphatase
YNL211C 0.14 0.8
YOL085C 0.13 1.4
YKL200C 1.3
YCR029C 1.4
YFL043C 2.0
YCLX07W 3.4
YKL158W 1.4
YDR134C 1.9
YCR097WB 1.3
YCRX18C 5.7
YCRX15W 0.9
YJL021C 1.2
YER108C 1.4
YCLX06C 1.9
YCLX10C 1.9
YCRX19W 2.2
YCRX21C 0.8
YCRX05W 3.0 S
YCR097WA 2.6
YAR074C 1.2
YCLX01W 1.3
YCR029C-A 0.8
YFL035C-B 1.2
YCRX12W 2.3 Z
YCL012W 6.0 Z S C
YCL026C 2.2
YCRX08W 1.3
YAR040C 2.2
YCRX03C 2.1
YCRX04W 1.8 C
YCRX09C 1.3
YCRX16C 1.2
YCR103C 1.6
YCRX06W 1.7
YCRX20C 1.7
YDL134C-A 0.1
YCRX11W 1.2
YCRX07W 1.5
YAR043C 1.5
YCRX01W 0.9
YCR056W 1.6
YCLX11W 1.4
YCR058C 1.6
YCL006C 1.0
YCR070W 1.6
YCLX04W 1.1
YCR074C 1.5
YCLX02C 1.5
YOR240W 1.5
YIL017W 1.0
YOR031W CRS5 1.4 Metallothionein-like protein
YCR080W 1.2
YCRX13W 1.1
YCLX03C 0.9
YCLX09W 3.2 S
YCLX12W 1.4
YCRX02C 1.0
YCL053C 1.4
YAR037W 1.4
YCL062W 3.6 Z S C
YFL035C-A 1.0
YCLX08C 1.1
YCR055C 1.0
YCL013W 5.3 Z S C
YCL003W 1.0
YCL021W 1.2
YCLX05C 1.8